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Volumn 14, Issue 1, 2013, Pages

PREDIVAC: CD4+ T-cell epitope prediction for vaccine design that covers 95% of HLA class II DR protein diversity

Author keywords

CD4+ T cell epitope prediction; Epitope based vaccination; Immunodominance; MHC (HLA) class II polymorphism; MHC (HLA) class II proteins; Pan specific; Peptide binding prediction; Peptide vaccination, Specificity determining residues

Indexed keywords

CLASS II; EPITOPE-BASED VACCINATION; IMMUNODOMINANCE; PAN-SPECIFIC; PEPTIDE BINDING; T-CELL EPITOPES;

EID: 84873599312     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-14-52     Document Type: Article
Times cited : (54)

References (53)
  • 2
    • 77956217622 scopus 로고    scopus 로고
    • A vaccine encoding conserved promiscuous HIV CD4 epitopes induces broad T cell responses in mice transgenic to multiple common HLA class II molecules
    • 10.1371/journal.pone.0011072, 2884037, 20552033
    • Ribeiro SP, Rosa DS, Fonseca SG, Mairena EC, Postol E, Oliveira SC, Guilherme L, Kalil J, Cunha-Neto E. A vaccine encoding conserved promiscuous HIV CD4 epitopes induces broad T cell responses in mice transgenic to multiple common HLA class II molecules. PLoS One 2010, 5(6):e11072. 10.1371/journal.pone.0011072, 2884037, 20552033.
    • (2010) PLoS One , vol.5 , Issue.6
    • Ribeiro, S.P.1    Rosa, D.S.2    Fonseca, S.G.3    Mairena, E.C.4    Postol, E.5    Oliveira, S.C.6    Guilherme, L.7    Kalil, J.8    Cunha-Neto, E.9
  • 3
    • 0031572833 scopus 로고    scopus 로고
    • The class II MHC protein HLA-DR1 in complex with an endogenous peptide: implications for the structural basis of the specificity of peptide binding
    • 10.1016/S0969-2126(97)00288-8, 9351812
    • Murthy VL, Stern LJ. The class II MHC protein HLA-DR1 in complex with an endogenous peptide: implications for the structural basis of the specificity of peptide binding. Structure 1997, 5(10):1385-1396. 10.1016/S0969-2126(97)00288-8, 9351812.
    • (1997) Structure , vol.5 , Issue.10 , pp. 1385-1396
    • Murthy, V.L.1    Stern, L.J.2
  • 5
    • 33846662153 scopus 로고    scopus 로고
    • Identifying HLA supertypes by learning distance functions
    • 10.1093/Bioinformatics/btl324, 17237084
    • Hertz T, Yanover C. Identifying HLA supertypes by learning distance functions. Bioinformatics 2007, 23(2):e148-e155. 10.1093/Bioinformatics/btl324, 17237084.
    • (2007) Bioinformatics , vol.23 , Issue.2
    • Hertz, T.1    Yanover, C.2
  • 7
    • 5444249860 scopus 로고    scopus 로고
    • Enhancement to the RANKPEP resource for the prediction of peptide binding to MHC molecules using profiles
    • Reche PA, Glutting JP, Zhang H, Reinherz EL. Enhancement to the RANKPEP resource for the prediction of peptide binding to MHC molecules using profiles. Immunogenetics 2004, 56(6):405-419.
    • (2004) Immunogenetics , vol.56 , Issue.6 , pp. 405-419
    • Reche, P.A.1    Glutting, J.P.2    Zhang, H.3    Reinherz, E.L.4
  • 9
    • 34547778364 scopus 로고    scopus 로고
    • Prediction of MHC class II binding affinity using SMM-align, a novel stabilization matrix alignment method
    • Nielsen M, Lundegaard C, Lund O. Prediction of MHC class II binding affinity using SMM-align, a novel stabilization matrix alignment method. BMC Bioinforma 2007, 8:238.
    • (2007) BMC Bioinforma , vol.8 , pp. 238
    • Nielsen, M.1    Lundegaard, C.2    Lund, O.3
  • 11
    • 84863182833 scopus 로고    scopus 로고
    • TEPITOPEpan: extending TEPITOPE for peptide binding prediction covering over 700 HLA-DR molecules
    • 10.1371/journal.pone.0030483, 3285624, 22383964
    • Zhang L, Chen Y, Wong HS, Zhou S, Mamitsuka H, Zhu S. TEPITOPEpan: extending TEPITOPE for peptide binding prediction covering over 700 HLA-DR molecules. PLoS One 2012, 7(2):e30483. 10.1371/journal.pone.0030483, 3285624, 22383964.
    • (2012) PLoS One , vol.7 , Issue.2
    • Zhang, L.1    Chen, Y.2    Wong, H.S.3    Zhou, S.4    Mamitsuka, H.5    Zhu, S.6
  • 12
    • 77956922389 scopus 로고    scopus 로고
    • MultiRTA: a simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes
    • Bordner AJ, Mittelmann HD. MultiRTA: a simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes. BMC Bioinforma 2010, 11:482.
    • (2010) BMC Bioinforma , vol.11 , pp. 482
    • Bordner, A.J.1    Mittelmann, H.D.2
  • 13
    • 70449359806 scopus 로고    scopus 로고
    • NN-align. An artificial neural network-based alignment algorithm for MHC class II peptide binding prediction
    • Nielsen M, Lund O. NN-align. An artificial neural network-based alignment algorithm for MHC class II peptide binding prediction. BMC Bioinforma 2009, 10:296.
    • (2009) BMC Bioinforma , vol.10 , pp. 296
    • Nielsen, M.1    Lund, O.2
  • 14
    • 78149354807 scopus 로고    scopus 로고
    • NetMHCIIpan-2.0 - Improved pan-specific HLA-DR predictions using a novel concurrent alignment and weight optimization training procedure
    • 10.1186/1745-7580-6-9, 2994798, 21073747
    • Nielsen M, Justesen S, Lund O, Lundegaard C, Buus S. NetMHCIIpan-2.0 - Improved pan-specific HLA-DR predictions using a novel concurrent alignment and weight optimization training procedure. Immunome Res 2010, 6:9. 10.1186/1745-7580-6-9, 2994798, 21073747.
    • (2010) Immunome Res , vol.6 , pp. 9
    • Nielsen, M.1    Justesen, S.2    Lund, O.3    Lundegaard, C.4    Buus, S.5
  • 17
    • 83155180577 scopus 로고    scopus 로고
    • Toward more accurate pan-specific MHC-peptide binding prediction: a review of current methods and tools
    • 10.1093/bib/bbr060, 21949215
    • Zhang L, Udaka K, Mamitsuka H, Zhu S. Toward more accurate pan-specific MHC-peptide binding prediction: a review of current methods and tools. Brief Bioinform 2012, 13(3):350-364. 10.1093/bib/bbr060, 21949215.
    • (2012) Brief Bioinform , vol.13 , Issue.3 , pp. 350-364
    • Zhang, L.1    Udaka, K.2    Mamitsuka, H.3    Zhu, S.4
  • 18
    • 0037422596 scopus 로고    scopus 로고
    • Structural basis and prediction of substrate specificity in protein serine/threonine kinases
    • 10.1073/pnas.0134224100, 140887, 12502784
    • Brinkworth RI, Breinl RA, Kobe B. Structural basis and prediction of substrate specificity in protein serine/threonine kinases. Proc Natl Acad Sci USA 2003, 100(1):74-79. 10.1073/pnas.0134224100, 140887, 12502784.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.1 , pp. 74-79
    • Brinkworth, R.I.1    Breinl, R.A.2    Kobe, B.3
  • 19
    • 44849086809 scopus 로고    scopus 로고
    • Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated database of phosphorylation sites
    • Saunders NF, Brinkworth RI, Huber T, Kemp BE, Kobe B. Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated database of phosphorylation sites. BMC Bioinforma 2008, 9:245.
    • (2008) BMC Bioinforma , vol.9 , pp. 245
    • Saunders, N.F.1    Brinkworth, R.I.2    Huber, T.3    Kemp, B.E.4    Kobe, B.5
  • 20
    • 79960876979 scopus 로고    scopus 로고
    • Predicting protein kinase specificity: Predikin update and performance in the DREAM4 challenge
    • 10.1371/journal.pone.0021169, 3145639, 21829434
    • Ellis JJ, Kobe B. Predicting protein kinase specificity: Predikin update and performance in the DREAM4 challenge. PLoS One 2011, 6(7):e21169. 10.1371/journal.pone.0021169, 3145639, 21829434.
    • (2011) PLoS One , vol.6 , Issue.7
    • Ellis, J.J.1    Kobe, B.2
  • 21
    • 80051505743 scopus 로고    scopus 로고
    • Identification of specificity determining residues in peptide recognition domains using an information theoretic approach applied to large-scale binding maps
    • 10.1186/1741-7007-9-53, 3224579, 21835011
    • Yip KY, Utz L, Sitwell S, Hu X, Sidhu SS, Turk BE, Gerstein M, Kim PM. Identification of specificity determining residues in peptide recognition domains using an information theoretic approach applied to large-scale binding maps. BMC Biol 2011, 9:53. 10.1186/1741-7007-9-53, 3224579, 21835011.
    • (2011) BMC Biol , vol.9 , pp. 53
    • Yip, K.Y.1    Utz, L.2    Sitwell, S.3    Hu, X.4    Sidhu, S.S.5    Turk, B.E.6    Gerstein, M.7    Kim, P.M.8
  • 22
    • 77954554764 scopus 로고    scopus 로고
    • An automated stochastic approach to the identification of the protein specificity determinants and functional subfamilies
    • 10.1186/1748-7188-5-29, 2914642, 20633297
    • Mazin PV, Gelfand MS, Mironov AA, Rakhmaninova AB, Rubinov AR, Russell RB, Kalinina OV. An automated stochastic approach to the identification of the protein specificity determinants and functional subfamilies. Algorithms Mol Biol 2010, 5:29. 10.1186/1748-7188-5-29, 2914642, 20633297.
    • (2010) Algorithms Mol Biol , vol.5 , pp. 29
    • Mazin, P.V.1    Gelfand, M.S.2    Mironov, A.A.3    Rakhmaninova, A.B.4    Rubinov, A.R.5    Russell, R.B.6    Kalinina, O.V.7
  • 23
    • 0034635976 scopus 로고    scopus 로고
    • Predicting ligand-binding function in families of bacterial receptors
    • 10.1073/pnas.050580897, 18125, 10737762
    • Johnson JM, Church GM. Predicting ligand-binding function in families of bacterial receptors. Proc Natl Acad Sci USA 2000, 97(8):3965-3970. 10.1073/pnas.050580897, 18125, 10737762.
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.8 , pp. 3965-3970
    • Johnson, J.M.1    Church, G.M.2
  • 24
    • 84866925795 scopus 로고    scopus 로고
    • Computational modelling of linear motif-mediated protein interactions
    • 10.2174/156802612802652439, 22827524
    • Kobe B, Boden M. Computational modelling of linear motif-mediated protein interactions. Curr Top Med Chem 2012, 12(14):1553-1561. 10.2174/156802612802652439, 22827524.
    • (2012) Curr Top Med Chem , vol.12 , Issue.14 , pp. 1553-1561
    • Kobe, B.1    Boden, M.2
  • 25
    • 67749099405 scopus 로고    scopus 로고
    • High-energy water sites determine peptide binding affinity and specificity of PDZ domains
    • 10.1002/pro.177, 2776949, 19569188
    • Beuming T, Farid R, Sherman W. High-energy water sites determine peptide binding affinity and specificity of PDZ domains. Protein Sci 2009, 18(8):1609-1619. 10.1002/pro.177, 2776949, 19569188.
    • (2009) Protein Sci , vol.18 , Issue.8 , pp. 1609-1619
    • Beuming, T.1    Farid, R.2    Sherman, W.3
  • 26
    • 84860320829 scopus 로고    scopus 로고
    • The utility and limitations of current Web-available algorithms to predict peptides recognized by CD4 T cells in response to pathogen infection
    • 10.4049/jimmunol.1103640, 22467652
    • Chaves FA, Lee AH, Nayak JL, Richards KA, Sant AJ. The utility and limitations of current Web-available algorithms to predict peptides recognized by CD4 T cells in response to pathogen infection. J Immunol 2012, 188(9):4235-4248. 10.4049/jimmunol.1103640, 22467652.
    • (2012) J Immunol , vol.188 , Issue.9 , pp. 4235-4248
    • Chaves, F.A.1    Lee, A.H.2    Nayak, J.L.3    Richards, K.A.4    Sant, A.J.5
  • 27
    • 34250372499 scopus 로고    scopus 로고
    • Immunodominance in CD4 T-cell responses: implications for immune responses to influenza virus and for vaccine design
    • 10.1586/14760584.6.3.357, 17542751
    • Sant AJ, Chaves FA, Krafcik FR, Lazarski CA, Menges P, Richards K, Weaver JM. Immunodominance in CD4 T-cell responses: implications for immune responses to influenza virus and for vaccine design. Expert Rev Vaccines 2007, 6(3):357-368. 10.1586/14760584.6.3.357, 17542751.
    • (2007) Expert Rev Vaccines , vol.6 , Issue.3 , pp. 357-368
    • Sant, A.J.1    Chaves, F.A.2    Krafcik, F.R.3    Lazarski, C.A.4    Menges, P.5    Richards, K.6    Weaver, J.M.7
  • 28
    • 24744453723 scopus 로고    scopus 로고
    • Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes
    • Schulze Zur Wiesch J, Lauer GM, Day CL, Kim AY, Ouchi K, Duncan JE, Wurcel AG, Timm J, Jones AM, Mothe B, et al. Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes. J Immunol 2005, 175(6):3603-3613.
    • (2005) J Immunol , vol.175 , Issue.6 , pp. 3603-3613
    • Schulze Zur Wiesch, J.1    Lauer, G.M.2    Day, C.L.3    Kim, A.Y.4    Ouchi, K.5    Duncan, J.E.6    Wurcel, A.G.7    Timm, J.8    Jones, A.M.9    Mothe, B.10
  • 30
    • 51549100883 scopus 로고    scopus 로고
    • Immunodominance of CD4 T cells to foreign antigens is peptide intrinsic and independent of molecular context: implications for vaccine design
    • 2814425, 18713974
    • Weaver JM, Lazarski CA, Richards KA, Chaves FA, Jenks SA, Menges PR, Sant AJ. Immunodominance of CD4 T cells to foreign antigens is peptide intrinsic and independent of molecular context: implications for vaccine design. J Immunol 2008, 181(5):3039-3048. 2814425, 18713974.
    • (2008) J Immunol , vol.181 , Issue.5 , pp. 3039-3048
    • Weaver, J.M.1    Lazarski, C.A.2    Richards, K.A.3    Chaves, F.A.4    Jenks, S.A.5    Menges, P.R.6    Sant, A.J.7
  • 31
    • 78651096072 scopus 로고    scopus 로고
    • Innovative bioinformatic approaches for developing peptide-based vaccines against hypervariable viruses
    • 10.1038/icb.2010.65, 20458336
    • Sirskyj D, Diaz-Mitoma F, Golshani A, Kumar A, Azizi A. Innovative bioinformatic approaches for developing peptide-based vaccines against hypervariable viruses. Immunol Cell Biol 2011, 89(1):81-89. 10.1038/icb.2010.65, 20458336.
    • (2011) Immunol Cell Biol , vol.89 , Issue.1 , pp. 81-89
    • Sirskyj, D.1    Diaz-Mitoma, F.2    Golshani, A.3    Kumar, A.4    Azizi, A.5
  • 32
    • 0029878720 scopus 로고    scopus 로고
    • VMD: visual molecular dynamics
    • 27-38, 10.1016/0263-7855(96)00018-5, 8744570
    • Humphrey W, Dalke A, Schulten K. VMD: visual molecular dynamics. J Mol Graph 1996, 14(1):33-38. 27-38, 10.1016/0263-7855(96)00018-5, 8744570.
    • (1996) J Mol Graph , vol.14 , Issue.1 , pp. 33-38
    • Humphrey, W.1    Dalke, A.2    Schulten, K.3
  • 33
    • 48449095267 scopus 로고    scopus 로고
    • PVS: a web server for protein sequence variability analysis tuned to facilitate conserved epitope discovery
    • 2447719, 18442995
    • Garcia-Boronat M, Diez-Rivero CM, Reinherz EL, Reche PA. PVS: a web server for protein sequence variability analysis tuned to facilitate conserved epitope discovery. Nucleic Acids Res 2008, 36(Web Server issue):W35-41. 2447719, 18442995.
    • (2008) Nucleic Acids Res , vol.36 , Issue.WEB SERVER ISSUE
    • Garcia-Boronat, M.1    Diez-Rivero, C.M.2    Reinherz, E.L.3    Reche, P.A.4
  • 34
    • 77954717016 scopus 로고    scopus 로고
    • Quantum chemical analysis of MHC-peptide interactions for vaccine design
    • 10.2174/138955710791572488, 3182080, 20394575
    • Agudelo WA, Patarroyo ME. Quantum chemical analysis of MHC-peptide interactions for vaccine design. Mini Rev Med Chem 2010, 10(8):746-758. 10.2174/138955710791572488, 3182080, 20394575.
    • (2010) Mini Rev Med Chem , vol.10 , Issue.8 , pp. 746-758
    • Agudelo, W.A.1    Patarroyo, M.E.2
  • 36
    • 75849149663 scopus 로고    scopus 로고
    • MHCBN 4.0: a database of MHC/TAP binding peptides and T-cell epitopes
    • 10.1186/1756-0500-2-61, 2679046, 19379493
    • Lata S, Bhasin M, Raghava GP. MHCBN 4.0: a database of MHC/TAP binding peptides and T-cell epitopes. BMC Res Notes 2009, 2:61. 10.1186/1756-0500-2-61, 2679046, 19379493.
    • (2009) BMC Res Notes , vol.2 , pp. 61
    • Lata, S.1    Bhasin, M.2    Raghava, G.P.3
  • 37
    • 18744368784 scopus 로고    scopus 로고
    • EPIMHC: a curated database of MHC-binding peptides for customized computational vaccinology
    • 10.1093/bioinformatics/bti269, 15657103
    • Reche PA, Zhang H, Glutting JP, Reinherz EL. EPIMHC: a curated database of MHC-binding peptides for customized computational vaccinology. Bioinformatics 2005, 21(9):2140-2141. 10.1093/bioinformatics/bti269, 15657103.
    • (2005) Bioinformatics , vol.21 , Issue.9 , pp. 2140-2141
    • Reche, P.A.1    Zhang, H.2    Glutting, J.P.3    Reinherz, E.L.4
  • 38
    • 2442499729 scopus 로고    scopus 로고
    • Improved prediction of MHC class I and class II epitopes using a novel Gibbs sampling approach
    • 10.1093/bioinformatics/bth100, 14962912
    • Nielsen M, Lundegaard C, Worning P, Hvid CS, Lamberth K, Buus S, Brunak S, Lund O. Improved prediction of MHC class I and class II epitopes using a novel Gibbs sampling approach. Bioinformatics 2004, 20(9):1388-1397. 10.1093/bioinformatics/bth100, 14962912.
    • (2004) Bioinformatics , vol.20 , Issue.9 , pp. 1388-1397
    • Nielsen, M.1    Lundegaard, C.2    Worning, P.3    Hvid, C.S.4    Lamberth, K.5    Buus, S.6    Brunak, S.7    Lund, O.8
  • 39
    • 77949352951 scopus 로고    scopus 로고
    • The MHC motif viewer: a visualization tool for MHC binding motifs
    • Chapter 18:Unit 18 17
    • Rapin N, Hoof I, Lund O, Nielsen M. The MHC motif viewer: a visualization tool for MHC binding motifs. Curr Protoc Immunol 2010, Chapter 18:Unit 18 17.
    • (2010) Curr Protoc Immunol
    • Rapin, N.1    Hoof, I.2    Lund, O.3    Nielsen, M.4
  • 40
    • 0042665284 scopus 로고    scopus 로고
    • Sequence variability analysis of human class I and class II MHC molecules: functional and structural correlates of amino acid polymorphisms
    • 10.1016/S0022-2836(03)00750-2, 12899833
    • Reche PA, Reinherz EL. Sequence variability analysis of human class I and class II MHC molecules: functional and structural correlates of amino acid polymorphisms. J Mol Biol 2003, 331(3):623-641. 10.1016/S0022-2836(03)00750-2, 12899833.
    • (2003) J Mol Biol , vol.331 , Issue.3 , pp. 623-641
    • Reche, P.A.1    Reinherz, E.L.2
  • 41
    • 48249083459 scopus 로고    scopus 로고
    • Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan
    • 10.1371/journal.pcbi.1000107, 2430535, 18604266
    • Nielsen M, Lundegaard C, Blicher T, Peters B, Sette A, Justesen S, Buus S, Lund O. Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan. PLoS Comput Biol 2008, 4(7):e1000107. 10.1371/journal.pcbi.1000107, 2430535, 18604266.
    • (2008) PLoS Comput Biol , vol.4 , Issue.7
    • Nielsen, M.1    Lundegaard, C.2    Blicher, T.3    Peters, B.4    Sette, A.5    Justesen, S.6    Buus, S.7    Lund, O.8
  • 42
    • 81255136087 scopus 로고    scopus 로고
    • Dana-Farber repository for machine learning in immunology
    • 3249226, 21782820
    • Zhang GL, Lin HH, Keskin DB, Reinherz EL, Brusic V. Dana-Farber repository for machine learning in immunology. J Immunol Methods 2011, 374(1-2):18-25. 3249226, 21782820.
    • (2011) J Immunol Methods , vol.374 , Issue.1-2 , pp. 18-25
    • Zhang, G.L.1    Lin, H.H.2    Keskin, D.B.3    Reinherz, E.L.4    Brusic, V.5
  • 43
    • 57649174707 scopus 로고    scopus 로고
    • Evaluation of MHC-II peptide binding prediction servers: applications for vaccine research
    • Lin HH, Zhang GL, Tongchusak S, Reinherz EL, Brusic V. Evaluation of MHC-II peptide binding prediction servers: applications for vaccine research. BMC Bioinforma 2008, 9(Suppl 12):S22.
    • (2008) BMC Bioinforma , vol.9 , Issue.SUPPL. 12
    • Lin, H.H.1    Zhang, G.L.2    Tongchusak, S.3    Reinherz, E.L.4    Brusic, V.5
  • 44
    • 33748784872 scopus 로고    scopus 로고
    • Antigen three-dimensional structure guides the processing and presentation of helper T-cell epitopes
    • 10.1016/j.molimm.2006.06.014, 16893568
    • Carmicle S, Steede NK, Landry SJ. Antigen three-dimensional structure guides the processing and presentation of helper T-cell epitopes. Mol Immunol 2007, 44(6):1159-1168. 10.1016/j.molimm.2006.06.014, 16893568.
    • (2007) Mol Immunol , vol.44 , Issue.6 , pp. 1159-1168
    • Carmicle, S.1    Steede, N.K.2    Landry, S.J.3
  • 45
    • 22544455376 scopus 로고    scopus 로고
    • The kinetic stability of MHC class II:peptide complexes is a key parameter that dictates immunodominance
    • 10.1016/j.immuni.2005.05.009, 16039577
    • Lazarski CA, Chaves FA, Jenks SA, Wu S, Richards KA, Weaver JM, Sant AJ. The kinetic stability of MHC class II:peptide complexes is a key parameter that dictates immunodominance. Immunity 2005, 23(1):29-40. 10.1016/j.immuni.2005.05.009, 16039577.
    • (2005) Immunity , vol.23 , Issue.1 , pp. 29-40
    • Lazarski, C.A.1    Chaves, F.A.2    Jenks, S.A.3    Wu, S.4    Richards, K.A.5    Weaver, J.M.6    Sant, A.J.7
  • 46
    • 22544482556 scopus 로고    scopus 로고
    • The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes
    • 10.1111/j.0105-2896.2005.00307.x, 16181342
    • Sant AJ, Chaves FA, Jenks SA, Richards KA, Menges P, Weaver JM, Lazarski CA. The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes. Immunol Rev 2005, 207:261-278. 10.1111/j.0105-2896.2005.00307.x, 16181342.
    • (2005) Immunol Rev , vol.207 , pp. 261-278
    • Sant, A.J.1    Chaves, F.A.2    Jenks, S.A.3    Richards, K.A.4    Menges, P.5    Weaver, J.M.6    Lazarski, C.A.7
  • 47
    • 77957744887 scopus 로고    scopus 로고
    • Repertoire of HLA-DR1-restricted CD4 T-cell responses to capsular Caf1 antigen of Yersinia pestis in human leukocyte antigen transgenic mice
    • 10.1128/IAI.00195-10, 2950366, 20660611
    • Musson JA, Ingram R, Durand G, Ascough S, Waters EL, Hartley MG, Robson T, Maillere B, Williamson ED, Sriskandan S, et al. Repertoire of HLA-DR1-restricted CD4 T-cell responses to capsular Caf1 antigen of Yersinia pestis in human leukocyte antigen transgenic mice. Infect Immun 2010, 78(10):4356-4362. 10.1128/IAI.00195-10, 2950366, 20660611.
    • (2010) Infect Immun , vol.78 , Issue.10 , pp. 4356-4362
    • Musson, J.A.1    Ingram, R.2    Durand, G.3    Ascough, S.4    Waters, E.L.5    Hartley, M.G.6    Robson, T.7    Maillere, B.8    Williamson, E.D.9    Sriskandan, S.10
  • 48
    • 78049403279 scopus 로고    scopus 로고
    • Ligand binding assays at equilibrium: validation and interpretation
    • 10.1111/j.1476-5381.2009.00604.x, 3000649, 20132208
    • Hulme EC, Trevethick MA. Ligand binding assays at equilibrium: validation and interpretation. Br J Pharmacol 2010, 161(6):1219-1237. 10.1111/j.1476-5381.2009.00604.x, 3000649, 20132208.
    • (2010) Br J Pharmacol , vol.161 , Issue.6 , pp. 1219-1237
    • Hulme, E.C.1    Trevethick, M.A.2
  • 50
    • 0034620590 scopus 로고    scopus 로고
    • Kinetics of peptide binding to the class II MHC protein I-Ek
    • 10.1021/bi9921337, 10653650
    • Kasson PM, Rabinowitz JD, Schmitt L, Davis MM, McConnell HM. Kinetics of peptide binding to the class II MHC protein I-Ek. Biochemistry 2000, 39(5):1048-1058. 10.1021/bi9921337, 10653650.
    • (2000) Biochemistry , vol.39 , Issue.5 , pp. 1048-1058
    • Kasson, P.M.1    Rabinowitz, J.D.2    Schmitt, L.3    Davis, M.M.4    McConnell, H.M.5
  • 51
    • 4043176043 scopus 로고    scopus 로고
    • Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides
    • 10.1128/JVI.78.9.4463-4477.2004, 387674, 15078927
    • Kaufmann DE, Bailey PM, Sidney J, Wagner B, Norris PJ, Johnston MN, Cosimi LA, Addo MM, Lichterfeld M, Altfeld M, et al. Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides. J Virol 2004, 78(9):4463-4477. 10.1128/JVI.78.9.4463-4477.2004, 387674, 15078927.
    • (2004) J Virol , vol.78 , Issue.9 , pp. 4463-4477
    • Kaufmann, D.E.1    Bailey, P.M.2    Sidney, J.3    Wagner, B.4    Norris, P.J.5    Johnston, M.N.6    Cosimi, L.A.7    Addo, M.M.8    Lichterfeld, M.9    Altfeld, M.10
  • 52
    • 36048970545 scopus 로고    scopus 로고
    • Human CD4+ T cell epitopes from vaccinia virus induced by vaccination or infection
    • 2014795, 17937498
    • Calvo-Calle JM, Strug I, Nastke MD, Baker SP, Stern LJ. Human CD4+ T cell epitopes from vaccinia virus induced by vaccination or infection. PLoS Pathog 2007, 3(10):1511-1529. 2014795, 17937498.
    • (2007) PLoS Pathog , vol.3 , Issue.10 , pp. 1511-1529
    • Calvo-Calle, J.M.1    Strug, I.2    Nastke, M.D.3    Baker, S.P.4    Stern, L.J.5
  • 53
    • 4444256379 scopus 로고    scopus 로고
    • A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition
    • 10.1073/pnas.0403371101, 516560, 15331779
    • Zavala-Ruiz Z, Strug I, Walker BD, Norris PJ, Stern LJ. A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition. Proc Natl Acad Sci USA 2004, 101(36):13279-13284. 10.1073/pnas.0403371101, 516560, 15331779.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.36 , pp. 13279-13284
    • Zavala-Ruiz, Z.1    Strug, I.2    Walker, B.D.3    Norris, P.J.4    Stern, L.J.5


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