An Efficient Procedure for Marker-Free Mutagenesis of S. coelicolor by Site-Specific Recombination for Secondary Metabolite Overproduction

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Zhang, Bo ^a   Zhang, Lin ^a,b   Dai, Ruixue ^a   Yu, Meiying ^a   Zhao, Guoping ^a,b,c,d   Ding, Xiaoming ^a  

^a FUDAN UNIVERSITY   (China)

^b INSTITUTE OF PLANT PHYSIOLOGY AND ECOLOGY   (China)

^c CHINESE NATIONAL HUMAN GENOME CENTER AT SHANGHAI   (China)

^d CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ACTINORHODINE; CALCIUM DEPENDENT ANTIBIOTIC; INTEGRASE; NATURAL PRODUCT; PLASMID VECTOR; PRODIGININE; UNCLASSIFIED DRUG;

ARTICLE; ATTB GENE; ATTP GENE; BACTERIAL STRAIN; BACTERIOPHAGE; BIOSYNTHESIS; CONTROLLED STUDY; EXPRESSION VECTOR; GENE; GENE CLUSTER; GENE CONSTRUCT; GENE DELETION; GENE TARGETING; GENE VECTOR; GENETIC ENGINEERING; GENETIC RECOMBINATION; GENOME ANALYSIS; IN VITRO STUDY; METABOLITE; MOLECULAR CLONING; NONHUMAN; RRDA GENE; SITE DIRECTED MUTAGENESIS; STREPTOMYCES COELICOLOR; WILD TYPE;

ANTHRAQUINONES; GENE DELETION; GENE ORDER; GENE TARGETING; GENES, BACTERIAL; GENETIC VECTORS; HOMOLOGOUS RECOMBINATION; MUTAGENESIS; MUTATION; PHENOTYPE; PRODIGIOSIN; STREPTOMYCES;

EID: 84873587301     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055906     Document Type: Article

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