Merck's perspective on the implementation of dried blood spot technology in clinical drug development - Why, when and how

Bioanalysis

Volumn 5, Issue 3, 2013, Pages 341-350

  Xu, Yang ^a   Woolf, Eric J ^a   Agrawal, Nancy G B ^a   Kothare, Prajakti ^a   Pucci, Vincenzo ^a   Bateman, Kevin P ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG; PLASMA PROTEIN;

ACCURACY; ALGORITHM; ANALYTIC METHOD; BIOLOGICAL MONITORING; BIOTECHNOLOGY; BLOOD ANALYSIS; BLOOD CELL; BLOOD SAMPLING; BLOOD TO PLASMA RATIO; CELL SEPARATION; CLINICAL LABORATORY; DATA ANALYSIS; DECISION MAKING; DRIED BLOOD SPOT TECHNOLOGY; DRIED BLOOD SPOT TESTING; DRUG BLOOD LEVEL; DRUG DEVELOPMENT; DRUG INDUSTRY; DRUG METABOLISM; DRUG RESEARCH; FEASIBILITY STUDY; HEMATOCRIT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VITRO STUDY; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACODYNAMICS; PHARMACOKINETICS; PHARMACOLOGICAL PARAMETERS; PHYSICAL CHEMISTRY; PROBABILITY; QUALITY CONTROL; REVIEW; STANDARDIZATION; STORAGE;

BLOOD SPECIMEN COLLECTION; DRIED BLOOD SPOT TESTING; DRUG DESIGN; DRUG DISCOVERY; DRUG INDUSTRY; HUMANS; SPECIMEN HANDLING;

EID: 84873583377     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.12.321     Document Type: Review

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