The analysis of dried blood spot samples using liquid chromatography tandem mass spectrometry

Clinical Biochemistry

Volumn 44, Issue 1, 2011, Pages 110-118

  Keevil, Brian G ^a  

^a MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Dried blood spot; LC MS MS

Indexed keywords

ACETONITRILE; ACYLCARNITINE; AMINO ACID; BILE ACID; CARBAMOYL PHOSPHATE; CARBOXYLIC ACID; CARNITINE DERIVATIVE; CERULOPLASMIN; CORTODOXONE; CYCLOSPORIN A; DICARBOXYLIC ACID; DODECYL SULFATE SODIUM; EVEROLIMUS; FATTY ACID; GLUTAMIC ACID; GLUTAMINE; HYDRAZINE; ISOBUTANOL; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE; METHYLMALONIC ACID; ORNITHINE CARBAMOYLTRANSFERASE; PROPIONYLCARNITINE; RAPAMYCIN; STEROID 21 MONOOXYGENASE; SUCCINYLACETONE; TACROLIMUS; THYROTROPIN; THYROXINE; TRYPSIN; UNINDEXED DRUG;

AMINO ACID BLOOD LEVEL; BLOOD COMPONENT; BLOOD SAMPLING; CALIBRATION; CAPILLARY BLOOD; CONGENITAL HYPOTHYROIDISM; FILTER; HOMOCYSTINURIA; HUMAN; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; METABOLIC DISORDER; PEPTIDE ANALYSIS; PHENYLKETONURIA; PRIORITY JOURNAL; REVIEW; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; STEROID 21 MONOOXYGENASE DEFICIENCY; TANDEM MASS SPECTROMETRY;

BLOOD CHEMICAL ANALYSIS; BLOOD SPECIMEN COLLECTION; CHROMATOGRAPHY, LIQUID; HUMANS; TANDEM MASS SPECTROMETRY;

EID: 78650898984     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2010.06.014     Document Type: Review

References (49)

1. Chace D.H., Millington D.S., Terada N., Kahler S.G., Roe C.R., Hofman L.F. Rapid diagnosis of phenylketonuria by quantitative analysis for phenylalanine and tyrosine in neonatal blood spots by tandem mass spectrometry. Clin Chem 1993, 39:66-71.
2. Edelbrook P.M., Heijden J.van der, Stolk L.M.L. Dried blood spot methods in therapeutic drug monitoring: methods, assays and pitfalls. Ther Drug Monit 2009, 31:327-336.
3. Merton G., Jones K., Lee M., Johnston A., Holt D.W. Accuracy of cyclosporine measurements made in capillary blood samples obtained by skin puncture. Ther Drug Monit 2000, 22:594-598.
4. Woods K., Douketis J.D., Schnurr T., Kinnon K., Powers P., Crowther M.A. Patient preferences for capillary vs venous INR determination in an anticoagulation clinic: a randomized controlled trial. Thromb Res 2004, 114:161-165.
5. Kupke R., Kather B., Zeugner S. On the composition of capillary and venous blood serum. Clin Chim Acta 1981, 112:177-185.
6. Mei J.V., Alexander J.R., Adams B.W., et al. Use of filter paper for the collection and analysis of human whole blood specimens. J Nutr 2001, 131(9):1631S-1636S.
7. National Committee on Clinical Laboratory Standards (NNCLS), now known as Clinical Laboratory Standards Institute (CLSI): LA4-A4 "Blood Collection on Filter Paper for Newborn Screening Programs; Approved Standard - Fourth Edition.
8. Chace D.H., Hillman S.L., Millington D.S., Kahler C.R., Naylor E.W. Rapid diagnosis of maple syrup urine disease in blood spots from newborns by tandem mass spectrometry. Clin Chem 1995, 41:62-68.
9. Chace D.H., Hillman S.L., Millington D.S., Kahler S.G., Adam B.W., Levy H.L. Rapid diagnosis of homocystinuria and other methioninemias from newborns' blood spots by tandem mass spectrometry. Clin Chem 1996, 42:349-355.
10. Rashed M.S., Ozand P.T., Bucknall M.P., Little D. Diagnosis of inborn errors of metabolism from blood spots by acylcarnitines and amino acids profiling using automated electrospray tandem mass spectrometry. Pediatr Res 1995, 38:324-331.
11. Chace D.H., Hillman S.L., van Hove J.L.K., Naylor E.W. Rapid diagnosis of MCAD deficiency: quantitative analysis of octanoylcarnitine and other acylcarnitines in newborn blood spots by tandem mass spectrometry. Clin Chem 1997, 43:2106-2113.
12. Rashed M.S., Bucknall M.P., Little D., Awad A., Jacob M., Alamoudi M., et al. Screening blood spots for inborn errors of metabolism by electrospray tandem mass spectrometry with a microbatch process and a computer algorithm for automated flagging of abnormal profiles. Clin Chem 1997, 43:1129-1141.
13. Oglesbee D., Sanders K.A., Lacey J.M., Magera M.J., Casetta B., Strauss K.A., Tortorelli S., Rinaldo P., Matern D. Second-tier test for quantification of alloisoleucine and branched-chain amino acids in dried blood spots to improve newborn screening for maple syrup urine disease (MSUD). Clin Chem 2008, 54:542-549.
14. Qu J., Chen W., Luo G., Wang Y., Xiao S., Ling Z., Chen G. Rapid determination of underivatized pyroglutamic acid, glutamic acid, glutamine and other relevant amino acids in fermentation media by LC-MS-MS. Analyst 2002, 127:66-69.
15. Johnson D.W. Analysis of amino acids as formamidene butyl esters by electrospray ionization tandem mass spectrometry. Rapid Commun Mass Spectrom 2001, 15:2198-2205.
16. Trinh M.U., Blake J., Harrison J.R., Gerace P., Ranieri E., Janice M., Fletcher J.M., Johnson D.W. Quantification of glutamine in dried blood spots and plasma by tandem mass spectrometry for the biochemical diagnosis and monitoring of ornithine transcarbamylase deficiency. Clin Chem. 2003, 49:681-684.
17. Allard P., Grenier A., Korson M.S., Zytkovicz T.H. Newborn screening for hepatorenal tyrosinemia by tandem mass spectrometry: analysis of succinylacetone extracted from dried blood spots. Clin Biochem. 2004, 37:1010-1015.
18. Turgeon C., Magera M.J., Allard P., Tortorelli S., Gavrilov D., Oglesbee D., Raymond K., Rinaldo P., Matern D. Combined newborn screening for succinylacetone, amino acids, and acylcarnitines in dried blood spots. Clin Chem. 2008, 54:657-664.
19. Zhang X.K., Elbin C.S., Chuang W.L., Cooper S.K., Marashio C.A., Beauregard C., Keutzer J.M. Multiplex enzyme assay screening of dried blood spots for lysosomal storage disorders by using tandem mass spectrometry. Clin Chem. 2008, 54:1725-1728.
20. La Marca G., Malvagia S., Pasquini E., Innocenti M., Maria A., Donati M.A., Zammarchi E. Rapid 2nd-tier test for measurement of 3-oh-propionic and methylmalonic acids on dried blood spots: reducing the false-positive rate for propionylcarnitine during expanded newborn screening by liquid chromatography-tandem mass spectrometry. Clin Chem. 2007, 53:1364-1369.
21. Dietzen D.J., Rinaldo P., Whitley R.J., Rhead W.J., Hannon W.H., Garg U.C., Lo S.F., Bennett National M.J. Academy of clinical biochemistry laboratory medicine practice guidelines: follow-up testing for metabolic disease identified by expanded newborn screening using tandem mass spectrometry; executive summar. Clin Chem. 2009, 55:1615-1626.
22. Chace D.H., Singleton S., Diperna J., Aiello M., Foley T. Rapid metabolic and newborn screening of thyroxine (T4) from dried blood spots by MS/MS. Clin Chim Acta. 2009, 403:178-183.
23. Davison A.S., Green B.N., Roberts N.B. Fetal hemoglobin: assessment of glycation and acetylation status by electrospray ionization mass spectrometry. Clin Chem Lab Med. 2008, 46:1230-1238.
24. Buxton O.M., Malarick K., Wang W., Seeman T. Changes in dried blood Spot Hb A1c with varied postcollection conditions. Clin Chem. 2009, 55:1034-1036.
25. Boemer F., Ketelslegers O., Minon J.M., Bours V., Schoos R. Newborn screening for sickle cell disease using tandem mass spectrometry. Clin Chem 2008, 54:2036-2041.
26. Daniel Y.A., Turner C., Haynes R.M., Hunt B.J., Dalton R.N. Rapid and specific detection of clinically significant haemoglobinopathies using electrospray mass spectrometry-mass spectrometry. Br J Haematol 2005, 130:635-643.
27. 2 by tandem mass spectrometry. Clin Chem 2007, 53:1448-1454.
28. Daniel Y.A., Turner C., Farrar L., Dalton R.N. A comparison of IEF and MSMS for clinical hemoglobinopathy screening in 40,000 newborns. From: 50th American Society of Hematology annual meeting 2008, Dec 6-Dec 9. San Francisco.
29. deWilde A., Sadilkova K., Sadilek M., Vasta V., Houn Hahn S. Tryptic peptide analysis of ceruloplasmin in dried blood spots using liquid chromatography-tandem mass spectrometry: application to newborn screening. Clin. Chem. 2008, 54:1961-1968.
30. Chien-Chen L., Chang-Hai T., Fuu-Jen T., Jer-Yuarn W., Wei-De L., Cheng-Chun L. Monitoring of congenital adrenal hyperplasia by microbore HPLC-electrospray ionization tandem mass spectrometry of dried blood spots. Clin Chem. 2002, 48:354-356.
31. Lacey J.M., Minutti C.Z., Magera M.J., Tauscher A.L., Casetta B., McCann M., Lymp J., Houn Hahn S., Rinaldo P., Matern D. Improved specificity of newborn screening for congenital adrenal hyperplasia by second-tier steroid profiling using tandem mass spectrometry. Clin Chem. 2004, 50:621-625.
32. Janzen Test N. Newborn Screening for Congenital Adrenal Hyperplasia: Additional Steroid Profile using Liquid Chromatography-Tandem Mass Spectrometry. J Clinical Endocrinology &Metabolism 2007, 92:2581-2589.
33. Newman M.S., Brandon T.R., Groves M.N., Gregory W.L., Kapur S., Zava D.T. A liquid chromatography/tandem mass spectrometry method for determination of 25-hydroxy vitamin D2 and 25-hydroxy vitamin D3 in dried blood spots: a potential adjunct to diabetes and cardiometabolic risk screening. J Diabetes Sci Technol 2009, 3:156-162.
34. Eyles D., Anderson C., Ko P., Jones A., Thomas A., Burne T., Mortensen P.B., Nørgaard-Pedersen B., Hougaard D.M., McGrath J. A sensitive LC/MS/MS assay of 25OH vitamin D3 and 25OH vitamin D2 in dried blood spots. Clin Chim Acta. 2009, 403:145-151.
35. Eyles D.W., Morley R., Anderson C., Ko P., Burne T., Permezel M., et al. The utility of neonatal dried blood spots for the assessment of neonatal vitamin D status. Paediatr Perinat Epidemiol 2010, 24:303-308.
36. Mushtaq I., Logan S., Morris M., Johnson A.W., Wade A.M., Kelly D. Screening of newborn infants for cholestatic hepatobiliary disease with tandem mass spectrometry BMJ. 1999, 319:471-477.
37. Wilhelm A.J., den Burger J.C., Vos R.M., Chahbouni A., Sinjewel A. Analysis of cyclosporin A in dried blood spots using liquid chromatography tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2009, 877:1595-1598.
38. Hoogtanders K., van der Heijden J., Christiaans M., Edelbroek P., van Hooff J.P., Stolk L.M. Therapeutic drug monitoring of tacrolimus with the dried blood spot method. J Pharm Biomed Anal. 2007, 44:658-664.
39. Cheung C.Y., van der Heijden J., Hoogtanders K., Christiaans M., Liu Y.L., Chan Y.H., et al. Dried blood spot measurement: application in tacrolimus monitoring using limited sampling strategy and abbreviated AUC estimation. Transpl Int. 2008, 21:140-145.
40. van der Heijden J., de Beer Y., Hoogtanders K., Christiaans M., de Jong G.J., Neef C., et al. Therapeutic drug monitoring of everolimus using the dried blood spot method in combination with liquid chromatography-mass spectrometry. J Pharm Biomed Anal 2009, 50:664-670.
41. Alfazil A.A., Anderson R.A. Stability of benzodiazepines and cocaine in blood spots stored on filter paper. J Anal Toxicol. 2008, 32:511-515.
42. la Marca G., Malvagia S., Filippi L., Fiorini P., Innocenti M., Luceri F., Pieraccini G., Moneti G., Francese S., Dani F.R., Guerrini R. Rapid assay of topiramate in dried blood spots by a new liquid chromatography-tandem mass spectrometric method. J Pharm Biomed Anal. 2008, 48:1392-1396.
43. Suyagh M.F., Kole P.L., Millership J., Collier P., Halliday H., McElnay J.C. Development and validation of a dried blood spot-LC-APCI-MS assay for estimation of canrenone in paediatric samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2010, 878:769-776.
44. Mei J.V., Alexander J.R., Adam B.W. Usen of filter paper for the collection and analysis of human whole blood specimens. J.Nutr 2001, 131:1631s-1636s.
45. Adam B.W., Lim T.H., Hall E.M., Hannon W.H. Preliminary proficiency testing results for succinylacetone in dried blood spots for newborn screening for tyrosinemia type I. Clinical Chemistry. 2009, 55:2207-2213.
46. Adam B.W., Alexander J.R., Smith S.J., Chace D.H., Loeber J.G., Elvers L.H., Hannon W.H. Recoveries of phenylalanine from two sets of dried-blood-spot reference materials: prediction from hematocrit, spot volume, and paper matrix. Clin Chem. 2000, 46:126-128.
47. Strnadová K.A., Holub M., Mühl A., Heinze G., Ratschmann R., Mascher H., Stöckler-Ipsiroglu S., Waldhauser F., Votava F., Lebl J., Bodamer O.A. Long-term stability of amino acids and acylcarnitines in dried blood spots. Clin Chem. 2007, 53:717-722.
48. Yates A., Field H., Heynes J., Rainbow S., Bowron A., Calton L., Keevil B. Interlaboratory variation in 25-hydroxyvitamin D2 and 25-hydroxy vitamin D3 is significantly improved if common calibration material is used. Clin Chem. 2008, 54:2082-2084.
49. Carter G.D., Jones J.C. Use of a common standard improves the performance of LC-MS/MS methods for 25-hydroxyvitamin D. Ann Clin Biochem. 2009, 46:79-81.