NCKX5, a natural regulator of human skin colour variation, regulates the expression of key pigment genes MC1R and alpha-MSH and alters cholesterol homeostasis in normal human melanocytes

Advances in Experimental Medicine and Biology

Volumn 961, Issue , 2013, Pages 95-107

  Wilson, Stephen ^a   Ginger, Rebecca S ^a   Dadd, Tony ^a   Gunn, David ^a   Lim, Fei Ling ^a   Sawicka, Magdalena ^a   Sandel, Melanie ^a   Schnetkamp, Paul P M ^b   Green, Martin R ^a  

^a UNILEVER RESEARCH   (United Kingdom)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

Cholesterol; Melanocyte; Pigmentation; trans Golgi

Indexed keywords

ALANINE; ALPHA INTERMEDIN; CALCIUM; CHOLESTEROL; MELANOCORTIN 1 RECEPTOR; POTASSIUM; PROTEIN NCKX5; PROTEIN VARIANT; REGULATOR PROTEIN; SMALL INTERFERING RNA; SODIUM; SODIUM CALCIUM EXCHANGE PROTEIN; STEROL; THREONINE; UNCLASSIFIED DRUG;

ALPHA MSH GENE; AMINO ACID SUBSTITUTION; ASIAN; CELL LEVEL; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; CONFERENCE PAPER; ENDOPLASMIC RETICULUM; GENE; GENE EXPRESSION REGULATION; GENE NUMBER; GENE SILENCING; GENETIC ASSOCIATION; GENETIC VARIABILITY; GOLGI COMPLEX; HUMAN; MC1R GENE; MELANOCYTE; MELANOGENESIS; MICROARRAY ANALYSIS; NONHUMAN; POLYMERASE CHAIN REACTION; POPULATION GENETICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; RADIATION EXPOSURE; REGULATOR GENE; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN COLOR; SKIN PIGMENTATION; SLC24A5 GENE; ULTRAVIOLET RADIATION;

EID: 84873572883     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4614-4756-6_9     Document Type: Conference Paper

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