The lipid kinase PI4KIIIβ preserves lysosomal identity

EMBO Journal

Volumn 32, Issue 3, 2013, Pages 324-339

  Sridhar, Sunandini ^a   Patel, Bindi ^a   Aphkhazava, David ^b   Macian, Fernando ^a,b   Santambrogio, Laura ^a,b   Shields, Dennis ^a   Cuervo, Ana Maria ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b Department of Pathology ^*  (United States)

Author keywords

Autophagy; Lipid kinase; Lysosome membrane; Vesicular trafficking

Indexed keywords

PHOSPHATIDYLINOSITOL 4 KINASE III BETA; PHOSPHATIDYLINOSITOL KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL LOSS; CELL MIGRATION; CELL SELECTION; CELL STRUCTURE; CELL SURFACE; CONTROLLED STUDY; ENZYME ACTIVITY; LYSOSOME; LYSOSOME STRUCTURE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM;

1-PHOSPHATIDYLINOSITOL 4-KINASE; ANIMALS; BIOLOGICAL TRANSPORT; CERCOPITHECUS AETHIOPS; COS CELLS; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; LENTIVIRUS; LIPID METABOLISM; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 1; LYSOSOMES; MALE; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; NIH 3T3 CELLS; PROTEIN ISOFORMS; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING;

EID: 84873569950     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.341     Document Type: Article

References (38)

1. Andrews NW (2000) Regulated secretion of conventional lysosomes. Trends Cell Biol 10: 316-321 (Pubitemid 30445238)
2. Aniento F, Emans N, Griffiths G, Gruenberg J (1993) Cytoplasmic dynein-dependent vesicular transport from early to late endosomes. J Cell Biol 123: 1373-1387 (Pubitemid 24012018)
3. Balla A, Balla T (2006) Phosphatidylinositol 4-kinases: Old enzymes with emerging functions. Trends Cell Biol 16: 351-361 (Pubitemid 44062315)
4. Bandyopadhyay U, Sridhar S, Kaushik S, Kiffin R, Cuervo AM (2010) Identification of regulators of chaperone-nediated autophagy. Mol Cell 39: 535-547
5. Blagoveshchenskaya A, Cheong FY, Rohde HM, Glover G, Knodler A, Nicolson T, Boehmelt G, Mayinger P (2008) Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1. J Cell Biol 180: 803-812 (Pubitemid 351397779)
6. Boes M, Cerny J, Massol R, Op den Brouw M, Kirchhausen T, Chen J, Ploegh HL (2002) T-cell engagement of dendritic cells rapidly rearranges MHC class II transport. Nature 418: 983-988 (Pubitemid 34976034)
7. Bonifacino JS, Hurley JH (2008) Retromer. Curr Opin Cell Biol 20: 427-436
8. Bright NA, Gratian MJ, Luzio JP (2005) Endocytic delivery to lysosomes mediated by concurrent fusion and kissing events in living cells. Curr Biol 15: 360-365 (Pubitemid 40263370)
9. Carlton JG, Cullen PJ (2005) Coincidence detection in phosphoinositide signaling. Trends Cell Biol 15: 540-547 (Pubitemid 41398187)
10. Chow A, Toomre D, Garrett W, Mellman I (2002) Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane. Nature 418: 988-994 (Pubitemid 34976035)
11. Cuervo AM, Dice JF, Knecht E (1997) A population of rat liver lysosomes responsible for the selective uptake and degradation of cytosolic proteins. J Biol Chem 272: 5606-5615 (Pubitemid 27102386)
12. Cullen PJ, Carlton JG (2012) Phosphoinositides in the mammalian endo-lysosomal network. Subcell Biochem 59: 65-110
13. D'Angelo G, Vicinanza M, Wilson C, De Matteis MA (2012) Phosphoinositides in Golgi complex function. Subcell Biochem 59: 255-270
14. de Barry J, Janoshazi A, Dupont JL, Procksch O, Chasserot-Golaz S, Jeromin A, Vitale N (2006) Functional implication of neuronal calcium sensor-1 and phosphoinositol 4-kinase-beta interaction in regulated exocytosis of PC12 cells. J Biol Chem 281: 18098-18111 (Pubitemid 44035610)
15. Faulhammer F, Kanjilal-Kolar S, Knodler A, Lo J, Lee Y, Konrad G, Mayinger P (2007) Growth control of Golgi phosphoinositides by reciprocal localization of sac1 lipid phosphatase and pik1 -kinase. Traffic 8: 1554-1567 (Pubitemid 47578361)
16. Godi A, Di Campli A, Konstantakopoulos A, Di Tullio G, Alessi DR, Kular GS, Daniele T, Marra P, Lucocq JM, De Matteis MA (2004) FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P. Nat Cell Biol 6: 393-404 (Pubitemid 38607499)
17. Godi A, Pertile P, Meyers R, Marra P, Di Tullio G, Iurisci C, Luini A, Corda D, De Matteis MA (1999a) ARF mediates recruitment of PtdIns-4-OH kinase-beta and stimulates synthesis of PtdIns(4,5)P2 on the Golgi complex. Mol Biol Cell 1: 280-287 (Pubitemid 129495778)
18. Godi A, Pertile P, Meyers R, Marra P, Di Tullio G, Iurisci C, Luini A, Corda D, De Matteis MA (1999b) ARF mediates recruitment of PtdIns-4-OH kinase-beta and stimulates synthesis of PtdIns(4,5)P2 on the Golgi complex. Nat Cell Biol 1: 280-287 (Pubitemid 129495778)
19. Jovic M, Kean MJ, Szentpetery Z, Polevoy G, Gingras AC, Brill JA, Balla T (2012) Two phosphatidylinositol 4-kinases control lysosomal delivery of the Gaucher disease enzyme, beta-glucocerebrosidase. Mol Biol Cell 23: 1533-1545
20. Kiffin R, Kaushik S, Zeng M, Bandyopadhyay U, Zhang C, Massey AC, Martinez-Vicente M, Cuervo AM (2007) Altered dynamics of the lysosomal receptor for chaperone-mediated autophagy with age. J Cell Sci 120: 782-791 (Pubitemid 46523480)
21. Kimura S, Noda T, Yoshimori T (2007) Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy 3: 452-460 (Pubitemid 47293726)
22. Koga H, Kaushik S, Cuervo AM (2010) Inhibitory effect of intracellular lipid load on macroautophagy. Autophagy 6: 825-827
23. Lange Y, Ye J, Steck TL (2012) Activation mobilizes the cholesterol in the late endosomes-lysosomes of Niemann Pick type C cells. PLoS ONE 7: E30051
24. Marzella L, Ahlberg J, Glaumann H (1982) Isolation of autophagic vacuoles from rat liver: Morphological and biochemical characterization. J Cell Biol 93: 144-154 (Pubitemid 12117051)
25. Miller SE, Collins BM, McCoy AJ, Robinson MS, Owen DJ (2007) A SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles. Nature 450: 570-574 (Pubitemid 350190254)
26. Minogue S, Waugh MG (2012) The Phosphatidylinositol 4-Kinases: Don't Call it a Comeback. Subcell Biochem 58: 1-24
27. Polevoy G, Wei HC, Wong R, Szentpetery Z, Kim YJ, Goldbach P, Steinbach SK, Balla T, Brill JA (2009) Dual roles for the Drosophila PI 4-kinase four wheel drive in localizing Rab11 during cytokinesis. J Cell Biol 187: 847-858
28. Rodriguez-Navarro JA, Kaushik S, Koga H, Dall'Armi C, Shui G, Wenk MR, Di Paolo G, Cuervo AM (2012) Inhibitory effect of dietary lipids on chaperone-mediated autophagy. Proc Natl Acad Sci USA 109: E705-E714
29. Rong Y, Liu M, Ma L, Du W, Zhang H, Tian Y, Cao Z, Li Y, Ren H, Zhang C, Li L, Chen S, Xi J, Yu L (2012) Clathrin and phosphatidylinositol- 4,5-bisphosphate regulate autophagic lysosome reformation. Nat Cell Biol 14: 924-934
30. Saftig P, Klumperman J (2009) Lysosome biogenesis and lysosomal membrane proteins: Trafficking meets function. Nat Rev Mol Cell Biol 10: 623-635
31. Saksena S, Sun J, Chu T, Emr SD (2007) ESCRTing proteins in the endocytic pathway. Trends Biochem Sci 32: 561-573 (Pubitemid 350123053)
32. Salazar G, Zlatic S, Craige B, Peden AA, Pohl J, Faundez V (2009) Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and nonneuronal cells. J Biol Chem 284: 1790-1802
33. Storrie B, Madden E (1990) Isolation of subcellular organelles. Methods Enzymol 182: 203-225 (Pubitemid 20154389)
34. Sweeney DA, Siddhanta A, Shields D (2002) Fragmentation and reassembly of the Golgi apparatus in vitro. A requirement for phosphatidic acid and phosphatidylinositol 4,5-bisphosphate synthesis. J Biol Chem 277: 3030-3039 (Pubitemid 34953340)
35. Szentpetery Z, Varnai P, Balla T (2010) Acute manipulation of Golgi phosphoinositides to assess their importance in cellular trafficking and signaling. Proc Natl Acad Sci USA 107: 8225-8230
36. Wieffer M, Haucke V, Krauss M (2012) Regulation of phosphoinositide- metabolizing enzymes by clathrin coat proteins. Methods Cell Biol 108: 209-225
37. Yang N, Ma P, Lang J, Zhang Y, Deng J, Ju X, Zhang G, Jiang C (2012) Phosphatidylinositol 4-kinase IIIbeta is required for severe acute respiratory syndrome coronavirus spike-mediated cell entry. J Biol Chem 287: 8457-8467
38. Yu L, McPhee CK, Zheng L, Mardones GA, Rong Y, Peng J, Mi N, Zhao Y, Liu Z, Wan F, Hailey DW, Oorschot V, Klumperman J, Baehrecke EH, Lenardo MJ (2010) Termination of autophagy and reformation of lysosomes regulated by mTOR. Nature 465: 942-946