Two phosphatidylinositol 4-kinases control lysosomal delivery of the Gaucher disease enzyme, β-glucocerebrosidase

Molecular Biology of the Cell

Volumn 23, Issue 8, 2012, Pages 1533-1545

  Jović, Marko ^a   Kean, Michelle J ^b,c   Szentpetery, Zsofia ^a   Polevoy, Gordon ^d   Gingras, Anne Claude ^b,c   Brill, Julie A ^c,d   Balla, Tamas ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b MOUNT SINAI HOSPITAL   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSYLCERAMIDASE; LYSOSOMAL INTEGRAL MEMBRANE PROTEIN TYPE 2; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL 4 PHOSPHATE; PHOSPHATIDYLINOSITOL KINASE; PHOSPHATIDYLINOSITOL KINASE 2 ALPHA; PHOSPHATIDYLINOSITOL KINASE 3 BETA; RAPAMYCIN; SPHINGOLIPID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL COMPARTMENTALIZATION; CELL MIGRATION; CELL VACUOLE; CONTROLLED STUDY; ENDOSOME; GAUCHER DISEASE; GOLGI COMPLEX; HOMEOSTASIS; HUMAN; HUMAN CELL; LYSOSOME; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

1-PHOSPHATIDYLINOSITOL 4-KINASE; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; ENDOSOMES; GAUCHER DISEASE; GLUCOSYLCERAMIDASE; GOLGI APPARATUS; HEK293 CELLS; HUMANS; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 2; LYSOSOMES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN TRANSPORT; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84859710023     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E11-06-0553     Document Type: Article

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