Guided bone regeneration using injectable vascular endothelial growth factor delivery gel

Journal of Periodontology

Volumn 84, Issue 2, 2013, Pages 230-238

  Kaigler, Darnell ^a   Silva, Eduardo A ^b   Mooney, David J ^b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

Angiogenesis inducing agents; Bioengineering; Bone and bones; Endothelial growth factors; Hydrogel; Regenerative medicine

Indexed keywords

ALGINIC ACID; COLLAGEN; RECOMBINANT PROTEIN; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ANGIOGENESIS; ANIMAL; ARTICLE; ARTIFICIAL MEMBRANE; BLOOD VESSEL; BONE DEVELOPMENT; BONE DISEASE; BONE REGENERATION; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG DELIVERY SYSTEM; DRUG EFFECT; FISCHER 344 RAT; HYDROGEL; IMAGE PROCESSING; INJECTION; METHODOLOGY; MICRO-COMPUTED TOMOGRAPHY; PATHOLOGY; RAT; SKULL; THREE DIMENSIONAL IMAGING; TIME; TISSUE REGENERATION;

ALGINATES; ANIMALS; BLOOD VESSELS; BONE DISEASES; BONE REGENERATION; COLLAGEN; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; GUIDED TISSUE REGENERATION; HYDROGELS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; INJECTIONS; MEMBRANES, ARTIFICIAL; NEOVASCULARIZATION, PHYSIOLOGIC; OSTEOGENESIS; RATS; RATS, INBRED F344; RECOMBINANT PROTEINS; SKULL; TIME FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; X-RAY MICROTOMOGRAPHY;

EID: 84873549333     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2012.110684     Document Type: Article

References (42)

1. Darby I, Chen ST, Buser D. Ridge preservation techniques for implant therapy. Int J Oral Maxillofac Implants 2009;24(Suppl.):260-271.
2. Fiorellini JP, Nevins ML. Localized ridge augmentation/preservation. A systematic review. Ann Periodontol 2003;8:321-327.
3. Esposito M, Grusovin MG, Felice P, Karatzopoulos G, Worthington HV, Coulthard P. Interventions for replacing missing teeth: Horizontal and vertical bone augmentation techniques for dental implant treatment. Cochrane Database Syst Rev 2009;(4):CD003607.
4. Jensen SS, Terheyden H. Bone augmentation procedures in localized defects in the alveolar ridge: Clinical results with different bone grafts and bonesubstitute materials. Int J Oral Maxillofac Implants 2009;24(Suppl.):218- 236.
5. Margonar R, dos Santos PL, Queiroz TP, Marcantonio E. Rehabilitation of atrophic maxilla using the combination of autogenous and allogeneic bone grafts followed by protocol-type prosthesis. J Craniofac Surg 2010;21:1894-1896.
6. Chiapasco M, Zaniboni M. Failures in jaw reconstructive surgery with autogenous onlay bone grafts for pre-implant purposes: Incidence, prevention and management of complications. Oral Maxillofac Surg Clin North Am 2011;23:1-15, v.
7. Sculean A, Nikolidakis D, Schwarz F. Regeneration of periodontal tissues: Combinations of barrier membranes and grafting materials -Biological foundation and preclinical evidence: A systematic review. J Clin Periodontol 2008;35(Suppl. 8):106-116.
8. Wang HL, Boyapati L. "PASS" principles for predictable bone regeneration. Implant Dent 2006;15:8-17.
9. Chiapasco M, Casentini P, Zaniboni M. Bone augmentation procedures in implant dentistry. Int J Oral Maxillofac Implants 2009;24(Suppl.):237-259.
10. Melcher AH. On the repair potential of periodontal tissues. J Periodontol 1976;47:256-260.
11. Retzepi M, Donos N. Guided bone regeneration: Biological principle and therapeutic applications. Clin Oral Implants Res 2010;21:567-576.
12. McAllister BS, Haghighat K. Bone augmentation techniques. J Periodontol 2007;78:377-396.
13. Schwarz F, Ferrari D, Sager M, Herten M, Hartig B, Becker J. Guided bone regeneration using rhGDF-5- and rhBMP-2-coated natural bone mineral in rat calvarial defects. Clin Oral Implants Res 2009;20:1219-1230.
14. Simion M, Rocchietta I, Kim D, Nevins M, Fiorellini J. Vertical ridge augmentation by means of deproteinized bovine bone block and recombinant human plateletderived growth factor-BB: A histologic study in a dog model. Int J Periodontics Restorative Dent 2006;26: 415-423.
15. Stephan EB, Renjen R, Lynch SE, Dziak R. Plateletderived growth factor enhancement of a mineral-collagen bone substitute. J Periodontol 2000;71:1887-1892.
16. Nevins M, Giannobile WV, McGuire MK, et al. Plateletderived growth factor stimulates bone fill and rate of attachment level gain: Results of a large multicenter randomized controlled trial. J Periodontol 2005;76: 2205-2215.
17. Camelo M, Nevins ML, Schenk RK, Lynch SE, Nevins M. Periodontal regeneration in human Class II furcations using purified recombinant human platelet-derived growth factor-BB (rhPDGF-BB) with bone allograft. Int J Periodontics Restorative Dent 2003;23:213-225.
18. Hollinger JO, Hart CE, Hirsch SN, Lynch S, Friedlaender GE. Recombinant human platelet-derived growth factor: Biology and clinical applications. J Bone Joint Surg Am 2008;90(Suppl. 1):48-54.
19. Kaigler D, Avila G, Wisner-Lynch L, et al. Plateletderived growth factor applications in periodontal and peri-implant bone regeneration. Expert Opin Biol Ther 2011;11:375-385.
20. Lee KY, Peters MC, Anderson KW, Mooney DJ. Controlled growth factor release from synthetic extracellular matrices. Nature 2000;408:998-1000.
21. Boontheekul T, Kong HJ, Mooney DJ. Controlling alginate gel degradation utilizing partial oxidation and bimodal molecular weight distribution. Biomaterials 2005;26:2455-2465.
22. Ferrara N. Binding to the extracellular matrix and proteolytic processing: Two key mechanisms regulating vascular endothelial growth factor action. Mol Biol Cell 2010;21:687-690.
23. Schwarz F, Rothamel D, Herten M, et al. Immunohistochemical characterization of guided bone regeneration at a dehiscence-type defect using different barrier membranes: An experimental study in dogs. Clin Oral Implants Res 2008;19:402-415.
24. Ivanovski S, Hamlet S, Retzepi M, Wall I, Donos N. Transcriptional profiling of "guided bone regeneration" in a critical-size calvarial defect. Clin Oral Implants Res 2011;22:382-389.
25. Borselli C, Storrie H, Benesch-Lee F, et al. Functional muscle regeneration with combined delivery of angiogenesis and myogenesis factors. Proc Natl Acad Sci USA 2010;107:3287-3292.
26. Yuen WW, Du NR, Chan CH, Silva EA, Mooney DJ. Mimicking nature by codelivery of stimulant and inhibitor to create temporally stable and spatially restricted angiogenic zones. Proc Natl Acad Sci USA 2010;107:17933-17938.
27. Silva EA, Mooney DJ. Effects of VEGF temporal and spatial presentation on angiogenesis. Biomaterials 2010;31:1235-1241.
28. Chen RR, Silva EA, Yuen WW, et al. Integrated approach to designing growth factor delivery systems. FASEB J 2007;21:3896-3903.
29. Silva EA, Mooney DJ. Spatiotemporal control of vascular endothelial growth factor delivery from injectable hydrogels enhances angiogenesis. J Thromb Haemost 2007;5:590-598.
30. Schmitz JP, Hollinger JO. The critical size defect as an experimental model for craniomandibulofacial nonunions. Clin Orthop Relat Res 1986;(205):299-308.
31. Kong HJ, Kaigler D, Kim K, Mooney DJ. Controlling rigidity and degradation of alginate hydrogels via molecular weight distribution. Biomacromolecules 2004;5:1720-1727.
32. Kaigler D, Wang Z, Horger K, Mooney DJ, Krebsbach PH. VEGF scaffolds enhance angiogenesis and bone regeneration in irradiated osseous defects. J Bone Miner Res 2006;21:735-744.
33. Kaigler D, Krebsbach PH, West ER, Horger K, Huang YC, Mooney DJ. Endothelial cell modulation of bone marrow stromal cell osteogenic potential. FASEB J 2005;19:665-667.
34. Emerich DF, Silva E, Ali O, et al. Injectable VEGF hydrogels produce near complete neurological and anatomical protection following cerebral ischemia in rats. Cell Transplant 2010;19:1063-1071.
35. Hao X, Silva EA, Månsson-Broberg A, et al. Angiogenic effects of sequential release of VEGF-A165 and PDGFBB with alginate hydrogels after myocardial infarction. Cardiovasc Res 2007;75:178-185.
36. Yonamine Y, Matsuyama T, Sonomura T, et al. Effectable application of vascular endothelial growth factor to critical sized rat calvaria defects. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010;109: 225-231.
37. Leach JK, Kaigler D, Wang Z, Krebsbach PH, Mooney DJ. Coating of VEGF-releasing scaffolds with bioactive glass for angiogenesis and bone regeneration. Biomaterials 2006;27:3249-3255.
38. Patel ZS, Young S, Tabata Y, Jansen JA, Wong ME, Mikos AG. Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model. Bone 2008;43:931-940.
39. Cao L, Arany PR, Wang YS, Mooney DJ. Promoting angiogenesis via manipulation of VEGF responsiveness with notch signaling. Biomaterials 2009;30:4085-4093.
40. Augst AD, Kong HJ, Mooney DJ. Alginate hydrogels as biomaterials. Macromol Biosci 2006;6:623-633.
41. Mayr-Wohlfart U, Waltenberger J, Hausser H, et al. Vascular endothelial growth factor stimulates chemotactic migration of primary human osteoblasts. Bone 2002;30:472-477.
42. Zelzer E, McLean W, Ng YS, et al. Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development 2002;129: 1893-1904.