Mechanisms of penitrem-induced cerebellar granule neuron death in vitro: Possible involvement of GABAA receptors and oxidative processes

NeuroToxicology

Volumn 35, Issue 1, 2013, Pages 129-136

  Berntsen, H F ^a,c   Wigestrand, M B ^a   Bogen, I L ^a   Fonnum, F ^a   Walaas, S I ^a   Moldes Anaya, A ^b  

^a UNIVERSITY OF OSLO   (Norway)

^b NORWEGIAN VETERINARY INSTITUTE   (Norway)

^c NORWEGIAN UNIVERSITY OF LIFE SCIENCES   (Norway)

Author keywords

Cerebellar granule neurons; GABAA receptors; Neurological disorders; Oxidative stress; Penitrem A

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; ALFAXALONE; ALPHA TOCOPHEROL; AMPA RECEPTOR; BICUCULLINE; DIAZEPAM; GLYCINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROTOXIN; PENITREM A; PENTOBARBITAL; PHENOBARBITAL; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; CYTOTOXICITY TEST; DOSE RESPONSE; DRUG EXPOSURE; FEMALE; GABAERGIC SYSTEM; GRANULE CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; MALE; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; ANIMALS, NEWBORN; CALCIUM; CELL DEATH; CELLS, CULTURED; CEREBELLUM; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MYCOTOXINS; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RECEPTORS, GABA-A; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84873543557     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2013.01.004     Document Type: Article

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