Neuroprotection by c-Jun NH2-terminal kinase inhibitor SP600125 against potassium deprivation-induced apoptosis involves the Akt pathway and inhibition of cell cycle reentry

Neuroscience

Volumn 159, Issue 3, 2009, Pages 1135-1147

  Yeste Velasco, M ^a   Folch, J ^b   Casadesus G ^c   Smith, M A ^c   Pallas M ^a   Camins, A ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b FACULTAT DE MEDICINA I CIÈNCIES DE LA SALUT   (Spain)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Akt; c Jun NH2 terminal kinase; cell cycle; cerebellar granule cells; SP600125

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIN DEPENDENT KINASE 5; GLYCOGEN SYNTHASE KINASE 3BETA; POTASSIUM; PROTEIN KINASE B; PROTEIN P25; PROTEIN P35; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR FKHR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE REGULATION; CEREBELLUM; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GRANULE CELL; INHIBITION KINETICS; NEUROPROTECTION; NONHUMAN; POTASSIUM DEFICIENCY; PRIORITY JOURNAL; RAT;

ANIMALS; ANTHRACENES; APOPTOSIS; CELL CYCLE; CELLS, CULTURED; CEREBELLUM; CHROMONES; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIN-DEPENDENT KINASE 5; ENZYME INHIBITORS; FORKHEAD TRANSCRIPTION FACTORS; GLYCOGEN SYNTHASE KINASE 3; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MORPHOLINES; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PHOSPHOTRANSFERASES; POTASSIUM; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 62549119517     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2009.01.035     Document Type: Article

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