메뉴 건너뛰기




Volumn 55, Issue 7, 2009, Pages 581-592

Role of oxidative stress and JNK pathway in apoptotic death induced by potassium deprivation and staurosporine in cerebellar granule neurons

Author keywords

Antioxidants; Apoptosis; Caspase; MAPK; ROS; SP600125

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ANTIOXIDANT; APOPTOSIS SIGNAL REGULATING KINASE 1; CASPASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; POTASSIUM; PROTEIN C JUN; REACTIVE OXYGEN METABOLITE; STAUROSPORINE; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE 1;

EID: 69349098403     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2009.05.015     Document Type: Article
Times cited : (29)

References (77)
  • 1
    • 0038680621 scopus 로고    scopus 로고
    • Mechanisms of cell death by deprivation of depolarizing conditions during cerebellar granule neurons maturation
    • Alavez S., Pedroza D., and Moran J. Mechanisms of cell death by deprivation of depolarizing conditions during cerebellar granule neurons maturation. Neurochem. Int. 43 (2003) 581-590
    • (2003) Neurochem. Int. , vol.43 , pp. 581-590
    • Alavez, S.1    Pedroza, D.2    Moran, J.3
  • 2
    • 5444234359 scopus 로고    scopus 로고
    • Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis
    • Becker E.B., Howell J., Kodama Y., Barker P.A., and Bonni A. Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis. J. Neurosci. 24 (2004) 8762-8770
    • (2004) J. Neurosci. , vol.24 , pp. 8762-8770
    • Becker, E.B.1    Howell, J.2    Kodama, Y.3    Barker, P.A.4    Bonni, A.5
  • 3
    • 0032979438 scopus 로고    scopus 로고
    • Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation
    • Behrens A., Sibilia M., and Wagner E.F. Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation. Nat. Genet. 21 (1999) 326-329
    • (1999) Nat. Genet. , vol.21 , pp. 326-329
    • Behrens, A.1    Sibilia, M.2    Wagner, E.F.3
  • 4
    • 0032921811 scopus 로고    scopus 로고
    • Hydrogen peroxide activation of multiple mitogen-activated protein kinases in an oligodendrocyte cell line: role of extracellular signal-regulated kinase in hydrogen peroxide-induced cell death
    • Bhat N.R., and Zhang P. Hydrogen peroxide activation of multiple mitogen-activated protein kinases in an oligodendrocyte cell line: role of extracellular signal-regulated kinase in hydrogen peroxide-induced cell death. J. Neurochem. 72 (1999) 112-119
    • (1999) J. Neurochem. , vol.72 , pp. 112-119
    • Bhat, N.R.1    Zhang, P.2
  • 5
    • 34247523696 scopus 로고    scopus 로고
    • Pathological apoptosis in the developing brain
    • Blomgren K., Leist M., and Groc L. Pathological apoptosis in the developing brain. Apoptosis 12 (2007) 993-1010
    • (2007) Apoptosis , vol.12 , pp. 993-1010
    • Blomgren, K.1    Leist, M.2    Groc, L.3
  • 6
    • 34547857049 scopus 로고    scopus 로고
    • The functional contrariety of JNK
    • Bode A.M., and Dong Z. The functional contrariety of JNK. Mol. Carcinog. 46 (2007) 591-598
    • (2007) Mol. Carcinog. , vol.46 , pp. 591-598
    • Bode, A.M.1    Dong, Z.2
  • 7
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 8
    • 0034918203 scopus 로고    scopus 로고
    • JNK3 contributes to c-Jun activation and apoptosis but not oxidative stress in nerve growth factor-deprived sympathetic neurons
    • Bruckner S.R., Tammariello S.P., Kuan C.Y., Flavell R.A., Rakic P., and Estus S. JNK3 contributes to c-Jun activation and apoptosis but not oxidative stress in nerve growth factor-deprived sympathetic neurons. J. Neurochem. 78 (2001) 298-303
    • (2001) J. Neurochem. , vol.78 , pp. 298-303
    • Bruckner, S.R.1    Tammariello, S.P.2    Kuan, C.Y.3    Flavell, R.A.4    Rakic, P.5    Estus, S.6
  • 10
    • 0037308354 scopus 로고    scopus 로고
    • Caspase activation pathways induced by staurosporine and low potassium: role of caspase-2
    • Caballero-Benitez A., and Moran J. Caspase activation pathways induced by staurosporine and low potassium: role of caspase-2. J. Neurosci. Res. 71 (2003) 383-396
    • (2003) J. Neurosci. Res. , vol.71 , pp. 383-396
    • Caballero-Benitez, A.1    Moran, J.2
  • 11
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • Chang L., and Karin M. Mammalian MAP kinase signalling cascades. Nature 410 (2001) 37-40
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 12
    • 2442502511 scopus 로고    scopus 로고
    • Phosphorylation of p38 MAPK induced by oxidative stress is linked to activation of both caspase-8- and -9-mediated apoptotic pathways in dopaminergic neurons
    • Choi W.S., Eom D.S., Han B.S., Kim W.K., Han B.H., Choi E.J., Oh T.H., Markelonis G.J., Cho J.W., and Oh Y.J. Phosphorylation of p38 MAPK induced by oxidative stress is linked to activation of both caspase-8- and -9-mediated apoptotic pathways in dopaminergic neurons. J. Biol. Chem. 279 (2004) 20451-20460
    • (2004) J. Biol. Chem. , vol.279 , pp. 20451-20460
    • Choi, W.S.1    Eom, D.S.2    Han, B.S.3    Kim, W.K.4    Han, B.H.5    Choi, E.J.6    Oh, T.H.7    Markelonis, G.J.8    Cho, J.W.9    Oh, Y.J.10
  • 13
    • 33947203625 scopus 로고    scopus 로고
    • Differential regulation of inhibitors of apoptosis proteins in Alzheimer's disease brains
    • Christie L.A., Su J.H., Tu C.H., Dick M.C., Zhou J., and Cotman C.W. Differential regulation of inhibitors of apoptosis proteins in Alzheimer's disease brains. Neurobiol. Dis. 26 (2007) 165-173
    • (2007) Neurobiol. Dis. , vol.26 , pp. 165-173
    • Christie, L.A.1    Su, J.H.2    Tu, C.H.3    Dick, M.C.4    Zhou, J.5    Cotman, C.W.6
  • 14
    • 0036615741 scopus 로고    scopus 로고
    • c-Jun N-terminal protein kinase (JNK) 2/3 is specifically activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons
    • Coffey E.T., Smiciene G., Hongisto V., Cao J., Brecht S., Herdegen T., and Courtney M.J. c-Jun N-terminal protein kinase (JNK) 2/3 is specifically activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons. J. Neurosci. 22 (2002) 4335-4345
    • (2002) J. Neurosci. , vol.22 , pp. 4335-4345
    • Coffey, E.T.1    Smiciene, G.2    Hongisto, V.3    Cao, J.4    Brecht, S.5    Herdegen, T.6    Courtney, M.J.7
  • 15
    • 53049091077 scopus 로고    scopus 로고
    • Role of NADPH oxidase in the apoptotic death of cultured cerebellar granule neurons
    • Coyoy A., Valencia A., Guemez-Gamboa A., and Moran J. Role of NADPH oxidase in the apoptotic death of cultured cerebellar granule neurons. Free Radic. Biol. Med. 45 (2008) 1056-1064
    • (2008) Free Radic. Biol. Med. , vol.45 , pp. 1056-1064
    • Coyoy, A.1    Valencia, A.2    Guemez-Gamboa, A.3    Moran, J.4
  • 16
    • 29144526703 scopus 로고    scopus 로고
    • Apaf1 mediates apoptosis and mitochondrial damage induced by mutant human SOD1s typical of familial amyotrophic lateral sclerosis
    • Cozzolino M., Ferri A., Ferraro E., Rotilio G., Cecconi F., and Carri M.T. Apaf1 mediates apoptosis and mitochondrial damage induced by mutant human SOD1s typical of familial amyotrophic lateral sclerosis. Neurobiol. Dis. 21 (2006) 69-79
    • (2006) Neurobiol. Dis. , vol.21 , pp. 69-79
    • Cozzolino, M.1    Ferri, A.2    Ferraro, E.3    Rotilio, G.4    Cecconi, F.5    Carri, M.T.6
  • 17
    • 0031054670 scopus 로고    scopus 로고
    • Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling
    • D'Mello S.R., Borodezt K., and Soltoff S.P. Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling. J. Neurosci. 17 (1997) 1548-1560
    • (1997) J. Neurosci. , vol.17 , pp. 1548-1560
    • D'Mello, S.R.1    Borodezt, K.2    Soltoff, S.P.3
  • 18
    • 0027483920 scopus 로고
    • Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP
    • D'Mello S.R., Galli C., Ciotti T., and Calissano P. Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 10989-10993
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 10989-10993
    • D'Mello, S.R.1    Galli, C.2    Ciotti, T.3    Calissano, P.4
  • 19
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • Davis R.J. Signal transduction by the JNK group of MAP kinases. Cell 103 (2000) 239-252
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 22
    • 0023244774 scopus 로고
    • The role of depolarization in the survival and differentiation of cerebellar granule cells in culture
    • Gallo V., Kingsbury A., Balazs R., and Jorgensen O.S. The role of depolarization in the survival and differentiation of cerebellar granule cells in culture. J. Neurosci. 7 (1987) 2203-2213
    • (1987) J. Neurosci. , vol.7 , pp. 2203-2213
    • Gallo, V.1    Kingsbury, A.2    Balazs, R.3    Jorgensen, O.S.4
  • 23
    • 0344012006 scopus 로고    scopus 로고
    • Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis
    • Gil J., Almeida S., Oliveira C.R., and Rego A.C. Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis. Free Radic. Biol. Med. 35 (2003) 1500-1514
    • (2003) Free Radic. Biol. Med. , vol.35 , pp. 1500-1514
    • Gil, J.1    Almeida, S.2    Oliveira, C.R.3    Rego, A.C.4
  • 24
    • 1642410790 scopus 로고    scopus 로고
    • Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation
    • Goldman E.H., Chen L., and Fu H. Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation. J. Biol. Chem. 279 (2004) 10442-10449
    • (2004) J. Biol. Chem. , vol.279 , pp. 10442-10449
    • Goldman, E.H.1    Chen, L.2    Fu, H.3
  • 25
    • 0032504189 scopus 로고    scopus 로고
    • Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction
    • Gotoh Y., and Cooper J.A. Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction. J. Biol. Chem. 273 (1998) 17477-17482
    • (1998) J. Biol. Chem. , vol.273 , pp. 17477-17482
    • Gotoh, Y.1    Cooper, J.A.2
  • 26
    • 0028893492 scopus 로고
    • Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death
    • Greenlund L.J., Deckwerth T.L., and Johnson Jr. E.M. Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death. Neuron 14 (1995) 303-315
    • (1995) Neuron , vol.14 , pp. 303-315
    • Greenlund, L.J.1    Deckwerth, T.L.2    Johnson Jr., E.M.3
  • 27
    • 0032919249 scopus 로고    scopus 로고
    • An inhibitor of p38 and JNK MAP kinases prevents activation of caspase and apoptosis of cultured cerebellar granule neurons
    • Harada J., and Sugimoto M. An inhibitor of p38 and JNK MAP kinases prevents activation of caspase and apoptosis of cultured cerebellar granule neurons. Jpn. J. Pharmacol. 79 (1999) 369-378
    • (1999) Jpn. J. Pharmacol. , vol.79 , pp. 369-378
    • Harada, J.1    Sugimoto, M.2
  • 28
    • 0036845266 scopus 로고    scopus 로고
    • Identification of JNK-dependent and -independent components of cerebellar granule neuron apoptosis
    • Harris C., Maroney A.C., and Johnson Jr. E.M. Identification of JNK-dependent and -independent components of cerebellar granule neuron apoptosis. J. Neurochem. 83 (2002) 992-1001
    • (2002) J. Neurochem. , vol.83 , pp. 992-1001
    • Harris, C.1    Maroney, A.C.2    Johnson Jr., E.M.3
  • 29
    • 0033554554 scopus 로고    scopus 로고
    • Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1)
    • Hoeflich K.P., Yeh W.C., Yao Z., Mak T.W., and Woodgett J.R. Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1). Oncogene 18 (1999) 5814-5820
    • (1999) Oncogene , vol.18 , pp. 5814-5820
    • Hoeflich, K.P.1    Yeh, W.C.2    Yao, Z.3    Mak, T.W.4    Woodgett, J.R.5
  • 30
    • 0029982565 scopus 로고    scopus 로고
    • Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)
    • Jiang Y., Chen C., Li Z., Guo W., Gegner J.A., Lin S., and Han J. Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta). J. Biol. Chem. 271 (1996) 17920-17926
    • (1996) J. Biol. Chem. , vol.271 , pp. 17920-17926
    • Jiang, Y.1    Chen, C.2    Li, Z.3    Guo, W.4    Gegner, J.A.5    Lin, S.6    Han, J.7
  • 31
    • 0030828701 scopus 로고    scopus 로고
    • Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta
    • Jiang Y., Gram H., Zhao M., New L., Gu J., Feng L., Di Padova F., Ulevitch R.J., and Han J. Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta. J. Biol. Chem. 272 (1997) 30122-30128
    • (1997) J. Biol. Chem. , vol.272 , pp. 30122-30128
    • Jiang, Y.1    Gram, H.2    Zhao, M.3    New, L.4    Gu, J.5    Feng, L.6    Di Padova, F.7    Ulevitch, R.J.8    Han, J.9
  • 32
    • 0035575679 scopus 로고    scopus 로고
    • Programmed cell death: alive and well in the new millennium
    • Kaufmann S.H., and Hengartner M.O. Programmed cell death: alive and well in the new millennium. Trends Cell Biol. 11 (2001) 526-534
    • (2001) Trends Cell Biol. , vol.11 , pp. 526-534
    • Kaufmann, S.H.1    Hengartner, M.O.2
  • 33
    • 0032531823 scopus 로고    scopus 로고
    • Staurosporine-induced apoptosis of cultured rat hippocampal neurons involves caspase-1-like proteases as upstream initiators and increased production of superoxide as a main downstream effector
    • Krohn A.J., Preis E., and Prehn J.H. Staurosporine-induced apoptosis of cultured rat hippocampal neurons involves caspase-1-like proteases as upstream initiators and increased production of superoxide as a main downstream effector. J. Neurosci. 18 (1998) 8186-8197
    • (1998) J. Neurosci. , vol.18 , pp. 8186-8197
    • Krohn, A.J.1    Preis, E.2    Prehn, J.H.3
  • 34
    • 0032006868 scopus 로고    scopus 로고
    • Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells
    • Kruman I., Guo Q., and Mattson M.P. Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells. J. Neurosci. Res. 51 (1998) 293-308
    • (1998) J. Neurosci. Res. , vol.51 , pp. 293-308
    • Kruman, I.1    Guo, Q.2    Mattson, M.P.3
  • 35
    • 0035066383 scopus 로고    scopus 로고
    • Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
    • Kyriakis J.M., and Avruch J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol. Rev. 81 (2001) 807-869
    • (2001) Physiol. Rev. , vol.81 , pp. 807-869
    • Kyriakis, J.M.1    Avruch, J.2
  • 36
    • 0346094368 scopus 로고    scopus 로고
    • Cooperation between PKC-alpha and PKC-epsilon in the regulation of JNK activation in human lung cancer cells
    • Lang W., Wang H., Ding L., and Xiao L. Cooperation between PKC-alpha and PKC-epsilon in the regulation of JNK activation in human lung cancer cells. Cell. Signal. 16 (2004) 457-467
    • (2004) Cell. Signal. , vol.16 , pp. 457-467
    • Lang, W.1    Wang, H.2    Ding, L.3    Xiao, L.4
  • 38
    • 40149094481 scopus 로고    scopus 로고
    • Requirements for PKC-augmented JNK activation by MKK4/7
    • Lopez-Bergami P., and Ronai Z. Requirements for PKC-augmented JNK activation by MKK4/7. Int. J. Biochem. Cell. Biol. 40 (2008) 1055-1064
    • (2008) Int. J. Biochem. Cell. Biol. , vol.40 , pp. 1055-1064
    • Lopez-Bergami, P.1    Ronai, Z.2
  • 40
    • 12844257688 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha- vs. growth factor deprivation-promoted cell death: distinct converging pathways
    • Macdonald N.J., Delderfield S.M., Zhang W., and Taglialatela G. Tumour necrosis factor-alpha- vs. growth factor deprivation-promoted cell death: distinct converging pathways. Aging Cell 2 (2003) 245-256
    • (2003) Aging Cell , vol.2 , pp. 245-256
    • Macdonald, N.J.1    Delderfield, S.M.2    Zhang, W.3    Taglialatela, G.4
  • 41
    • 0032896327 scopus 로고    scopus 로고
    • Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism
    • Martin L.J. Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism. J. Neuropathol. Exp. Neurol. 58 (1999) 459-471
    • (1999) J. Neuropathol. Exp. Neurol. , vol.58 , pp. 459-471
    • Martin, L.J.1
  • 42
    • 0036320954 scopus 로고    scopus 로고
    • Inhibition of oxidative stress produced by plasma membrane NADH oxidase delays low-potassium-induced apoptosis of cerebellar granule cells
    • Martin-Romero F.J., Garcia-Martin E., and Gutierrez-Merino C. Inhibition of oxidative stress produced by plasma membrane NADH oxidase delays low-potassium-induced apoptosis of cerebellar granule cells. J. Neurochem. 82 (2002) 705-715
    • (2002) J. Neurochem. , vol.82 , pp. 705-715
    • Martin-Romero, F.J.1    Garcia-Martin, E.2    Gutierrez-Merino, C.3
  • 43
    • 0029909560 scopus 로고    scopus 로고
    • Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells
    • Miller T.M., and Johnson Jr. E.M. Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells. J. Neurosci. 16 (1996) 7487-7495
    • (1996) J. Neurosci. , vol.16 , pp. 7487-7495
    • Miller, T.M.1    Johnson Jr., E.M.2
  • 44
    • 0032802311 scopus 로고    scopus 로고
    • Caspase-3 expression by cerebellar granule neurons is regulated by calcium and cyclic AMP
    • Moran J., Itoh T., Reddy U.R., Chen M., Alnemri E.S., and Pleasure D. Caspase-3 expression by cerebellar granule neurons is regulated by calcium and cyclic AMP. J. Neurochem. 73 (1999) 568-577
    • (1999) J. Neurochem. , vol.73 , pp. 568-577
    • Moran, J.1    Itoh, T.2    Reddy, U.R.3    Chen, M.4    Alnemri, E.S.5    Pleasure, D.6
  • 45
    • 0024500773 scopus 로고
    • Effect of potassium depolarization on phosphate-activated glutaminase activity in primary cultures of cerebellar granule neurons and astroglial cells during development
    • Moran J., and Patel A.J. Effect of potassium depolarization on phosphate-activated glutaminase activity in primary cultures of cerebellar granule neurons and astroglial cells during development. Brain Res. Dev. Brain Res. 46 (1989) 97-105
    • (1989) Brain Res. Dev. Brain Res. , vol.46 , pp. 97-105
    • Moran, J.1    Patel, A.J.2
  • 46
    • 39149085654 scopus 로고    scopus 로고
    • Caffeine activates the PI3K/Akt pathway and prevents apoptotic cell death in a Parkinson's disease model of SH-SY5Y cells
    • Nakaso K., Ito S., and Nakashima K. Caffeine activates the PI3K/Akt pathway and prevents apoptotic cell death in a Parkinson's disease model of SH-SY5Y cells. Neurosci. Lett. 432 (2008) 146-150
    • (2008) Neurosci. Lett. , vol.432 , pp. 146-150
    • Nakaso, K.1    Ito, S.2    Nakashima, K.3
  • 47
    • 0031021770 scopus 로고    scopus 로고
    • Biochemical and temporal analysis of events associated with apoptosis induced by lowering the extracellular potassium concentration in mouse cerebellar granule neurons
    • Nardi N., Avidan G., Daily D., Zilkha-Falb R., and Barzilai A. Biochemical and temporal analysis of events associated with apoptosis induced by lowering the extracellular potassium concentration in mouse cerebellar granule neurons. J. Neurochem. 68 (1997) 750-759
    • (1997) J. Neurochem. , vol.68 , pp. 750-759
    • Nardi, N.1    Avidan, G.2    Daily, D.3    Zilkha-Falb, R.4    Barzilai, A.5
  • 48
    • 33748145128 scopus 로고    scopus 로고
    • AIF translocates to the nucleus in the spinal motor neurons in a mouse model of ALS
    • Oh Y.K., Shin K.S., and Kang S.J. AIF translocates to the nucleus in the spinal motor neurons in a mouse model of ALS. Neurosci. Lett. 406 (2006) 205-210
    • (2006) Neurosci. Lett. , vol.406 , pp. 205-210
    • Oh, Y.K.1    Shin, K.S.2    Kang, S.J.3
  • 49
    • 0026058318 scopus 로고
    • Cell death during development of the nervous system
    • Oppenheim R.W. Cell death during development of the nervous system. Annu. Rev. Neurosci. 14 (1991) 453-501
    • (1991) Annu. Rev. Neurosci. , vol.14 , pp. 453-501
    • Oppenheim, R.W.1
  • 50
    • 34548205302 scopus 로고    scopus 로고
    • Heteromeric complex formation of ASK2 and ASK1 regulates stress-induced signaling
    • Ortner E., and Moelling K. Heteromeric complex formation of ASK2 and ASK1 regulates stress-induced signaling. Biochem. Biophys. Res. Commun. 362 (2007) 454-459
    • (2007) Biochem. Biophys. Res. Commun. , vol.362 , pp. 454-459
    • Ortner, E.1    Moelling, K.2
  • 51
    • 36849000872 scopus 로고    scopus 로고
    • Canonical and alternative MAPK signaling
    • Pimienta G., and Pascual J. Canonical and alternative MAPK signaling. Cell Cycle 6 (2007) 2628-2632
    • (2007) Cell Cycle , vol.6 , pp. 2628-2632
    • Pimienta, G.1    Pascual, J.2
  • 54
    • 34248597065 scopus 로고    scopus 로고
    • Differential regulation and properties of MAPKs
    • Raman M., Chen W., and Cobb M.H. Differential regulation and properties of MAPKs. Oncogene 26 (2007) 3100-3112
    • (2007) Oncogene , vol.26 , pp. 3100-3112
    • Raman, M.1    Chen, W.2    Cobb, M.H.3
  • 57
    • 2942596005 scopus 로고    scopus 로고
    • Kaempferol blocks oxidative stress in cerebellar granule cells and reveals a key role for reactive oxygen species production at the plasma membrane in the commitment to apoptosis
    • Samhan-Arias A.K., Martin-Romero F.J., and Gutierrez-Merino C. Kaempferol blocks oxidative stress in cerebellar granule cells and reveals a key role for reactive oxygen species production at the plasma membrane in the commitment to apoptosis. Free Radic. Biol. Med. 37 (2004) 48-61
    • (2004) Free Radic. Biol. Med. , vol.37 , pp. 48-61
    • Samhan-Arias, A.K.1    Martin-Romero, F.J.2    Gutierrez-Merino, C.3
  • 58
    • 0035884625 scopus 로고    scopus 로고
    • Flavonoids protect neurons from oxidized low-density-lipoprotein-induced apoptosis involving c-Jun N-terminal kinase (JNK), c-Jun and caspase-3
    • Schroeter H., Spencer J.P., Rice-Evans C., and Williams R.J. Flavonoids protect neurons from oxidized low-density-lipoprotein-induced apoptosis involving c-Jun N-terminal kinase (JNK), c-Jun and caspase-3. Biochem. J. 358 (2001) 547-557
    • (2001) Biochem. J. , vol.358 , pp. 547-557
    • Schroeter, H.1    Spencer, J.P.2    Rice-Evans, C.3    Williams, R.J.4
  • 59
    • 0029954311 scopus 로고    scopus 로고
    • Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species
    • Schulz J.B., Weller M., and Klockgether T. Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species. J. Neurosci. 16 (1996) 4696-4706
    • (1996) J. Neurosci. , vol.16 , pp. 4696-4706
    • Schulz, J.B.1    Weller, M.2    Klockgether, T.3
  • 60
    • 0037378897 scopus 로고    scopus 로고
    • Apoptosis in Parkinson's disease: signals for neuronal degradation
    • (discussion; S70-62)
    • Tatton W.G., Chalmers-Redman R., Brown D., and Tatton N. Apoptosis in Parkinson's disease: signals for neuronal degradation. Ann. Neurol. 53 Suppl. 3 (2003) S61-70 (discussion; S70-62)
    • (2003) Ann. Neurol. , vol.53 , Issue.SUPPL. 3
    • Tatton, W.G.1    Chalmers-Redman, R.2    Brown, D.3    Tatton, N.4
  • 62
    • 0033567291 scopus 로고    scopus 로고
    • The stress-activated protein kinase pathways
    • Tibbles L.A., and Woodgett J.R. The stress-activated protein kinase pathways. Cell. Mol. Life Sci. 55 (1999) 1230-1254
    • (1999) Cell. Mol. Life Sci. , vol.55 , pp. 1230-1254
    • Tibbles, L.A.1    Woodgett, J.R.2
  • 64
    • 0036193169 scopus 로고    scopus 로고
    • Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer
    • Tobiume K., Saitoh M., and Ichijo H. Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer. J. Cell. Physiol. 191 (2002) 95-104
    • (2002) J. Cell. Physiol. , vol.191 , pp. 95-104
    • Tobiume, K.1    Saitoh, M.2    Ichijo, H.3
  • 66
    • 0035341089 scopus 로고    scopus 로고
    • Role of oxidative stress in the apoptotic cell death of cultured cerebellar granule neurons
    • Valencia A., and Moran J. Role of oxidative stress in the apoptotic cell death of cultured cerebellar granule neurons. J. Neurosci. Res. 64 (2001) 284-297
    • (2001) J. Neurosci. Res. , vol.64 , pp. 284-297
    • Valencia, A.1    Moran, J.2
  • 67
    • 1842785859 scopus 로고    scopus 로고
    • Reactive oxygen species induce different cell death mechanisms in cultured neurons
    • Valencia A., and Moran J. Reactive oxygen species induce different cell death mechanisms in cultured neurons. Free Radic. Biol. Med. 36 (2004) 1112-1125
    • (2004) Free Radic. Biol. Med. , vol.36 , pp. 1112-1125
    • Valencia, A.1    Moran, J.2
  • 68
    • 2342562556 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases in apoptosis regulation
    • Wada T., and Penninger J.M. Mitogen-activated protein kinases in apoptosis regulation. Oncogene 23 (2004) 2838-2849
    • (2004) Oncogene , vol.23 , pp. 2838-2849
    • Wada, T.1    Penninger, J.M.2
  • 69
    • 0348140940 scopus 로고    scopus 로고
    • Regulation of c-Jun N-terminal kinase activation in hydrogen peroxide induced neurotoxicity
    • Wang W., Hou X.Y., Gao C., Liu Y., Zong Y.Y., and Zhang G.Y. Regulation of c-Jun N-terminal kinase activation in hydrogen peroxide induced neurotoxicity. J. Neurocytol. 32 (2003) 143-151
    • (2003) J. Neurocytol. , vol.32 , pp. 143-151
    • Wang, W.1    Hou, X.Y.2    Gao, C.3    Liu, Y.4    Zong, Y.Y.5    Zhang, G.Y.6
  • 70
    • 0031972678 scopus 로고    scopus 로고
    • Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons
    • Watson A., Eilers A., Lallemand D., Kyriakis J., Rubin L.L., and Ham J. Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons. J. Neurosci. 18 (1998) 751-762
    • (1998) J. Neurosci. , vol.18 , pp. 751-762
    • Watson, A.1    Eilers, A.2    Lallemand, D.3    Kyriakis, J.4    Rubin, L.L.5    Ham, J.6
  • 71
    • 0032928614 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human
    • Widmann C., Gibson S., Jarpe M.B., and Johnson G.L. Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human. Physiol. Rev. 79 (1999) 143-180
    • (1999) Physiol. Rev. , vol.79 , pp. 143-180
    • Widmann, C.1    Gibson, S.2    Jarpe, M.B.3    Johnson, G.L.4
  • 72
    • 24744463641 scopus 로고    scopus 로고
    • Apoptotic signals within the basal forebrain cholinergic neurons in Alzheimer's disease
    • Wu C.K., Thal L., Pizzo D., Hansen L., Masliah E., and Geula C. Apoptotic signals within the basal forebrain cholinergic neurons in Alzheimer's disease. Exp. Neurol. 195 (2005) 484-496
    • (2005) Exp. Neurol. , vol.195 , pp. 484-496
    • Wu, C.K.1    Thal, L.2    Pizzo, D.3    Hansen, L.4    Masliah, E.5    Geula, C.6
  • 74
    • 0242391823 scopus 로고    scopus 로고
    • Comparison of inhibitory effects of brain-derived neurotrophic factor and insulin-like growth factor on low potassium-induced apoptosis and activation of p38 MAPK and c-Jun in cultured cerebellar granule neurons
    • Yamagishi S., Matsumoto T., Yokomaku D., Hatanaka H., Shimoke K., Yamada M., and Ikeuchi T. Comparison of inhibitory effects of brain-derived neurotrophic factor and insulin-like growth factor on low potassium-induced apoptosis and activation of p38 MAPK and c-Jun in cultured cerebellar granule neurons. Brain Res. Mol. Brain Res. 119 (2003) 184-191
    • (2003) Brain Res. Mol. Brain Res. , vol.119 , pp. 184-191
    • Yamagishi, S.1    Matsumoto, T.2    Yokomaku, D.3    Hatanaka, H.4    Shimoke, K.5    Yamada, M.6    Ikeuchi, T.7
  • 75
    • 0033587773 scopus 로고    scopus 로고
    • Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins
    • Zhang L., Chen J., and Fu H. Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 8511-8515
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 8511-8515
    • Zhang, L.1    Chen, J.2    Fu, H.3
  • 76
    • 36448982508 scopus 로고    scopus 로고
    • Superoxide dismutase/catalase mimetics but not MAP kinase inhibitors are neuroprotective against oxygen/glucose deprivation-induced neuronal death in hippocampus
    • Zhou M., Dominguez R., and Baudry M. Superoxide dismutase/catalase mimetics but not MAP kinase inhibitors are neuroprotective against oxygen/glucose deprivation-induced neuronal death in hippocampus. J. Neurochem. 103 (2007) 2212-2223
    • (2007) J. Neurochem. , vol.103 , pp. 2212-2223
    • Zhou, M.1    Dominguez, R.2    Baudry, M.3
  • 77
    • 37349081929 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase regulates mitochondrial bioenergetics by modulating pyruvate dehydrogenase activity in primary cortical neurons
    • Zhou Q., Lam P.Y., Han D., and Cadenas E. c-Jun N-terminal kinase regulates mitochondrial bioenergetics by modulating pyruvate dehydrogenase activity in primary cortical neurons. J. Neurochem. 104 (2008) 325-335
    • (2008) J. Neurochem. , vol.104 , pp. 325-335
    • Zhou, Q.1    Lam, P.Y.2    Han, D.3    Cadenas, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.