Chronic intermittent hypoxia down-regulates endothelial nitric oxide synthase expression by an NF-κB-dependent mechanism

Sleep Medicine

Volumn 14, Issue 2, 2013, Pages 165-171

  Wang, Baoshan ^a   Yan, Baoyong ^a   Song, Dongmei ^a   Ye, Xiaobing ^b   Liu, Shu Fang ^b  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

Acetylcholine; Endothelial nitric oxide synthase; Endothelium; Intermittent hypoxia; NF B; Obstructive sleep apnea

Indexed keywords

ACETYLCHOLINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITROPRUSSIDE SODIUM; PROTEIN P50; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; CHRONIC INTERMITTENT HYPOXIA; CONTROLLED STUDY; DISEASE ACTIVITY; DOWN REGULATION; ENDOTHELIUM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME REGULATION; GENE DELETION; IN VITRO STUDY; IN VIVO STUDY; MESENTERIC ARTERY; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; SLEEP DISORDERED BREATHING; TISSUE LEVEL; UPREGULATION; VASOCONSTRICTION; VASODILATATION;

ACETYLCHOLINE; ANIMALS; ANOXIA; BLOOD PRESSURE; DOWN-REGULATION; HUMANS; MICE; MICE, KNOCKOUT; NF-KAPPA B P50 SUBUNIT; NITRIC OXIDE SYNTHASE TYPE III; NITROPRUSSIDE; SLEEP APNEA, OBSTRUCTIVE; TUMOR NECROSIS FACTOR-ALPHA; VASODILATION; VASODILATOR AGENTS;

EID: 84873525913     PISSN: 13899457     EISSN: 18785506     Source Type: Journal    
DOI: 10.1016/j.sleep.2012.10.020     Document Type: Article

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