Verbal and visual-spatial memory impairment in youth at familial risk for schizophrenia or affective psychosis: A pilot study

Schizophrenia Research

Volumn 144, Issue 1-3, 2013, Pages 122-128

  Scala, Silvia ^a,b   Pousada, Andrea ^b   Stone, William S ^b   Thermenos, Heidi W ^b,c   Manschreck, Theo C ^d   Tsuang, Ming T ^b,e   Faraone, Stephen V ^f   Seidman, Larry J ^b,c  

^a UNIVERSITY OF VERONA   (Italy)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d MASSACHUSETTS DEPARTMENT OF PUBLIC HEALTH   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f State University of New York Upstate Medical University: College of Medicine   (United States)

Author keywords

Family high risk; Memory; Psychopathology; Psychosis; Vulnerability

Indexed keywords

PSYCHOTROPIC AGENT;

ADOLESCENT; ADULT; ALERTNESS; ANALYSIS OF COVARIANCE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EFFECT SIZE; FAMILIAL DISEASE; FEMALE; HUMAN; IMAGE PROCESSING; MALE; MEMORY CONSOLIDATION; MENTAL PERFORMANCE; NEUROIMAGING; NEUROPSYCHOLOGY; PRIORITY JOURNAL; PSYCHOTHERAPY; RISK ASSESSMENT; RISK FACTOR; SCHIZOPHRENIA; SPATIAL MEMORY; VERBAL MEMORY; VISUAL MEMORY;

ADOLESCENT; ADULT; AFFECTIVE DISORDERS, PSYCHOTIC; ATTENTION; EXECUTIVE FUNCTION; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MEMORY DISORDERS; MEMORY, SHORT-TERM; MENTAL RECALL; NEUROPSYCHOLOGICAL TESTS; PILOT PROJECTS; PSYCHIATRIC STATUS RATING SCALES; SCHIZOPHRENIA; WECHSLER SCALES; YOUNG ADULT;

EID: 84873522019     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2012.11.027     Document Type: Article

References (71)

1. Agnew-Blais J., Seidman L.J. Neurocognition in youth and young adults under age 30 at familial risk for schizophrenia: a quantitative and qualitative review. Cogn. Neuropsychiatry 2012, 10.1080/13546805.2012.676309.
2. Aleman A., Hijman R., de Haan E.H., Kahn R.S. Memory impairment in schizophrenia: a meta-analysis. Am. J. Psychiatry 1999, 156:1358-1366.
3. A.P.Association Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) 1994, American Psychiatric Association, Washington, DC.
4. Arts B., Jabben N., Krabbendam L., van Os J. Meta-analyses of cognitive functioning in euthymic bipolar patients and their first-degree relatives. Psychol. Med. 2008, 38:771-785.
5. Balanzá-Martínez V., Rubio C., Selva-Vera G., Martinez-Aran A., Sánchez-Moreno J., Salazar-Fraile J., Vieta E., Tabarés-Seisdedos R. Neurocognitive endophenotypes (endophenocognitypes) from studies of relatives of bipolar disorder subjects: a systematic review. Neurosci. Biobehav. Rev. 2008, 32:1426-1438.
6. Bearden C.E., Glahn D.C., Monkul E.S., Barrett J., Najt P.N., Villarreal V., Soares J.C. Patterns of memory impairment in bipolar disorder and unipolar major depression. Psychiatry Res. 2006, 142:139-150.
7. Bernstein J.H., Weber D.P. Developmental Scoring System of the Rey Osterrieth Complex Figure 1996, Psychological Assessment Resources, Odessa, FL.
8. Christensen M.V., Kyvik K.O., Kessing L.V. Cognitive function in unaffected twins discordant for affective disorder. Psychol. Med. 2006, 36:1119-1129.
9. Cirillo M.A., Seidman L.J. Verbal declarative memory dysfunction in schizophrenia: from clinical assessment to genetics and brain mechanisms. Neuropsychol. Rev. 2003, 13:43-77.
10. Cohen J. Statistical Power Analysis for the Behavioral Sciences 1988, Lawrence Earlbaum Associates, Hillsdale, NJ. 2nd ed.
11. Conklin H.M., Calkins M.E., Anderson C.W., Dinzeo T.J., Iacono W.G. Recognition memory for faces in schizophrenia patients and their first-degree relatives. Neuropsychologia 2002, 40:2314-2324.
12. Conklin H.M., Curtis C.E., Katsanis J., Iacono W.G. Verbal working memory impairment in schizophrenia patients and their first-degree relatives: evidence from the digit span task. Am. J. Psychiatry 2000, 157:275-277.
13. Craddock N., O'Donovan M., Owen M. Genes for schizophrenia and bipolar disorder: dissecting psychosis. J. Med. Genet. 2005, 42:193-204.
14. de la Serna E., Baeza I., Toro J., Andrés S., Puig O., Sánchez-Guistau V., Romero S., Bernardo M., Castro-Fornieles J. Relationship between clinical and neuropsychological characteristics in child and adolescent first-degree relatives of subjects with schizophrenia. Schizophr. Res. 2010, 116:159-167.
15. Derogatis L.R. Symptom Checklist-90-R (SCL-90) 1993, Computer Systems, Minneapolis.
16. Dittmann S., Hennig-Fast K., Gerber S., Seemüller F., Riedel M., Emanuel Severus W., Langosch J., Engel R.R., Möller H.J., Grunze H.C. Cognitive functioning in euthymic bipolar I and bipolar II patients. Bipolar Disord. 2008, 10:877-887.
17. Erlenmeyer-Kimling L., Rock D., Roberts S.A., Janal M., Kestenbaum C., Cornblatt B., Adamo U.H., Gottesman I.I. Attention, memory, and motor skills as childhood predictors of schizophrenia-related psychoses: the New York High-Risk Project. Am. J. Psychiatry 2000, 157:1416-1422.
18. Faraone S.V., Seidman L.J., Kremen W.S., Pepple J.R., Lyons M.J., Tsuang M.T. Neuropsychological functioning among the nonpsychotic relatives of schizophrenic patients: a diagnostic efficiency analysis. J. Abnorm. Psychol. 1995, 104:286-304.
19. Ferrier I.N., Stanton B.R., Kelly T.P., Scott J. Neuropsychological function in euthymic patients with bipolar disorder. Br. J. Psychiatry 1999, 175:246-251.
20. Ferrier I.N., Chowdray R., Thompson J.M., Watson S., Young A.H. Neurocognitive function in unaffected first-degree relatives of patients with bipolar disorder: a preliminary report. Bipolar Disord. 2004, 6:319-322.
21. Fossati P., Harvey P.O., Le Bastard G., Ergis A.M., Jouvent R., Allilaire J.F. Verbal memory performance of patients with a first depressive episode and patients with unipolar and bipolar recurrent depression. J. Psychiatr. Res. 2004, 38:137-144.
22. Geller B., Zimerman B., Williams M., Frazier J. WASH-U-KSADS (Washington University at St. Louis Kiddie and Young Adult Schedule for Affective Disorders and Schizophrenia - Lifetime and Present Episode Version-DSM-IV) 1994, Washington University School of Medicine, St. Louis, MO, (revised 1996).
23. Glahn D.C., Barrett J., Bearden C.E., Mintz J., Green M.F., Serap Monkul E., Najt P., Soares J.C., Velligan D.I. Dissociable mechanisms for memory impairment in bipolar disorder and schizophrenia. Psychol. Med. 2006, 36:1085-1095.
24. Glahn D.C., Almasy L., Barguil M., Hare E., Peralta J.M., Kent J.W., Dassori A., Contreras J., Pacheco A., Lanzagorta N., Nicolini H., Raventós H., Escamilla M.A. Neurocognitive endophenotypes for bipolar disorders identified in multiplex multigenerational families. Arch. Gen. Psychiatry 2010, 67:168-177.
25. Goldberg T.E., Gold J.M., Greenberg R., Griffin S., Schulz S.C., Pickar D., Kleinman J.E., Weinberger D.R. Contrasts between patients with affective disorders and patients with schizophrenia on a neuropsychological test battery. Am. J. Psychiatry 1993, 150:1355-1362.
26. Goodwin F.K., Jamison K.R. Manic-Depressive Illness 1990, Oxford University Press, New York.
27. Gottesman I.I., Gould T.D. The endophenotype concept in psychiatry: etymology and strategic intentions. Am. J. Psychiatry 2003, 160:636-645.
28. Heinrichs R.W., Zakzanis K.K. Neurocognitive deficit in schizophrenia: a quantitative review of the evidence. Neuropsychology 1998, 12:426-445.
29. Hollingshead A.B. Four Factor Index of Social Status 1975, Yale University Department of Sociology, New Heaven.
30. Jabben N., Arts B., van Os J., Krabbendam L. Neurocognitive functioning as intermediary phenotype and predictor of psychosocial functioning across the psychosis continuum: studies in schizophrenia and bipolar disorder. J. Clin. Psychiatry 2010, 71:764-774.
31. Jones B.P., Mirsky A.F., Duncan C.C. ROCF performance, attention disorders, and neuropsychiatric disorders. The Handbook of the Rey-Osterrieth Complex Figure Usage: Clinical and Research Applications 2003, 19:441-451. PAR, Inc. J.A. Knight (Ed.).
32. Kalinowski A.G., Weinstein C.S., Seidman L.J. Organizational and retrieval deficits on the Rey-Osterrieth Complex Figure in schizophrenia. The Rey-Osterrieth Handbook 2003, 463-475. Psychological Assessment Resources, Odessa, FL. J. Knight, E.F. Kaplan (Eds.).
33. Kieseppä T., Tuulio-Henriksson A., Haukka J., Van Erp T., Glahn D., Cannon T.D., Partonen T., Kaprio J., Lönnqvist J. Memory and verbal learning functions in twins with bipolar I disorder, and the role of information-processing speed. Psychol. Med. 2005, 35:205-215.
34. Kraepelin, E., 1974 Die Erscheinungsformen des Irreseins. Zeitschrift Gesamte Neurologie Psychiatrie 1920; 62: 1-29. (translated by H Marshall as: Patterns of mental disorder. In: Themes and Variations in European Psychiatry. Eds S.R. Hirsch & M. Shepherd. Wright, Bristol. 7-30.
35. Kremen W.S., Seidman L.J., Pepple J.R., Lyons M.J., Tsuang M.T., Faraone S.V. Neuropsychological risk indicators for schizophrenia: a review of family studies. Schizophr. Bull.1994 , 20:103-119.
36. Kremen W.S., Faraone S.V., Seidman L.J., Pepple J.R., Tsuang M.T. Neuropsychological risk indicators for schizophrenia: a preliminary study of female relatives of schizophrenic and bipolar probands. Psychiatry Res. 1998, 79:227-240.
37. Lewandowski K.E., Cohen B.M., Ongur D. Evolution of neuropsychological dysfunction during the course of schizophrenia and bipolar disorder. Psychol. Med. 2011, 41:225-241.
38. Manschreck T.C., Maher B.A., Beaudette S., Redmond D. Context memory in schizoaffective and schizophrenic disorders. Schizophr. Res. 1997, 26:153-161.
39. Maxwell E.M. Manual for the FIGS Retrieved from. http://zork.wustl.edu/nimh/digs/newpage11.htm.
40. Maziade M., Rouleau N., Gingras N., Boutin P., Paradis M., Jomphe V., Boutin J., Létourneau K., Gilbert E., Lefebvre E., Dore M., Marino C., Battaglia M., Mérette C., Roy M. Shared neurocognitive dysfunctions in young offspring at extreme risk for schizophrenia or bipolar disorder in eastern Quebec multigenerational families. Schizophr. Bull. 2009, 35:919-930.
41. McIntosh A.M., Harrison L.K., Forrester K., Lawrie S.M., Johnstone E.C. Neuropsychological impairments in people with schizophrenia or bipolar disorder and their unaffected relatives. Br. J. Psychiatry 2005, 186:378-385.
42. Mesholam-Gately R., Giuliano A.J., Faraone S.V., Goff K.P., Seidman L.J. Neurocognition in first-episode schizophrenia: a meta-analytic review. Neuropsychology 2009, 23:315-336.
43. Miller G.A., Selfridge J. Verbal context and the recall of meaningful material. Am. J. Psychol. 1950, 63:176-185.
44. Nurnberger J.I.Jr, Blehar M.C., Kaufmann C.A., York-Cooler C., Simpson S.G., Harkavy-Friedman J., Severe J.B., Malaspina D., Reich T. Diagnostic interview for genetic studies. Rationale, unique features, and training. NIMH Genetics Initiative. Arch. Gen. Psychiatry 1994, 51:849-859. (discussion 863-4).
45. Osterrieth P.A. Filetest de copie d'une figure complex: Contribution a l'etude de la perception et de la memoire [The test of copying a complex figure: a contribution to the study of perception and memory]. Arch. Psychol. 1944, 30:286-356.
46. Pirkola T., Tuulio-Henriksson A., Glahn D., Kieseppä T., Haukka J., Kaprio J., Lönnqvist J., Cannon T.D. Spatial working memory function in twins with schizophrenia and bipolar disorder. Biol. Psychiatry 2005, 58:930-936.
47. Rey A. L'examen psychologique dans les cas d'encephalopathie traumatique. (Les problems.). Arch. Psychol. 1941, 28:215-285.
48. Robinson L.J., Thompson J.M., Gallagher P., Goswami U., Young A.H., Ferrier I.N., Moore P.B. A meta-analysis of cognitive deficits in euthymic patients with bipolar disorder. J. Affect. Disord. 2006, 93:105-115.
49. Rubinsztein J.S., Micahel A., Paykel E.S., Sahakian B.J. Cognitive impairment in remission in bipolar affective disorder. Psychol. Med. 2000, 30:1025-1036.
50. Schretlen D.J., Cascella N.G., Meyer S.M., Kingery L.R., Testa S.M., Munro C.A., Pulver A.E., Rivkin P., Rao V.A., Diaz-Asper C.M., Dickerson F.B., Yolken R.H., Pearlson G.D. Neuropsychological functioning in bipolar disorder and schizophrenia. Biol. Psychiatry 2007, 62:179-186.
51. Schubert E.W., McNeil T.F. Neuropsychological impairment and its neurological correlates in adult offspring with heightened risk for schizophrenia and affective psychosis. Am. J. Psychiatry 2005, 162:758-766.
52. Seidman L.J., Breiter H., Goodman J.M., Goldstein J.M., Woodruff P., O'Craven K., Savoy R., Tsuang M.T., Rosen B.R. A functional magnetic resonance imaging study of auditory vigilance with low and high information processing demands. Neuropsychology 1998, 12:505-518.
53. Seidman L.J., Cherkerzian S., Goldstein J.M., Agnew-Blais J., Tsuang M.T., Buka S.L. Neuropsychological performance and family history in children at age 7 who develop adult schizophrenia or bipolar psychosis in the New England High-Risk Family Study. Psychol. Med. 2013, 43:119-131.
54. Seidman L.J., Kremen W.S., Koren D., Faraone S.V., Goldstein J.M., Tsuang M.T. A comparative profile analysis of neuropsychological functioning in patients with schizophrenia and bipolar psychoses. Schizophr. Res. 2002, 53:31-44.
55. Seidman L.J., Lanca M., Kremen W.S., Faraone S.V., Tsuang M.T. Organizational and visual memory deficits in schizophrenia and bipolar psychoses using the Rey-Osterrieth Complex Figure: effects of duration of illness. J. Clin. Exp. Neuropsychol. 2003, 25:949-964.
56. Seidman L.J., Giuliano A.J., Smith C.W., Stone W.S., Glatt S.J., Meyer E., Faraone S.V., Tsuang M.T., Cornblatt B. Neuropsychological functioning in adolescents and young adults at genetic risk for schizophrenia and affective psychoses: results from the Harvard and Hillside Adolescent High Risk Studies. Schizophr. Bull. 2006, 32:507-524.
57. Seidman L.J., Meyer E., Giuliano A.J., Breiter H., Goldstein J.M., Kremen W.S., Thermenos H., Toomey R., Stone W.S., Tsuang M.T., Faraone S.V. Auditory working memory impairments in individuals at familial high risk for schizophrenia. Neuropsychology 2012, 26:288-303.
58. Skelley S.L., Goldberg T.E., Egan M.F., Weinberger D.R., Gold J.M. Verbal and visual memory: characterizing the clinical and intermediate phenotype in schizophrenia. Schizophr. Res. 2008, 105:78-85.
59. Snitz B.E., Macdonald A.W., Carter C.S. Cognitive deficits in unaffected first-degree relatives of schizophrenia patients: a meta-analytic review of putative endophenotypes. Schizophr. Bull. 2006, 32:179-194.
60. Sullivan E.V., Mathalon D.H., Ha C.N., Zipursky R.B., Pfefferman A. The contribution of constructional accuracy and organizational strategy to nonverbal recall in schizophrenia and chronic alcoholism. Biol. Psychiatry 1992, 32:312-333.
61. Sweeney J.A., Kmiec J.A., Kupfer D.J. Neuropsychologic impairments in bipolar and unipolar mood disorders on the CANTAB neurocognitive battery. Biol. Psychiatry 2000, 48:674-685.
62. Thermenos H.W., Seidman L.J., Poldrack R.A., Peace N.K., Koch J.K., Faraone S.V., Tsuang M.T. Elaborative verbal encoding and altered anterior parahippocampal activation in adolescents and young adults at genetic risk for schizophrenia using FMRI. Biol. Psychiatry 2007, 61:564-574.
63. Tracy J.I., Mattson R., King C., Bundick T., Celenza M.A., Glosser G. A comparison of memory for verbal and non-verbal material in schizophrenia. Schizophr. Res. 2001, 50:199-211.
64. Trandafir A., Méary A., Schurhoff F., Leboyer M., Szoke A. Memory tests in first degree adult relatives of schizophrenic patients: a meta-analysis. Schizophr. Res. 2006, 81:217-226.
65. Tremont G., Halpert S., Javorsky D.J., Stern R.A. Differential impact of executive dysfunction on verbal list learning and story recall. Clin. Neuropsychol. 2000, 14:295-302.
66. Tuulio-Henriksson A., Arajarvi R., Partonen T., Haukka J., Varilo T., Schreck M., Cannon T., Lonnqvist J. Familial loading associates with impairment in visual span among healthy siblings of schizophrenia patients. Biol. Psychiatry 2003, 54:623-628.
67. Wechsler D. WISC-III: Wechsler Intelligence Scale for Children 1991, The Psychological Corporation, New York.
68. Wechsler D. Wechsler Adult Intelligence Scale - Third Edition 1997, The Psychological Corporation, San Antonio.
69. Wilkinson G.S. The Wide Range Achievement Test: Manual 1993, Wide Range, Wilmington, DE. 3rd ed.
70. Zilles D., Burke S., Schneider-Axmann T., Falkai P., Gruber O. Diagnosis-specific effect of familial loading on verbal working memory in schizophrenia. Eur. Arch. Psychiatry Clin. Neurosci. 2009, 259:309-315.
71. Zilles, D., Jung, R., Gruber, E., Falkai, P., Gruber, O., in press. Differential working memory performance as support for the Kraepelinian dichotomy between schizophrenia and bipolar disorder? An experimental neuropsychological study using circuit-specific working memory tasks. The World Journal of Biological Psychiatry. doi:10.3109/15622975.2011.591825.