Treatment with a clinically-relevant dose of methylphenidate alters NMDA receptor composition and synaptic plasticity in the juvenile rat prefrontal cortex

Neurobiology of Learning and Memory

Volumn 101, Issue , 2013, Pages 65-74

  Urban, Kimberly R ^a   Li, Yan Chun ^a   Gao, Wen Jun ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

ADHD; Excitatory synaptic transmission; Juvenile; Methylphenidate; Prefrontal cortex; Psychostimulant; Synaptic plasticity

Indexed keywords

AMPA RECEPTOR; METHYLPHENIDATE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B;

ACUTE DRUG ADMINISTRATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN DEPTH STIMULATION; BRAIN ELECTROPHYSIOLOGY; CONTROLLED STUDY; DOSE RESPONSE; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MALE; MEMORY DISORDER; MOLECULAR WEIGHT; NERVE CELL PLASTICITY; NEUROTRANSMITTER RELEASE; NONHUMAN; PREFRONTAL CORTEX; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; RAT; RECEPTOR POTENTIAL; SYNAPTIC TRANSMISSION; WESTERN BLOTTING; WORKING MEMORY;

ANIMALS; CENTRAL NERVOUS SYSTEM STIMULANTS; EXCITATORY POSTSYNAPTIC POTENTIALS; FEMALE; LONG-TERM POTENTIATION; LONG-TERM SYNAPTIC DEPRESSION; MALE; METHYLPHENIDATE; NEURONAL PLASTICITY; PATCH-CLAMP TECHNIQUES; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPTIC TRANSMISSION;

EID: 84873506685     PISSN: 10747427     EISSN: 10959564     Source Type: Journal    
DOI: 10.1016/j.nlm.2013.01.004     Document Type: Article

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