Lipopolysaccharides with Acylation Defects Potentiate TLR4 Signaling and Shape T Cell Responses

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Martirosyan, Anna ^a,b   Ohne, Yoichiro ^c   Degos, Clara ^a,b   Gorvel, Laurent ^a,b   Moriyón, Ignacio ^d   Oh, Sangkon ^c   Gorvel, Jean Pierre ^a,b  

^a CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^b INSERM   (France)

^c BAYLOR INSTITUTE FOR IMMUNOLOGY RESEARCH   (United States)

^d UNIVERSITY OF NAVARRA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CD40 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GAMMA INTERFERON; HEXA ACYL LIPOPOLYSACCHARIDE; HLA DR ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INITIATION FACTOR 4E BINDING PROTEIN 1; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 6; L SELECTIN; LIPID A; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEASOME; PROTEIN KINASE B; PROTEIN S6; STRESS ACTIVATED PROTEIN KINASE; TETRA ACYL LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACYLATION; ACYLATION DEFECT; ADAPTIVE IMMUNITY; ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; BONE MARROW DERIVED DENDRITIC CELL; BONE MARROW DERIVED MACROPHAGE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CELL MATURATION; CELL SURFACE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; DOWN REGULATION; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; IN VITRO STUDY; INTRACELLULAR SIGNALING; MACROPHAGE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY T LYMPHOCYTE; STRUCTURE ACTIVITY RELATION; UPREGULATION;

ACYLATION; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; GENE EXPRESSION REGULATION; HUMANS; IMMUNITY, INNATE; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; MICE; MICE, TRANSGENIC; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TOLL-LIKE RECEPTOR 4;

EID: 84873491909     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055117     Document Type: Article

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