메뉴 건너뛰기




Volumn 5, Issue 1, 2013, Pages 13-24

Kakkalide ameliorates endothelial insulin resistance by suppressing reactive oxygen species-associated inflammation

Author keywords

Endothelial dysfunction; Inflammation; Insulin resistance; Kakkalide; Reactive oxygen species

Indexed keywords

CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; I KAPPA B KINASE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INTERLEUKIN 6; ISOFLAVONE; KAKKALIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SERINE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; TYROSINE; UNCLASSIFIED DRUG;

EID: 84873477572     PISSN: 17530393     EISSN: 17530407     Source Type: Journal    
DOI: 10.1111/1753-0407.12017     Document Type: Article
Times cited : (23)

References (30)
  • 1
    • 0024352080 scopus 로고
    • Pharmacological studies on Puerariae Flos I. The effects of puerariae flos on alcoholic metabolism and spontaneous movement in mice
    • in Japanese with English abstract).
    • Niiho Y, Yamazaki T, Nakajima Y et al. Pharmacological studies on Puerariae Flos I. The effects of puerariae flos on alcoholic metabolism and spontaneous movement in mice. Yakugaku Zasshi. 1989; 109: 424-31 (in Japanese with English abstract).
    • (1989) Yakugaku Zasshi , vol.109 , pp. 424-431
    • Niiho, Y.1    Yamazaki, T.2    Nakajima, Y.3
  • 3
    • 0030885170 scopus 로고    scopus 로고
    • Pharmacological studies on Puerariae flos III: Protective effects of kakkalide on ethanol-induced lethality and acute hepatic injury in mice
    • Yamazaki T, Nakajima Y, Niho Y et al. Pharmacological studies on Puerariae flos III: Protective effects of kakkalide on ethanol-induced lethality and acute hepatic injury in mice. J Pharm Pharmacol. 1997; 49: 831-3.
    • (1997) J Pharm Pharmacol , vol.49 , pp. 831-833
    • Yamazaki, T.1    Nakajima, Y.2    Niho, Y.3
  • 4
    • 0346245127 scopus 로고    scopus 로고
    • Protective effects of kakkalide from Flos Puerariae on ethanol-induced lethality and hepatic injury are dependent on its biotransformation by human intestinal microflora
    • Han YO, Han MJ, Park SH, Kim DH. Protective effects of kakkalide from Flos Puerariae on ethanol-induced lethality and hepatic injury are dependent on its biotransformation by human intestinal microflora. J Pharmacol Sci. 2003; 93: 331-6.
    • (2003) J Pharmacol Sci , vol.93 , pp. 331-336
    • Han, Y.O.1    Han, M.J.2    Park, S.H.3    Kim, D.H.4
  • 5
    • 21144458955 scopus 로고    scopus 로고
    • Hepatoprotective effects of irisolidone on tert-butyl hyperoxide-induced liver injury
    • Lee HU, Bae EA, Kim DH. Hepatoprotective effects of irisolidone on tert-butyl hyperoxide-induced liver injury. Biol Pharm Bull. 2005; 28: 531-3.
    • (2005) Biol Pharm Bull , vol.28 , pp. 531-533
    • Lee, H.U.1    Bae, E.A.2    Kim, D.H.3
  • 6
    • 35348969777 scopus 로고    scopus 로고
    • Kakkalide and irisolidone: HMG-CoA reductase inhibitors isolated from the flower of Pueraria thunbergiana
    • Min SW, Kim DH. Kakkalide and irisolidone: HMG-CoA reductase inhibitors isolated from the flower of Pueraria thunbergiana. Biol Pharm Bull. 2007; 30: 1965-8.
    • (2007) Biol Pharm Bull , vol.30 , pp. 1965-1968
    • Min, S.W.1    Kim, D.H.2
  • 7
    • 33744944776 scopus 로고    scopus 로고
    • Estrogenic effect of main components kakkalide and tectoridin of Puerariae Flos and their metabolites
    • Shin JE, Bae EA, Lee YC, Ma JY, Kim DH. Estrogenic effect of main components kakkalide and tectoridin of Puerariae Flos and their metabolites. Biol Pharm Bull. 2006; 29: 1202-6.
    • (2006) Biol Pharm Bull , vol.29 , pp. 1202-1206
    • Shin, J.E.1    Bae, E.A.2    Lee, Y.C.3    Ma, J.Y.4    Kim, D.H.5
  • 8
    • 33847091290 scopus 로고    scopus 로고
    • Anti-inflammatory mechanisms of isoflavone metabolites in lipopolysaccharide-stimulated microglial cells
    • Park JS, Woo MS, Kim DH et al. Anti-inflammatory mechanisms of isoflavone metabolites in lipopolysaccharide-stimulated microglial cells. J Pharmacol Exp Ther. 2007; 320: 1237-45.
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 1237-1245
    • Park, J.S.1    Woo, M.S.2    Kim, D.H.3
  • 9
    • 38849204284 scopus 로고    scopus 로고
    • Protective effect of irisolidone, a metabolite of kakkalide, against hydrogen peroxide induced cell damage via antioxidant effect
    • Kang KA, Zhang R, Piao MJ et al. Protective effect of irisolidone, a metabolite of kakkalide, against hydrogen peroxide induced cell damage via antioxidant effect. Bioorg Med Chem. 2008; 16: 1133-41.
    • (2008) Bioorg Med Chem , vol.16 , pp. 1133-1141
    • Kang, K.A.1    Zhang, R.2    Piao, M.J.3
  • 10
    • 0031726145 scopus 로고    scopus 로고
    • Resistance to insulin-mediated glucose disposal as a predictor of cardiovascular disease
    • Yip J, Facchini FS, Reaven GM. Resistance to insulin-mediated glucose disposal as a predictor of cardiovascular disease. J Clin Endocrinol Metab. 1998; 83: 2273-6.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 2273-2276
    • Yip, J.1    Facchini, F.S.2    Reaven, G.M.3
  • 11
    • 78349297565 scopus 로고    scopus 로고
    • Oxidative stress and diabetic complications
    • Giacco F, Brownlee M. Oxidative stress and diabetic complications. Circ Res. 2010; 107: 1058-70.
    • (2010) Circ Res , vol.107 , pp. 1058-1070
    • Giacco, F.1    Brownlee, M.2
  • 12
    • 0038025843 scopus 로고    scopus 로고
    • Stress and vascular responses: Oxidative stress and endothelial dysfunction in the insulin-resistant state
    • Shinozaki K, Kashiwagi A, Masada M, Okamura TJ. Stress and vascular responses: Oxidative stress and endothelial dysfunction in the insulin-resistant state. Pharmacol Sci. 2003; 91: 187-91.
    • (2003) Pharmacol Sci , vol.91 , pp. 187-191
    • Shinozaki, K.1    Kashiwagi, A.2    Masada, M.3    Okamura, T.J.4
  • 14
    • 34547652593 scopus 로고    scopus 로고
    • Impact of mitochondrial ROS production on diabetic vascular complications
    • Nishikawa T, Kukidome D, Sonoda K et al. Impact of mitochondrial ROS production on diabetic vascular complications. Diabetes Res Clin Pract. 2007; 77 (Suppl. 1): S41-5.
    • (2007) Diabetes Res Clin Pract , vol.77 , Issue.SUPPL. 1
    • Nishikawa, T.1    Kukidome, D.2    Sonoda, K.3
  • 15
    • 33745948085 scopus 로고    scopus 로고
    • Insulin resistance and endothelial dysfunction: The road map to cardiovascular diseases
    • Cersosimo E, DeFronzo RA. Insulin resistance and endothelial dysfunction: The road map to cardiovascular diseases. Diabetes Metab Res Rev. 2006; 22: 423-36.
    • (2006) Diabetes Metab Res Rev , vol.22 , pp. 423-436
    • Cersosimo, E.1    DeFronzo, R.A.2
  • 16
    • 0030921893 scopus 로고    scopus 로고
    • Elevated circulating free fatty acid levels impair endothelium-dependent vasodilation
    • Steinberg HO, Tarshoby M, Monestel R et al. Elevated circulating free fatty acid levels impair endothelium-dependent vasodilation. J Clin Invest. 1997; 100: 1230-9.
    • (1997) J Clin Invest , vol.100 , pp. 1230-1239
    • Steinberg, H.O.1    Tarshoby, M.2    Monestel, R.3
  • 17
    • 0033944950 scopus 로고    scopus 로고
    • Free fatty acid elevation impairs insulin-mediated vasodilation and nitric oxide production
    • Steinberg HO, Paradisi G, Hook G, Crowder K, Cronin J, Baron AD. Free fatty acid elevation impairs insulin-mediated vasodilation and nitric oxide production. Diabetes. 2000; 49: 1231-8.
    • (2000) Diabetes , vol.49 , pp. 1231-1238
    • Steinberg, H.O.1    Paradisi, G.2    Hook, G.3    Crowder, K.4    Cronin, J.5    Baron, A.D.6
  • 18
    • 0034123173 scopus 로고    scopus 로고
    • High levels of nonesterified fatty acids are associated with increased familial risk of cardiovascular disease
    • Carlsson M, Wessman Y, Almgren P, Groop L. High levels of nonesterified fatty acids are associated with increased familial risk of cardiovascular disease. Arterioscler Thromb Vasc Biol. 2000; 20: 1588-94.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1588-1594
    • Carlsson, M.1    Wessman, Y.2    Almgren, P.3    Groop, L.4
  • 19
    • 48749100078 scopus 로고    scopus 로고
    • Palmitate increases superoxide production through mitochondrial electron transport chain and NADPH oxidase activity in skeletal muscle cells
    • Lambertucci RH, Hirabara SM, Silveira Ldos R, Levada-Pires AC, Curi R, Pithon-Curi TC. Palmitate increases superoxide production through mitochondrial electron transport chain and NADPH oxidase activity in skeletal muscle cells. J Cell Physiol. 2008; 216: 796-804.
    • (2008) J Cell Physiol , vol.216 , pp. 796-804
    • Lambertucci, R.H.1    Hirabara, S.M.2    Silveira, L.R.3    Levada-Pires, A.C.4    Curi, R.5    Pithon-Curi, T.C.6
  • 20
    • 0028903933 scopus 로고
    • Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo
    • Zamzami N, Marchetti P, Castedo M et al. Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J Exp Med. 1995; 181: 1661-72.
    • (1995) J Exp Med , vol.181 , pp. 1661-1672
    • Zamzami, N.1    Marchetti, P.2    Castedo, M.3
  • 21
    • 0034027927 scopus 로고    scopus 로고
    • Oxidative stress induces caspase-independent retinal apoptosis in vitro
    • Carmody RJ, Cotter TG. Oxidative stress induces caspase-independent retinal apoptosis in vitro. Cell Death Differ. 2000; 7: 282-91.
    • (2000) Cell Death Differ , vol.7 , pp. 282-291
    • Carmody, R.J.1    Cotter, T.G.2
  • 22
    • 79952311179 scopus 로고    scopus 로고
    • Mitochondrial energy metabolism and redox responses to hypertriglyceridemia
    • Alberici LC, Vercesi AE, Oliveira HC. Mitochondrial energy metabolism and redox responses to hypertriglyceridemia. Bioenerg Biomembr. 2011; 43: 19-23.
    • (2011) Bioenerg Biomembr , vol.43 , pp. 19-23
    • Alberici, L.C.1    Vercesi, A.E.2    Oliveira, H.C.3
  • 23
    • 33746920337 scopus 로고    scopus 로고
    • Advanced glycation end products: Sparking the development of diabetic vascular injury
    • Goldin A, Beckman JA, Schmidt AM, Creager MA. Advanced glycation end products: Sparking the development of diabetic vascular injury. Circulation. 2006; 114: 597-605.
    • (2006) Circulation , vol.114 , pp. 597-605
    • Goldin, A.1    Beckman, J.A.2    Schmidt, A.M.3    Creager, M.A.4
  • 24
    • 0031773362 scopus 로고    scopus 로고
    • Advanced glycation endproducts inhibit prostacyclin production and induce plasminogen activator inhibitor-1 in human microvascular endothelial cells
    • Yamagishi S, Fujimori H, Yonekura H, Yamamoto Y, Yamamoto H. Advanced glycation endproducts inhibit prostacyclin production and induce plasminogen activator inhibitor-1 in human microvascular endothelial cells. Diabetologia. 1998; 41: 1435-41.
    • (1998) Diabetologia , vol.41 , pp. 1435-1441
    • Yamagishi, S.1    Fujimori, H.2    Yonekura, H.3    Yamamoto, Y.4    Yamamoto, H.5
  • 25
    • 0037119417 scopus 로고    scopus 로고
    • Involvement of c-Jun N-terminal kinase in oxidative stress-mediated suppression of insulin gene expression
    • Kaneto H, Xu G, Fujii N, Kim S, Bonner-Weir S, Weir GC. Involvement of c-Jun N-terminal kinase in oxidative stress-mediated suppression of insulin gene expression. Biol Chem. 2002; 277: 30010-18.
    • (2002) Biol Chem , vol.277 , pp. 30010-30018
    • Kaneto, H.1    Xu, G.2    Fujii, N.3    Kim, S.4    Bonner-Weir, S.5    Weir, G.C.6
  • 26
    • 33645860825 scopus 로고    scopus 로고
    • Reactive oxygen species have a causal role in multiple forms of insulin resistance
    • Houstis N, Rosen ED, Lander ES. Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature. 2006; 440: 944-8.
    • (2006) Nature , vol.440 , pp. 944-948
    • Houstis, N.1    Rosen, E.D.2    Lander, E.S.3
  • 27
    • 7044230885 scopus 로고    scopus 로고
    • Possible novel therapy for diabetes with cell-permeable JNK inhibitory peptide
    • Kaneto H, Nakatani Y, Miyatsuka T et al. Possible novel therapy for diabetes with cell-permeable JNK inhibitory peptide. Nat Med. 2004; 10: 1128-32.
    • (2004) Nat Med , vol.10 , pp. 1128-1132
    • Kaneto, H.1    Nakatani, Y.2    Miyatsuka, T.3
  • 28
    • 80655139907 scopus 로고    scopus 로고
    • Kakkalide and its metabolite irisolidone ameliorate carrageenan-induced inflammation in mice by inhibiting NF-κB pathway
    • Min SW, Park YJ, Kim DH. Kakkalide and its metabolite irisolidone ameliorate carrageenan-induced inflammation in mice by inhibiting NF-κB pathway. Inflammation. 2011; 34: 344-51.
    • (2011) Inflammation , vol.34 , pp. 344-351
    • Min, S.W.1    Park, Y.J.2    Kim, D.H.3
  • 29
    • 14544271905 scopus 로고    scopus 로고
    • Positive and negative regulation of insulin signaling through IRS-1 phosphorylation
    • Gual P, Le Marchand-Brustel Y, Tanti JF. Positive and negative regulation of insulin signaling through IRS-1 phosphorylation. Biochimie. 2005; 87: 99-109.
    • (2005) Biochimie , vol.87 , pp. 99-109
    • Gual, P.1    Le Marchand-Brustel, Y.2    Tanti, J.F.3
  • 30
    • 0037153158 scopus 로고    scopus 로고
    • A central role for JNK in obesity and insulin resistance
    • Hirosumi J, Tuncman G, Chang L et al. A central role for JNK in obesity and insulin resistance. Nature. 2002; 420: 333-6.
    • (2002) Nature , vol.420 , pp. 333-336
    • Hirosumi, J.1    Tuncman, G.2    Chang, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.