A novel F420-dependent anti-oxidant mechanism protects Mycobacterium tuberculosis against oxidative stress and bactericidal agents

Molecular Microbiology

Volumn 87, Issue 4, 2013, Pages 744-755

  Gurumurthy, Meera ^a,b,d   Rao, Martin ^a,e   Mukherjee, Tathagata ^c   Rao, Srinivasa P S ^a   Boshoff, Helena I ^c   Dick, Thomas ^a,d   Barry, Clifton E ^c   Manjunatha, Ujjini H ^a,b  

^a NOVARTIS INSTITUTE FOR TROPICAL DISEASES   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^e MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; BACTERIAL ENZYME; BACTERICIDE; CLOFAZIMINE; DEAZAFLAVIN DEPENDENT NITROREDUCTASE; F420 HYDROGEN DEPENDENT QUINONE REDUCTASE; ISONIAZID; MENADIONE; MOXIFLOXACIN; NITROREDUCTASE; OXIDOREDUCTASE; PLUMBAGIN; PROTEIN F420; SEMIQUINONE; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIOXIDANT ACTIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL IMMUNITY; BACTERIAL SURVIVAL; BACTERIUM MUTANT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; FBIC GENE; GENE INACTIVATION; MOLECULAR INTERACTION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

ANTI-BACTERIAL AGENTS; ANTIOXIDANTS; BACTERIAL PROTEINS; COENZYMES; MYCOBACTERIUM TUBERCULOSIS; NAD; NAD(P)H DEHYDROGENASE (QUINONE); OXIDATIVE STRESS;

BACTERIA (MICROORGANISMS); CORYNEBACTERINEAE; MYCOBACTERIUM TUBERCULOSIS;

EID: 84873467163     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/mmi.12127     Document Type: Article

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