Disruption of the MIG1 gene enhances lipid biosynthesis in the oleaginous yeast Yarrowia lipolytica ACA-DC 50109

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1831, Issue 4, 2013, Pages 675-682

  Wang, Zhi Peng ^a   Xu, Hong Mei ^a   Wang, Guang Yuan ^a   Chi, Zhe ^a   Chi, Zhen Ming ^a  

^a OCEAN UNIVERSITY OF CHINA   (China)

Author keywords

Gene expression; Lipid body; Oil accumulation; The oleaginous yeast; Yarrowia lipolytica

Indexed keywords

DEOXYGLUCOSE; FATTY ACID; MIG1 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; FUNGAL GENE; GENE DELETION; GENE DISRUPTION; GENE EXPRESSION; LIPID COMPOSITION; LIPID DEGRADATION; LIPID METABOLISM; LIPOGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; YARROWIA LIPOLYTICA;

FATTY ACIDS; FUNGAL PROTEINS; LIPID METABOLISM; YARROWIA;

YARROWIA LIPOLYTICA;

EID: 84873450128     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2012.12.010     Document Type: Article

References (25)

1. A. Beopoulos, J. Cescut, R. Haddouche, J.L. Uribelarrea, C. Molina-Jouve, and J.M. Nicaud Yarrowia lipolytica as a model for bio-oil production Prog. Lipid Res. 48 2009 375 387
2. M. Li, G.L. Liu, Z. Chi, and Z.M. Chi Single cell oil production from hydrolysate of cassava starch by marine-derived yeast Rhodotorula mucilaginosa TJY15a Biomass Bioenergy 4 2010 101 107
3. C.H. Zhao, W. Cui, X.Y. Liu, Z.M. Chi, and C. Madzak Expression of inulinase gene in the oleaginous yeast Yarrowia lipolytica and single cell oil production from inulin-containing materials Metab. Eng. 12 2010 510 517
4. A. Beopoulos, J.M. Nicaud, and C. Gaillardin An overview of lipid metabolism in yeasts and its impact on biotechnological processes Appl. Microbiol. Biotechnol. 90 2011 1193 1206
5. S. Papanikolaou, L. Muniglia, I. Chevalot, G. Aggelis, and I. Marc Yarrowia lipolytica as a potential producer of citric acid from raw glycerol J. Appl. Microbiol. 92 2002 737 744
6. J.M. Gancedo Yeast carbon catabolite repression Microbiol. Mol. Biol. Rev. 62 1998 334 361
7. G.L. Liu, D.S. Wang, L.F. Wang, S.F. Zhao, and Z.M. Chi Mig1 is involved in mycelial formation and expression of the genes encoding extracellular enzymes in Saccharomycopsis fibuligera A11 Fungal Genet. Biol. 48 2011 904 913
8. S. Papanikolaou, and G. Aggelis Selective uptake of fatty acids by the yeast Yarrowia lipolytica Eur. J. Lipid Sci. Technol. 105 2003 651 655
9. F. Wang, L.X. Yue, L. Wang, C. Madzak, J. Li, X.H. Wang, and Z.M. Chi Genetic modification of the marine-derived yeast Yarrowia lipolytica with high-protein content using a GPI-anchor-fusion expression system Biotechnol. Prog. 25 2009 1297 1303
10. J. Sambrook, E.F. Fritsch, and T. Maniatis Molecular Cloning: a Laboratory Manual second ed. 1989 Cold Spring Harbor Laboratory Press Beijing 367 370 (Chinese translated.)
11. J.M. Xuan, P. Fournier, and C. Gaillardin Cloning of the LYS5 gene encoding saccharopine dehydrogenase Curr. Genet. 14 1998 15 21
12. J. Folch, M. Lees, and J. Slane-Stanley A simple method for the isolation and purification of total lipids from animal tissues J. Biol. Chem. 226 1957 497 509
13. K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using realtime quantitative PCR and the 2-DDCt method Methods 25 2001 402 408
14. C.F. Wu, and M. Hamada Experiments Planning, Analysis and Parameter Design Optimization 2000 John Wiley and Sons New York 23 34
15. J.O. Westholm, N. Nordberg, E. Murén, A. Ameur, J. Komorowski, and H. Ronne Combinatorial control of gene expression by the three yeast repressors Mig1, Mig2 and Mig3 BMC Genomics 9 2008 601 607
16. C.L. Flores, and C. Gancedo Yarrowia lipolytica mutants devoid of pyruvate carboxylase activity show an unusual growth phenotype Eukaryot. Cell 4 2005 356 364
17. K. Athenstaedt Isolation and characterization of lipid particles from yeast K.N. Timmis, Handbook of Hydrocarbon and Lipid Microbiology 2010 Springer-Verlag Berlin Heidelberg 4224 4229
18. O.G. Stasyk, T. van Zutphen, H.A. Kang, O.V. Stasyk, M. Veenhuis, and A.A. Sibirny The role of Hansenula polymorpha MIG1 homologues in catabolite repression and pexophagy FEMS Yeast Res. 7 2007 1103 1113
19. Z.M. Chi, J.F. Li, X.H. Wang, and S.M. Yao Inositol and phosphatidylinositol mediated glucose derepression, gene expression and invertase secretion in yeasts Acta Biochim. Biophys. Sin. 36 2004 443 449
20. A. Beopoulos, Z. Mrozova, F. Thevenieau, M.T. Le Dall, I. Hapala, S. Papanikolaou, T. Chardot, and J.M. Nicaud Control of lipid accumulation in the yeast Yarrowia lipolytica Appl. Environ. Microbiol. 74 2008 7779 7789
21. K. Athenstaedt, P. Jolivet, C. Boulard, M. Zivy, L. Negroni, J.M. Nicaud, and T. Chardot Lipid particle composition of the yeast Yarrowia lipolytica depends on the carbon source Proteomics 6 2006 1450 1459
22. Q. Wang, F.J. Guo, Y.J. Rong, and Z.M. Chi Lipid production from hydrolysate of cassava starch by Rhodosporidium toruloides 21167 for biodiesel making Renew. Energy 46 2012 164 168
23. X.Y. Liu, Z. Chi, G.L. Liu, C. Madzak, and Z.M. Chi Both decrease in ACL1 gene expression and increase in ICL1 gene expression in marine-derived yeast Yarrowia lipolytica expressing INU1 gene enhance citric acid production from inulin Mar. Biotechnol. 2012 10.1007/s10126-012-9452-5
24. Y. Li, Z. Zhao, and F. Bai High-density cultivation of oleaginous yeast Rhodosporidium toruloides Y4 in fed-batch culture Enzyme Microb. Technol. 41 2007 312 317
25. M. Hassan, P.J. Blanc, L.M. Granger, A. Pareilleux, and G. Goma Influence of nitrogen and iron limitations on lipid production by Cryptococcus curvatus grown in batch and fed-batch culture Proc. Biochem. 31 1996 355 361