Both Decrease in ACL1 Gene Expression and Increase in ICL1 Gene Expression in Marine-Derived Yeast Yarrowia lipolytica Expressing INU1 Gene Enhance Citric Acid Production from Inulin

Marine Biotechnology

Volumn 15, Issue 1, 2013, Pages 26-36

  Liu, Xiao Yan ^a   Chi, Zhe ^a   Liu, Guang Lei ^a   Madzak, Catherine ^a   Chi, Zhen Ming ^a  

^a OCEAN UNIVERSITY OF CHINA   (China)

Author keywords

ATP citrate lyase; Citric acid; Inulin; Iso citrate lyase; Yarrowia lipolytica

Indexed keywords

ACID PRODUCTION; ATP-CITRATE LYASE; COPY NUMBER; INULIN; INULINASE; ISO-CITRATE LYASE; LIPID CONTENT; LYASE ACTIVITY; REDUCING SUGARS; YARROWIA LIPOLYTICA;

GENE EXPRESSION; POLYSACCHARIDES; SUGARS; YEAST;

CITRIC ACID;

ADENOSINE TRIPHOSPHATE CITRATE LYASE; CITRIC ACID; FUNGAL PROTEIN; INULIN; ISOCITRATE LYASE; PRIMER DNA;

CITRIC ACID; ENZYME ACTIVITY; GENE EXPRESSION; LIPID; PROTEIN; RECOMBINATION; SUGAR; TRANSFORMATION; YEAST;

ARTICLE; BIOREACTOR; BIOSYNTHESIS; ESCHERICHIA COLI; FERMENTATION; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENE VECTOR; GENETICS; METABOLISM; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; YARROWIA;

ATP CITRATE (PRO-S)-LYASE; BIOREACTORS; BIOSYNTHETIC PATHWAYS; CITRIC ACID; DNA PRIMERS; ESCHERICHIA COLI; FERMENTATION; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GENE KNOCKOUT TECHNIQUES; GENETIC VECTORS; INULIN; ISOCITRATE LYASE; REAL-TIME POLYMERASE CHAIN REACTION; YARROWIA;

YARROWIA LIPOLYTICA;

EID: 84871661211     PISSN: 14362228     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10126-012-9452-5     Document Type: Article

References (34)

1. Alvarez-Vasquez F, González-Alcón C, Torres NV (2000) Metabolism of citric acid production by Aspergillus niger: model definition, steady-state analysis and constrained optimization of citric acid production rate. Biotechnol Bioeng 70: 82-108.
2. Antonucci S, Bravi M, Bubbico R, Michele AD, Verdone N (2001) Selectivity in citric acid production by Yarrowia lipolytica. Enzy Microb Technol 28: 189-195.
3. Arzumanov TE, Shishkanova NV, Finogenova TF (2000) Biosynthesis of citric acid by Yarrowia lipolytica repeat-batch culture on ethanol. Appl Microbiol Biotechnol 53: 525-529.
4. Camp BJ, Farmer L (1967) A rapid spectrophotometric method for the determination of citric acid in blood. Clin Chem 13: 501-505.
5. Chi ZM, Liu J, Zhang W (2001) Trehalose accumulation from soluble starch by Saccharomycopsis fibuligera sdu. Enzy Microb Technol 28: 240-245.
6. Chi ZM, Zhang T, Cao TS, Liu XY, Cui W, Zhao CH (2011) Biotechnological potential of inulin for bioprocesses. Biores Technol 102: 4295-4303.
7. Crolla A, Kennedy KJ (2001) Optimization of citric acid production from Candida lipolytica Y-1095 using n-paraffin. J Biotechnol 89: 27-40.
8. Darvishi F, Nahvi I, Zarkesh-Esfahani H, Momenbeik F (2009) Effect of plant oils upon lipase and citric acid production in Yarrowia lipolytica yeast. J Biomed Biotechnol 56: 29-43.
9. de Jongh WA, Nielsen J (2008) Enhanced citrate production through gene insertion in Aspergillus niger. Metab Eng 10: 87-96.
10. Folch J, Lees M, Slane-Stanley JA (1957) A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226: 497-509.
11. Förster A, Aurich A, Mauersberger S, Barth G (2007) Citric acid production from sucrose using a recombinant strain of the yeast Yarrowia lipolytica. Appl Microbiol Biotechnol 75: 1409-1417.
12. Gong F, Sheng J, Chi ZM, Li J (2007) Inulinase production by a marine yeast Pichia guilliermondii and inulin hydrolysis by the crude inulinase. J Ind Microbiol Biotechnol 34: 179-185.
13. Imandi SB, Bandaru VVR, Somalanka SR, Garapati HR (2007) Optimization of medium constituents for the production of citric acid from byproduct glycerol using Doehlert experimental design. Enzyme Microb Technol 40: 1367-13.
14. Jolivalt C, Madzak C, Brault A, Caminade E, Malosse C, Mougin C (2005) Expression of laccase IIIb from the white-rot fungus Trametes versicolor in the yeast Yarrowia lipolytica for environmental applications. Appl Microbiol Biotechnol 66: 450-456.
15. Kamzolova SV, Finogenova TV, Morgunov IG (2008) Microbiological production of citric and isocitric acids from sunflower oil. Food Technol Biotechnol 46: 51-59.
16. + transformants. Biores Technol 102: 6982-6989.
17. Lipmann F, Tuttle LC (1945) A specific micromethod for the determination of acyl phosphates. J Biol Chem 159: 21-28.
18. Liu XY, Chi Z, Liu GL, Wang F, Madzak C, Chi ZM (2010) Inulin hydrolysis and citric acid production from inulin using the surface-engineered Yarrowia lipolytica displaying inulinase. Metab Eng 12: 469-476.
19. Liu GL, Wang DS, Wang LF, Zhao SF, Chi ZM (2011) Mig1 is involved in mycelial formation and expression of the genes encoding extracellular enzymes in Saccharomycopsis fibuligera A11. Fung Genet Biol 48: 904-913.
20. Lotfy WA, Ghanem KM, El-Helow ER (2007) Citric acid production by a novel Aspergillus niger isolate: I. Mutagenesis and cost reduction studies. Biores Technol 98: 3464-3469.
21. Papagianni M (2007) Advances in citric acid fermentation by Aspergillus niger: biochemical aspects, membrane transport and modeling. Biotechnol Adv 25: 244-263.
22. Papanikolaou S, Fakas S, Fick M, Chevalot I, Galiotou-Panayotou M, Komaitis M, Marc I, Aggelis G (2008a) Biotechnological valorisation of raw glycerol discharged after bio-diesel (fatty acid methyl esters) manufacturing process: production of 1, 3-propanediol, citric acid and single cell oil. Biom Bioenerg 32: 60-71.
23. Papanikolaou S, Galiotou-Panayotou M, Fakas S, Komaitis M, Aggelis G (2008b) Citric acid production by Yarrowia lipolytica cultivated on olive-mill wastewater-based media. Biores Technol 99: 2419-2428.
24. Rywinska A, Juszczyk P, Wojtatowicz M, Rymowicz W (2011) Chemostat study of citric acid production from glycerol by Yarrowia lipolytica. J Biotechnol 152: 54-57.
25. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Beijing, pp. 367-370 (Chinese translating ed.).
26. Slightom JL, Metzger BT, Luu HT, Elhammer AP (2009) Cloning and molecular characterization of the gene encoding the Aureobasidin A biosynthesis complex in Aureobasidium pullulans BP-1938. Gene 431: 67-79.
27. Spiro RG (1966) Analysis of sugars found in glycoproteins. Meth Enzymol 8: 3-26.
28. Venter T, Kock JIF, Botes PJ, Smit MS, Hugo A, Joseph M (2004) Acetate enhances citric acid production by Yarrowia lipolytica when grown on sunflower oil. Syste Appl Microbiol 27: 135-138.
29. Wang F, Yue LX, Wang L, Madzak C, Li J, Wang XH, Chi ZM (2009) Genetic modification of the marine-derived yeast Yarrowia lipolytica with high-protein content using a GPI-anchor-fusion expression system. Biotechnol Prog 25: 1297-1303.
30. Watanabe T, Suzuki A, Nakagawa H, Kirimura K, Usami S (1998) Citric acid production from cellulose hydrolysate by a 2-deoxy-D-glucose-resistant mutant strain of Aspergillus niger. Biores Technol 66: 271-274.
31. Xuan JM, Fournier P, Gaillardin C (1988) Cloning of the LYS5 gene encoding saccharopine dehydrogenase. Curr Genet 14: 15-21.
32. Yue LX, Chi ZM, Wang L, Liu J, Madzak C, Li J (2008) Construction of a new plasmid for surface display on cells of Yarrowia lipolytica. J Microbiol Meth 72: 116-123.
33. Zhang BZ (1988) Determination of isocitrate lyase activity in seeds. Plant Physiol Comm 3: 68-70.
34. Zhao CH, Cui W, Liu XY, Chi ZM, Madzak C (2010) Expression of inulinase gene in the oleaginous yeast Yarrowia lipolytica and single cell oil production from inulin-containing materials. Metab Eng 12: 510-551.