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Volumn 26, Issue 11, 2012, Pages 983-991

Clobazam: In patients with Lennox-Gastaut syndrome

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ANTICONVULSIVE AGENT; CAFFEINE; CARBAMAZEPINE; CLOBAZAM; CONTRACEPTIVE AGENT; DEXTROMETHORPHAN; DIAZEPAM; ESLICARBAZEPINE; FELBAMATE; FLUCONAZOLE; FLUVOXAMINE; KETOCONAZOLE; LAMOTRIGINE; MIDAZOLAM; NORCLOBAZAM; OMEPRAZOLE; OXCARBAZEPINE; PERAMPANEL; PHENOBARBITAL; PHENYTOIN; PLACEBO; TICLOPIDINE; TOLBUTAMIDE; UNCLASSIFIED DRUG; URBANOL;

EID: 84873435471     PISSN: 11727047     EISSN: 11791934     Source Type: Journal    
DOI: 10.1007/s40263-012-0007-0     Document Type: Article
Times cited : (5)

References (29)
  • 1
    • 80052575585 scopus 로고    scopus 로고
    • All children who experience epileptic falls do not necessarily have Lennox-Gastaut syndrome. but many do
    • 21669558
    • Arzimanoglou A, Resnick T. All children who experience epileptic falls do not necessarily have Lennox-Gastaut syndrome. but many do. Epileptic Disord. 2011;13(Suppl 1):S3-13.
    • (2011) Epileptic Disord , vol.13 , Issue.SUPPL. 1
    • Arzimanoglou, A.1    Resnick, T.2
  • 2
    • 57249087382 scopus 로고    scopus 로고
    • Lennox-Gastaut syndrome: A consensus approach on diagnosis, assessment, management, and trial methodology
    • 19081517 10.1016/S1474-4422(08)70292-8
    • Arzimanoglou A, French J, Blume WT, et al. Lennox-Gastaut syndrome: a consensus approach on diagnosis, assessment, management, and trial methodology. Lancet Neurol. 2009;8(1):82-93.
    • (2009) Lancet Neurol , vol.8 , Issue.1 , pp. 82-93
    • Arzimanoglou, A.1    French, J.2    Blume, W.T.3
  • 3
    • 60249089708 scopus 로고    scopus 로고
    • Treatment of Lennox-Gastaut syndrome: Overview and recent findings
    • 10.2147/NDT.S1668
    • van Rijckevorsel K. Treatment of Lennox-Gastaut syndrome: overview and recent findings. Neuropsychiatri Dis Treat. 2008;4(6):1001-19.
    • (2008) Neuropsychiatri Dis Treat , vol.4 , Issue.6 , pp. 1001-1019
    • Van Rijckevorsel, K.1
  • 4
    • 0034098323 scopus 로고    scopus 로고
    • A risk-benefit assessment of therapies for Lennox-Gastaut syndrome
    • 10877040 10.2165/00002018-200022060-00005 1:CAS:528:DC%2BD3cXkslygsrc%3D
    • Schmidt D, Bourgeois B. A risk-benefit assessment of therapies for Lennox-Gastaut syndrome. Drug Saf. 2000;22(6):467-77.
    • (2000) Drug Saf , vol.22 , Issue.6 , pp. 467-477
    • Schmidt, D.1    Bourgeois, B.2
  • 6
    • 79960934316 scopus 로고    scopus 로고
    • Rational approach to treatment options for Lennox-Gastaut syndrome
    • 21790561 10.1111/j.1528-1167.2011.03178.x
    • Montouris GD. Rational approach to treatment options for Lennox-Gastaut syndrome. Epilepsia. 2011;52(Suppl 5):10-20.
    • (2011) Epilepsia , vol.52 , Issue.SUPPL. 5 , pp. 10-20
    • Montouris, G.D.1
  • 7
    • 79952170654 scopus 로고    scopus 로고
    • Management of seizures in Lennox-Gastaut syndrome
    • 21351810 10.2165/11536940-000000000-00000
    • Crumrine PK. Management of seizures in Lennox-Gastaut syndrome. Paediatr Drugs. 2011;13(2):107-18.
    • (2011) Paediatr Drugs , vol.13 , Issue.2 , pp. 107-118
    • Crumrine, P.K.1
  • 8
    • 69549112867 scopus 로고    scopus 로고
    • Impact of Lennox-Gastaut Syndrome (LGS) on health-related quality of life (HRQL) of patients and caregivers: Literature review
    • 19592271 10.1016/j.seizure.2009.06.005
    • Gallop K, Wild D, Nixon A, et al. Impact of Lennox-Gastaut Syndrome (LGS) on health-related quality of life (HRQL) of patients and caregivers: literature review. Seizure. 2009;18(8):554-8.
    • (2009) Seizure , vol.18 , Issue.8 , pp. 554-558
    • Gallop, K.1    Wild, D.2    Nixon, A.3
  • 9
    • 55949109998 scopus 로고    scopus 로고
    • Benzodiazepines in epilepsy: Pharmacology and pharmacokinetics
    • 18384456 10.1111/j.1600-0404.2008.01004.x 1:CAS:528:DC%2BD1cXhtVajtbzO
    • Riss J, Cloyd J, Gates J, et al. Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008;118(2):69-86.
    • (2008) Acta Neurol Scand , vol.118 , Issue.2 , pp. 69-86
    • Riss, J.1    Cloyd, J.2    Gates, J.3
  • 10
    • 84856905846 scopus 로고    scopus 로고
    • GABA(A) receptor physiology and its relationship to the mechanism of action of the 1,5-benzodiazepine clobazam
    • 22145708 10.2165/11599020-000000000-00000 1:CAS:528:DC%2BC38XnsVKjsro%3D
    • Sankar R. GABA(A) receptor physiology and its relationship to the mechanism of action of the 1,5-benzodiazepine clobazam. CNS Drugs. 2012;26(3):229-44.
    • (2012) CNS Drugs , vol.26 , Issue.3 , pp. 229-244
    • Sankar, R.1
  • 13
    • 33846194260 scopus 로고    scopus 로고
    • Clobazam
    • 17199029 10.1016/j.nurt.2006.11.002 1:CAS:528:DC%2BD2sXisFaksbs%3D
    • Ng Y-T, Collins SD. Clobazam. Neurotherapeutics. 2007;4(1):138-44.
    • (2007) Neurotherapeutics , vol.4 , Issue.1 , pp. 138-144
    • Ng, Y.-T.1    Collins, S.D.2
  • 15
    • 84872867078 scopus 로고    scopus 로고
    • Clobazam and its active metabolite, N-desmethylclobazam, are high-affinity ligands for the benzodiazepine sites of GABAA receptors
    • [abstract no. P05.086]
    • Jensen HS, Ebert B. Clobazam and its active metabolite, N-desmethylclobazam, are high-affinity ligands for the benzodiazepine sites of GABAA receptors [abstract no. P05.086]. Neurology. 2012;78 Suppl 1.
    • (2012) Neurology , vol.78 , Issue.SUPPL.. 1
    • Jensen, H.S.1    Ebert, B.2
  • 16
    • 33746887419 scopus 로고    scopus 로고
    • Experimental and clinical evidence of loss of effect (tolerance) during prolonged treatment with antiepileptic drugs
    • 16922870 10.1111/j.1528-1167.2006.00607.x
    • Löscher W, Schmidt D. Experimental and clinical evidence of loss of effect (tolerance) during prolonged treatment with antiepileptic drugs. Epilepsia. 2006;47(8):1253-84.
    • (2006) Epilepsia , vol.47 , Issue.8 , pp. 1253-1284
    • Löscher, W.1    Schmidt, D.2
  • 17
    • 17144474677 scopus 로고    scopus 로고
    • Clobazam has equivalent efficacy to carbamazepine and phenytoin as monotherapy for childhood epilepsy
    • Canadian Study Group for Childhood Epilepsy 10.1111/j.1528-1157.1998. tb01444.x
    • Canadian Study Group for Childhood Epilepsy. Clobazam has equivalent efficacy to carbamazepine and phenytoin as monotherapy for childhood epilepsy. Epilepsia. 1998;39(9):952-9.
    • (1998) Epilepsia , vol.39 , Issue.9 , pp. 952-959
  • 18
    • 84873417177 scopus 로고    scopus 로고
    • Demographic factors and concomitant antiepileptic drugs have no effect on the pharmacodynamics of perampanel
    • [abstract no. P06.127]
    • Hussein Z, Ferry J, Krauss G, et al. Demographic factors and concomitant antiepileptic drugs have no effect on the pharmacodynamics of perampanel [abstract no. P06.127]. Neurology. 2012;78 Suppl 1.
    • (2012) Neurology , vol.78 , Issue.SUPPL.. 1
    • Hussein, Z.1    Ferry, J.2    Krauss, G.3
  • 19
    • 83455178806 scopus 로고    scopus 로고
    • Pharmacokinetics, drug interactions and exposure-response relationship of eslicarbazepine acetate in adult patients with partial-onset seizures: Population pharmacokinetic and pharmacokinetic/pharmacodynamic analyses
    • 22171585 10.2165/11596290-000000000-00000
    • Falcão A, Fuseau E, Nunes T, et al. Pharmacokinetics, drug interactions and exposure-response relationship of eslicarbazepine acetate in adult patients with partial-onset seizures: population pharmacokinetic and pharmacokinetic/pharmacodynamic analyses. CNS Drugs. 2012;26(1):79-91.
    • (2012) CNS Drugs , vol.26 , Issue.1 , pp. 79-91
    • Falcão, A.1    Fuseau, E.2    Nunes, T.3
  • 20
    • 84864096509 scopus 로고    scopus 로고
    • Pharmacokinetic drug interactions between clobazam and drugs metabolized by cytochrome P450 isoenzymes
    • 22422635 10.1002/j.1875-9114.2012.01028.x 1:CAS:528:DC%2BC38XntVyms7w%3D
    • Walzer M, Bekersky I, Blum RA, et al. Pharmacokinetic drug interactions between clobazam and drugs metabolized by cytochrome P450 isoenzymes. Pharmacotherapy. 2012;32(4):340-53.
    • (2012) Pharmacotherapy , vol.32 , Issue.4 , pp. 340-353
    • Walzer, M.1    Bekersky, I.2    Blum, R.A.3
  • 21
    • 0018386980 scopus 로고
    • Kinetics and metabolism of clobazam in animals and man
    • 35204 10.1111/j.1365-2125.1979.tb04664.x
    • Volz M, Christ O, Kellner HM, et al. Kinetics and metabolism of clobazam in animals and man. Br J Clin Pharmacol. 1979;7(Suppl 1):41S-50S.
    • (1979) Br J Clin Pharmacol , vol.7 , Issue.SUPPL. 1
    • Volz, M.1    Christ, O.2    Kellner, H.M.3
  • 22
    • 0018383221 scopus 로고
    • Pharmacokinetics of single and multiple doses of clobazam in humans
    • 35205 10.1111/j.1365-2125.1979.tb04665.x
    • Rupp W, Badian M, Christ O, et al. Pharmacokinetics of single and multiple doses of clobazam in humans. Br J Clin Pharmacol. 1979;7(Suppl 1):51S-7S.
    • (1979) Br J Clin Pharmacol , vol.7 , Issue.SUPPL. 1
    • Rupp, W.1    Badian, M.2    Christ, O.3
  • 23
    • 6944252142 scopus 로고    scopus 로고
    • In vitro characterization of clobazam metabolism by recombinant cytochrome P450 enzymes: Importance of CYP2C19
    • 15483195 1:CAS:528:DC%2BD2cXovFCktbk%3D
    • Giraud C, Tran A, Rey E, et al. In vitro characterization of clobazam metabolism by recombinant cytochrome P450 enzymes: importance of CYP2C19. Drug Metab Dispos. 2004;32(11):1279-86.
    • (2004) Drug Metab Dispos , vol.32 , Issue.11 , pp. 1279-1286
    • Giraud, C.1    Tran, A.2    Rey, E.3
  • 24
    • 84873473235 scopus 로고    scopus 로고
    • Effects of concomitant lamotrigine or valproate therapy on clobazam for Lennox-Gastaut syndrome: Subanalyses of the CONTAIN trial
    • [abstract no. P06.120]
    • Renfroe J, Conry J, Ng Y-T, et al. Effects of concomitant lamotrigine or valproate therapy on clobazam for Lennox-Gastaut syndrome: subanalyses of the CONTAIN trial [abstract no. P06.120]. Neurology 2012;78 Suppl 1.
    • (2012) Neurology , vol.78 , Issue.SUPPL.. 1
    • Renfroe, J.1    Conry, J.2    Ng, Y.-T.3
  • 25
    • 84873423046 scopus 로고    scopus 로고
    • Clobazam is efficacious for drop attacks in patients with Lennox-Gastaut syndrome across the age spectrum: Subgroup analysis of the CONTAIN trial
    • [abstract no. P06.096]
    • Mitchell W, Conry J, Ng Y-T, et al. Clobazam is efficacious for drop attacks in patients with Lennox-Gastaut syndrome across the age spectrum: subgroup analysis of the CONTAIN trial [abstract no. P06.096]. Neurology 2012;78 Suppl 1.
    • (2012) Neurology , vol.78 , Issue.SUPPL.. 1
    • Mitchell, W.1    Conry, J.2    Ng, Y.-T.3
  • 26
    • 82955235708 scopus 로고    scopus 로고
    • Randomized, phase III study results of clobazam in Lennox-Gastaut syndrome
    • Accessed 24 Jul 2012
    • Ng Y-T, Conry JA, Drummond R, et al. Randomized, phase III study results of clobazam in Lennox-Gastaut syndrome. Neurology 2011; 77 (15): 1473-81. http://www.neurology.com. Accessed 24 Jul 2012.
    • (2011) Neurology , vol.77 , Issue.15 , pp. 1473-1481
    • Ng, Y.-T.1    Conry, J.A.2    Drummond, R.3
  • 27
    • 65549123702 scopus 로고    scopus 로고
    • Clobazam in the treatment of Lennox-Gastaut syndrome
    • 19170737 10.1111/j.1528-1167.2008.01935.x 1:CAS:528:DC%2BD1MXms1Skt7o%3D
    • Conry JA, Ng Y-T, Paolicchi JM, et al. Clobazam in the treatment of Lennox-Gastaut syndrome. Epilepsia. 2009;50(5):1158-66.
    • (2009) Epilepsia , vol.50 , Issue.5 , pp. 1158-1166
    • Conry, J.A.1    Ng, Y.-T.2    Paolicchi, J.M.3
  • 28
    • 85081775983 scopus 로고    scopus 로고
    • Long-term safety and efficacy of clobazam for Lennox Gastaut syndrome (LGS): 2-year results of an open label extension (OLE) study [abstract no. 14]
    • Ng Y-T, Conry JA, Paolicchi JM, et al. Long-term safety and efficacy of clobazam for Lennox Gastaut syndrome (LGS): 2-year results of an open label extension (OLE) study [abstract no. 14]. Ann Neurol. 2011;70(Suppl 1):S15-140.
    • (2011) Ann Neurol , vol.70 , Issue.SUPPL. 1
    • Ng, Y.-T.1    Conry, J.A.2    Paolicchi, J.M.3
  • 29
    • 85081782289 scopus 로고    scopus 로고
    • Withdrawal-related adverse events from clinical trials of clobazam in Lennox-Gastaut syndrome (LGS)
    • [abstract no. P06.106]
    • Tolbert D, Harris S, Bekersky I, et al. Withdrawal-related adverse events from clinical trials of clobazam in Lennox-Gastaut syndrome (LGS) [abstract no. P06.106]. Neurology 2012; 78 (Suppl 1).
    • (2012) Neurology , vol.78 , Issue.SUPPL.. 1
    • Tolbert, D.1    Harris, S.2    Bekersky, I.3


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