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Volumn 26, Issue 1, 2012, Pages 79-91

Pharmacokinetics, drug interactions and exposure-response relationship of eslicarbazepine acetate in adult patients with partial-onset seizures: Population pharmacokinetic and pharmacokinetic pharmacodynamic analyses

Author keywords

Antiepileptic drugs; Epilepsy; Eslicarbazepine acetate

Indexed keywords

BARBITURIC ACID DERIVATIVE; CARBAMAZEPINE; CLOBAZAM; CREATININE; ESLICARBAZEPINE ACETATE; ETIRACETAM; GABAPENTIN; LAMOTRIGINE; PHENYTOIN; TOPIRAMATE; VALPROIC ACID;

EID: 83455178806     PISSN: 11727047     EISSN: 11791934     Source Type: Journal    
DOI: 10.2165/11596290-000000000-00000     Document Type: Article
Times cited : (30)

References (15)
  • 1
    • 70349969112 scopus 로고    scopus 로고
    • Eslicarbazepine acetate
    • Shorvon S, Perucca E, Engel J, editors 3rd ed. Oxford: Blackwell Publishing
    • Almeida L, Bialer M, Soares-da-Silva P. Eslicarbazepine acetate. In: Shorvon S, Perucca E, Engel J, editors. The treatment of epilepsy. 3rd ed. Oxford: Blackwell Publishing, 2009: 485-98
    • (2009) The Treatment of Epilepsy , pp. 485-98
    • Almeida, L.1    Bialer, M.2    Soares-Da-Silva, P.3
  • 2
    • 43049177758 scopus 로고    scopus 로고
    • Pharmacokinetics of eslicarbazepine acetate in patients with moderate hepatic impairment
    • Mar
    • Almeida L, Potgieter JH, Maia J, et al. Pharmacokinetics of eslicarbazepine acetate in patients with moderate hepatic impairment. Eur J Clin Pharmacol 2008 Mar; 64 (3): 267-73
    • (2008) Eur J Clin Pharmacol , vol.64 , Issue.3 , pp. 267-73
    • Almeida, L.1    Potgieter, J.H.2    Maia, J.3
  • 4
    • 33847611166 scopus 로고    scopus 로고
    • Eslicarbazepine acetate: A double-blind, add-on, placebo-controlled exploratory trial in adult patients with partial-onset seizures
    • DOI 10.1111/j.1528-1167.2007.00984.x
    • Elger C, Bialer M, Cramer JA, et al. Eslicarbazepine acetate: a double-blind, add-on, placebo-controlled exploratory trial in adult patients with partial-onset seizures. Epilepsia 2007 Mar; 48 (3): 497-504 (Pubitemid 46365199)
    • (2007) Epilepsia , vol.48 , Issue.3 , pp. 497-504
    • Elger, C.1    Bialer, M.2    Cramer, J.A.3    Maia, J.4    Almeida, L.5    Soares-Da-Silva, P.6
  • 5
    • 61849168486 scopus 로고    scopus 로고
    • Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures: A randomized, double-blind, placebo-controlled, parallel-group phase III study
    • Mar
    • Elger C, Halasz P, Maia J, et al. Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures: a randomized, double-blind, placebo-controlled, parallel-group phase III study. Epilepsia 2009 Mar; 50 (3): 454-63
    • (2009) Epilepsia , vol.50 , Issue.3 , pp. 454-63
    • Elger, C.1    Halasz, P.2    Maia, J.3
  • 6
    • 77951297857 scopus 로고    scopus 로고
    • Eslicarbazepine acetate as adjunctive therapy in adult patients with partial epilepsy
    • Mar 16
    • Ben-Menachem E, Gabbai AA, Hufnagel A, et al. Eslicarbazepine acetate as adjunctive therapy in adult patients with partial epilepsy. Epilepsy Res 2010 Mar 16; 89 (2-3): 278-85
    • (2010) Epilepsy Res , vol.89 , Issue.2-3 , pp. 278-85
    • Ben-Menachem, E.1    Gabbai, A.A.2    Hufnagel, A.3
  • 7
    • 70349972675 scopus 로고    scopus 로고
    • Efficacy and safety of 800 and 1200 mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures
    • Nov
    • Gil-Nagel A, Lopes-Lima J, Almeida L, et al. Efficacy and safety of 800 and 1200 mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures. Acta Neurol Scand 2009 Nov; 120 (5): 281-7
    • (2009) Acta Neurol Scand , vol.120 , Issue.5 , pp. 281-7
    • Gil-Nagel, A.1    Lopes-Lima, J.2    Almeida, L.3
  • 8
    • 78649248897 scopus 로고    scopus 로고
    • Long-term efficacy and safety of eslicarbazepine acetate: Results of a 1-year open-label extension study in partial-onset seizures in adults with epilepsy
    • Oct
    • Halasz P, Cramer JA, Hodoba D, et al. Long-term efficacy and safety of eslicarbazepine acetate: results of a 1-year open-label extension study in partial-onset seizures in adults with epilepsy. Epilepsia 2010 Oct; 51 (10): 1963-9
    • (2010) Epilepsia , vol.51 , Issue.10 , pp. 1963-9
    • Halasz, P.1    Cramer, J.A.2    Hodoba, D.3
  • 10
    • 0003747347 scopus 로고    scopus 로고
    • San Francisco (CA): University of California
    • Beal S, Sheiner L. NONMEM users guide. San Francisco (CA): University of California, 1998
    • (1998) NONMEM Users Guide
    • Beal, S.1    Sheiner, L.2
  • 11
    • 0016916438 scopus 로고
    • Prediction of creatinine clearance from serum creatinine
    • Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976; 16 (1): 31-41
    • (1976) Nephron , vol.16 , Issue.1 , pp. 31-41
    • Cockcroft, D.W.1    Gault, M.H.2
  • 12
    • 0141516469 scopus 로고    scopus 로고
    • Oxcarbazepine: Chemistry, biotransformation and pharmacokinetics
    • Levy RH, Mattson R, Meldrum BS, et al., editors 5th ed Philadelphia (PA):Lippincott
    • Bialer M. Oxcarbazepine: chemistry, biotransformation and pharmacokinetics. In: Levy RH, Mattson R, Meldrum BS, et al., editors. Antiepileptic drugs. 5th ed. Philadelphia (PA): Lippincott, 2002: 459-65
    • (2002) Antiepileptic Drugs , pp. 459-65
    • Bialer, M.1
  • 13
    • 79956136111 scopus 로고    scopus 로고
    • Pharmacokinetics of the monohydroxy derivative of oxcarbazepine and its enantiomers after a single intravenous dose given as racemate compared with a single oral dose of oxcarbazepine
    • Jun
    • Flesch G, Czendlik C, Renard D, et al. Pharmacokinetics of the monohydroxy derivative of oxcarbazepine and its enantiomers after a single intravenous dose given as racemate compared with a single oral dose of oxcarbazepine. Drug Metab Dispos 2011 Jun; 39 (6): 1103-10
    • (2011) Drug Metab Dispos , vol.39 , Issue.6 , pp. 1103-10
    • Flesch, G.1    Czendlik, C.2    Renard, D.3
  • 14
    • 77749279921 scopus 로고    scopus 로고
    • Pharmacokinetic interaction study between eslicarbazepine acetate and lamotrigine in healthy subjects
    • Apr
    • Almeida L, Nunes T, Sicard E, et al. Pharmacokinetic interaction study between eslicarbazepine acetate and lamotrigine in healthy subjects. Acta Neurol Scand 2010 Apr; 121 (4): 257-64
    • (2010) Acta Neurol Scand , vol.121 , Issue.4 , pp. 257-64
    • Almeida, L.1    Nunes, T.2    Sicard, E.3
  • 15
    • 77952477242 scopus 로고    scopus 로고
    • Pharmacokinetic interaction study between eslicarbazepine acetate and topiramate in healthy subjects
    • Jun
    • Nunes T, Sicard E, Almeida L, et al. Pharmacokinetic interaction study between eslicarbazepine acetate and topiramate in healthy subjects. Curr Med Res Opin 2010 Jun; 26 (6): 1355-62
    • (2010) Curr Med Res Opin , vol.26 , Issue.6 , pp. 1355-62
    • Nunes, T.1    Sicard, E.2    Almeida, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.