Pharmacokinetics, drug interactions and exposure-response relationship of eslicarbazepine acetate in adult patients with partial-onset seizures: Population pharmacokinetic and pharmacokinetic pharmacodynamic analyses

CNS Drugs

Volumn 26, Issue 1, 2012, Pages 79-91

  Falcão, Amilcar ^a,b   Fuseau, Eliane ^c   Nunes, Teresa ^d   Almeida, Luis ^e   Soares Da Silva, Patricio ^d,f  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b Biocant   (Portugal)

^c EMF Consulting   (France)

^d DEPARTMENT OF RESEARCH AND DEVELOPMENT   (Portugal)

^e UNIVERSITY OF AVEIRO   (Portugal)

^f University of Porto   (Portugal)

Author keywords

Antiepileptic drugs; Epilepsy; Eslicarbazepine acetate

Indexed keywords

BARBITURIC ACID DERIVATIVE; CARBAMAZEPINE; CLOBAZAM; CREATININE; ESLICARBAZEPINE ACETATE; ETIRACETAM; GABAPENTIN; LAMOTRIGINE; PHENYTOIN; TOPIRAMATE; VALPROIC ACID;

AGE DISTRIBUTION; ANTICONVULSANT ACTIVITY; ANTICONVULSANT THERAPY; AREA UNDER THE CURVE; ARTICLE; BODY WEIGHT; CREATININE CLEARANCE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG EFFICACY; DRUG EXPOSURE; DRUG RESPONSE; ETHNICITY; HUMAN; MULTICENTER STUDY (TOPIC); PARTIAL ONSET SEIZURE; PHASE 3 CLINICAL TRIAL (TOPIC); POPULATION RESEARCH; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SEIZURE; SEX DIFFERENCE; STEADY STATE; SYSTEMIC THERAPY;

ADULT; ANTICONVULSANTS; CLINICAL TRIALS, PHASE III AS TOPIC; DIBENZAZEPINES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; HUMANS; SEIZURES;

EID: 83455178806     PISSN: 11727047     EISSN: 11791934     Source Type: Journal    
DOI: 10.2165/11596290-000000000-00000     Document Type: Article

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