Application of multianalyte microphysiometry to characterize macrophage metabolic responses to oxidized LDL and effects of an apoA-1 mimetic

Biochemical and Biophysical Research Communications

Volumn 431, Issue 2, 2013, Pages 181-185

  Kimmel, Danielle W ^a   Dole, William P ^b   Cliffel, David E ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Apolipoprotein A I mimetics; Macrophage; Microphysiometry; Oxidative burst; Oxidized LDL; Respiratory burst

Indexed keywords

1,2 DIMYRISTOYL SN GLYCERO 3 PHOSPHOCHOLINE; APOLIPOPROTEIN A1; GLUCOSE; LACTIC ACID; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHORYLCHOLINE; UNCLASSIFIED DRUG;

ACIDIFICATION; ANALYTIC METHOD; ARTICLE; ATHEROSCLEROSIS; CELL METABOLISM; GLUCOSE INTAKE; MACROPHAGE; METABOLIC RATE; MULTIANALYTE MICROPHYSIOMETRY; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN INTERACTION; RESPIRATORY BURST;

ANIMALS; APOLIPOPROTEIN A-I; ATHEROSCLEROSIS; BIOMIMETIC MATERIALS; CELL LINE; GLUCOSE; LACTIC ACID; LIPOPROTEINS, LDL; MACROPHAGES; MICE; OXYGEN; PEPTIDES; POTENTIOMETRY;

EID: 84873431350     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.12.140     Document Type: Article

References (36)

1. Ross R. Atherosclerosis - an inflammatory disease. N. Engl. J. Med. 1999, 340:115-126.
2. Hansson G.K., Robertson A.K.L., Söderberg-Nauclér C. Inflammation and atherosclerosis. Annu. Rev. Pathol. Mech. Dis. 2006, 1:297-329.
3. Endemann G., Stanton L.W., Madden K.S., Bryant C.M., White R.T., Protter A.A. CD36 is a receptor for oxidized low density lipoprotein. J. Biol. Chem. 1993, 268:11811-11816.
4. Acton S.L., Scherer P.E., Lodish H.F., Krieger M. Expression cloning of SIR-BI, a CD36-related class B scavenger receptor. J. Biol. Chem. 1994, 269:21003-21009.
5. Ramprasad M.P., Terpstra V., Kondratenko N., Quehenberger O., Steinberg D. Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein. Proc. Natl. Acad. Sci. 1996, 93:14833-14838.
6. Sawamura T., Kume N., Aoyama T., Moriwaki H., Hoshikawa H., Alba Y., Tanaka T., Miwa S., Katsura Y., Kita T., Masaki T. An endothelial receptor for oxidized low-density lipoprotein. Nature 1997, 286:73-77.
7. Chen M., Masaki T., Sawamura T. LOX-1, the receptor for oxidized low-density lipoprotein identified from endothelial cells: implications in endothelial dysfunction and atherosclerosis. Pharmacol. Ther. 2002, 95:89-100.
8. Van Lenten B.J., Wagner A.C., Jung C.L., Ruchala P., Waring A.J., Lehrer R.I., Watson A.D., Hama S., Navab M., Anantharamaiah G.M., Fogelman A.M. Anti-inflammatory apoA-I mimetic peptides bind oxidized lipids with much higher affinity than human apoA-I. J. Lipid Res. 2009, 12:2302-2311.
9. Snider R.M., McKenzie J.R., Kraft L., Kozlov E., Wikswo J.P., Cliffel D.E. The effects of cholera toxin on cellular energy metabolism. Toxins 2010, 2:632-648.
10. Eklund S.E., Thompson R.G., Snider R.M., Carney C.K., Wright D.W., Wikswo J., Cliffel D.E. Metabolic discrimination of select list agents by monitoring cellular responses in a multianalyte microphysiometer. Sensors 2009, 9:2117-2133.
11. Eklund S.E., Snider R.M., Wikswo J., Baudenbacher F., Prokop A., Cliffel D.E. Multianalyte microphysiometry as a tool in metabolomics and systems biology. J. Electroanal. Chem. 2006, 587:333-339.
12. Zeiger S.L., McKenzie J.R., Stankowski J.N., Martin J.A., Cliffel D.E., McLaughlin B. Neuron specific metabolic adaptations following multi-day exposures to oxygen glucose deprivation. BBA- Mol. Basis. Dis. 2010, 1802:1095-1104.
13. Snider R.M., Ciobanu M., Rue A.E., Cliffel D.E. A multiwalled carbon nanotube/dihydropyran composite film electrode for insulin detection in a microphysiometer chamber. Anal. Chim. Acta 2008, 609:44-52.
14. Eklund S.E., Taylor D., Kozlov E., Prokop A., Cliffel D.E. A microphysiometer for simultaneous measurement of changes in extracellular glucose, lactate, oxygen, and acidification rate. Anal. Chem. 2004, 76:519-527.
15. Via D.P., Plant A.L., Craig I.F., Gotto A.M., Smith L.C. Metabolism of normal and modified low-density lipoproteins by macrophage cell lines of murine and human origin. Biochim. Biophys. Acta 1985, 833:417-428.
16. Ota Y., Kugiyama K., Sugiyama S., Matsumura T., Terano T., Yasue H. Complexes of apoA-1 with phosphatidylcholine suppress dysregulation of arterial tone by oxidized LDL. Am. J. Physiol. 1997, 273:H1215-H1222.
17. Molecular Devices Corporation, Cytosensor microphysiometer system: user's manual. Molecular Devices: Sunnyvale, CA, 1995.
18. Hafeman D.C., Parce J.W., McConnel H.M. Light-addressable potentiometric sensor for biochemical systems. Science 1988, 240:1182-1185.
19. Owicki J.C., Bousse L.J., Hafeman D.G., Kirk G.L., Olson J.D., Wada H.G., Parce J.W. The light-addressable potentiometric sensor: principles and biological applications. Annu. Rev. Biophys. Biomol. Struct. 1994, 23.
20. Owicki J.C., Parce J.W., Kercso K.M., Sigal G.B., Muir V.C., Venter J.C., Fraser C.M., McConnell H.M. Continuous monitoring of receptor-mediated changes in the metabolic rates of living cells. Proc. Natl. Acad. Sci. 1990, 87:4007-4011.
21. De Vries H.E., Ronken E., Reinders J.H., Buchner B., Van Berkel T.J., Kuiper J. Acute effects of oxidized low density lipoprotein on metabolic responses in macrophages. FASEB J. 1998, 12:111-118.
22. Casciari J.J., Sotirchos S.V., Sutherland R.M. Variations in tumor cell growth rates and metabolism with oxygen concentration, glucose concentration, and extracellular pH. J. Cell. Physiol. 1992, 151:386-394.
23. Velkovsky M., Snider R.M., Cliffel D.E., Wikswo J.P. Modeling the measurements of cellular fluxes in microbioreactor devices using thin enzyme electrodes. J. Math. Chem. 2011, 49:251-275.
24. Van Lenten B.J., Wagner A.C., Anantharamaiah G.M., Navab M., Reddy S.T., Buga G.M., Fogelman A.M. Apolipoprotein A-I mimetic peptides. Curr. Atheroscl. Rep. 2009, 11:52-57.
25. Parhami F., Fang Z.T., Yang B., Fogelman A.M., Berliner J.A. Stimulation of Gs and inhibition of Gi protein functions by minimally oxidized LDL. Arterioscl. Throm. Vas. Biol. 1996, 15:2019-2024.
26. Yuan Y., Schoenwaelder S.M., Salem H.H., Jackson S.P. The bioactive phospholipid, lysophosphatidylcholine, induces cellular effects via G-protein-dependent activation of adenylyl cyclase. J. Biol. Chem. 1996, 271.
27. Quinn M.T., Parthasarathy S., Steinberg D. Lysophosphatidylcholine: a chemotactic factor for human monocytes and its potential role in atherogenesis. Proc. Natl. Acad. Sci. 1987, 85:2805-2809.
28. Miyazaki A., Sakai M., Suginohara Y., Hakamata H., Sakamoto Y.I., Morikawa W., Horiuchi S. Acetylated low density lipoprotein reduce ists ligand activity for the scavenger receptor after interaction with reconstituted high density lipoprotein. J. Biol. Chem. 1993, 269:5264-5269.
29. Esterbauer H., Dieber-Rotheneder M., Waeg G., Strigel G., Jürgens G. Biochemical, structural, and functional properties of oxidized low-density lipoprotein. Chem. Res. Toxicol. 1990, 3:77-92.
30. Watson C.E., Weissbach N., Kjems L., Ayalasomayajula S., Zhang Y., Chang I., Navab M., Hama S., Hough G., Reddy S.T., Soffer D., Rader D.J., Fogelman A.M., Schecter A. Treatment of patients with cardiovascular disease with L-4F, an apo-A1 mimetic, did not improve select biomarkers of HDL function. J. Lipid Res. 2011, 52:361-373.
31. Navab M., Anantharamaiah G.M., Hama S., Garber D.W., Chaddha M., Hough G., Lallone R., Fogelman A.M. Oral administration of an apo A-I mimetic peptide synthesized from D-amino acids dramatically reduces atherosclerosis in mice independent of plasma cholesterol. Circulation 2002, 105:290-292.
32. Navab M., Anantharamaiah G.M., Hama S., Hough G., Reddy S.T., Frank J.S., Garber D.W., Handattu S., Fogelman A.M. D-4F and statins synergize to render HDL antiinflammatory in mice and monkeys and cause lesion regression in old apolipoprotein E-null mice. Arterioscl. Throm. Vasc. Biol. 2005, 25:1426-1432.
33. Van Lenten B.W. AC; Navab, M; Anantharamaiah, GM; Hama, S; Reddy, ST; Fogelman, AM, Lipoprotein inflammatory properties and serum amyloid A levels but not cholesterol levels predict lesion area in cholesterol-fed rabbits. J. Lipid Res. 2007, 48:2344-2353.
34. Tawakol A., et al. J. Am. Coll. Cardiol. 2006, 48:1818-1824.
35. Ogawa M., Magata Y., Kato T., Hatano K., Ishino S., Mukai T., Shiomi M., Ito K., Saji H. Application of 18F-FDG PET for monitoring the therapeutic effect of antiinflammatory drugs on stabilization of vulnerable atherosclerotic plaques. J. Nucl. Med. 2006, 47:1845-1850.
36. Tahara N., Kai H., Ishibashi M., Nakaura H., Kaida H., Baba K., Hayabuchi N., Imaizumi T. Simvastatin attenuates plaque inflammation. J. Am. Coll. Cardiol. 2006, 48:1825-1831.