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Volumn 57, Issue 1, 2013, Pages 32-42

Atorvastatin-induced increase in progenitor cell levels is rather caused by enhanced receptor activator of NF-kappaB ligand (RANKL) cell proliferation than by bone marrow mobilization

Author keywords

Endothelium; Fibroblast growth factor 2; Progenitor cells; RANKL; Statins

Indexed keywords

ATAXIN 1; ATORVASTATIN; FIBROBLAST GROWTH FACTOR 2; GRANULOCYTE COLONY STIMULATING FACTOR; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; RECOMBINANT OSTEOCLAST DIFFERENTIATION FACTOR; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2;

EID: 84873422737     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2012.12.018     Document Type: Article
Times cited : (13)

References (49)
  • 1
    • 2942733214 scopus 로고    scopus 로고
    • Role of endothelial dysfunction in atherosclerosis
    • Davignon J., Ganz P. Role of endothelial dysfunction in atherosclerosis. Circulation 2004, 109:III27-III32.
    • (2004) Circulation , vol.109 , pp. 327-332
    • Davignon, J.1    Ganz, P.2
  • 2
    • 33646673174 scopus 로고    scopus 로고
    • Vascular wall resident progenitor cells: a source for postnatal vasculogenesis
    • Zengin E., Chalajour F., Gehling U.M., Ito W.D., Treede H., Lauke H., et al. Vascular wall resident progenitor cells: a source for postnatal vasculogenesis. Development 2006, 133:1543-1551.
    • (2006) Development , vol.133 , pp. 1543-1551
    • Zengin, E.1    Chalajour, F.2    Gehling, U.M.3    Ito, W.D.4    Treede, H.5    Lauke, H.6
  • 3
    • 0036790415 scopus 로고    scopus 로고
    • Bone marrow-derived progenitor cells modulate vascular reendothelialization and neointimal formation: effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition
    • Werner N., Priller J., Laufs U., Endres M., Bohm M., Dirnagl U., et al. Bone marrow-derived progenitor cells modulate vascular reendothelialization and neointimal formation: effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition. Arterioscler Thromb Vasc Biol 2002, 22:1567-1572.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1567-1572
    • Werner, N.1    Priller, J.2    Laufs, U.3    Endres, M.4    Bohm, M.5    Dirnagl, U.6
  • 4
    • 24344442873 scopus 로고    scopus 로고
    • Circulating endothelial progenitor cells and cardiovascular outcomes
    • Werner N., Kosiol S., Schiegl T., Ahlers P., Walenta K., Link A., et al. Circulating endothelial progenitor cells and cardiovascular outcomes. N Engl J Med 2005, 353:999-1007.
    • (2005) N Engl J Med , vol.353 , pp. 999-1007
    • Werner, N.1    Kosiol, S.2    Schiegl, T.3    Ahlers, P.4    Walenta, K.5    Link, A.6
  • 5
    • 0037173080 scopus 로고    scopus 로고
    • Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells
    • Walter D.H., Rittig K., Bahlmann F.H., Kirchmair R., Silver M., Murayama T., et al. Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells. Circulation 2002, 105:3017-3024.
    • (2002) Circulation , vol.105 , pp. 3017-3024
    • Walter, D.H.1    Rittig, K.2    Bahlmann, F.H.3    Kirchmair, R.4    Silver, M.5    Murayama, T.6
  • 6
    • 0038000632 scopus 로고    scopus 로고
    • Estrogen increases bone marrow-derived endothelial progenitor cell production and diminishes neointima formation
    • Strehlow K., Werner N., Berweiler J., Link A., Dirnagl U., Priller J., et al. Estrogen increases bone marrow-derived endothelial progenitor cell production and diminishes neointima formation. Circulation 2003, 107:3059-3065.
    • (2003) Circulation , vol.107 , pp. 3059-3065
    • Strehlow, K.1    Werner, N.2    Berweiler, J.3    Link, A.4    Dirnagl, U.5    Priller, J.6
  • 7
    • 0345167094 scopus 로고    scopus 로고
    • Mobilized endothelial progenitor cells by granulocyte-macrophage colony-stimulating factor accelerate reendothelialization and reduce vascular inflammation after intravascular radiation
    • Cho H.J., Kim H.S., Lee M.M., Kim D.H., Yang H.J., Hur J., et al. Mobilized endothelial progenitor cells by granulocyte-macrophage colony-stimulating factor accelerate reendothelialization and reduce vascular inflammation after intravascular radiation. Circulation 2003, 108:2918-2925.
    • (2003) Circulation , vol.108 , pp. 2918-2925
    • Cho, H.J.1    Kim, H.S.2    Lee, M.M.3    Kim, D.H.4    Yang, H.J.5    Hur, J.6
  • 8
    • 33744983304 scopus 로고    scopus 로고
    • Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells
    • Kollet O., Dar A., Shivtiel S., Kalinkovich A., Lapid K., Sztainberg Y., et al. Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells. Nat Med 2006, 12:657-664.
    • (2006) Nat Med , vol.12 , pp. 657-664
    • Kollet, O.1    Dar, A.2    Shivtiel, S.3    Kalinkovich, A.4    Lapid, K.5    Sztainberg, Y.6
  • 9
    • 54449089664 scopus 로고    scopus 로고
    • The Wnt antagonist Dickkopf-1 mobilizes vasculogenic progenitor cells via activation of the bone marrow endosteal stem cell niche
    • Aicher A., Kollet O., Heeschen C., Liebner S., Urbich C., Ihling C., et al. The Wnt antagonist Dickkopf-1 mobilizes vasculogenic progenitor cells via activation of the bone marrow endosteal stem cell niche. Circ Res 2008, 103:796-803.
    • (2008) Circ Res , vol.103 , pp. 796-803
    • Aicher, A.1    Kollet, O.2    Heeschen, C.3    Liebner, S.4    Urbich, C.5    Ihling, C.6
  • 10
    • 18444389451 scopus 로고    scopus 로고
    • Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand
    • Heissig B., Hattori K., Dias S., Friedrich M., Ferris B., Hackett N.R., et al. Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell 2002, 109:625-637.
    • (2002) Cell , vol.109 , pp. 625-637
    • Heissig, B.1    Hattori, K.2    Dias, S.3    Friedrich, M.4    Ferris, B.5    Hackett, N.R.6
  • 11
    • 0035912855 scopus 로고    scopus 로고
    • Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease
    • Vasa M., Fichtlscherer S., Adler K., Aicher A., Martin H., Zeiher A.M., et al. Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease. Circulation 2001, 103:2885-2890.
    • (2001) Circulation , vol.103 , pp. 2885-2890
    • Vasa, M.1    Fichtlscherer, S.2    Adler, K.3    Aicher, A.4    Martin, H.5    Zeiher, A.M.6
  • 12
    • 0034898468 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitor mobilizes bone marrow-derived endothelial progenitor cells
    • Llevadot J., Murasawa S., Kureishi Y., Uchida S., Masuda H., Kawamoto A., et al. HMG-CoA reductase inhibitor mobilizes bone marrow-derived endothelial progenitor cells. J Clin Invest 2001, 108:399-405.
    • (2001) J Clin Invest , vol.108 , pp. 399-405
    • Llevadot, J.1    Murasawa, S.2    Kureishi, Y.3    Uchida, S.4    Masuda, H.5    Kawamoto, A.6
  • 13
    • 19944429519 scopus 로고    scopus 로고
    • Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease
    • Nissen S.E., Tuzcu E.M., Schoenhagen P., Crowe T., Sasiela W.J., Tsai J., et al. Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease. N Engl J Med 2005, 352:29-38.
    • (2005) N Engl J Med , vol.352 , pp. 29-38
    • Nissen, S.E.1    Tuzcu, E.M.2    Schoenhagen, P.3    Crowe, T.4    Sasiela, W.J.5    Tsai, J.6
  • 14
    • 0038756432 scopus 로고    scopus 로고
    • Impaired osteoclast formation in bone marrow cultures of Fgf2 null mice in response to parathyroid hormone
    • Okada Y., Montero A., Zhang X., Sobue T., Lorenzo J., Doetschman T., et al. Impaired osteoclast formation in bone marrow cultures of Fgf2 null mice in response to parathyroid hormone. J Biol Chem 2003, 278:21258-21266.
    • (2003) J Biol Chem , vol.278 , pp. 21258-21266
    • Okada, Y.1    Montero, A.2    Zhang, X.3    Sobue, T.4    Lorenzo, J.5    Doetschman, T.6
  • 15
    • 62649086172 scopus 로고    scopus 로고
    • The pleiotropic effects of statins on endothelial function, vascular inflammation, immunomodulation and thrombogenesis
    • Blum A., Shamburek R. The pleiotropic effects of statins on endothelial function, vascular inflammation, immunomodulation and thrombogenesis. Atherosclerosis 2009, 203:325-330.
    • (2009) Atherosclerosis , vol.203 , pp. 325-330
    • Blum, A.1    Shamburek, R.2
  • 16
    • 0036242398 scopus 로고    scopus 로고
    • Statins as modulators of bone formation
    • Edwards C.J., Spector T.D. Statins as modulators of bone formation. Arthritis Res 2002, 4:151-153.
    • (2002) Arthritis Res , vol.4 , pp. 151-153
    • Edwards, C.J.1    Spector, T.D.2
  • 17
    • 77955152492 scopus 로고    scopus 로고
    • Synergistic effects of telmisartan and simvastatin on endothelial progenitor cells
    • Steinmetz M., Brouwers C., Nickenig G., Wassmann S. Synergistic effects of telmisartan and simvastatin on endothelial progenitor cells. J Cell Mol Med 2008, 14:1645-1656.
    • (2008) J Cell Mol Med , vol.14 , pp. 1645-1656
    • Steinmetz, M.1    Brouwers, C.2    Nickenig, G.3    Wassmann, S.4
  • 19
  • 20
    • 0031017180 scopus 로고    scopus 로고
    • Vascular wound healing and neointima formation induced by perivascular electric injury in mice
    • Carmeliet P., Moons L., Stassen J.M., De Mol M., Bouche A., van den Oord J.J., et al. Vascular wound healing and neointima formation induced by perivascular electric injury in mice. Am J Pathol 1997, 150:761-776.
    • (1997) Am J Pathol , vol.150 , pp. 761-776
    • Carmeliet, P.1    Moons, L.2    Stassen, J.M.3    De Mol, M.4    Bouche, A.5    van den Oord, J.J.6
  • 21
    • 66949135110 scopus 로고    scopus 로고
    • High-density lipoprotein exerts vasculoprotection via endothelial progenitor cells
    • Petoumenos V., Nickenig G., Werner N. High-density lipoprotein exerts vasculoprotection via endothelial progenitor cells. J Cell Mol Med 2009, 13:4623-4635.
    • (2009) J Cell Mol Med , vol.13 , pp. 4623-4635
    • Petoumenos, V.1    Nickenig, G.2    Werner, N.3
  • 22
    • 57549087201 scopus 로고    scopus 로고
    • Bone morphogenetic proteins 2 and 4 are selectively expressed by late outgrowth endothelial progenitor cells and promote neoangiogenesis
    • Smadja D.M., Bieche I., Silvestre J.S., Germain S., Cornet A., Laurendeau I., et al. Bone morphogenetic proteins 2 and 4 are selectively expressed by late outgrowth endothelial progenitor cells and promote neoangiogenesis. Arterioscler Thromb Vasc Biol 2008, 28:2137-2143.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 2137-2143
    • Smadja, D.M.1    Bieche, I.2    Silvestre, J.S.3    Germain, S.4    Cornet, A.5    Laurendeau, I.6
  • 23
    • 1542313876 scopus 로고    scopus 로고
    • Interleukin-6 induces oxidative stress and endothelial dysfunction by overexpression of the angiotensin II type 1 receptor
    • Wassmann S., Stumpf M., Strehlow K., Schmid A., Schieffer B., Bohm M., et al. Interleukin-6 induces oxidative stress and endothelial dysfunction by overexpression of the angiotensin II type 1 receptor. Circ Res 2004, 94:534-541.
    • (2004) Circ Res , vol.94 , pp. 534-541
    • Wassmann, S.1    Stumpf, M.2    Strehlow, K.3    Schmid, A.4    Schieffer, B.5    Bohm, M.6
  • 24
    • 69449101599 scopus 로고    scopus 로고
    • FGF-2 stimulation of RANK ligand expression in Paget's disease of bone
    • Sundaram K., Senn J., Yuvaraj S., Rao D.S., Reddy S.V. FGF-2 stimulation of RANK ligand expression in Paget's disease of bone. Mol Endocrinol 2009, 23:1445-1454.
    • (2009) Mol Endocrinol , vol.23 , pp. 1445-1454
    • Sundaram, K.1    Senn, J.2    Yuvaraj, S.3    Rao, D.S.4    Reddy, S.V.5
  • 25
    • 1642410788 scopus 로고    scopus 로고
    • Functional role for heat shock factors in the transcriptional regulation of human RANK ligand gene expression in stromal/osteoblast cells
    • Roccisana J.L., Kawanabe N., Kajiya H., Koide M., Roodman G.D., Reddy S.V. Functional role for heat shock factors in the transcriptional regulation of human RANK ligand gene expression in stromal/osteoblast cells. J Biol Chem 2004, 279:10500-10507.
    • (2004) J Biol Chem , vol.279 , pp. 10500-10507
    • Roccisana, J.L.1    Kawanabe, N.2    Kajiya, H.3    Koide, M.4    Roodman, G.D.5    Reddy, S.V.6
  • 26
    • 0033547351 scopus 로고    scopus 로고
    • Basic fibroblast growth factor induces osteoclast formation by reciprocally regulating the production of osteoclast differentiation factor and osteoclastogenesis inhibitory factor in mouse osteoblastic cells
    • Nakagawa N., Yasuda H., Yano K., Mochizuki S., Kobayashi N., Fujimoto H., et al. Basic fibroblast growth factor induces osteoclast formation by reciprocally regulating the production of osteoclast differentiation factor and osteoclastogenesis inhibitory factor in mouse osteoblastic cells. Biochem Biophys Res Commun 1999, 265:158-163.
    • (1999) Biochem Biophys Res Commun , vol.265 , pp. 158-163
    • Nakagawa, N.1    Yasuda, H.2    Yano, K.3    Mochizuki, S.4    Kobayashi, N.5    Fujimoto, H.6
  • 27
    • 77950546974 scopus 로고    scopus 로고
    • Troubleshooting: Quantification of mobilization of progenitor cell subsets from bone marrow in vivo
    • Pitchford S.C., Hahnel M.J., Jones C.P., Rankin S.M. Troubleshooting: Quantification of mobilization of progenitor cell subsets from bone marrow in vivo. J Pharmacol Toxicol Methods 2010, 61:113-121.
    • (2010) J Pharmacol Toxicol Methods , vol.61 , pp. 113-121
    • Pitchford, S.C.1    Hahnel, M.J.2    Jones, C.P.3    Rankin, S.M.4
  • 28
    • 0034926855 scopus 로고    scopus 로고
    • Endothelial function and coronary artery disease
    • Kinlay S., Libby P., Ganz P. Endothelial function and coronary artery disease. Curr Opin Lipidol 2001, 12:383-389.
    • (2001) Curr Opin Lipidol , vol.12 , pp. 383-389
    • Kinlay, S.1    Libby, P.2    Ganz, P.3
  • 29
    • 79961031512 scopus 로고    scopus 로고
    • Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin-mediated endothelial nitric oxide synthase coupling
    • Antoniades C., Bakogiannis C., Leeson P., Guzik T.J., Zhang M.H., Tousoulis D., et al. Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin-mediated endothelial nitric oxide synthase coupling. Circulation 2011, 124:335-345.
    • (2011) Circulation , vol.124 , pp. 335-345
    • Antoniades, C.1    Bakogiannis, C.2    Leeson, P.3    Guzik, T.J.4    Zhang, M.H.5    Tousoulis, D.6
  • 30
    • 78650832968 scopus 로고    scopus 로고
    • Effects of atorvastatin and rosuvastatin on thromboxane-dependent platelet activation and oxidative stress in hypercholesterolemia
    • Puccetti L., Santilli F., Pasqui A.L., Lattanzio S., Liani R., Ciani F., et al. Effects of atorvastatin and rosuvastatin on thromboxane-dependent platelet activation and oxidative stress in hypercholesterolemia. Atherosclerosis 2011, 214:122-128.
    • (2011) Atherosclerosis , vol.214 , pp. 122-128
    • Puccetti, L.1    Santilli, F.2    Pasqui, A.L.3    Lattanzio, S.4    Liani, R.5    Ciani, F.6
  • 31
    • 77953127955 scopus 로고    scopus 로고
    • Atorvastatin reduces macrophage accumulation in atherosclerotic plaques: a comparison of a nonstatin-based regimen in patients undergoing carotid endarterectomy
    • Puato M., Faggin E., Rattazzi M., Zambon A., Cipollone F., Grego F., et al. Atorvastatin reduces macrophage accumulation in atherosclerotic plaques: a comparison of a nonstatin-based regimen in patients undergoing carotid endarterectomy. Stroke 2010, 41:1163-1168.
    • (2010) Stroke , vol.41 , pp. 1163-1168
    • Puato, M.1    Faggin, E.2    Rattazzi, M.3    Zambon, A.4    Cipollone, F.5    Grego, F.6
  • 32
    • 79955812158 scopus 로고    scopus 로고
    • Effects of immunomodulatory drugs on plasma inflammatory markers in a rabbit model of atherosclerosis
    • Houssen M.E., Haron M.M., Metwally S.S., Ibrahim T.M. Effects of immunomodulatory drugs on plasma inflammatory markers in a rabbit model of atherosclerosis. J Physiol Biochem 2011, 67:115-120.
    • (2011) J Physiol Biochem , vol.67 , pp. 115-120
    • Houssen, M.E.1    Haron, M.M.2    Metwally, S.S.3    Ibrahim, T.M.4
  • 33
    • 8544236989 scopus 로고    scopus 로고
    • Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells
    • Spyridopoulos I., Haendeler J., Urbich C., Brummendorf T.H., Oh H., Schneider M.D., et al. Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells. Circulation 2004, 110:3136-3142.
    • (2004) Circulation , vol.110 , pp. 3136-3142
    • Spyridopoulos, I.1    Haendeler, J.2    Urbich, C.3    Brummendorf, T.H.4    Oh, H.5    Schneider, M.D.6
  • 34
    • 77949392111 scopus 로고    scopus 로고
    • - progenitor cells and indices of angiogenesis (vascular endothelial growth factor and the angiopoietins 1 and 2) in atherosclerotic vascular disease and diabetes mellitus
    • - progenitor cells and indices of angiogenesis (vascular endothelial growth factor and the angiopoietins 1 and 2) in atherosclerotic vascular disease and diabetes mellitus. J Intern Med 2010, 267:385-393.
    • (2010) J Intern Med , vol.267 , pp. 385-393
    • Jaumdally, R.J.1    Goon, P.K.2    Varma, C.3    Blann, A.D.4    Lip, G.Y.5
  • 35
    • 0034778449 scopus 로고    scopus 로고
    • Regulation of osteoclast differentiation by fibroblast growth factor 2: stimulation of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor expression in osteoblasts and inhibition of macrophage colony-stimulating factor function in osteoclast precursors
    • Chikazu D., Katagiri M., Ogasawara T., Ogata N., Shimoaka T., Takato T., et al. Regulation of osteoclast differentiation by fibroblast growth factor 2: stimulation of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor expression in osteoblasts and inhibition of macrophage colony-stimulating factor function in osteoclast precursors. J Bone Miner Res 2001, 16:2074-2081.
    • (2001) J Bone Miner Res , vol.16 , pp. 2074-2081
    • Chikazu, D.1    Katagiri, M.2    Ogasawara, T.3    Ogata, N.4    Shimoaka, T.5    Takato, T.6
  • 36
    • 42749083246 scopus 로고    scopus 로고
    • Functions of RANKL/RANK/OPG in bone modeling and remodeling
    • Boyce B.F., Xing L. Functions of RANKL/RANK/OPG in bone modeling and remodeling. Arch Biochem Biophys 2008, 473:139-146.
    • (2008) Arch Biochem Biophys , vol.473 , pp. 139-146
    • Boyce, B.F.1    Xing, L.2
  • 37
    • 79957463868 scopus 로고    scopus 로고
    • Runx2-upregulated receptor activator of nuclear factor kappaB ligand in calcifying smooth muscle cells promotes migration and osteoclastic differentiation of macrophages
    • Byon C.H., Sun Y., Chen J., Yuan K., Mao X., Heath J.M., et al. Runx2-upregulated receptor activator of nuclear factor kappaB ligand in calcifying smooth muscle cells promotes migration and osteoclastic differentiation of macrophages. Arterioscler Thromb Vasc Biol 2011, 31:1387-1396.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 1387-1396
    • Byon, C.H.1    Sun, Y.2    Chen, J.3    Yuan, K.4    Mao, X.5    Heath, J.M.6
  • 38
    • 50549102361 scopus 로고    scopus 로고
    • Differential profile of the OPG/RANKL/RANK-system in degenerative aortic native and bioprosthetic valves
    • Steinmetz M., Skowasch D., Wernert N., Welsch U., Preusse C.J., Welz A., et al. Differential profile of the OPG/RANKL/RANK-system in degenerative aortic native and bioprosthetic valves. J Heart Valve Dis 2008, 17:187-193.
    • (2008) J Heart Valve Dis , vol.17 , pp. 187-193
    • Steinmetz, M.1    Skowasch, D.2    Wernert, N.3    Welsch, U.4    Preusse, C.J.5    Welz, A.6
  • 39
    • 70349568748 scopus 로고    scopus 로고
    • Osteoprotegerin promotes fibrous cap formation in atherosclerotic lesions of ApoE-deficient mice-brief report
    • Ovchinnikova O., Gylfe A., Bailey L., Nordstrom A., Rudling M., Jung C., et al. Osteoprotegerin promotes fibrous cap formation in atherosclerotic lesions of ApoE-deficient mice-brief report. Arterioscler Thromb Vasc Biol 2009, 29:1478-1480.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1478-1480
    • Ovchinnikova, O.1    Gylfe, A.2    Bailey, L.3    Nordstrom, A.4    Rudling, M.5    Jung, C.6
  • 40
    • 0033611467 scopus 로고    scopus 로고
    • OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
    • Kong Y.Y., Yoshida H., Sarosi I., Tan H.L., Timms E., Capparelli C., et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 1999, 397:315-323.
    • (1999) Nature , vol.397 , pp. 315-323
    • Kong, Y.Y.1    Yoshida, H.2    Sarosi, I.3    Tan, H.L.4    Timms, E.5    Capparelli, C.6
  • 41
    • 41949089365 scopus 로고    scopus 로고
    • Rapid endothelial turnover in atherosclerosis-prone areas coincides with stem cell repair in apolipoprotein E-deficient mice
    • Foteinos G., Hu Y., Xiao Q., Metzler B., Xu Q. Rapid endothelial turnover in atherosclerosis-prone areas coincides with stem cell repair in apolipoprotein E-deficient mice. Circulation 2008, 117:1856-1863.
    • (2008) Circulation , vol.117 , pp. 1856-1863
    • Foteinos, G.1    Hu, Y.2    Xiao, Q.3    Metzler, B.4    Xu, Q.5
  • 42
    • 79958149425 scopus 로고    scopus 로고
    • Activation of endothelial toll-like receptor 3 impairs endothelial function
    • Zimmer S., Steinmetz M., Asdonk T., Motz I., Coch C., Hartmann E., et al. Activation of endothelial toll-like receptor 3 impairs endothelial function. Circ Res 2011, 108:1358-1366.
    • (2011) Circ Res , vol.108 , pp. 1358-1366
    • Zimmer, S.1    Steinmetz, M.2    Asdonk, T.3    Motz, I.4    Coch, C.5    Hartmann, E.6
  • 43
    • 0038814315 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes
    • Assmus B., Urbich C., Aicher A., Hofmann W.K., Haendeler J., Rossig L., et al. HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes. Circ Res 2003, 92:1049-1055.
    • (2003) Circ Res , vol.92 , pp. 1049-1055
    • Assmus, B.1    Urbich, C.2    Aicher, A.3    Hofmann, W.K.4    Haendeler, J.5    Rossig, L.6
  • 44
    • 78649825728 scopus 로고    scopus 로고
    • Coronary endothelial dysfunction in humans is associated with coronary retention of osteogenic endothelial progenitor cells
    • Gossl M., Modder U.I., Gulati R., Rihal C.S., Prasad A., Loeffler D., et al. Coronary endothelial dysfunction in humans is associated with coronary retention of osteogenic endothelial progenitor cells. Eur Heart J 2010, 31:2909-2914.
    • (2010) Eur Heart J , vol.31 , pp. 2909-2914
    • Gossl, M.1    Modder, U.I.2    Gulati, R.3    Rihal, C.S.4    Prasad, A.5    Loeffler, D.6
  • 45
    • 61449157230 scopus 로고    scopus 로고
    • Osteoprotegerin and RANKL differentially regulate angiogenesis and endothelial cell function
    • McGonigle J.S., Giachelli C.M., Scatena M. Osteoprotegerin and RANKL differentially regulate angiogenesis and endothelial cell function. Angiogenesis 2009, 12:35-46.
    • (2009) Angiogenesis , vol.12 , pp. 35-46
    • McGonigle, J.S.1    Giachelli, C.M.2    Scatena, M.3
  • 46
    • 33846925850 scopus 로고    scopus 로고
    • Receptor activator of nuclear factor (NF)-kappaB ligand (RANKL) increases vascular permeability: impaired permeability and angiogenesis in eNOS-deficient mice
    • Min J.K., Cho Y.L., Choi J.H., Kim Y., Kim J.H., Yu Y.S., et al. Receptor activator of nuclear factor (NF)-kappaB ligand (RANKL) increases vascular permeability: impaired permeability and angiogenesis in eNOS-deficient mice. Blood 2007, 109:1495-1502.
    • (2007) Blood , vol.109 , pp. 1495-1502
    • Min, J.K.1    Cho, Y.L.2    Choi, J.H.3    Kim, Y.4    Kim, J.H.5    Yu, Y.S.6
  • 47
    • 82555183512 scopus 로고    scopus 로고
    • Simvastatin inhibits osteoclast differentiation by scavenging reactive oxygen species
    • Moon H.J., Kim S.E., Yun Y.P., Hwang Y.S., Bang J.B., Park J.H., et al. Simvastatin inhibits osteoclast differentiation by scavenging reactive oxygen species. Exp Mol Med 2011, 43:605-612.
    • (2011) Exp Mol Med , vol.43 , pp. 605-612
    • Moon, H.J.1    Kim, S.E.2    Yun, Y.P.3    Hwang, Y.S.4    Bang, J.B.5    Park, J.H.6
  • 48
    • 27744519739 scopus 로고    scopus 로고
    • Statins modulate the levels of osteoprotegerin/receptor activator of NFkappaB ligand mRNA in mouse bone-cell cultures
    • Kaji H., Kanatani M., Sugimoto T., Chihara K. Statins modulate the levels of osteoprotegerin/receptor activator of NFkappaB ligand mRNA in mouse bone-cell cultures. Horm Metab Res 2005, 37:589-592.
    • (2005) Horm Metab Res , vol.37 , pp. 589-592
    • Kaji, H.1    Kanatani, M.2    Sugimoto, T.3    Chihara, K.4
  • 49


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