Sodium arsenite exposure inhibits AKT and Stat3 activation, suppresses self-renewal and induces apoptotic death of embryonic stem cells

Apoptosis

Volumn 18, Issue 2, 2013, Pages 188-200

  Ivanov, Vladimir N ^a   Wen, Gengyun ^a   Hei, Tom K ^a  

^a Columbia University ^*  (United States)

Author keywords

AKT; Apoptosis; Embryonic stem cells; Sodium arsenite

Indexed keywords

ARSENITE SODIUM; CASPASE 3 INHIBITOR; CASPASE 9 INHIBITOR; INTERLEUKIN 6; INTERLEUKIN 6 ANTIBODY; OCTAMER TRANSCRIPTION FACTOR 4; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAT3 PROTEIN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL RENEWAL; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; EMBRYO; EMBRYONIC STEM CELL; ENZYME ACTIVATION; EXPOSURE; G2 PHASE CELL CYCLE CHECKPOINT; INHIBITION KINETICS; M PHASE CELL CYCLE CHECKPOINT; MOUSE; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; ARSENITES; CELL SURVIVAL; EMBRYONIC STEM CELLS; MICE; NEURAL STEM CELLS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SODIUM COMPOUNDS; STAT3 TRANSCRIPTION FACTOR;

ANIMALIA;

EID: 84873422666     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-012-0779-1     Document Type: Article

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