-
1
-
-
0141885079
-
Transcriptional regulation of the heme oxygenase-1 gene via the stress response element pathway
-
DOI 10.2174/1381612033453730
-
J Alam JL Cook 2003 Transcriptional regulation of the heme oxygenase-1 gene via the stress response element pathway Curr Pharm Des 9 2499 2511 14529549 10.2174/1381612033453730 1:CAS:528:DC%2BD3sXotlWjtr0%3D (Pubitemid 37236369)
-
(2003)
Current Pharmaceutical Design
, vol.9
, Issue.30
, pp. 2499-2511
-
-
Alam, J.1
Cook, J.L.2
-
2
-
-
78049442406
-
Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential
-
20643109 10.1016/j.bcp.2010.07.014 1:CAS:528:DC%2BC3cXhtlKrs77P
-
A Paine B Eiz-Vesper R Blasczyk S Immenschuh 2010 Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential Biochem Pharmacol 80 1895 1903 20643109 10.1016/j.bcp.2010.07.014 1:CAS:528:DC%2BC3cXhtlKrs77P
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 1895-1903
-
-
Paine, A.1
Eiz-Vesper, B.2
Blasczyk, R.3
Immenschuh, S.4
-
3
-
-
1642291631
-
Small Interfering RNA Targeting Heme Oxygenase-1 Enhances Ischemia-Reperfusion-induced Lung Apoptosis
-
DOI 10.1074/jbc.M312941200
-
X Zhang P Shan D Jiang PW Noble NG Abraham A Kappas PJ Lee 2004 Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis J Biol Chem 279 10677 10684 14688267 10.1074/jbc.M312941200 1:CAS:528:DC%2BD2cXhvFChsbY%3D (Pubitemid 38372680)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.11
, pp. 10677-10684
-
-
Zhang, X.1
Shan, P.2
Jiang, D.3
Noble, P.W.4
Abraham, N.G.5
Kappas, A.6
Lee, P.J.7
-
4
-
-
1542335553
-
Regulation of Heme Oxygenase-1 Expression through the Phosphatidylinositol 3-Kinase/Akt Pathway and the Nrf2 Transcription Factor in Response to the Antioxidant Phytochemical Carnosol
-
DOI 10.1074/jbc.M309660200
-
D Martin AI Rojo M Salinas R Diaz G Gallardo J Alam CM De Galarreta A Cuadrado 2004 Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol J Biol Chem 279 8919 8929 14688281 10.1074/jbc.M309660200 1:CAS:528:DC%2BD2cXhs1Onurs%3D (Pubitemid 38295953)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.10
, pp. 8919-8929
-
-
Martin, D.1
Rojo, A.I.2
Salinas, M.3
Diaz, R.4
Gallardo, G.5
Alam, J.6
Ruiz De Galarreta, C.M.7
Cuadrado, A.8
-
5
-
-
77949525185
-
Mechanisms of cell protection by heme oxygenase-1
-
20055707 10.1146/annurev.pharmtox.010909.105600 1:CAS:528: DC%2BC3cXisVelurk%3D
-
R Gozzelino V Jeney MP Soares 2010 Mechanisms of cell protection by heme oxygenase-1 Annu Rev Pharmacol Toxicol 50 323 354 20055707 10.1146/annurev. pharmtox.010909.105600 1:CAS:528:DC%2BC3cXisVelurk%3D
-
(2010)
Annu Rev Pharmacol Toxicol
, vol.50
, pp. 323-354
-
-
Gozzelino, R.1
Jeney, V.2
Soares, M.P.3
-
6
-
-
0038745911
-
Heme oxygenase-1 in growth control and its clinical application to vascular disease
-
DOI 10.1002/jcp.10274
-
W Durante 2003 Heme oxygenase-1 in growth control and its clinical application to vascular disease J Cell Physiol 195 373 382 12704646 10.1002/jcp.10274 1:CAS:528:DC%2BD3sXjs1yhs7o%3D (Pubitemid 36529865)
-
(2003)
Journal of Cellular Physiology
, vol.195
, Issue.3
, pp. 373-382
-
-
Durante, W.1
-
7
-
-
77950346282
-
Immunity, inflammation, and cancer
-
20303878 10.1016/j.cell.2010.01.025 1:CAS:528:DC%2BC3cXlsVSgu7g%3D
-
SI Grivennikov FR Greten M Karin 2010 Immunity, inflammation, and cancer Cell 140 883 899 20303878 10.1016/j.cell.2010.01.025 1:CAS:528: DC%2BC3cXlsVSgu7g%3D
-
(2010)
Cell
, vol.140
, pp. 883-899
-
-
Grivennikov, S.I.1
Greten, F.R.2
Karin, M.3
-
8
-
-
70350778443
-
An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation
-
19878981 10.1016/j.cell.2009.10.014 1:CAS:528:DC%2BD1MXhsFylsbbM
-
D Iliopoulos HA Hirsch K Struhl 2009 An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation Cell 139 693 706 19878981 10.1016/j.cell.2009.10.014 1:CAS:528:DC%2BD1MXhsFylsbbM
-
(2009)
Cell
, vol.139
, pp. 693-706
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Struhl, K.3
-
9
-
-
79251648307
-
Suppression of the proinflammatory response of metastatic melanoma cells increases TRAIL-induced apoptosis
-
21268068 10.1002/jcb.22934 1:CAS:528:DC%2BC3MXhtVehtbc%3D
-
VN Ivanov MA Partridge SX Huang TK Hei 2011 Suppression of the proinflammatory response of metastatic melanoma cells increases TRAIL-induced apoptosis J Cell Biochem 112 463 475 21268068 10.1002/jcb.22934 1:CAS:528:DC%2BC3MXhtVehtbc%3D
-
(2011)
J Cell Biochem
, vol.112
, pp. 463-475
-
-
Ivanov, V.N.1
Partridge, M.A.2
Huang, S.X.3
Hei, T.K.4
-
10
-
-
2542443312
-
Arsenite sensitizes human melanomas to apoptosis via tumor necrosis factor α-mediated pathway
-
DOI 10.1074/jbc.M314131200
-
VN Ivanov TK Hei 2004 Arsenite sensitizes human melanomas to apoptosis via tumor necrosis factor alpha-mediated pathway J Biol Chem 279 22747 22758 15028728 10.1074/jbc.M314131200 1:CAS:528:DC%2BD2cXjvF2rurc%3D (Pubitemid 38679475)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.21
, pp. 22747-22758
-
-
Ivanov, V.N.1
Hei, T.K.2
-
11
-
-
13244252267
-
Combined treatment with EGFR inhibitors and arsenite upregulated apoptosis in human EGFR-positive melanomas: A role of suppression of the PI3K-AKT pathway
-
DOI 10.1038/sj.onc.1208125
-
VN Ivanov TK Hei 2005 Combined treatment with EGFR inhibitors and arsenite upregulated apoptosis in human EGFR-positive melanomas: a role of suppression of the PI3K-AKT pathway Oncogene 24 616 626 15580309 10.1038/sj.onc.1208125 1:CAS:528:DC%2BD2MXltVShtg%3D%3D (Pubitemid 40188566)
-
(2005)
Oncogene
, vol.24
, Issue.4
, pp. 616-626
-
-
Ivanov, V.N.1
Hei, T.K.2
-
12
-
-
0032487923
-
Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide
-
DOI 10.1056/NEJM199811053391901
-
SL Soignet P Maslak Z-G Wang S Jhanwar E Calleja LJ Dardashti D Corso A DeBlasio J Gabrilove DA Scheinberg PP Pandolfi RP Warrell 1998 Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide N Engl J Med 339 1341 1348 9801394 10.1056/NEJM199811053391901 1:CAS:528:DyaK1cXnsVOgu7k%3D (Pubitemid 28509343)
-
(1998)
New England Journal of Medicine
, vol.339
, Issue.19
, pp. 1341-1348
-
-
Soignet, S.L.1
Maslak, P.2
Wang, Z.-G.3
Jhanwar, S.4
Calleja, E.5
Dardashti, L.J.6
Corso, D.7
DeBlasio, A.8
Gabrilove, J.9
Scheinberg, D.A.10
Pandolfi, P.P.11
Warrell Jr., R.P.12
-
13
-
-
0036690367
-
Arsenic trioxide inhibits growth of human multiple myeloma cells in the bone marrow microenvironment
-
12492118 1:CAS:528:DC%2BD3sXlslGrtA%3D%3D
-
T Hayashi T Hideshima M Akiyama P Richardson RL Schlossman D Chauhan NC Munshi S Waxman KC Anderson 2002 Arsenic trioxide inhibits growth of human multiple myeloma cells in the bone marrow microenvironment Mol Cancer Ther 1 851 860 12492118 1:CAS:528:DC%2BD3sXlslGrtA%3D%3D
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 851-860
-
-
Hayashi, T.1
Hideshima, T.2
Akiyama, M.3
Richardson, P.4
Schlossman, R.L.5
Chauhan, D.6
Munshi, N.C.7
Waxman, S.8
Anderson, K.C.9
-
14
-
-
67650523965
-
Induction of the cytoprotective enzyme heme oxygenase-1 by statins is enhanced in vascular endothelium exposed to laminar shear stress and impaired by disturbed flow
-
19457866 10.1074/jbc.M109.009886 1:CAS:528:DC%2BD1MXotVKnsbY%3D
-
F Ali M Zakkar K Karu EA Lidington SS Hamdulay JJ Boyle M Zloh A Bauer DO Haskard PC Evans JC Mason 2009 Induction of the cytoprotective enzyme heme oxygenase-1 by statins is enhanced in vascular endothelium exposed to laminar shear stress and impaired by disturbed flow J Biol Chem 284 18882 18892 19457866 10.1074/jbc.M109.009886 1:CAS:528:DC%2BD1MXotVKnsbY%3D
-
(2009)
J Biol Chem
, vol.284
, pp. 18882-18892
-
-
Ali, F.1
Zakkar, M.2
Karu, K.3
Lidington, E.A.4
Hamdulay, S.S.5
Boyle, J.J.6
Zloh, M.7
Bauer, A.8
Haskard, D.O.9
Evans, P.C.10
Mason, J.C.11
-
15
-
-
77956394303
-
Mitochondrial dysfunction induced by statin contributes to endothelial dysfunction in patients with coronary artery disease
-
20383667 10.1007/s12012-010-9071-1 1:CAS:528:DC%2BC3cXmtVSmtr8%3D
-
Y-L Dai T-H Luk C-W Siu K-H Yiu H-T Chan S Lee S-W Li S Tam B Fong C-P Lau H-F Tse 2010 Mitochondrial dysfunction induced by statin contributes to endothelial dysfunction in patients with coronary artery disease Cardiovasc Toxicol 10 130 138 20383667 10.1007/s12012-010-9071-1 1:CAS:528: DC%2BC3cXmtVSmtr8%3D
-
(2010)
Cardiovasc Toxicol
, vol.10
, pp. 130-138
-
-
Dai, Y.-L.1
Luk, T.-H.2
Siu, C.-W.3
Yiu, K.-H.4
Chan, H.-T.5
Lee, S.6
Li, S.-W.7
Tam, S.8
Fong, B.9
Lau, C.-P.10
Tse, H.-F.11
-
16
-
-
34347254482
-
Sodium arsenite accelerates TRAIL-mediated apoptosis in melanoma cells through upregulation of TRAIL-R1/R2 surface levels and downregulation of cFLIP expression
-
DOI 10.1016/j.yexcr.2006.09.019, PII S0014482706003909
-
VN Ivanov TK Hei 2006 Sodium arsenite accelerates TRAIL-mediated apoptosis in melanoma cells through upregulation of TRAIL-R1/R2 surface levels and downregulation of cFLIP expression Exp Cell Res 312 4120 4138 17070520 10.1016/j.yexcr.2006.09.019 1:CAS:528:DC%2BD28Xht1Krt7%2FO (Pubitemid 44828055)
-
(2006)
Experimental Cell Research
, vol.312
, Issue.20
, pp. 4120-4138
-
-
Ivanov, V.N.1
Hei, T.K.2
-
17
-
-
1842556757
-
Recent Advances in Melanoma Biology
-
DOI 10.1634/theoncologist.9-2-182
-
C Perlis M Herlyn 2004 Recent advances in melanoma biology Oncologist 9 182 187 15047922 10.1634/theoncologist.9-2-182 (Pubitemid 38452117)
-
(2004)
Oncologist
, vol.9
, Issue.2
, pp. 182-187
-
-
Perlis, C.1
Herlyn, M.2
-
18
-
-
79953326958
-
Targeting BRAF in advanced melanoma: A first step toward manageable disease
-
21447722 10.1158/1078-0432.CCR-10-0174 1:CAS:528:DC%2BC3MXktVOisrw%3D
-
A Vultur J Villanueva M Herlyn 2011 Targeting BRAF in advanced melanoma: a first step toward manageable disease Clin Cancer Res 17 1658 1663 21447722 10.1158/1078-0432.CCR-10-0174 1:CAS:528:DC%2BC3MXktVOisrw%3D
-
(2011)
Clin Cancer Res
, vol.17
, pp. 1658-1663
-
-
Vultur, A.1
Villanueva, J.2
Herlyn, M.3
-
19
-
-
77956513286
-
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
-
20823850 10.1038/nature09454 1:CAS:528:DC%2BC3cXht1ajtbfK
-
G Bollag P Hirth J Tsai J Zhang PN Ibrahim H Cho W Spevak C Zhang Y Zhang G Habets EA Burton B Wong G Tsang BL West B Powell R Shellooe A Marimuthu H Nguyen KY Zhang DR Artis J Schlessinger F Su B Higgins R Iyer K D'Andrea A Koehler M Stumm PS Lin RJ Lee J Grippo I Puzanov KB Kim A Ribas GA McArthur JA Sosman PB Chapman KT Flaherty X Xu KL Nathanson K Nolop 2010 Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma Nature 467 596 599 20823850 10.1038/nature09454 1:CAS:528:DC%2BC3cXht1ajtbfK
-
(2010)
Nature
, vol.467
, pp. 596-599
-
-
Bollag, G.1
Hirth, P.2
Tsai, J.3
Zhang, J.4
Ibrahim, P.N.5
Cho, H.6
Spevak, W.7
Zhang, C.8
Zhang, Y.9
Habets, G.10
Burton, E.A.11
Wong, B.12
Tsang, G.13
West, B.L.14
Powell, B.15
Shellooe, R.16
Marimuthu, A.17
Nguyen, H.18
Zhang, K.Y.19
Artis, D.R.20
Schlessinger, J.21
Su, F.22
Higgins, B.23
Iyer, R.24
D'Andrea, K.25
Koehler, A.26
Stumm, M.27
Lin, P.S.28
Lee, R.J.29
Grippo, J.30
Puzanov, I.31
Kim, K.B.32
Ribas, A.33
McArthur, G.A.34
Sosman, J.A.35
Chapman, P.B.36
Flaherty, K.T.37
Xu, X.38
Nathanson, K.L.39
Nolop, K.40
more..
-
20
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
21639808 10.1056/NEJMoa1103782 1:CAS:528:DC%2BC3MXosVeitbs%3D
-
PB Chapman A Hauschild C Robert JB Haanen P Ascierto J Larkin R Dummer C Garbe A Testori M Maio D Hogg P Lorigan C Lebbe T Jouary D Schadendorf A Ribas SJ O'Day JA Sosman JM Kirkwood AM Eggermont B Dreno K Nolop J Li B Nelson J Hou RJ Lee KT Flaherty AG McArthur 2011 Improved survival with vemurafenib in melanoma with BRAF V600E mutation N Engl J Med 364 2507 2516 21639808 10.1056/NEJMoa1103782 1:CAS:528:DC%2BC3MXosVeitbs%3D
-
(2011)
N Engl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
Haanen, J.B.4
Ascierto, P.5
Larkin, J.6
Dummer, R.7
Garbe, C.8
Testori, A.9
Maio, M.10
Hogg, D.11
Lorigan, P.12
Lebbe, C.13
Jouary, T.14
Schadendorf, D.15
Ribas, A.16
O'Day, S.J.17
Sosman, J.A.18
Kirkwood, J.M.19
Eggermont, A.M.20
Dreno, B.21
Nolop, K.22
Li, J.23
Nelson, B.24
Hou, J.25
Lee, R.J.26
Flaherty, K.T.27
McArthur, A.G.28
more..
-
21
-
-
77949732073
-
RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF
-
20179705 10.1038/nature08902 1:CAS:528:DC%2BC3cXjsFWjsrs%3D
-
PI Poulikakos C Zhang G Bollag KM Shokat N Rosen 2010 RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF Nature 464 427 430 20179705 10.1038/nature08902 1:CAS:528:DC%2BC3cXjsFWjsrs%3D
-
(2010)
Nature
, vol.464
, pp. 427-430
-
-
Poulikakos, P.I.1
Zhang, C.2
Bollag, G.3
Shokat, K.M.4
Rosen, N.5
-
22
-
-
0033161957
-
Haem oxygenase-1 prevents cell death by regulating cellular iron
-
CD Ferris SR Jaffrey A Sawa M Takahashi SD Brady RK Barrow SA Tysoe H Wolosker DE Baranano S Dore KD Poss SH Snyder 1999 Haem oxygenase-1 prevents cell death by regulating cellular iron Nat Cell Biol 1 152 157 10559901 10.1038/11072 1:CAS:528:DyaK1MXks1Ogsb0%3D (Pubitemid 129656019)
-
(1999)
Nature Cell Biology
, vol.1
, Issue.3
, pp. 152-157
-
-
Ferris, C.D.1
Jaffrey, S.R.2
Sawa, A.3
Takahashi, M.4
Brady, S.D.5
Barrow, R.K.6
Tysoe, S.A.7
Wolosker, H.8
Baranano, D.E.9
Dore, S.10
Poss, K.D.11
Snyder, S.H.12
-
23
-
-
0033563729
-
Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore
-
DOI 10.1006/excr.1999.4519
-
N Larochette D Decaudin E Jacotot C Brenner I Marzo SA Susin N Zamzami Z Xie J Reed G Kroemer 1999 Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore Exp Cell Res 249 413 421 10366441 10.1006/excr.1999.4519 1:CAS:528:DyaK1MXjslSlsLo%3D (Pubitemid 29397949)
-
(1999)
Experimental Cell Research
, vol.249
, Issue.2
, pp. 413-421
-
-
Larochette, N.1
Decaudin, D.2
Jacotot, E.3
Brenner, C.4
Marzo, I.5
Susin, S.A.6
Zamzami, N.7
Xie, Z.8
Reed, J.9
Kroemer, G.10
-
24
-
-
77958456360
-
Arsenic trioxide improves event-free and overall survival for adults with acute promyelocytic leukemia: North American Leukemia Intergroup Study C9710
-
20705755 10.1182/blood-2010-02-269621 1:CAS:528:DC%2BC3cXhsFahsLfL
-
BL Powell B Moser W Stock RE Gallagher CL Willman RM Stone JM Rowe S Coutre JH Feusner J Gregory S Couban FR Appelbaum MS Tallman RA Larson 2010 Arsenic trioxide improves event-free and overall survival for adults with acute promyelocytic leukemia: North American Leukemia Intergroup Study C9710 Blood 116 3751 3757 20705755 10.1182/blood-2010-02-269621 1:CAS:528:DC%2BC3cXhsFahsLfL
-
(2010)
Blood
, vol.116
, pp. 3751-3757
-
-
Powell, B.L.1
Moser, B.2
Stock, W.3
Gallagher, R.E.4
Willman, C.L.5
Stone, R.M.6
Rowe, J.M.7
Coutre, S.8
Feusner, J.H.9
Gregory, J.10
Couban, S.11
Appelbaum, F.R.12
Tallman, M.S.13
Larson, R.A.14
-
25
-
-
0345505337
-
Low-level arsenite induced gene expression in HEK293 cells
-
DOI 10.1016/S0300-483X(03)00025-8
-
XH Zheng GS Watts S Vaught AJ Gandolfi 2003 Low-level arsenite induced gene expression in HEK293 cells Toxicology 187 39 48 12679051 10.1016/S0300-483X(03)00025-8 1:CAS:528:DC%2BD3sXisFSls7w%3D (Pubitemid 36388757)
-
(2003)
Toxicology
, vol.187
, Issue.1
, pp. 39-48
-
-
Zheng, X.H.1
Watts, G.S.2
Vaught, S.3
Gandolfi, A.J.4
-
26
-
-
49049086338
-
Ligand-based targeting of apoptosis in cancer: The potential of recombinant human apoptosis ligand 2/tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL)
-
18640940 10.1200/JCO.2007.15.7198 1:CAS:528:DC%2BD1cXpvVWmtbw%3D
-
A Ashkenazi P Holland SG Eckhardt 2008 Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL) J Clin Oncol 26 3621 3630 18640940 10.1200/JCO.2007.15.7198 1:CAS:528:DC%2BD1cXpvVWmtbw%3D
-
(2008)
J Clin Oncol
, vol.26
, pp. 3621-3630
-
-
Ashkenazi, A.1
Holland, P.2
Eckhardt, S.G.3
-
27
-
-
33846448142
-
Cholesterol, statins and cancer
-
DOI 10.1111/j.1440-1681.2007.04565.x
-
AJ Brown 2007 Cholesterol, statins and cancer Clin Exp Pharmacol Physiol 34 135 141 17250629 10.1111/j.1440-1681.2007.04565.x 1:CAS:528: DC%2BD2sXhvFWntLo%3D (Pubitemid 46148252)
-
(2007)
Clinical and Experimental Pharmacology and Physiology
, vol.34
, Issue.3
, pp. 135-141
-
-
Brown, A.J.1
-
28
-
-
69249219178
-
Targeting the mevalonate pathway for improved anticancer therapy
-
19508172 10.2174/156800909789057033 1:CAS:528:DC%2BD1MXhtFehtb7O
-
G Fritz 2009 Targeting the mevalonate pathway for improved anticancer therapy Curr Cancer Drug Targets 9 626 638 19508172 10.2174/156800909789057033 1:CAS:528:DC%2BD1MXhtFehtb7O
-
(2009)
Curr Cancer Drug Targets
, vol.9
, pp. 626-638
-
-
Fritz, G.1
-
29
-
-
31844451010
-
Anti-inflammatory effects of statins: Clinical evidence and basic mechanisms
-
16341063 10.1038/nrd1901 1:CAS:528:DC%2BD2MXht1yktbjP
-
MK Jain PM Ridker 2005 Anti-inflammatory effects of statins: clinical evidence and basic mechanisms Nat Rev Drug Discov 4 977 987 16341063 10.1038/nrd1901 1:CAS:528:DC%2BD2MXht1yktbjP
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 977-987
-
-
Jain, M.K.1
Ridker, P.M.2
-
30
-
-
33646051204
-
Dual treatment with COX-2 inhibitor and sodium arsenite leads to induction of surface Fas Ligand expression and Fas-Ligand-mediated apoptosis in human melanoma cells
-
16487513 10.1016/j.yexcr.2006.01.003 1:CAS:528:DC%2BD28Xjs1ajtrk%3D
-
VN Ivanov TK Hei 2006 Dual treatment with COX-2 inhibitor and sodium arsenite leads to induction of surface Fas Ligand expression and Fas-Ligand-mediated apoptosis in human melanoma cells Exp Cell Res 312 1401 1417 16487513 10.1016/j.yexcr.2006.01.003 1:CAS:528:DC%2BD28Xjs1ajtrk%3D
-
(2006)
Exp Cell Res
, vol.312
, pp. 1401-1417
-
-
Ivanov, V.N.1
Hei, T.K.2
-
31
-
-
67651174743
-
Simvastatin attenuates microglial cells and astrocyte activation and decreases interleukin-1beta level after traumatic brain injury
-
19574840 10.1227/01.NEU.0000346272.76537.DC
-
B Li A Mahmood D Lu H Wu Y Xiong C Qu M Chopp 2009 Simvastatin attenuates microglial cells and astrocyte activation and decreases interleukin-1beta level after traumatic brain injury Neurosurgery 65 179 185 19574840 10.1227/01.NEU.0000346272.76537.DC
-
(2009)
Neurosurgery
, vol.65
, pp. 179-185
-
-
Li, B.1
Mahmood, A.2
Lu, D.3
Wu, H.4
Xiong, Y.5
Qu, C.6
Chopp, M.7
-
32
-
-
0038001179
-
ERK and PI3K negatively regulate STAT-transcriptional activities in human melanoma cells: Implications towards sensitization to apoptosis
-
DOI 10.1038/sj.onc.1206598
-
M Krasilnikov VN Ivanov J Dong Z Ronai 2003 ERK and PI3K negatively regulate STAT-transcriptional activities in human melanoma cells: implications towards sensitization to apoptosis Oncogene 22 4092 4101 12821943 10.1038/sj.onc.1206598 1:CAS:528:DC%2BD3sXkvVSls74%3D (Pubitemid 36819649)
-
(2003)
Oncogene
, vol.22
, Issue.26
, pp. 4092-4101
-
-
Krasilnikov, M.1
Ivanov, V.N.2
Dong, J.3
Ronai, Z.4
-
33
-
-
39549088497
-
Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression
-
18222423 10.1016/j.yexcr.2007.12.012 1:CAS:528:DC%2BD1cXisVWjtbg%3D
-
VN Ivanov MA Partridge GE Johnson SX Huang H Zhou TK Hei 2008 Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression Exp Cell Res 314 1163 1176 18222423 10.1016/j.yexcr.2007.12.012 1:CAS:528:DC%2BD1cXisVWjtbg%3D
-
(2008)
Exp Cell Res
, vol.314
, pp. 1163-1176
-
-
Ivanov, V.N.1
Partridge, M.A.2
Johnson, G.E.3
Huang, S.X.4
Zhou, H.5
Hei, T.K.6
-
34
-
-
77953479620
-
Disruption of IGF-1R signaling increases TRAIL-induced apoptosis: A new potential therapy for the treatment of melanoma
-
20417200 10.1016/j.yexcr.2010.04.014 1:CAS:528:DC%2BC3cXmslGht7s%3D
-
TB Karasic TK Hei VN Ivanov 2010 Disruption of IGF-1R signaling increases TRAIL-induced apoptosis: a new potential therapy for the treatment of melanoma Exp Cell Res 316 1994 2007 20417200 10.1016/j.yexcr.2010.04.014 1:CAS:528:DC%2BC3cXmslGht7s%3D
-
(2010)
Exp Cell Res
, vol.316
, pp. 1994-2007
-
-
Karasic, T.B.1
Hei, T.K.2
Ivanov, V.N.3
-
35
-
-
34347253556
-
TRAIL: A multifunctional cytokine
-
17485341 10.2741/2354 1:CAS:528:DC%2BD2sXms1Kmu7w%3D
-
U Schaefer O Voloshanenko D Willen H Walczak 2007 TRAIL: a multifunctional cytokine Front Biosci 12 3813 3824 17485341 10.2741/2354 1:CAS:528:DC%2BD2sXms1Kmu7w%3D
-
(2007)
Front Biosci
, vol.12
, pp. 3813-3824
-
-
Schaefer, U.1
Voloshanenko, O.2
Willen, D.3
Walczak, H.4
-
36
-
-
70349339634
-
Functional neurons and melanocytes induced from immortal lines of postnatal neural crest-like stem cells
-
19447881 10.1096/fj.08-123596 1:CAS:528:DC%2BD1MXhtFagsrbO
-
EV Sviderskaya DJ Easty MA Lawrence DP Sanchez YA Negulyaev RH Patel P Anand YE Korchev DC Bennett 2009 Functional neurons and melanocytes induced from immortal lines of postnatal neural crest-like stem cells FASEB J 23 3179 3192 19447881 10.1096/fj.08-123596 1:CAS:528:DC%2BD1MXhtFagsrbO
-
(2009)
FASEB J
, vol.23
, pp. 3179-3192
-
-
Sviderskaya, E.V.1
Easty, D.J.2
Lawrence, M.A.3
Sanchez, D.P.4
Negulyaev, Y.A.5
Patel, R.H.6
Anand, P.7
Korchev, Y.E.8
Bennett, D.C.9
-
37
-
-
66149090765
-
Molecular pathogenesis of cutaneous melanocytic neoplasms
-
10.1146/annurev.pathol.3.121806.151541 1:CAS:528:DC%2BD1MXis1ahsrk%3D
-
N Ibrahim FG Haluska 2009 Molecular pathogenesis of cutaneous melanocytic neoplasms Ann Rev Pathol Mech Dis 4 551 579 10.1146/annurev.pathol.3.121806. 151541 1:CAS:528:DC%2BD1MXis1ahsrk%3D
-
(2009)
Ann Rev Pathol Mech Dis
, vol.4
, pp. 551-579
-
-
Ibrahim, N.1
Haluska, F.G.2
-
38
-
-
78650303507
-
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
-
21107323 10.1038/nature09626 1:CAS:528:DC%2BC3cXhsVOrsbjI
-
R Nazarian H Shi Q Wang X Kong RC Koya H Lee Z Chen M-K Lee N Attar H Sazegar T Chodon SF Nelson G McArthur JA Sosman A Ribas RS Lo 2010 Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation Nature 468 973 977 21107323 10.1038/nature09626 1:CAS:528:DC%2BC3cXhsVOrsbjI
-
(2010)
Nature
, vol.468
, pp. 973-977
-
-
Nazarian, R.1
Shi, H.2
Wang, Q.3
Kong, X.4
Koya, R.C.5
Lee, H.6
Chen, Z.7
Lee, M.-K.8
Attar, N.9
Sazegar, H.10
Chodon, T.11
Nelson, S.F.12
McArthur, G.13
Sosman, J.A.14
Ribas, A.15
Lo, R.S.16
-
39
-
-
78650373172
-
Drug discovery: How melanomas bypass new therapy
-
21164474 10.1038/468902a 1:CAS:528:DC%2BC3cXhsFKmu7nF
-
D Solit CL Sawyers 2010 Drug discovery: how melanomas bypass new therapy Nature 468 902 903 21164474 10.1038/468902a 1:CAS:528:DC%2BC3cXhsFKmu7nF
-
(2010)
Nature
, vol.468
, pp. 902-903
-
-
Solit, D.1
Sawyers, C.L.2
-
40
-
-
0034680928
-
Inhibition of NF-kappa B activation by arsenite through reaction with a critical cysteine in the activation loop of Ikappa B kinase
-
10967126 10.1074/jbc.M007204200 1:CAS:528:DC%2BD3cXosVSkurw%3D
-
P Kapahi T Takahashi G Natoli SR Adams Y Chen RY Tsien M Karin 2000 Inhibition of NF-kappa B activation by arsenite through reaction with a critical cysteine in the activation loop of Ikappa B kinase J Biol Chem 275 36062 36066 10967126 10.1074/jbc.M007204200 1:CAS:528:DC%2BD3cXosVSkurw%3D
-
(2000)
J Biol Chem
, vol.275
, pp. 36062-36066
-
-
Kapahi, P.1
Takahashi, T.2
Natoli, G.3
Adams, S.R.4
Chen, Y.5
Tsien, R.Y.6
Karin, M.7
-
41
-
-
34249773993
-
Modulation of COX-2 expression by statins in human monocytic cells
-
DOI 10.1096/fj.06-6766com
-
Ad Habib I Shamseddeen MS Nasrallah TA Antoun G Nemer J Bertoglio R Badreddine KF Badr 2007 Modulation of COX-2 expression by statins in human monocytic cells FASEB J 21 1665 1674 17317725 10.1096/fj.06-6766com 1:CAS:528:DC%2BD2sXmsVWlu7w%3D (Pubitemid 46855612)
-
(2007)
FASEB Journal
, vol.21
, Issue.8
, pp. 1665-1674
-
-
Habib, A.1
Shamseddeen, I.2
Nasrallah, M.S.3
Antoun, T.A.4
Nemer, G.5
Bertoglio, J.6
Badreddine, R.7
Badr, K.F.8
-
42
-
-
51449084384
-
Apoptosome-deficient cells lose cytochrome c through proteasomal degradation but survive by autophagy-dependent glycolysis
-
18550800 10.1091/mbc.E07-09-0858 1:CAS:528:DC%2BD1cXpvV2hsb8%3D
-
E Ferraro A Pulicati MT Cencioni M Cozzolino F Navoni S di Martino R Nardacci MT Carri F Cecconi 2008 Apoptosome-deficient cells lose cytochrome c through proteasomal degradation but survive by autophagy-dependent glycolysis Mol Biol Cell 19 3576 3588 18550800 10.1091/mbc.E07-09-0858 1:CAS:528: DC%2BD1cXpvV2hsb8%3D
-
(2008)
Mol Biol Cell
, vol.19
, pp. 3576-3588
-
-
Ferraro, E.1
Pulicati, A.2
Cencioni, M.T.3
Cozzolino, M.4
Navoni, F.5
Di Martino, S.6
Nardacci, R.7
Carri, M.T.8
Cecconi, F.9
-
43
-
-
33745863017
-
Drug Insight: Cancer therapy strategies based on restoration of endogenous cell death mechanisms
-
DOI 10.1038/ncponc0538, PII NCPONC0538
-
JC Reed 2006 Drug insight: cancer therapy strategies based on restoration of endogenous cell death mechanisms Nat Clin Pract Oncol 3 388 398 16826219 10.1038/ncponc0538 1:CAS:528:DC%2BD28XotVektrY%3D (Pubitemid 44027293)
-
(2006)
Nature Clinical Practice Oncology
, vol.3
, Issue.7
, pp. 388-398
-
-
Reed, J.C.1
-
44
-
-
40849114654
-
Simvastatin inhibits growth via apoptosis and the induction of cell cycle arrest in human melanoma cells
-
DOI 10.1097/CMR.0b013e3282f60097, PII 0000839020080400000002
-
A Saito N Saito W Mol H Furukawa A Tsutsumida A Oyama M Sekido S Sasaki Y Yamamoto 2008 Simvastatin inhibits growth via apoptosis and the induction of cell cycle arrest in human melanoma cells Melanoma Res 18 85 94 18337644 10.1097/CMR.0b013e3282f60097 1:CAS:528:DC%2BD1cXjt1ertb0%3D (Pubitemid 351398262)
-
(2008)
Melanoma Research
, vol.18
, Issue.2
, pp. 85-94
-
-
Saito, A.1
Saito, N.2
Mol, W.3
Furukawa, H.4
Tsutsumida, A.5
Oyama, A.6
Sekido, M.7
Sasaki, S.8
Yamamoto, Y.9
-
45
-
-
78650108941
-
Simvastatin impairs murine melanoma growth
-
21162733 10.1186/1476-511X-9-142 1:CAS:528:DC%2BC3cXhs1WqsbjN
-
GM Favero MF Otuki KA Oliveira MS Bohatch Jr P Borelli FE Barros DA Maria D Fernandes SP Bydlowski 2010 Simvastatin impairs murine melanoma growth Lipids Health Dis 9 142 149 21162733 10.1186/1476-511X-9-142 1:CAS:528: DC%2BC3cXhs1WqsbjN
-
(2010)
Lipids Health Dis
, vol.9
, pp. 142-149
-
-
Favero, G.M.1
Otuki, M.F.2
Oliveira, K.A.3
Bohatch, Jr.M.S.4
Borelli, P.5
Barros, F.E.6
Maria, D.A.7
Fernandes, D.8
Bydlowski, S.P.9
-
46
-
-
75049085880
-
Can statin therapy reduce the risk of melanoma? A meta-analysis of randomized controlled trials
-
19844794 10.1007/s10654-009-9396-x 1:CAS:528:DC%2BC3cXnt1agsg%3D%3D
-
S Bonovas G Nikolopoulos K Filioussi E Peponi P Bagos NM Sitaras 2010 Can statin therapy reduce the risk of melanoma? A meta-analysis of randomized controlled trials Eur J Epidemiol 25 29 35 19844794 10.1007/s10654-009-9396-x 1:CAS:528:DC%2BC3cXnt1agsg%3D%3D
-
(2010)
Eur J Epidemiol
, vol.25
, pp. 29-35
-
-
Bonovas, S.1
Nikolopoulos, G.2
Filioussi, K.3
Peponi, E.4
Bagos, P.5
Sitaras, N.M.6
-
47
-
-
79958853173
-
Long-term use of nonsteroidal anti-inflammatory drugs decreases the risk of cutaneous melanoma: Results of a United States case-control study
-
21390049 10.1038/jid.2011.58 1:CAS:528:DC%2BC3MXnsFWgs7Y%3D
-
C Curiel-Lewandrowski T Nijsten ML Gomez LM Hollestein MB Atkins RS Stern 2011 Long-term use of nonsteroidal anti-inflammatory drugs decreases the risk of cutaneous melanoma: results of a United States case-control study J Invest Dermatol 131 1460 1468 21390049 10.1038/jid.2011.58 1:CAS:528: DC%2BC3MXnsFWgs7Y%3D
-
(2011)
J Invest Dermatol
, vol.131
, pp. 1460-1468
-
-
Curiel-Lewandrowski, C.1
Nijsten, T.2
Gomez, M.L.3
Hollestein, L.M.4
Atkins, M.B.5
Stern, R.S.6
-
48
-
-
0037429617
-
Risk for myopathy with statin therapy in high-risk patients
-
DOI 10.1001/archinte.163.5.553
-
CM Ballantyne A Corsini MH Davidson H Holdaas TA Jacobson E Leitersdorf W Marz JP Reckless EA Stein 2003 Risk for myopathy with statin therapy in high-risk patients Arch Intern Med 163 553 564 12622602 10.1001/archinte.163.5. 553 1:CAS:528:DC%2BD3sXis1elurw%3D (Pubitemid 36314342)
-
(2003)
Archives of Internal Medicine
, vol.163
, Issue.5
, pp. 553-564
-
-
Ballantyne, C.M.1
Corsini, A.2
Davidson, M.H.3
Holdaas, H.4
Jacobson, T.A.5
Leitersdorf, E.6
Marz, W.7
Reckless, J.P.D.8
Stein, E.A.9
-
49
-
-
77953859606
-
NF-kappaB as a critical link between inflammation and cancer
-
10.1101/cshperspect.a000141
-
M Karin 2010 NF-kappaB as a critical link between inflammation and cancer Cold Spring Harb Perspect Biol 1 a000141 10.1101/cshperspect.a000141
-
(2010)
Cold Spring Harb Perspect Biol
, vol.1
, pp. 000141
-
-
Karin, M.1
-
50
-
-
1642576201
-
Sensitization for Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis by the Chemopreventive Agent Resveratrol
-
DOI 10.1158/0008-5472.CAN-03-1656
-
S Fulda KM Debatin 2004 Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol Cancer Res 64 337 346 14729643 10.1158/0008-5472.CAN-03-1656 1:CAS:528:DC%2BD2cXkslyrsA%3D%3D (Pubitemid 38114116)
-
(2004)
Cancer Research
, vol.64
, Issue.1
, pp. 337-346
-
-
Fulda, S.1
Debatin, K.-M.2
-
51
-
-
71549171910
-
Curcumin potentiates the antitumor effects of Bacillus Calmette-Guerin against bladder cancer through the downregulation of NF-κB and upregulation of TRAIL receptors
-
19903839 10.1158/0008-5472.CAN-09-2045 1:CAS:528:DC%2BD1MXhsV2itLjM
-
AM Kamat ST Tharakan B Sung BB Aggarwal 2009 Curcumin potentiates the antitumor effects of Bacillus Calmette-Guerin against bladder cancer through the downregulation of NF-κB and upregulation of TRAIL receptors Cancer Res 69 8958 8966 19903839 10.1158/0008-5472.CAN-09-2045 1:CAS:528:DC%2BD1MXhsV2itLjM
-
(2009)
Cancer Res
, vol.69
, pp. 8958-8966
-
-
Kamat, A.M.1
Tharakan, S.T.2
Sung, B.3
Aggarwal, B.B.4
-
52
-
-
38049034969
-
Lovastatin sensitized human glioblastoma cells to TRAIL-induced apoptosis
-
17928957 10.1007/s11060-007-9475-3 1:CAS:528:DC%2BD1cXivVKrtr4%3D
-
DY Chan GG Chen WS Poon PC Liu 2008 Lovastatin sensitized human glioblastoma cells to TRAIL-induced apoptosis J Neurooncol 86 273 283 17928957 10.1007/s11060-007-9475-3 1:CAS:528:DC%2BD1cXivVKrtr4%3D
-
(2008)
J Neurooncol
, vol.86
, pp. 273-283
-
-
Chan, D.Y.1
Chen, G.G.2
Poon, W.S.3
Liu, P.C.4
-
53
-
-
0034283536
-
Inhibitors of HMG-CoA reductase sensitize human smooth muscle cells to Fas-ligand and cytokine-induced cell death
-
10996358 10.1016/S0021-9150(99)00462-1 1:CAS:528:DC%2BD3cXmtlGqur8%3D
-
AC Knapp J Huang G Starling PA Kiener 2000 Inhibitors of HMG-CoA reductase sensitize human smooth muscle cells to Fas-ligand and cytokine-induced cell death Atherosclerosis 152 217 227 10996358 10.1016/S0021-9150(99)00462-1 1:CAS:528:DC%2BD3cXmtlGqur8%3D
-
(2000)
Atherosclerosis
, vol.152
, pp. 217-227
-
-
Knapp, A.C.1
Huang, J.2
Starling, G.3
Kiener, P.A.4
-
54
-
-
0345549483
-
Cyclooxygenase-2 (COX-2) inhibitors sensitize tumor cells specifically to death receptor-induced apoptosis independently of COX-2 inhibition
-
DOI 10.1038/sj.onc.1206837
-
G Totzke K Schulze-Osthoff RU Janicke 2003 Cyclooxygenase-2 (COX-2) inhibitors sensitize tumor cells specifically to death receptor-induced apoptosis independently of COX-2 inhibition Oncogene 22 8021 8030 12970750 10.1038/sj.onc.1206837 (Pubitemid 37175866)
-
(2003)
Oncogene
, vol.22
, Issue.39
, pp. 8021-8030
-
-
Totzke, G.1
Schulze-Osthoff, K.2
Janicke, R.U.3
-
55
-
-
39749120859
-
The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells
-
DOI 10.1186/1471-2407-8-9
-
SA Glynn D O'Sullivan AJ Eustace M Clynes N O'Donovan 2008 The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells BMC Cancer 8 9 18199328 10.1186/1471-2407-8-9 (Pubitemid 351309029)
-
(2008)
BMC Cancer
, vol.8
, pp. 9
-
-
Glynn, S.A.1
O'Sullivan, D.2
Eustace, A.J.3
Clynes, M.4
O'Donovan, N.5
-
56
-
-
70350335298
-
Autocrine amplification loop in statin-induced apoptosis of human melanoma cells
-
19563533 10.1111/j.1476-5381.2009.00298.x 1:CAS:528:DC%2BD1MXhtVelt7fM
-
C Minichsdorfer M Hohenegger 2009 Autocrine amplification loop in statin-induced apoptosis of human melanoma cells Br J Pharmacol 157 1278 1290 19563533 10.1111/j.1476-5381.2009.00298.x 1:CAS:528:DC%2BD1MXhtVelt7fM
-
(2009)
Br J Pharmacol
, vol.157
, pp. 1278-1290
-
-
Minichsdorfer, C.1
Hohenegger, M.2
-
57
-
-
34249945646
-
Arsenic trioxide and neuroblastoma cytotoxicity
-
DOI 10.1007/s10863-006-9058-6, The Cancer Cell's Power Plants as Promising Therapeutic Targets
-
H Pettersson J Karlsson A Pietras I ∅ra S Påhlman 2007 Arsenic trioxide and neuroblastoma cytotoxicity J Bioenerg Biomembr 39 35 41 17549641 10.1007/s10863-006-9058-6 1:CAS:528:DC%2BD2sXmtFentro%3D (Pubitemid 46877171)
-
(2007)
Journal of Bioenergetics and Biomembranes
, vol.39
, Issue.1
, pp. 35-41
-
-
Pettersson, H.M.1
Karlsson, J.2
Pietras, A.3
Ora, I.4
Pahlman, S.5
-
58
-
-
0030853288
-
Melanoma cell lines from different stages of progression and their biological and molecular analyses
-
K Satyamoorthy E DeJesus AJ Linnenbach B Kraj DL Kornreich S Rendle DE Elder M Herlyn 1997 Melanoma cell lines from different stages of progression and their biological and molecular analyses Melanoma Res 7 Suppl 2 S35 S42 9578415 1:CAS:528:DyaK2sXnsV2is7w%3D (Pubitemid 27501624)
-
(1997)
Melanoma Research
, vol.7
, Issue.SUPPL. 2
-
-
Satyamoorthy, K.1
DeJesus, E.2
Linnenbach, A.J.3
Kraj, B.4
Kornreich, D.L.5
Rendle, S.6
Elder, D.E.7
Herlyn, M.8
-
59
-
-
0028154837
-
Nude rat models for human tumor metastasis to CNS. Procedures for intracarotid delivery of cancer cells and drugs
-
DOI 10.1007/BF01063770
-
AT Myklebust A Helseth K Breistol WA Hall O Fodstad 1994 Nude rat models for human tumor metastasis to CNS. Procedures for intracarotid delivery of cancer cells and drugs J Neurooncol 21 215 224 7699416 10.1007/BF01063770 1:STN:280:DyaK2M3htlOltw%3D%3D (Pubitemid 24381470)
-
(1994)
Journal of Neuro-Oncology
, vol.21
, Issue.3
, pp. 215-224
-
-
Myklebust, A.T.1
Helseth, A.2
Breistol, K.3
Hall, W.A.4
Fodstad, O.5
|