메뉴 건너뛰기




Volumn 4, Issue 3, 2010, Pages 285-291

Value of mucosal assessment and biomarkers in inflammatory bowel disease

Author keywords

Biomarker; C reactive protein; Crohns disease; Fecal calprotectin; Fecal lactoferrin; Inflammatory bowel disease; Mucosal healing; Outcome; Ulcerative colitis

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; CALGRANULIN; INFLIXIMAB; INTERLEUKIN 6; LACTOFERRIN; PROTEIN S 100; PROTEIN S100A12; TUMOR NECROSIS FACTOR ALPHA; UBE4A PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

EID: 77953278068     PISSN: 17474124     EISSN: None     Source Type: Journal    
DOI: 10.1586/egh.10.22     Document Type: Review
Times cited : (16)

References (55)
  • 1
    • 33144463875 scopus 로고    scopus 로고
    • European evidence based consensus on the diagnosis and management of Crohn's disease: Special situations
    • Caprilli R, Gassull MA, Escher JC et al. European evidence based consensus on the diagnosis and management of Crohn's disease: special situations. Gut 55(Suppl. 1), i36-i58 (2006).
    • (2006) Gut , vol.55 , Issue.SUPPL. 1
    • Caprilli, R.1    Gassull, M.A.2    Escher, J.C.3
  • 2
    • 0030698094 scopus 로고    scopus 로고
    • Practice parameters for the treatment of mucosal ulcerative colitis - Supporting documentation
    • The Standards Practice Task Force. The American Society of Colon and Rectal Surgeons
    • Wexner SD, Rosen L, Lowry A et al. Practice parameters for the treatment of mucosal ulcerative colitis - supporting documentation. The Standards Practice Task Force. The American Society of Colon and Rectal Surgeons. Dis. Colon Rectum 40(11), 1277-1285 (1997).
    • (1997) Dis. Colon Rectum , vol.40 , Issue.11 , pp. 1277-1285
    • Wexner, S.D.1    Rosen, L.2    Lowry, A.3
  • 4
    • 57249103566 scopus 로고    scopus 로고
    • Direct health care costs of Crohn's disease and ulcerative colitis in US children and adults
    • Kappelman MD, Rifas-Shiman SL, Porter CQ et al. Direct health care costs of Crohn's disease and ulcerative colitis in US children and adults. Gastroenterology 135(6), 1907-1913 (2008).
    • (2008) Gastroenterology , vol.135 , Issue.6 , pp. 1907-1913
    • Kappelman, M.D.1    Rifas-Shiman, S.L.2    Porter, C.Q.3
  • 5
    • 34648839566 scopus 로고    scopus 로고
    • Sustained improvement of health-related quality of life in Crohn's disease patients treated with infliximab and azathioprine for 4 years
    • Casellas F, Rodrigo L, Nino P, Pantiga C, Riestra S, Malagelada JR. Sustained improvement of health-related quality of life in Crohn's disease patients treated with infliximab and azathioprine for 4 years. Inflamm. Bowel Dis. 13(11), 1395-1400 (2007).
    • (2007) Inflamm. Bowel Dis , vol.13 , Issue.11 , pp. 1395-1400
    • Casellas, F.1    Rodrigo, L.2    Nino, P.3    Pantiga, C.4    Riestra, S.5    Malagelada, J.R.6
  • 6
    • 0030041584 scopus 로고    scopus 로고
    • Long-term follow-up of patients with Crohn's disease treated with azathioprine or 6-mercaptopurine
    • Bouhnik Y, Lemann M, Mary JY et al. Long-term follow-up of patients with Crohn's disease treated with azathioprine or 6-mercaptopurine. Lancet 347(8996), 215-219 (1996).
    • (1996) Lancet , vol.347 , Issue.8996 , pp. 215-219
    • Bouhnik, Y.1    Lemann, M.2    Mary, J.Y.3
  • 7
    • 36549071038 scopus 로고    scopus 로고
    • Clinical course in Crohn's disease: Results of a Norwegian population-based ten-year follow-up study
    • Solberg IC, Vatn MH, Hoie O et al. Clinical course in Crohn's disease: results of a Norwegian population-based ten-year follow-up study. Clin. Gastroenterol. Hepatol. 5(12), 1430-1438 (2007).
    • (2007) Clin. Gastroenterol. Hepatol , vol.5 , Issue.12 , pp. 1430-1438
    • Solberg, I.C.1    Vatn, M.H.2    Hoie, O.3
  • 8
    • 0036061640 scopus 로고    scopus 로고
    • Long-term evolution of disease behavior of Crohn's disease
    • Cosnes J, Cattan S, Blain A et al. Long-term evolution of disease behavior of Crohn's disease. Inflamm. Bowel Dis. 8(4), 244-250 (2002).
    • (2002) Inflamm. Bowel Dis , vol.8 , Issue.4 , pp. 244-250
    • Cosnes, J.1    Cattan, S.2    Blain, A.3
  • 9
    • 55149124689 scopus 로고    scopus 로고
    • Infliximab for inflammatory bowel disease in Denmark 1999- 2005: Clinical outcome and follow-up evaluation of malignancy and mortality
    • quiz 1176
    • Caspersen S, Elkjaer M, Riis L et al. Infliximab for inflammatory bowel disease in Denmark 1999-2005: clinical outcome and follow-up evaluation of malignancy and mortality. Clin. Gastroenterol. Hepatol. 6(11), 1212-1217; quiz 1176 (2008).
    • (2008) Clin. Gastroenterol. Hepatol , vol.6 , Issue.11 , pp. 1212-1217
    • Caspersen, S.1    Elkjaer, M.2    Riis, L.3
  • 10
    • 58149098406 scopus 로고    scopus 로고
    • The safety profile of anti-tumour necrosis factor therapy in inflammatory bowel disease in clinical practice: Analysis of 620 patient-years follow-up
    • Lees CW, Ali AI, Thompson AI et al. The safety profile of anti-tumour necrosis factor therapy in inflammatory bowel disease in clinical practice: analysis of 620 patient-years follow-up. Aliment. Pharmacol. Ther. 29(3), 286-297 (2009).
    • (2009) Aliment. Pharmacol. Ther , vol.29 , Issue.3 , pp. 286-297
    • Lees, C.W.1    Ali, A.I.2    Thompson, A.I.3
  • 11
    • 33744808274 scopus 로고    scopus 로고
    • Nodular regenerative hyperplasia: A reversible entity associated with azathioprine therapy
    • Seiderer J, Zech CJ, Diebold J et al. Nodular regenerative hyperplasia: a reversible entity associated with azathioprine therapy. Eur. J. Gastroenterol. Hepatol. 18(5), 553-555 (2006).
    • (2006) Eur. J. Gastroenterol. Hepatol , vol.18 , Issue.5 , pp. 553-555
    • Seiderer, J.1    Zech, C.J.2    Diebold, J.3
  • 12
    • 41349088375 scopus 로고    scopus 로고
    • Risk factors for opportunistic infections in patients with inflammatory bowel disease
    • Toruner M, Loftus EV Jr, Harmsen WS et al. Risk factors for opportunistic infections in patients with inflammatory bowel disease. Gastroenterology 134(4), 929-936 (2008).
    • (2008) Gastroenterology , vol.134 , Issue.4 , pp. 929-936
    • Toruner, M.1    Loftus Jr., E.V.2    Harmsen, W.S.3
  • 13
    • 0036120291 scopus 로고    scopus 로고
    • Long term outcome of patients with active Crohn's disease exhibiting extensive and deep ulcerations at colonoscopy
    • Allez M, Lemann M, Bonnet J, Cattan P, Jian R, Modigliani R. Long term outcome of patients with active Crohn's disease exhibiting extensive and deep ulcerations at colonoscopy. Am. J. Gastroenterol. 97(4), 947-953 (2002).
    • (2002) Am. J. Gastroenterol , vol.97 , Issue.4 , pp. 947-953
    • Allez, M.1    Lemann, M.2    Bonnet, J.3    Cattan, P.4    Jian, R.5    Modigliani, R.6
  • 15
    • 85069275036 scopus 로고    scopus 로고
    • Prediction of long-term clinical remission for adalimumab-treated patients with Crohn's disease by identification of approriate dichotomizing points for SES-CD
    • Presented at: , American Gastroenterological Association. New Orleans, LA, USA 1-5 May Abstract 41a
    • Reinisch W, Rutgeerts PJ, Panaccione R et al. Prediction of long-term clinical remission for adalimumab-treated patients with Crohn's disease by identification of approriate dichotomizing points for SES-CD. Presented at: Digestive Disease Week 2010, American Gastroenterological Association. New Orleans, LA, USA, 1-5 May, 2010 (Abstract 41a).
    • (2010) Digestive Disease Week 2010
    • Reinisch, W.1    Rutgeerts, P.J.2    Panaccione, R.3
  • 16
    • 34547503869 scopus 로고    scopus 로고
    • Mucosal healing in inflammatory bowel disease: Results from a Norwegian population-based cohort
    • Froslie KF, Jahnsen J, Moum BA, Vatn MH. Mucosal healing in inflammatory bowel disease: results from a Norwegian population-based cohort. Gastroenterology 133(2), 412-422 (2007).
    • (2007) Gastroenterology , vol.133 , Issue.2 , pp. 412-422
    • Froslie, K.F.1    Jahnsen, J.2    Moum, B.A.3    Vatn, M.H.4
  • 17
    • 75449114677 scopus 로고    scopus 로고
    • Mucosal healing predicts sustained clinical remission in patients with early-stage Crohn's disease
    • Baert F, Moortgat L, Van Assche G et al. Mucosal healing predicts sustained clinical remission in patients with early-stage Crohn's disease. Gastroenterology 138(2), 463-468 (2010).
    • (2010) Gastroenterology , vol.138 , Issue.2 , pp. 463-468
    • Baert, F.1    Moortgat, L.2    Van Assche, G.3
  • 18
    • 70350172248 scopus 로고    scopus 로고
    • Mucosal healing predicts long-term outcome of maintenance therapy with infliximab in Crohn's disease
    • Schnitzler F, Fidder H, Ferrante M et al. Mucosal healing predicts long-term outcome of maintenance therapy with infliximab in Crohn's disease. Inflamm. Bowel Dis. 15(9), 1295-1301 (2009).
    • (2009) Inflamm. Bowel Dis , vol.15 , Issue.9 , pp. 1295-1301
    • Schnitzler, F.1    Fidder, H.2    Ferrante, M.3
  • 19
    • 33645029146 scopus 로고    scopus 로고
    • Multi-detector CT-colonography in inflammatory bowel disease: Prospective analysis of CT-findings to high-resolution video colonoscopy
    • Andersen K, Vogt C, Blondin D et al. Multi-detector CT-colonography in inflammatory bowel disease: prospective analysis of CT-findings to high-resolution video colonoscopy. Eur. J. Radiol. 58(1), 140-146 (2006).
    • (2006) Eur. J. Radiol , vol.58 , Issue.1 , pp. 140-146
    • Andersen, K.1    Vogt, C.2    Blondin, D.3
  • 20
    • 62149135323 scopus 로고    scopus 로고
    • Magnetic resonance colonography for the evaluation of colonic inflammatory bowel disease: Correlation with conventional colonoscopy
    • Ergen FB, Akata D, Hayran M et al. Magnetic resonance colonography for the evaluation of colonic inflammatory bowel disease: correlation with conventional colonoscopy. J. Comput. Assist. Tomogr. 32(6), 848-854 (2008).
    • (2008) J. Comput. Assist. Tomogr , vol.32 , Issue.6 , pp. 848-854
    • Ergen, F.B.1    Akata, D.2    Hayran, M.3
  • 21
    • 73949083566 scopus 로고    scopus 로고
    • Endoscopy and MR enteroclysis: Equivalent tools in predicting clinical recurrence in patients with Crohn's disease after ileocolic resection
    • Koilakou S, Sailer J, Peloschek P et al. Endoscopy and MR enteroclysis: Equivalent tools in predicting clinical recurrence in patients with Crohn's disease after ileocolic resection. Inflamm. Bowel Dis. 16(2), 198-203 (2009).
    • (2009) Inflamm. Bowel Dis , vol.16 , Issue.2 , pp. 198-203
    • Koilakou, S.1    Sailer, J.2    Peloschek, P.3
  • 22
    • 0028158882 scopus 로고
    • Ultrasonography as a primary diagnostic tool in patients with inflammatory disease and tumors of the small intestine and large bowel
    • Bozkurt T, Richter F, Lux G. Ultrasonography as a primary diagnostic tool in patients with inflammatory disease and tumors of the small intestine and large bowel. J. Clin. Ultrasound 22(2), 85-91 (1994).
    • (1994) J. Clin. Ultrasound , vol.22 , Issue.2 , pp. 85-91
    • Bozkurt, T.1    Richter, F.2    Lux, G.3
  • 23
    • 20744442557 scopus 로고    scopus 로고
    • Role of US in detection of Crohn disease: Meta-analysis
    • Fraquelli M, Colli A, Casazza G et al. Role of US in detection of Crohn disease: meta-analysis. Radiology 236(1), 95-101 (2005).
    • (2005) Radiology , vol.236 , Issue.1 , pp. 95-101
    • Fraquelli, M.1    Colli, A.2    Casazza, G.3
  • 24
    • 66649100476 scopus 로고    scopus 로고
    • Monitoring disease activity by stool analyses: From occult blood to molecular markers of intestinal inflammation and damage
    • Foell D, Wittkowski H, Roth J. Monitoring disease activity by stool analyses: from occult blood to molecular markers of intestinal inflammation and damage. Gut 58(6), 859-868 (2009).
    • (2009) Gut , vol.58 , Issue.6 , pp. 859-868
    • Foell, D.1    Wittkowski, H.2    Roth, J.3
  • 25
    • 0029886064 scopus 로고    scopus 로고
    • Fecal lactoferrin as a marker for disease activity in inflammatory bowel disease: Comparison with other neutrophil-derived proteins
    • Sugi K, Saitoh O, Hirata I, Katsu K. Fecal lactoferrin as a marker for disease activity in inflammatory bowel disease: comparison with other neutrophil-derived proteins. Am. J. Gastroenterol. 91(5), 927-934 (1996).
    • (1996) Am. J. Gastroenterol , vol.91 , Issue.5 , pp. 927-934
    • Sugi, K.1    Saitoh, O.2    Hirata, I.3    Katsu, K.4
  • 26
    • 0033013167 scopus 로고    scopus 로고
    • Correlation between faecal excretion of indium-111-labelled granulocytes and calprotectin, a granulocyte marker protein, in patients with inflammatory bowel disease
    • Roseth AG, Schmidt PN, Fagerhol MK. Correlation between faecal excretion of indium-111-labelled granulocytes and calprotectin, a granulocyte marker protein, in patients with inflammatory bowel disease. Scand. J. Gastroenterol. 34(1), 50-54 (1999).
    • (1999) Scand. J. Gastroenterol , vol.34 , Issue.1 , pp. 50-54
    • Roseth, A.G.1    Schmidt, P.N.2    Fagerhol, M.K.3
  • 27
    • 1542394043 scopus 로고    scopus 로고
    • Role of faecal calprotectin as non-invasive marker of intestinal inflammation
    • Costa F, Mumolo MG, Bellini M et al. Role of faecal calprotectin as non-invasive marker of intestinal inflammation. Dig. Liver Dis. 35(9), 642-647 (2003).
    • (2003) Dig. Liver Dis , vol.35 , Issue.9 , pp. 642-647
    • Costa, F.1    Mumolo, M.G.2    Bellini, M.3
  • 28
    • 57449085396 scopus 로고    scopus 로고
    • Questions and answers on the role of faecal calprotectin as a biological marker in inflammatory bowel disease
    • Gisbert JP, McNicholl AG. Questions and answers on the role of faecal calprotectin as a biological marker in inflammatory bowel disease. Dig. Liver Dis. 41(1), 56-66 (2009).
    • (2009) Dig. Liver Dis , vol.41 , Issue.1 , pp. 56-66
    • Gisbert, J.P.1    McNicholl, A.G.2
  • 29
    • 4644303010 scopus 로고    scopus 로고
    • Relationship between fecal calprotectin, intestinal inflammation, and peripheral blood neutrophils in patients with active ulcerative colitis
    • Hanai H, Takeuchi K, Iida T et al. Relationship between fecal calprotectin, intestinal inflammation, and peripheral blood neutrophils in patients with active ulcerative colitis. Dig. Dis. Sci. 49(9), 1438-1443 (2004).
    • (2004) Dig. Dis. Sci , vol.49 , Issue.9 , pp. 1438-1443
    • Hanai, H.1    Takeuchi, K.2    Iida, T.3
  • 30
    • 55149092209 scopus 로고    scopus 로고
    • Relationships between disease activity and serum and fecal biomarkers in patients with Crohn's disease
    • Jones J, Loftus EV Jr, Panaccione R et al. Relationships between disease activity and serum and fecal biomarkers in patients with Crohn's disease. Clin. Gastroenterol. Hepatol. 6(11), 1218-1224 (2008).
    • (2008) Clin. Gastroenterol. Hepatol , vol.6 , Issue.11 , pp. 1218-1224
    • Jones, J.1    Loftus Jr., E.V.2    Panaccione, R.3
  • 31
    • 6344246551 scopus 로고    scopus 로고
    • Normalization of faecal calprotectin: A predictor of mucosal healing in patients with inflammatory bowel disease
    • Roseth AG, Aadland E, Grzyb K. Normalization of faecal calprotectin: a predictor of mucosal healing in patients with inflammatory bowel disease. Scand. J. Gastroenterol. 39(10), 1017-1020 (2004).
    • (2004) Scand. J. Gastroenterol , vol.39 , Issue.10 , pp. 1017-1020
    • Roseth, A.G.1    Aadland, E.2    Grzyb, K.3
  • 32
    • 54049150524 scopus 로고    scopus 로고
    • Fecal calprotectin, lactoferrin, and endoscopic disease activity in monitoring anti-TNF-A therapy for Crohn's disease
    • Sipponen T, Savilahti E, Karkkainen P et al. Fecal calprotectin, lactoferrin, and endoscopic disease activity in monitoring anti-TNF-a therapy for Crohn's disease. Inflamm. Bowel Dis. 14(10), 1392-1398 (2008).
    • (2008) Inflamm. Bowel Dis , vol.14 , Issue.10 , pp. 1392-1398
    • Sipponen, T.1    Savilahti, E.2    Karkkainen, P.3
  • 33
    • 61949096973 scopus 로고    scopus 로고
    • Fecal calprotectin predicts the clinical course of acute severe ulcerative colitis
    • Ho GT, Lee HM, Brydon G et al. Fecal calprotectin predicts the clinical course of acute severe ulcerative colitis. Am. J. Gastroenterol. 104(3), 673-678 (2009).
    • (2009) Am. J. Gastroenterol , vol.104 , Issue.3 , pp. 673-678
    • Ho, G.T.1    Lee, H.M.2    Brydon, G.3
  • 34
    • 70349484242 scopus 로고    scopus 로고
    • Fecal calprotectin and lactoferrin for the prediction of inflammatory bowel disease relapse
    • Gisbert JP, Bermejo F, Perez-Calle JL et al. Fecal calprotectin and lactoferrin for the prediction of inflammatory bowel disease relapse. Inflamm. Bowel Dis. 15(8), 1190-1198 (2009).
    • (2009) Inflamm. Bowel Dis , vol.15 , Issue.8 , pp. 1190-1198
    • Gisbert, J.P.1    Bermejo, F.2    Perez-Calle, J.L.3
  • 35
    • 70350653920 scopus 로고    scopus 로고
    • Questions and answers on the role of fecal lactoferrin as a biological marker in inflammatory bowel disease
    • Gisbert JP, McNicholl AG, Gomollon F. Questions and answers on the role of fecal lactoferrin as a biological marker in inflammatory bowel disease. Inflamm. Bowel Dis. 15(11), 1746-1754 (2009).
    • (2009) Inflamm. Bowel Dis , vol.15 , Issue.11 , pp. 1746-1754
    • Gisbert, J.P.1    McNicholl, A.G.2    Gomollon, F.3
  • 36
    • 49349114912 scopus 로고    scopus 로고
    • Can calprotectin predict relapse risk in inflammatory bowel disease?
    • D'Inca R, Dal Pont E, Di Leo V et al. Can calprotectin predict relapse risk in inflammatory bowel disease? Am. J. Gastroenterol. 103(8), 2007-2014 (2008).
    • (2008) Am J. Gastroenterol , vol.103 , Issue.8 , pp. 2007-2014
    • D'inca, R.1    Dal Pont, E.2    Di Leo, V.3
  • 37
    • 84876457416 scopus 로고    scopus 로고
    • Low-dose maintenance therapy with infliximab prevents postsurgical recurrence of Crohn's disease
    • DOI: 10.1016/j.cgh.2010.01.016, Epub ahead of print
    • Sorrentino D, Paviotti A, Terrosu G, Avellini C, Geraci M, Zarifi D. Low-dose maintenance therapy with infliximab prevents postsurgical recurrence of Crohn's disease. Clin. Gastroenterol. Hepatol. DOI: 10.1016/j.cgh.2010.01.016 (2010) (Epub ahead of print).
    • (2010) Clin. Gastroenterol. Hepatol.
    • Sorrentino, D.1    Paviotti, A.2    Terrosu, G.3    Avellini, C.4    Geraci, M.5    Zarifi, D.6
  • 38
    • 33745714449 scopus 로고    scopus 로고
    • Fecal calprotectin remains high during glucocorticoid therapy in children with inflammatory bowel disease
    • Kolho KL, Raivio T, Lindahl H, Savilahti E. Fecal calprotectin remains high during glucocorticoid therapy in children with inflammatory bowel disease. Scand. J. Gastroenterol. 41(6), 720-725 (2006).
    • (2006) Scand. J. Gastroenterol , vol.41 , Issue.6 , pp. 720-725
    • Kolho, K.L.1    Raivio, T.2    Lindahl, H.3    Savilahti, E.4
  • 39
    • 0022976949 scopus 로고
    • Monocyte-conditioned medium, interleukin-1, and tumor necrosis factor stimulate the acute phase response in human hepatoma cells in vitro
    • Darlington GJ, Wilson DR, Lachman LB. Monocyte-conditioned medium, interleukin-1, and tumor necrosis factor stimulate the acute phase response in human hepatoma cells in vitro. J. Cell Biol. 103(3), 787-793 (1986).
    • (1986) J. Cell Biol , vol.103 , Issue.3 , pp. 787-793
    • Darlington, G.J.1    Wilson, D.R.2    Lachman, L.B.3
  • 40
    • 37849053698 scopus 로고    scopus 로고
    • Noninvasive markers in the assessment of intestinal inflammation in inflammatory bowel diseases: Performance of fecal lactoferrin, calprotectin, and PMN-elastase, CRP, and clinical indices
    • Langhorst J, Elsenbruch S, Koelzer J, Rueffer A, Michalsen A, Dobos GJ. Noninvasive markers in the assessment of intestinal inflammation in inflammatory bowel diseases: performance of fecal lactoferrin, calprotectin, and PMN-elastase, CRP, and clinical indices. Am. J. Gastroenterol. 103(1), 162-169 (2008).
    • (2008) Am. J. Gastroenterol , vol.103 , Issue.1 , pp. 162-169
    • Langhorst, J.1    Elsenbruch, S.2    Koelzer, J.3    Rueffer, A.4    Michalsen, A.5    Dobos, G.J.6
  • 41
    • 34547843598 scopus 로고    scopus 로고
    • CRP correlates with clinical score in ulcerative colitis but not in Crohn's disease
    • Rodgers AD, Cummins AG. CRP correlates with clinical score in ulcerative colitis but not in Crohn's disease. Dig. Dis. Sci. 52(9), 2063-2068 (2007).
    • (2007) Dig. Dis. Sci , vol.52 , Issue.9 , pp. 2063-2068
    • Rodgers, A.D.1    Cummins, A.G.2
  • 42
    • 10744231062 scopus 로고    scopus 로고
    • Human CRP gene polymorphism influences CRP levels: Implications for the prediction and pathogenesis of coronary heart disease
    • Brull DJ, Serrano N, Zito F et al. Human CRP gene polymorphism influences CRP levels: implications for the prediction and pathogenesis of coronary heart disease. Arterioscler. Thromb. Vasc. Biol. 23(11), 2063-2069 (2003).
    • (2003) Arterioscler. Thromb. Vasc. Biol , vol.23 , Issue.11 , pp. 2063-2069
    • Brull, D.J.1    Serrano, N.2    Zito, F.3
  • 43
    • 0012205654 scopus 로고    scopus 로고
    • Cytokine gene polymorphism in human disease: On-line databases, supplement 2
    • Haukim N, Bidwell JL, Smith AJ et al. Cytokine gene polymorphism in human disease: on-line databases, supplement 2. Genes Immun. 3(6), 313-330 (2002).
    • (2002) Genes Immun , vol.3 , Issue.6 , pp. 313-330
    • Haukim, N.1    Bidwell, J.L.2    Smith, A.J.3
  • 44
    • 24644474678 scopus 로고    scopus 로고
    • Correlation of C-reactive protein with clinical, endoscopic, histologic, and radiographic activity in inflammatory bowel disease
    • Solem CA, Loftus EV Jr, Tremaine WJ, Harmsen WS, Zinsmeister AR, Sandborn WJ. Correlation of C-reactive protein with clinical, endoscopic, histologic, and radiographic activity in inflammatory bowel disease. Inflamm. Bowel Dis. 11(8), 707-712 (2005).
    • (2005) Inflamm. Bowel Dis , vol.11 , Issue.8 , pp. 707-712
    • Solem, C.A.1    Loftus Jr., E.V.2    Tremaine, W.J.3    Harmsen, W.S.4    Zinsmeister, A.R.5    Sandborn, W.J.6
  • 45
    • 34548642850 scopus 로고    scopus 로고
    • Assessment of endoscopic activity index and biological inflammatory markers in clinically active Crohn's disease with normal C-reactive protein serum level
    • Denis MA, Reenaers C, Fontaine F, Belaiche J, Louis E. Assessment of endoscopic activity index and biological inflammatory markers in clinically active Crohn's disease with normal C-reactive protein serum level. Inflamm. Bowel Dis. 13(9), 1100-1105 (2007).
    • (2007) Inflamm. Bowel Dis , vol.13 , Issue.9 , pp. 1100-1105
    • Denis, M.A.1    Reenaers, C.2    Fontaine, F.3    Belaiche, J.4    Louis, E.5
  • 46
    • 0023713590 scopus 로고
    • The clinical significance of serum C reactive protein levels in Crohn's disease. Results of a prospective longitudinal study
    • Boirivant M, Leoni M, Tariciotti D, Fais S, Squarcia O, Pallone F. The clinical significance of serum C reactive protein levels in Crohn's disease. Results of a prospective longitudinal study. J. Clin. Gastroenterol. 10(4), 401-405 (1988).
    • (1988) J. Clin. Gastroenterol , vol.10 , Issue.4 , pp. 401-405
    • Boirivant, M.1    Leoni, M.2    Tariciotti, D.3    Fais, S.4    Squarcia, O.5    Pallone, F.6
  • 48
    • 63849101007 scopus 로고    scopus 로고
    • Long-term outcome of treatment with infliximab in 614 patients with Crohn's disease: Results from a single-centre cohort
    • Schnitzler F, Fidder H, Ferrante M et al. Long-term outcome of treatment with infliximab in 614 patients with Crohn's disease: results from a single-centre cohort. Gut 58(4), 492-500 (2009).
    • (2009) Gut , vol.58 , Issue.4 , pp. 492-500
    • Schnitzler, F.1    Fidder, H.2    Ferrante, M.3
  • 49
    • 33847664069 scopus 로고    scopus 로고
    • Anti-flagellin (CBir1) phenotypic and genetic Crohn's disease associations
    • Papadakis KA, Yang H, Ippoliti A et al. Anti-flagellin (CBir1) phenotypic and genetic Crohn's disease associations. Inflamm. Bowel Dis. 13(5), 524-530 (2007).
    • (2007) Inflamm. Bowel Dis , vol.13 , Issue.5 , pp. 524-530
    • Papadakis, K.A.1    Yang, H.2    Ippoliti, A.3
  • 50
    • 34548153548 scopus 로고    scopus 로고
    • Seroreactivity to microbial components in Crohn's disease is associated with ileal involvement, noninflammatory disease behavior and NOD2/CARD15 genotype, but not with risk for surgery in a Hungarian cohort of IBD patients
    • Papp M, Altorjay I, Norman GL et al. Seroreactivity to microbial components in Crohn's disease is associated with ileal involvement, noninflammatory disease behavior and NOD2/CARD15 genotype, but not with risk for surgery in a Hungarian cohort of IBD patients. Inflamm. Bowel Dis. 13(8), 984-992 (2007).
    • (2007) Inflamm. Bowel Dis , vol.13 , Issue.8 , pp. 984-992
    • Papp, M.1    Altorjay, I.2    Norman, G.L.3
  • 51
    • 33751557468 scopus 로고    scopus 로고
    • Antibodies to I2 predict clinical response to fecal diversion in Crohn's disease
    • Spivak J, Landers CJ, Vasiliauskas EA et al. Antibodies to I2 predict clinical response to fecal diversion in Crohn's disease. Inflamm. Bowel Dis. 12(12), 1122-1130 (2006).
    • (2006) Inflamm. Bowel Dis , vol.12 , Issue.12 , pp. 1122-1130
    • Spivak, J.1    Landers, C.J.2    Vasiliauskas, E.A.3
  • 52
    • 41149103489 scopus 로고    scopus 로고
    • Autoantibodies against ubiquitination factor E4A (UBE4A) are associated with severity of Crohn's disease
    • Sakiyama T, Fujita H, Tsubouchi H. Autoantibodies against ubiquitination factor E4A (UBE4A) are associated with severity of Crohn's disease. Inflamm. Bowel Dis. 14(3), 310-317 (2008).
    • (2008) Inflamm. Bowel Dis , vol.14 , Issue.3 , pp. 310-317
    • Sakiyama, T.1    Fujita, H.2    Tsubouchi, H.3
  • 53
    • 34548131585 scopus 로고    scopus 로고
    • The immune response in inflammatory bowel disease
    • Brown SJ, Mayer L. The immune response in inflammatory bowel disease. Am. J. Gastroenterol. 102(9), 2058-2069 (2007).
    • (2007) Am. J. Gastroenterol , vol.102 , Issue.9 , pp. 2058-2069
    • Brown, S.J.1    Mayer, L.2
  • 54
    • 43349107173 scopus 로고    scopus 로고
    • Novel therapeutic targets in the treatment of IBD
    • Kaser A, Tilg H. Novel therapeutic targets in the treatment of IBD. Expert Opin. Ther. Targets 12(5), 553-563 (2008).
    • (2008) Expert Opin. Ther. Targets , vol.12 , Issue.5 , pp. 553-563
    • Kaser, A.1    Tilg, H.2
  • 55
    • 0031873103 scopus 로고    scopus 로고
    • Cytokines in inflammatory bowel disease
    • Kmiec Z. Cytokines in inflammatory bowel disease. Arch. Immunol. Ther. Exp. (Warsz.) 46(3), 143-155 (1998).
    • (1998) Arch. Immunol. Ther. Exp. (Warsz.) , vol.46 , Issue.3 , pp. 143-155
    • Kmiec, Z.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.