메뉴 건너뛰기




Volumn 425, Issue 4, 2013, Pages 697-712

Intrinsic translocation barrier as an initial step in pausing by RNA polymerase II

Author keywords

backtracking; pausing; RNA polymerase II; transcription elongation; translocation

Indexed keywords

ELONGATION FACTOR; RNA POLYMERASE II;

EID: 84873408886     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2012.12.002     Document Type: Article
Times cited : (37)

References (61)
  • 2
    • 70350783881 scopus 로고    scopus 로고
    • Tracking rates of transcription and splicing in vivo
    • M.B. Ardehali, and J.T. Lis Tracking rates of transcription and splicing in vivo Nat. Struct. Mol. Biol. 16 2009 1123 1124
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , pp. 1123-1124
    • Ardehali, M.B.1    Lis, J.T.2
  • 4
    • 0032478549 scopus 로고    scopus 로고
    • RNA polymerase as a molecular motor
    • J. Gelles, and R. Landick RNA polymerase as a molecular motor Cell 93 1998 13 16
    • (1998) Cell , vol.93 , pp. 13-16
    • Gelles, J.1    Landick, R.2
  • 5
    • 0031008221 scopus 로고    scopus 로고
    • Basic mechanisms of transcript elongation and its regulation
    • S.M. Uptain, C.M. Kane, and M.J. Chamberlin Basic mechanisms of transcript elongation and its regulation Annu. Rev. Biochem. 66 1997 117 172
    • (1997) Annu. Rev. Biochem. , vol.66 , pp. 117-172
    • Uptain, S.M.1    Kane, C.M.2    Chamberlin, M.J.3
  • 6
    • 7444253928 scopus 로고    scopus 로고
    • Sequence-dependent kinetic model for transcription elongation by RNA polymerase
    • L. Bai, A. Shundrovsky, and M.D. Wang Sequence-dependent kinetic model for transcription elongation by RNA polymerase J. Mol. Biol. 344 2004 335 349
    • (2004) J. Mol. Biol. , vol.344 , pp. 335-349
    • Bai, L.1    Shundrovsky, A.2    Wang, M.D.3
  • 7
    • 0142127778 scopus 로고    scopus 로고
    • Motion of RNA polymerase along DNA: A stochastic model
    • F. Julicher, and R. Bruinsma Motion of RNA polymerase along DNA: a stochastic model Biophys. J. 74 1998 1169 1185
    • (1998) Biophys. J. , vol.74 , pp. 1169-1185
    • Julicher, F.1    Bruinsma, R.2
  • 8
    • 34147206187 scopus 로고    scopus 로고
    • Backtracking determines the force sensitivity of RNAP II in a factor-dependent manner
    • E.A. Galburt, S.W. Grill, A. Wiedmann, L. Lubkowska, J. Choy, and E. Nogales Backtracking determines the force sensitivity of RNAP II in a factor-dependent manner Nature 446 2007 820 823
    • (2007) Nature , vol.446 , pp. 820-823
    • Galburt, E.A.1    Grill, S.W.2    Wiedmann, A.3    Lubkowska, L.4    Choy, J.5    Nogales, E.6
  • 9
    • 0346258014 scopus 로고    scopus 로고
    • Backtracking by single RNA polymerase molecules observed at near-base-pair resolution
    • J.W. Shaevitz, E.A. Abbondanzieri, R. Landick, and S.M. Block Backtracking by single RNA polymerase molecules observed at near-base-pair resolution Nature 426 2003 684 687
    • (2003) Nature , vol.426 , pp. 684-687
    • Shaevitz, J.W.1    Abbondanzieri, E.A.2    Landick, R.3    Block, S.M.4
  • 10
    • 0031059249 scopus 로고    scopus 로고
    • Transcriptional arrest: Escherichia coli RNA polymerase translocates backward, leaving the 3′ end of the RNA intact and extruded
    • N. Komissarova, and M. Kashlev Transcriptional arrest: Escherichia coli RNA polymerase translocates backward, leaving the 3′ end of the RNA intact and extruded Proc. Natl Acad. Sci. USA 94 1997 1755 1760
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 1755-1760
    • Komissarova, N.1    Kashlev, M.2
  • 11
    • 0035838977 scopus 로고    scopus 로고
    • Roles of RNA:DNA hybrid stability, RNA structure, and active site conformation in pausing by human RNA polymerase II
    • M. Palangat, and R. Landick Roles of RNA:DNA hybrid stability, RNA structure, and active site conformation in pausing by human RNA polymerase II J. Mol. Biol. 311 2001 265 282
    • (2001) J. Mol. Biol. , vol.311 , pp. 265-282
    • Palangat, M.1    Landick, R.2
  • 12
    • 66349138227 scopus 로고    scopus 로고
    • Structural basis of transcription: Backtracked RNA polymerase II at 3.4 angstrom resolution
    • D. Wang, D.A. Bushnell, X. Huang, K.D. Westover, M. Levitt, and R.D. Kornberg Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution Science 324 2009 1203 1206
    • (2009) Science , vol.324 , pp. 1203-1206
    • Wang, D.1    Bushnell, D.A.2    Huang, X.3    Westover, K.D.4    Levitt, M.5    Kornberg, R.D.6
  • 13
    • 0033179498 scopus 로고    scopus 로고
    • Transcriptional pause, arrest and termination sites for RNA polymerase II in mammalian N- and c-myc genes
    • R.G. Keene, A. Mueller, R. Landick, and L. London Transcriptional pause, arrest and termination sites for RNA polymerase II in mammalian N- and c-myc genes Nucleic Acids Res. 27 1999 3173 3182
    • (1999) Nucleic Acids Res. , vol.27 , pp. 3173-3182
    • Keene, R.G.1    Mueller, A.2    Landick, R.3    London, L.4
  • 14
    • 0030987775 scopus 로고    scopus 로고
    • Transcription elongation through DNA arrest sites. A multistep process involving both RNA polymerase II subunit RPB9 and TFIIS
    • D.E. Awrey, R.G. Weilbaecher, S.A. Hemming, S.M. Orlicky, C.M. Kane, and A.M. Edwards Transcription elongation through DNA arrest sites. A multistep process involving both RNA polymerase II subunit RPB9 and TFIIS J. Biol. Chem. 272 1997 14747 14754
    • (1997) J. Biol. Chem. , vol.272 , pp. 14747-14754
    • Awrey, D.E.1    Weilbaecher, R.G.2    Hemming, S.A.3    Orlicky, S.M.4    Kane, C.M.5    Edwards, A.M.6
  • 15
    • 0027536870 scopus 로고
    • Transcript cleavage factors from E. coli
    • S. Borukhov, V. Sagitov, and A. Goldfarb Transcript cleavage factors from E. coli Cell 72 1993 459 466
    • (1993) Cell , vol.72 , pp. 459-466
    • Borukhov, S.1    Sagitov, V.2    Goldfarb, A.3
  • 16
    • 0026648570 scopus 로고
    • The RNA polymerase II ternary complex cleaves the nascent transcript in a 3′-5′ direction in the presence of elongation factor SII
    • M.G. Izban, and D.S. Luse The RNA polymerase II ternary complex cleaves the nascent transcript in a 3′-5′ direction in the presence of elongation factor SII Genes Dev. 6 1992 1342 1356
    • (1992) Genes Dev. , vol.6 , pp. 1342-1356
    • Izban, M.G.1    Luse, D.S.2
  • 17
    • 0026647901 scopus 로고
    • The RNA polymerase II elongation complex. Factor-dependent transcription elongation involves nascent RNA cleavage
    • D. Reines, P. Ghanouni, Q.Q. Li, and J. Mote Jr The RNA polymerase II elongation complex. Factor-dependent transcription elongation involves nascent RNA cleavage J. Biol. Chem. 267 1992 15516 15522
    • (1992) J. Biol. Chem. , vol.267 , pp. 15516-15522
    • Reines, D.1    Ghanouni, P.2    Li, Q.Q.3    Mote, Jr.J.4
  • 18
    • 0030950638 scopus 로고    scopus 로고
    • RNA polymerase switches between inactivated and activated states by translocating back and forth along the DNA and the RNA
    • N. Komissarova, and M. Kashlev RNA polymerase switches between inactivated and activated states by translocating back and forth along the DNA and the RNA J. Biol. Chem. 272 1997 15329 15338
    • (1997) J. Biol. Chem. , vol.272 , pp. 15329-15338
    • Komissarova, N.1    Kashlev, M.2
  • 19
    • 0043244876 scopus 로고    scopus 로고
    • Architecture of the RNA polymerase II-TFIIS complex and implications for mRNA cleavage
    • H. Kettenberger, K.J. Armache, and P. Cramer Architecture of the RNA polymerase II-TFIIS complex and implications for mRNA cleavage Cell 114 2003 347 357
    • (2003) Cell , vol.114 , pp. 347-357
    • Kettenberger, H.1    Armache, K.J.2    Cramer, P.3
  • 20
    • 77950998789 scopus 로고    scopus 로고
    • Evidence that transcript cleavage is essential for RNA polymerase II transcription and cell viability
    • S. Sigurdsson, A.B. Dirac-Svejstrup, and J.Q. Svejstrup Evidence that transcript cleavage is essential for RNA polymerase II transcription and cell viability Mol. Cell 38 2010 202 210
    • (2010) Mol. Cell , vol.38 , pp. 202-210
    • Sigurdsson, S.1    Dirac-Svejstrup, A.B.2    Svejstrup, J.Q.3
  • 21
    • 10944232674 scopus 로고    scopus 로고
    • Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS
    • H. Kettenberger, K.J. Armache, and P. Cramer Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS Mol. Cell 16 2004 955 965
    • (2004) Mol. Cell , vol.16 , pp. 955-965
    • Kettenberger, H.1    Armache, K.J.2    Cramer, P.3
  • 22
    • 79952440464 scopus 로고    scopus 로고
    • Structural basis of RNA polymerase II backtracking, arrest and reactivation
    • A.C. Cheung, and P. Cramer Structural basis of RNA polymerase II backtracking, arrest and reactivation Nature 471 2011 249 253
    • (2011) Nature , vol.471 , pp. 249-253
    • Cheung, A.C.1    Cramer, P.2
  • 23
    • 44449094019 scopus 로고    scopus 로고
    • Transient reversal of RNA polymerase II active site closing controls fidelity of transcription elongation
    • M.L. Kireeva, Y.A. Nedialkov, G.H. Cremona, Y.A. Purtov, L. Lubkowska, and F. Malagon Transient reversal of RNA polymerase II active site closing controls fidelity of transcription elongation Mol. Cell 30 2008 557 566
    • (2008) Mol. Cell , vol.30 , pp. 557-566
    • Kireeva, M.L.1    Nedialkov, Y.A.2    Cremona, G.H.3    Purtov, Y.A.4    Lubkowska, L.5    Malagon, F.6
  • 24
    • 33751235874 scopus 로고    scopus 로고
    • Structural basis of transcription: Role of the trigger loop in substrate specificity and catalysis
    • D. Wang, D.A. Bushnell, K.D. Westover, C.D. Kaplan, and R.D. Kornberg Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis Cell 127 2006 941 954
    • (2006) Cell , vol.127 , pp. 941-954
    • Wang, D.1    Bushnell, D.A.2    Westover, K.D.3    Kaplan, C.D.4    Kornberg, R.D.5
  • 27
    • 67849124180 scopus 로고    scopus 로고
    • Millisecond phase kinetic analysis of elongation catalyzed by human, yeast, and Escherichia coli RNA polymerase
    • M. Kireeva, Y.A. Nedialkov, X.Q. Gong, C. Zhang, Y. Xiong, and W. Moon Millisecond phase kinetic analysis of elongation catalyzed by human, yeast, and Escherichia coli RNA polymerase Methods 48 2009 333 345
    • (2009) Methods , vol.48 , pp. 333-345
    • Kireeva, M.1    Nedialkov, Y.A.2    Gong, X.Q.3    Zhang, C.4    Xiong, Y.5    Moon, W.6
  • 28
    • 0345047725 scopus 로고    scopus 로고
    • Ubiquitous transcriptional pausing is independent of RNA polymerase backtracking
    • K.C. Neuman, E.A. Abbondanzieri, R. Landick, J. Gelles, and S.M. Block Ubiquitous transcriptional pausing is independent of RNA polymerase backtracking Cell 115 2003 437 447
    • (2003) Cell , vol.115 , pp. 437-447
    • Neuman, K.C.1    Abbondanzieri, E.A.2    Landick, R.3    Gelles, J.4    Block, S.M.5
  • 30
    • 0142147268 scopus 로고    scopus 로고
    • A new class of bacterial RNA polymerase inhibitor affects nucleotide addition
    • I. Artsimovitch, C. Chu, A.S. Lynch, and R. Landick A new class of bacterial RNA polymerase inhibitor affects nucleotide addition Science 302 2003 650 654
    • (2003) Science , vol.302 , pp. 650-654
    • Artsimovitch, I.1    Chu, C.2    Lynch, A.S.3    Landick, R.4
  • 31
    • 84859710196 scopus 로고    scopus 로고
    • Mechanism of translesion transcription by RNA polymerase II and its role in cellular resistance to DNA damage
    • C. Walmacq, A.C. Cheung, M.L. Kireeva, L. Lubkowska, C. Ye, and D. Gotte Mechanism of translesion transcription by RNA polymerase II and its role in cellular resistance to DNA damage Mol. Cell 46 2012 1 12
    • (2012) Mol. Cell , vol.46 , pp. 1-12
    • Walmacq, C.1    Cheung, A.C.2    Kireeva, M.L.3    Lubkowska, L.4    Ye, C.5    Gotte, D.6
  • 32
    • 80052255345 scopus 로고    scopus 로고
    • Interaction of RNA polymerase II fork loop 2 with downstream non-template DNA regulates transcription elongation
    • M.L. Kireeva, C. Domecq, B. Coulombe, Z.F. Burton, and M. Kashlev Interaction of RNA polymerase II fork loop 2 with downstream non-template DNA regulates transcription elongation J. Biol. Chem. 286 2011 30898 30910
    • (2011) J. Biol. Chem. , vol.286 , pp. 30898-30910
    • Kireeva, M.L.1    Domecq, C.2    Coulombe, B.3    Burton, Z.F.4    Kashlev, M.5
  • 33
    • 0036863659 scopus 로고    scopus 로고
    • Shortening of RNA:DNA hybrid in the elongation complex of RNA polymerase is a prerequisite for transcription termination
    • N. Komissarova, J. Becker, S. Solter, M. Kireeva, and M. Kashlev Shortening of RNA:DNA hybrid in the elongation complex of RNA polymerase is a prerequisite for transcription termination Mol. Cell 10 2002 1151 1162
    • (2002) Mol. Cell , vol.10 , pp. 1151-1162
    • Komissarova, N.1    Becker, J.2    Solter, S.3    Kireeva, M.4    Kashlev, M.5
  • 34
    • 48749102174 scopus 로고    scopus 로고
    • Rapid kinetic analysis of transcription elongation by Escherichia coli RNA polymerase
    • R.S. Johnson, M. Strausbauch, R. Cooper, and J.K. Register Rapid kinetic analysis of transcription elongation by Escherichia coli RNA polymerase J. Mol. Biol. 381 2008 1106 1113
    • (2008) J. Mol. Biol. , vol.381 , pp. 1106-1113
    • Johnson, R.S.1    Strausbauch, M.2    Cooper, R.3    Register, J.K.4
  • 35
    • 33748571487 scopus 로고    scopus 로고
    • Elongation complexes of Thermus thermophilus RNA polymerase that possess distinct translocation conformations
    • E. Kashkina, M. Anikin, T.H. Tahirov, S.N. Kochetkov, D.G. Vassylyev, and D. Temiakov Elongation complexes of Thermus thermophilus RNA polymerase that possess distinct translocation conformations Nucleic Acids Res. 34 2006 4036 4045
    • (2006) Nucleic Acids Res. , vol.34 , pp. 4036-4045
    • Kashkina, E.1    Anikin, M.2    Tahirov, T.H.3    Kochetkov, S.N.4    Vassylyev, D.G.5    Temiakov, D.6
  • 36
    • 44449103640 scopus 로고    scopus 로고
    • The RNA polymerase II trigger loop functions in substrate selection and is directly targeted by alpha-amanitin
    • C.D. Kaplan, K.M. Larsson, and R.D. Kornberg The RNA polymerase II trigger loop functions in substrate selection and is directly targeted by alpha-amanitin Mol. Cell 30 2008 547 556
    • (2008) Mol. Cell , vol.30 , pp. 547-556
    • Kaplan, C.D.1    Larsson, K.M.2    Kornberg, R.D.3
  • 37
    • 0021723295 scopus 로고
    • Saccharomyces cerevisiae GAL1-GAL10 divergent promoter region: Location and function of the upstream activating sequence UASG
    • R.W. West Jr, R.R. Yocum, and M. Ptashne Saccharomyces cerevisiae GAL1-GAL10 divergent promoter region: location and function of the upstream activating sequence UASG Mol. Cell. Biol. 4 1984 2467 2478
    • (1984) Mol. Cell. Biol. , vol.4 , pp. 2467-2478
    • West, Jr.R.W.1    Yocum, R.R.2    Ptashne, M.3
  • 38
    • 15644377282 scopus 로고    scopus 로고
    • Yeast transcript elongation factor (TFIIS), structure and function. II: RNA polymerase binding, transcript cleavage, and read-through
    • D.E. Awrey, N. Shimasaki, C. Koth, R. Weilbaecher, V. Olmsted, and S. Kazanis Yeast transcript elongation factor (TFIIS), structure and function. II: RNA polymerase binding, transcript cleavage, and read-through J. Biol. Chem. 273 1998 22595 22605
    • (1998) J. Biol. Chem. , vol.273 , pp. 22595-22605
    • Awrey, D.E.1    Shimasaki, N.2    Koth, C.3    Weilbaecher, R.4    Olmsted, V.5    Kazanis, S.6
  • 39
    • 0025222740 scopus 로고
    • Protein motors and Maxwell's demons: Does mechanochemical transduction involve a thermal ratchet?
    • R.D. Vale, and F. Oosawa Protein motors and Maxwell's demons: does mechanochemical transduction involve a thermal ratchet? Adv. Biophys. 26 1990 97 134
    • (1990) Adv. Biophys. , vol.26 , pp. 97-134
    • Vale, R.D.1    Oosawa, F.2
  • 40
    • 80051538984 scopus 로고    scopus 로고
    • RNA transcript 3′-proximal sequence affects translocation bias of RNA polymerase
    • P.P. Hein, M. Palangat, and R. Landick RNA transcript 3′-proximal sequence affects translocation bias of RNA polymerase Biochemistry 50 2011 7002 7014
    • (2011) Biochemistry , vol.50 , pp. 7002-7014
    • Hein, P.P.1    Palangat, M.2    Landick, R.3
  • 41
    • 0026084789 scopus 로고
    • A thermodynamic analysis of RNA transcript elongation and termination in Escherichia coli
    • T.D. Yager, and P.H. von Hippel A thermodynamic analysis of RNA transcript elongation and termination in Escherichia coli Biochemistry 30 1991 1097 1118
    • (1991) Biochemistry , vol.30 , pp. 1097-1118
    • Yager, T.D.1    Von Hippel, P.H.2
  • 42
    • 33846914726 scopus 로고    scopus 로고
    • The regulatory roles and mechanism of transcriptional pausing
    • R. Landick The regulatory roles and mechanism of transcriptional pausing Biochem. Soc. Trans. 34 2006 1062 1066
    • (2006) Biochem. Soc. Trans. , vol.34 , pp. 1062-1066
    • Landick, R.1
  • 43
    • 0034691146 scopus 로고    scopus 로고
    • Pausing by bacterial RNA polymerase is mediated by mechanistically distinct classes of signals
    • I. Artsimovitch, and R. Landick Pausing by bacterial RNA polymerase is mediated by mechanistically distinct classes of signals Proc. Natl Acad. Sci. USA 97 2000 7090 7095
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 7090-7095
    • Artsimovitch, I.1    Landick, R.2
  • 44
    • 0032190641 scopus 로고    scopus 로고
    • Interaction of a nascent RNA structure with RNA polymerase is required for hairpin-dependent transcriptional pausing but not for transcript release
    • I. Artsimovitch, and R. Landick Interaction of a nascent RNA structure with RNA polymerase is required for hairpin-dependent transcriptional pausing but not for transcript release Genes Dev. 12 1998 3110 3122
    • (1998) Genes Dev. , vol.12 , pp. 3110-3122
    • Artsimovitch, I.1    Landick, R.2
  • 45
    • 34547204502 scopus 로고    scopus 로고
    • A central role of the RNA polymerase trigger loop in active-site rearrangement during transcriptional pausing
    • I. Toulokhonov, J. Zhang, M. Palangat, and R. Landick A central role of the RNA polymerase trigger loop in active-site rearrangement during transcriptional pausing Mol. Cell 27 2007 406 419
    • (2007) Mol. Cell , vol.27 , pp. 406-419
    • Toulokhonov, I.1    Zhang, J.2    Palangat, M.3    Landick, R.4
  • 46
    • 0034737593 scopus 로고    scopus 로고
    • Single-molecule study of transcriptional pausing and arrest by E. coli RNA polymerase
    • R.J. Davenport, G.J. Wuite, R. Landick, and C. Bustamante Single-molecule study of transcriptional pausing and arrest by E. coli RNA polymerase Science 287 2000 2497 2500
    • (2000) Science , vol.287 , pp. 2497-2500
    • Davenport, R.J.1    Wuite, G.J.2    Landick, R.3    Bustamante, C.4
  • 48
    • 0346243938 scopus 로고    scopus 로고
    • Transcript cleavage factors GreA and GreB act as transient catalytic components of RNA polymerase
    • O. Laptenko, J. Lee, I. Lomakin, and S. Borukhov Transcript cleavage factors GreA and GreB act as transient catalytic components of RNA polymerase EMBO J. 22 2003 6322 6334
    • (2003) EMBO J. , vol.22 , pp. 6322-6334
    • Laptenko, O.1    Lee, J.2    Lomakin, I.3    Borukhov, S.4
  • 49
    • 0035827332 scopus 로고    scopus 로고
    • Structural basis of transcription: An RNA polymerase II elongation complex at 3.3 Å resolution
    • A.L. Gnatt, P. Cramer, J. Fu, D.A. Bushnell, and R.D. Kornberg Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 Å resolution Science 292 2001 1876 1882
    • (2001) Science , vol.292 , pp. 1876-1882
    • Gnatt, A.L.1    Cramer, P.2    Fu, J.3    Bushnell, D.A.4    Kornberg, R.D.5
  • 50
    • 70450260475 scopus 로고    scopus 로고
    • Molecular basis of transcriptional mutagenesis at 8-oxoguanine
    • G.E. Damsma, and P. Cramer Molecular basis of transcriptional mutagenesis at 8-oxoguanine J. Biol. Chem. 284 2009 31658 31663
    • (2009) J. Biol. Chem. , vol.284 , pp. 31658-31663
    • Damsma, G.E.1    Cramer, P.2
  • 51
    • 67449116330 scopus 로고    scopus 로고
    • Structural basis of transcription: Mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA
    • J.F. Sydow, F. Brueckner, A.C. Cheung, G.E. Damsma, S. Dengl, and E. Lehmann Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA Mol. Cell 34 2009 710 721
    • (2009) Mol. Cell , vol.34 , pp. 710-721
    • Sydow, J.F.1    Brueckner, F.2    Cheung, A.C.3    Damsma, G.E.4    Dengl, S.5    Lehmann, E.6
  • 52
    • 0032113494 scopus 로고    scopus 로고
    • Crucial role of the RNA:DNA hybrid in the processivity of transcription
    • I. Sidorenkov, N. Komissarova, and M. Kashlev Crucial role of the RNA:DNA hybrid in the processivity of transcription Mol. Cell 2 1998 55 64
    • (1998) Mol. Cell , vol.2 , pp. 55-64
    • Sidorenkov, I.1    Komissarova, N.2    Kashlev, M.3
  • 53
    • 0034051171 scopus 로고    scopus 로고
    • The 8-nucleotide-long RNA:DNA hybrid is a primary stability determinant of the RNA polymerase II elongation complex
    • M.L. Kireeva, N. Komissarova, D.S. Waugh, and M. Kashlev The 8-nucleotide-long RNA:DNA hybrid is a primary stability determinant of the RNA polymerase II elongation complex J. Biol. Chem. 275 2000 6530 6536
    • (2000) J. Biol. Chem. , vol.275 , pp. 6530-6536
    • Kireeva, M.L.1    Komissarova, N.2    Waugh, D.S.3    Kashlev, M.4
  • 55
    • 45849138859 scopus 로고    scopus 로고
    • Recognition of the unique structure of DNA:RNA hybrids
    • N.N. Shaw, and D.P. Arya Recognition of the unique structure of DNA:RNA hybrids Biochimie 90 2008 1026 1039
    • (2008) Biochimie , vol.90 , pp. 1026-1039
    • Shaw, N.N.1    Arya, D.P.2
  • 56
    • 0344418719 scopus 로고    scopus 로고
    • In vivo evidence for back and forth oscillations of the transcription elongation complex
    • F. Toulme, M. Guerin, N. Robichon, M. Leng, and A.R. Rahmouni In vivo evidence for back and forth oscillations of the transcription elongation complex EMBO J. 18 1999 5052 5060
    • (1999) EMBO J. , vol.18 , pp. 5052-5060
    • Toulme, F.1    Guerin, M.2    Robichon, N.3    Leng, M.4    Rahmouni, A.R.5
  • 57
    • 78751659330 scopus 로고    scopus 로고
    • Nascent transcript sequencing visualizes transcription at nucleotide resolution
    • L.S. Churchman, and J.S. Weissman Nascent transcript sequencing visualizes transcription at nucleotide resolution Nature 469 2011 368 373
    • (2011) Nature , vol.469 , pp. 368-373
    • Churchman, L.S.1    Weissman, J.S.2
  • 60
    • 79960100503 scopus 로고    scopus 로고
    • The mechanism of nucleosome traversal by RNA polymerase II: Roles for template uncoiling and transcript elongation factors
    • D.S. Luse, and V.M. Studitsky The mechanism of nucleosome traversal by RNA polymerase II: roles for template uncoiling and transcript elongation factors RNA Biol. 8 2011 581 585
    • (2011) RNA Biol. , vol.8 , pp. 581-585
    • Luse, D.S.1    Studitsky, V.M.2
  • 61
    • 0346515712 scopus 로고    scopus 로고
    • Assays and affinity purification of biotinylated and nonbiotinylated forms of double-tagged core RNA polymerase II from Saccharomyces cerevisiae
    • M.L. Kireeva, L. Lubkowska, N. Komissarova, and M. Kashlev Assays and affinity purification of biotinylated and nonbiotinylated forms of double-tagged core RNA polymerase II from Saccharomyces cerevisiae Methods Enzymol. 370 2003 138 155
    • (2003) Methods Enzymol. , vol.370 , pp. 138-155
    • Kireeva, M.L.1    Lubkowska, L.2    Komissarova, N.3    Kashlev, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.