Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - New evidence on the antiinflammatory mode of action of bromelain

Phytotherapy Research

Volumn 27, Issue 2, 2013, Pages 199-204

  Müller, Silke ^a   März, Reinhard ^b   Schmolz, Manfred ^d   Drewelow, Bernd ^a   Eschmann, Klaus ^c   Meiser, Peter ^c  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b NUREMBERG INSTITUTE OF TECHNOLOGY   (Germany)

^c URSAPHARM Arzneimittel GmbH   (Germany)

^d EDI Experimental and Diagnostic Immunology GmbH   (Germany)

Author keywords

bromelain; clinical trial; cytokine; human; immune system; inflammation

Indexed keywords

BROMELAIN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 5; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; PLACEBO;

ABSENCE OF SIDE EFFECTS; ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG MECHANISM; DRUG MEGADOSE; DRUG TOLERABILITY; HUMAN; HUMAN EXPERIMENT; IMMUNE SYSTEM; IMMUNOMODULATION; LEUKOCYTE; LOW DRUG DOSE; MALE; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; T LYMPHOCYTE;

ADMINISTRATION, ORAL; ADULT; ANTI-INFLAMMATORY AGENTS; BROMELAINS; CELLS, CULTURED; CIRCADIAN RHYTHM; CROSS-OVER STUDIES; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-5; LYMPHOCYTES; MALE; YOUNG ADULT;

EID: 84873407187     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4678     Document Type: Article

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