Hyperforin attenuates brain damage induced by transient middle cerebral artery occlusion (MCAO) in rats via inhibition of TRPC6 channels degradation

Journal of Cerebral Blood Flow and Metabolism

Volumn 33, Issue 2, 2013, Pages 253-262

  Lin, Yun ^a   Zhang, Jian Cheng ^a   Fu, Jun ^b   Chen, Fang ^a   Wang, Jie ^a   Wu, Zhi Lin ^a   Yuan, Shi Ying ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HUBEI UNIVERSITY OF MEDICINE   (China)

Author keywords

acute stroke; animal models; calcium channels; focal ischemia; neuroprotection

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CALPAIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HYPERFORIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE; RAS PROTEIN; SPECTRIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; EARLY INTERVENTION; ENZYME ACTIVITY; ENZYME INHIBITION; IMMUNOFLUORESCENCE TEST; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL NECROSIS; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION INJURY; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 4; CALPAIN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MAP KINASE SIGNALING SYSTEM; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; PHLOROGLUCINOL; PHOSPHORYLATION; PROTEOLYSIS; RATS; RATS, SPRAGUE-DAWLEY; TERPENES; TRPC CATION CHANNELS;

EID: 84873405333     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2012.164     Document Type: Article

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