메뉴 건너뛰기




Volumn 7, Issue , 2013, Pages 37-52

Emerging treatment options for nasopharyngeal carcinoma

Author keywords

Chemoradiotherapy; Immunotherapy; Intensity modulated radiotherapy; Molecular targeted agents; Nasopharyngeal carcinoma; Prognostic markers

Indexed keywords

ADENOVIRUS VECTOR; BEVACIZUMAB; CARBOPLATIN; CETUXIMAB; CISPLATIN; DOCETAXEL; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIRUBICIN; EPSTEIN BARR VIRUS ANTIGEN; EPSTEIN BARR VIRUS ANTIGEN 3A; EPSTEIN BARR VIRUS ANTIGEN 3B; EPSTEIN BARR VIRUS ANTIGEN 3C; EPSTEIN BARR VIRUS VACCINE; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; FLUOROURACIL; GEFITINIB; GEMCITABINE; LATENT MEMBRANE PROTEIN 1; LATENT MEMBRANE PROTEIN 2; OXALIPLATIN; PACLITAXEL; SUNITINIB; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR;

EID: 84873373573     PISSN: 11778881     EISSN: None     Source Type: Journal    
DOI: 10.2147/DDDT.S30753     Document Type: Review
Times cited : (152)

References (146)
  • 1
    • 78149362186 scopus 로고    scopus 로고
    • Is nasopharyngeal cancer really a "Cantonese cancer"?
    • Wee JT, Ha TC, Loong SL, Qian CN. Is nasopharyngeal cancer really a "Cantonese cancer"? Chin J Cancer. 2010;29(5):517-526.
    • (2010) Chin J Cancer , vol.29 , Issue.5 , pp. 517-526
    • Wee, J.T.1    Ha, T.C.2    Loong, S.L.3    Qian, C.N.4
  • 3
    • 84871436091 scopus 로고    scopus 로고
    • Intensity-modulated radiation therapy for nasopharyngeal carcinoma: A review
    • Wang TJC, Riaz N, Cheng SK, Lu JJ, Lee NY. Intensity-modulated radiation therapy for nasopharyngeal carcinoma: a review. J Radiat Oncol. 2012;1(2):129-146.
    • (2012) J Radiat Oncol , vol.1 , Issue.2 , pp. 129-146
    • Wang, T.J.C.1    Riaz, N.2    Cheng, S.K.3    Lu, J.J.4    Lee, N.Y.5
  • 4
    • 84862127941 scopus 로고    scopus 로고
    • Current management of nasopharyngeal cancer
    • Lee AW, Lin JC, Ng WT. Current management of nasopharyngeal cancer. Semin Radiat Oncol. 2012;22(3):233-244.
    • (2012) Semin Radiat Oncol , vol.22 , Issue.3 , pp. 233-244
    • Lee, A.W.1    Lin, J.C.2    Ng, W.T.3
  • 5
    • 44449145617 scopus 로고    scopus 로고
    • Systemic approach to improving treatment outcome in nasopharyngeal carcinoma: Current and future directions
    • Ma BB, Hui EP, Chan AT. Systemic approach to improving treatment outcome in nasopharyngeal carcinoma: current and future directions. Cancer Sci. 2008;99(7):1311-1318.
    • (2008) Cancer Sci , vol.99 , Issue.7 , pp. 1311-1318
    • Ma, B.B.1    Hui, E.P.2    Chan, A.T.3
  • 6
    • 0033570936 scopus 로고    scopus 로고
    • Prognostic factors in 677 patients in Singapore with nondisseminated nasopharyngeal carcinoma
    • Heng DM, Wee J, Fong KW, et al. Prognostic factors in 677 patients in Singapore with nondisseminated nasopharyngeal carcinoma. Cancer. 1999;86(10):1912-1920.
    • (1999) Cancer , vol.86 , Issue.10 , pp. 1912-1920
    • Heng, D.M.1    Wee, J.2    Fong, K.W.3
  • 7
    • 0035425402 scopus 로고    scopus 로고
    • Is the 1997 AJCC staging system for nasopharyngeal carcinoma prognostically useful for Chinese patient populations?
    • Ma J, Mai HQ, Hong MH, et al. Is the 1997 AJCC staging system for nasopharyngeal carcinoma prognostically useful for Chinese patient populations? Int J Radiat Oncol Biol Phys. 2001;50(5):1181-1189.
    • (2001) Int J Radiat Oncol Biol Phys , vol.50 , Issue.5 , pp. 1181-1189
    • Ma, J.1    Mai, H.Q.2    Hong, M.H.3
  • 8
    • 20344407787 scopus 로고    scopus 로고
    • Treatment outcomes and late complications of 849 patients with nasopharyngeal carcinoma treated with radiotherapy alone
    • Yeh SA, Tang Y, Lui CC, Huang YJ, Huang EY. Treatment outcomes and late complications of 849 patients with nasopharyngeal carcinoma treated with radiotherapy alone. Int J Radiat Oncol Biol Phys. 2005; 62(3):672-679.
    • (2005) Int J Radiat Oncol Biol Phys , vol.62 , Issue.3 , pp. 672-679
    • Yeh, S.A.1    Tang, Y.2    Lui, C.C.3    Huang, Y.J.4    Huang, E.Y.5
  • 9
    • 0038300485 scopus 로고    scopus 로고
    • In-depth evaluation of the AJCC/UICC 1997 staging system of nasopharyngeal carcinoma: Prognostic homogeneity and proposed refinements
    • Au JS, Law CK, Foo W, Lau WH. In-depth evaluation of the AJCC/UICC 1997 staging system of nasopharyngeal carcinoma: prognostic homogeneity and proposed refinements. Int J Radiat Oncol Biol Phys. 2003;56(2):413-426.
    • (2003) Int J Radiat Oncol Biol Phys , vol.56 , Issue.2 , pp. 413-426
    • Au, J.S.1    Law, C.K.2    Foo, W.3    Lau, W.H.4
  • 10
    • 0035575981 scopus 로고    scopus 로고
    • The predictive value of the 1997 American Joint Committee on Cancer stage classification in determining failure patterns in nasopharyngeal carcinoma
    • Chua DT, Sham JS, Wei WI, Ho WK, Au GK. The predictive value of the 1997 American Joint Committee on Cancer stage classification in determining failure patterns in nasopharyngeal carcinoma. Cancer. 2001;92(11):2845-2855.
    • (2001) Cancer , vol.92 , Issue.11 , pp. 2845-2855
    • Chua, D.T.1    Sham, J.S.2    Wei, W.I.3    Ho, W.K.4    Au, G.K.5
  • 11
    • 21844477623 scopus 로고    scopus 로고
    • Treatment results of 1070 patients with nasopharyngeal carcinoma: An analysis of survival and failure patterns
    • Leung TW, Tung SY, Sze WK, et al. Treatment results of 1070 patients with nasopharyngeal carcinoma: an analysis of survival and failure patterns. Head Neck. 2005;27(7):555-565.
    • (2005) Head Neck , vol.27 , Issue.7 , pp. 555-565
    • Leung, T.W.1    Tung, S.Y.2    Sze, W.K.3
  • 12
    • 20044378115 scopus 로고    scopus 로고
    • Treatment results for nasopharyngeal carcinoma in the modern era: The Hong Kong experience
    • Lee AW, Sze WM, Au JS, et al. Treatment results for nasopharyngeal carcinoma in the modern era: the Hong Kong experience. Int J Radiat Oncol Biol Phys. 2005;61(4):1107-1116.
    • (2005) Int J Radiat Oncol Biol Phys , vol.61 , Issue.4 , pp. 1107-1116
    • Lee, A.W.1    Sze, W.M.2    Au, J.S.3
  • 13
    • 79957556359 scopus 로고    scopus 로고
    • How does intensity-modulated radiotherapy versus conventional two-dimensional radiotherapy influence the treatment results in nasopharyngeal carcinoma patients?
    • Lai SZ, Li WF, Chen L, et al. How does intensity-modulated radiotherapy versus conventional two-dimensional radiotherapy influence the treatment results in nasopharyngeal carcinoma patients? Int J Radiat Oncol Biol Phys. 2011;80(3):661-668.
    • (2011) Int J Radiat Oncol Biol Phys , vol.80 , Issue.3 , pp. 661-668
    • Lai, S.Z.1    Li, W.F.2    Chen, L.3
  • 16
    • 84866593770 scopus 로고    scopus 로고
    • Nasopharyngeal cancer: EHNS-ESMO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up
    • Chan AT, Grégoire V, Lefebvre JL, et al. Nasopharyngeal cancer: EHNS-ESMO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2012;23 Suppl 7:vii83-85.
    • (2012) Ann Oncol , vol.23 , Issue.SUPPL. 7
    • Chan, A.T.1    Grégoire, V.2    Lefebvre, J.L.3
  • 17
    • 35348920121 scopus 로고    scopus 로고
    • 18F-FDG PET can replace conventional work-up in primary M staging of nonkeratinizing nasopharyngeal carcinoma
    • Liu FY, Lin CY, Chang JT, et al. 18F-FDG PET can replace conventional work-up in primary M staging of nonkeratinizing nasopharyngeal carcinoma. J Nucl Med. 2007;48(10):1614-1619.
    • (2007) J Nucl Med , vol.48 , Issue.10 , pp. 1614-1619
    • Liu, F.Y.1    Lin, C.Y.2    Chang, J.T.3
  • 18
    • 84871920376 scopus 로고    scopus 로고
    • Accuracy of whole-body FDG-PET and FDG-PET/CT in M staging of nasopharyngeal carcinoma: A systematic review and meta-analysis
    • Chang MC, Chen JH, Liang JA, Yang KT, Cheng KY, Kao CH. Accuracy of whole-body FDG-PET and FDG-PET/CT in M staging of nasopharyngeal carcinoma: a systematic review and meta-analysis. Eur J Radiol. 2012;82(2):366-373.
    • (2012) Eur J Radiol , vol.82 , Issue.2 , pp. 366-373
    • Chang, M.C.1    Chen, J.H.2    Liang, J.A.3    Yang, K.T.4    Cheng, K.Y.5    Kao, C.H.6
  • 20
    • 84867080820 scopus 로고    scopus 로고
    • The seventh edition of the UICC/AJCC staging system for nasopharyngeal carcinoma is prognostically useful for patients treated with intensity-modulated radiotherapy from an endemic area in China
    • Chen L, Mao YP, Xie FY, et al. The seventh edition of the UICC/AJCC staging system for nasopharyngeal carcinoma is prognostically useful for patients treated with intensity-modulated radiotherapy from an endemic area in China. Radiother Oncol. 2012;104(3):331-337.
    • (2012) Radiother Oncol , vol.104 , Issue.3 , pp. 331-337
    • Chen, L.1    Mao, Y.P.2    Xie, F.Y.3
  • 21
    • 84866414936 scopus 로고    scopus 로고
    • The strength/weakness of the AJCC/UICC staging system (7th edition) for nasopharyngeal cancer and suggestions for future improvement
    • Lee AW, Ng WT, Chan LK, et al. The strength/weakness of the AJCC/UICC staging system (7th edition) for nasopharyngeal cancer and suggestions for future improvement. Oral Oncol. 2012;48(10):1007-1013.
    • (2012) Oral Oncol , vol.48 , Issue.10 , pp. 1007-1013
    • Lee, A.W.1    Ng, W.T.2    Chan, L.K.3
  • 22
    • 2542583455 scopus 로고    scopus 로고
    • Primary tumor volume of nasopharyngeal carcinoma: Prognostic significance for local control
    • Sze WM, Lee AW, Yau TK, et al. Primary tumor volume of nasopharyngeal carcinoma: prognostic significance for local control. Int J Radiat Oncol Biol Phys. 2004;59(1):21-27.
    • (2004) Int J Radiat Oncol Biol Phys , vol.59 , Issue.1 , pp. 21-27
    • Sze, W.M.1    Lee, A.W.2    Yau, T.K.3
  • 23
    • 0036786846 scopus 로고    scopus 로고
    • The effect of primary tumor volumes in advanced T-staged nasopharyngeal tumors
    • Chang CC, Chen MK, Liu MT, Wu HK. The effect of primary tumor volumes in advanced T-staged nasopharyngeal tumors. Head Neck. 2002;24(10):940-946.
    • (2002) Head Neck , vol.24 , Issue.10 , pp. 940-946
    • Chang, C.C.1    Chen, M.K.2    Liu, M.T.3    Wu, H.K.4
  • 24
    • 84867058809 scopus 로고    scopus 로고
    • Is primary tumor volume still a prognostic factor in intensity modulated radiation therapy for nasopharyngeal carcinoma?
    • Guo R, Sun Y, Yu XL, et al. Is primary tumor volume still a prognostic factor in intensity modulated radiation therapy for nasopharyngeal carcinoma? Radiother Oncol. 2012;104(3):294-299.
    • (2012) Radiother Oncol , vol.104 , Issue.3 , pp. 294-299
    • Guo, R.1    Sun, Y.2    Yu, X.L.3
  • 25
    • 84876036903 scopus 로고    scopus 로고
    • Prognostic significance of tumor volume in patients with nasopharyngeal carcinoma undergoing intensity-modulated radiation therapy
    • Epub June 19
    • Wu Z, Zeng RF, Su Y, Gu MF, Huang SM. Prognostic significance of tumor volume in patients with nasopharyngeal carcinoma undergoing intensity-modulated radiation therapy. Head Neck. Epub June 19, 2012.
    • (2012) Head Neck
    • Wu, Z.1    Zeng, R.F.2    Su, Y.3    Gu, M.F.4    Huang, S.M.5
  • 26
    • 14744278443 scopus 로고    scopus 로고
    • Has survival improved for nasopharyngeal carcinoma in the United States?
    • Lee JT, Ko CY. Has survival improved for nasopharyngeal carcinoma in the United States? Otolaryngol Head Neck Surg. 2005;132(2): 303-308.
    • (2005) Otolaryngol Head Neck Surg , vol.132 , Issue.2 , pp. 303-308
    • Lee, J.T.1    Ko, C.Y.2
  • 27
    • 33847742531 scopus 로고    scopus 로고
    • Plasma Epstein-Barr viral deoxyribonucleic acid quantitation complements tumor-node-metastasis staging prognostication in nasopharyngeal carcinoma
    • Leung SF, Zee B, Ma BB, et al. Plasma Epstein-Barr viral deoxyribonucleic acid quantitation complements tumor-node-metastasis staging prognostication in nasopharyngeal carcinoma. J Clin Oncol. 2006; 24(34):5414-5418.
    • (2006) J Clin Oncol , vol.24 , Issue.34 , pp. 5414-5418
    • Leung, S.F.1    Zee, B.2    Ma, B.B.3
  • 28
    • 0037669569 scopus 로고    scopus 로고
    • Pretherapy quantitative measurement of circulating Epstein-Barr virus DNA is predictive of posttherapy distant failure in patients with early-stage nasopharyngeal carcinoma of undifferentiated type
    • Leung SF, Chan ATC, Zee B, et al. Pretherapy quantitative measurement of circulating Epstein-Barr virus DNA is predictive of posttherapy distant failure in patients with early-stage nasopharyngeal carcinoma of undifferentiated type. Cancer. 2003;98(2):288-291.
    • (2003) Cancer , vol.98 , Issue.2 , pp. 288-291
    • Leung, S.F.1    Chan, A.T.C.2    Zee, B.3
  • 29
    • 0037032506 scopus 로고    scopus 로고
    • Plasma Epstein-Barr virus DNA and residual disease after radiotherapy for undifferentiated nasopharyngeal carcinoma
    • Chan AT, Lo YM, Zee B, et al. Plasma Epstein-Barr virus DNA and residual disease after radiotherapy for undifferentiated nasopharyngeal carcinoma. J Natl Cancer Inst. 2002;94(21):1614-1619.
    • (2002) J Natl Cancer Inst , vol.94 , Issue.21 , pp. 1614-1619
    • Chan, A.T.1    Lo, Y.M.2    Zee, B.3
  • 30
    • 2942607684 scopus 로고    scopus 로고
    • Quantification of plasma Epstein-Barr virus DNA in patients with advanced nasopharyngeal carcinoma
    • Lin JC, Wang WY, Chen KY, et al. Quantification of plasma Epstein-Barr virus DNA in patients with advanced nasopharyngeal carcinoma. N Engl J Med. 2004;350(24):2461-2470.
    • (2004) N Engl J Med , vol.350 , Issue.24 , pp. 2461-2470
    • Lin, J.C.1    Wang, W.Y.2    Chen, K.Y.3
  • 31
    • 33750957265 scopus 로고    scopus 로고
    • Radiological, pathological and DNA remission in recurrent metastatic nasopharyngeal carcinoma
    • Chan SL, Hui EP, Leung SF, et al. Radiological, pathological and DNA remission in recurrent metastatic nasopharyngeal carcinoma. BMC Cancer. 2006;6:259.
    • (2006) BMC Cancer , vol.6 , pp. 259
    • Chan, S.L.1    Hui, E.P.2    Leung, S.F.3
  • 32
    • 34249097816 scopus 로고    scopus 로고
    • Testing for excision repair cross-complementing 1 in patients with non-small-cell lung cancer for chemotherapy response
    • Felip E, Rosell R. Testing for excision repair cross-complementing 1 in patients with non-small-cell lung cancer for chemotherapy response. Exp Rev Mol Diagn. 2007;7(3):261-268.
    • (2007) Exp Rev Mol Diagn , vol.7 , Issue.3 , pp. 261-268
    • Felip, E.1    Rosell, R.2
  • 33
    • 79957570471 scopus 로고    scopus 로고
    • Expression of excision repair cross-complementation group 1 as predictive marker for nasopharyngeal cancer treated with concurrent chemoradiotherapy
    • Sun JM, Ahn MJ, Park MJ, et al. Expression of excision repair cross-complementation group 1 as predictive marker for nasopharyngeal cancer treated with concurrent chemoradiotherapy. Int J Radiat Oncol Biol Phys. 2011;80(3):655-660.
    • (2011) Int J Radiat Oncol Biol Phys , vol.80 , Issue.3 , pp. 655-660
    • Sun, J.M.1    Ahn, M.J.2    Park, M.J.3
  • 34
    • 79952694711 scopus 로고    scopus 로고
    • Can the analysis of ERCC1 expression contribute to individualized therapy in nasopharyngeal carcinoma?
    • Chan SH, Cheung FM, Ng WT, et al. Can the analysis of ERCC1 expression contribute to individualized therapy in nasopharyngeal carcinoma? Int J Radiat Oncol Biol Phys. 2011;79(5):1414-1420.
    • (2011) Int J Radiat Oncol Biol Phys , vol.79 , Issue.5 , pp. 1414-1420
    • Chan, S.H.1    Cheung, F.M.2    Ng, W.T.3
  • 35
    • 84866405470 scopus 로고    scopus 로고
    • Expression of ERCC1 predicts clinical outcome in locoregionally advanced nasopharyngeal carcinoma treated with cisplatin-based induction chemotherapy
    • Huang PY, Li Y, Mai HQ, et al. Expression of ERCC1 predicts clinical outcome in locoregionally advanced nasopharyngeal carcinoma treated with cisplatin-based induction chemotherapy. Oral Oncol. 2012;48(10):964-968.
    • (2012) Oral Oncol , vol.48 , Issue.10 , pp. 964-968
    • Huang, P.Y.1    Li, Y.2    Mai, H.Q.3
  • 36
    • 40949149466 scopus 로고    scopus 로고
    • Evidence behind use of intensity-modulated radiotherapy: A systematic review of comparative clinical studies
    • Veldeman L, Madani I, Hulstaert F, De Meerleer G, Mareel M, De Neve W. Evidence behind use of intensity-modulated radiotherapy: a systematic review of comparative clinical studies. Lancet Oncol. 2008;9(4):367-375.
    • (2008) Lancet Oncol , vol.9 , Issue.4 , pp. 367-375
    • Veldeman, L.1    Madani, I.2    Hulstaert, F.3    de Meerleer, G.4    Mareel, M.5    de Neve, W.6
  • 37
    • 0036569761 scopus 로고    scopus 로고
    • Intensity-modulated radiotherapy in the treatment of nasopharyngeal carcinoma: An update of the UCSF experience
    • Lee N, Xia P, Quivey JM, et al. Intensity-modulated radiotherapy in the treatment of nasopharyngeal carcinoma: an update of the UCSF experience. Int J Radiat Oncol Biol Phys. 2002;53(1):12-22.
    • (2002) Int J Radiat Oncol Biol Phys , vol.53 , Issue.1 , pp. 12-22
    • Lee, N.1    Xia, P.2    Quivey, J.M.3
  • 38
    • 10044257645 scopus 로고    scopus 로고
    • Treatment of nasopharyngeal carcinoma with intensity-modulated radiotherapy: The Hong Kong experience
    • Kam MK, Teo PM, Chau RM, et al. Treatment of nasopharyngeal carcinoma with intensity-modulated radiotherapy: the Hong Kong experience. Int J Radiat Oncol Biol Phys. 2004;60(5):1440-1450.
    • (2004) Int J Radiat Oncol Biol Phys , vol.60 , Issue.5 , pp. 1440-1450
    • Kam, M.K.1    Teo, P.M.2    Chau, R.M.3
  • 39
    • 29244459121 scopus 로고    scopus 로고
    • Intensity-modulated radiation therapy (IMRT) for nasopharynx cancer: Update of the Memorial Sloan-Kettering experience
    • Wolden SL, Chen WC, Pfster DG, et al. Intensity-modulated radiation therapy (IMRT) for nasopharynx cancer: update of the Memorial Sloan-Kettering experience. Int J Radiat Oncol Biol Phys. 2006;64(1): 57-62.
    • (2006) Int J Radiat Oncol Biol Phys , vol.64 , Issue.1 , pp. 57-62
    • Wolden, S.L.1    Chen, W.C.2    Pfster, D.G.3
  • 40
    • 30544442262 scopus 로고    scopus 로고
    • Preliminary results of radiation dose escalation for locally advanced nasopharyngeal carcinoma
    • Kwong DL, Sham JS, Leung LH, et al. Preliminary results of radiation dose escalation for locally advanced nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 2006;64(2):374-381.
    • (2006) Int J Radiat Oncol Biol Phys , vol.64 , Issue.2 , pp. 374-381
    • Kwong, D.L.1    Sham, J.S.2    Leung, L.H.3
  • 41
    • 79954420340 scopus 로고    scopus 로고
    • Hypofractionated dose-painting intensity modulated radiation therapy with chemotherapy for nasopharyngeal carcinoma: A prospective trial
    • Bakst RL, Lee N, Pfister DG, et al. Hypofractionated dose-painting intensity modulated radiation therapy with chemotherapy for nasopharyngeal carcinoma: a prospective trial. Int J Radiat Oncol Biol Phys. 2011;80(1):148-153.
    • (2011) Int J Radiat Oncol Biol Phys , vol.80 , Issue.1 , pp. 148-153
    • Bakst, R.L.1    Lee, N.2    Pfister, D.G.3
  • 42
    • 84860448909 scopus 로고    scopus 로고
    • A phase II study of concurrrent cetuximab-cisplatin and intensity-modulated radiotherapy in locoregionally advanced nasopharyngeal carcinoma
    • Ma BB, Kam MK, Leung SF, et al. A phase II study of concurrrent cetuximab-cisplatin and intensity-modulated radiotherapy in locoregionally advanced nasopharyngeal carcinoma. Ann Oncol. 2012;23(5): 1287-1292.
    • (2012) Ann Oncol , vol.23 , Issue.5 , pp. 1287-1292
    • Ma, B.B.1    Kam, M.K.2    Leung, S.F.3
  • 43
    • 71649105983 scopus 로고    scopus 로고
    • Treatment of nasopharyngeal carcinoma using intensity-modulated radiotherapy - the National Cancer Centre Singapore Experience
    • Tham IW, Hee SW, Yeo RM, et al. Treatment of nasopharyngeal carcinoma using intensity-modulated radiotherapy - the National Cancer Centre Singapore Experience. Int J Radiat Oncol Biol Phys. 2009;75(5):1481-1486.
    • (2009) Int J Radiat Oncol Biol Phys , vol.75 , Issue.5 , pp. 1481-1486
    • Tham, I.W.1    Hee, S.W.2    Yeo, R.M.3
  • 44
    • 70350613966 scopus 로고    scopus 로고
    • Nasopharyngeal carcinoma treated with reduced-volume intensity-modulated radiation therapy: Report on the 3-year outcome of a prospective series
    • Lin S, Pan J, Han L, et al. Nasopharyngeal carcinoma treated with reduced-volume intensity-modulated radiation therapy: report on the 3-year outcome of a prospective series. Int J Radiat Oncol Biol Phys. 2009;75(4):1071-1078.
    • (2009) Int J Radiat Oncol Biol Phys , vol.75 , Issue.4 , pp. 1071-1078
    • Lin, S.1    Pan, J.2    Han, L.3
  • 45
    • 68949083598 scopus 로고    scopus 로고
    • Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: Radiation therapy oncology group phase II trial 0225
    • Lee N, Harris J, Garden AS, et al. Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225. J Clin Oncol. 2009;27(22):3684-3690.
    • (2009) J Clin Oncol , vol.27 , Issue.22 , pp. 3684-3690
    • Lee, N.1    Harris, J.2    Garden, A.S.3
  • 46
    • 72049091457 scopus 로고    scopus 로고
    • Whole-field simultaneous integrated-boost intensity-modulated radiotherapy for patients with nasopharyngeal carcinoma
    • Wong FC, Ng AW, Lee VH, et al. Whole-field simultaneous integrated-boost intensity-modulated radiotherapy for patients with nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 2010;76(1): 138-145.
    • (2010) Int J Radiat Oncol Biol Phys , vol.76 , Issue.1 , pp. 138-145
    • Wong, F.C.1    Ng, A.W.2    Lee, V.H.3
  • 47
    • 78650838398 scopus 로고    scopus 로고
    • Clinical outcomes and patterns of failure after intensity-modulated radiotherapy for nasopharyngeal carcinoma
    • Ng WT, Lee MC, Hung WM, et al. Clinical outcomes and patterns of failure after intensity-modulated radiotherapy for nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 2011;79(2):420-428.
    • (2011) Int J Radiat Oncol Biol Phys , vol.79 , Issue.2 , pp. 420-428
    • Ng, W.T.1    Lee, M.C.2    Hung, W.M.3
  • 48
    • 79955435781 scopus 로고    scopus 로고
    • Local control, survival, and late toxicities of locally advanced nasopharyngeal carcinoma treated by simultaneous modulated accelerated radiotherapy combined with cisplatin concurrent chemotherapy: Long-term results of a phase 2 study
    • Xiao WW, Huang SM, Han F, et al. Local control, survival, and late toxicities of locally advanced nasopharyngeal carcinoma treated by simultaneous modulated accelerated radiotherapy combined with cisplatin concurrent chemotherapy: long-term results of a phase 2 study. Cancer. 2011;117(9):1874-1883.
    • (2011) Cancer , vol.117 , Issue.9 , pp. 1874-1883
    • Xiao, W.W.1    Huang, S.M.2    Han, F.3
  • 49
    • 83955161808 scopus 로고    scopus 로고
    • Long-term outcomes of early-stage nasopharyngeal carcinoma patients treated with intensity-modulated radiotherapy alone
    • Su SF, Han F, Zhao C, et al. Long-term outcomes of early-stage nasopharyngeal carcinoma patients treated with intensity-modulated radiotherapy alone. Int J Radiat Oncol Biol Phys. 2012;82(1): 327-333.
    • (2012) Int J Radiat Oncol Biol Phys , vol.82 , Issue.1 , pp. 327-333
    • Su, S.F.1    Han, F.2    Zhao, C.3
  • 50
    • 84856481199 scopus 로고    scopus 로고
    • Addition of bevacizumab to standard chemoradiation for locoregionally advanced nasopharyngeal carcinoma (RTOG 0615): A phase 2 multi-institutional trial
    • Lee N, Zhang Q, Kim J, et al. Addition of bevacizumab to standard chemoradiation for locoregionally advanced nasopharyngeal carcinoma (RTOG 0615): a phase 2 multi-institutional trial. Lancet Oncol. 2012;13(2):172-180.
    • (2012) Lancet Oncol , vol.13 , Issue.2 , pp. 172-180
    • Lee, N.1    Zhang, Q.2    Kim, J.3
  • 51
    • 77956703524 scopus 로고    scopus 로고
    • Controversies and challenges in the current management of nasopharyngeal cancer
    • Tham IW, Lu JJ. Controversies and challenges in the current management of nasopharyngeal cancer. Expert Rev Anticancer Ther. 2010; 10(9):1439-1450.
    • (2010) Expert Rev Anticancer Ther , vol.10 , Issue.9 , pp. 1439-1450
    • Tham, I.W.1    Lu, J.J.2
  • 52
    • 0023866398 scopus 로고
    • Analysis of 1379 patients with nasopharyngeal carcinoma treated by radiation
    • Qin DX, Hu YH, Yan JH, et al. Analysis of 1379 patients with nasopharyngeal carcinoma treated by radiation. Cancer. 1988;61(6): 1117-1124.
    • (1988) Cancer , vol.61 , Issue.6 , pp. 1117-1124
    • Qin, D.X.1    Hu, Y.H.2    Yan, J.H.3
  • 53
    • 60049092026 scopus 로고    scopus 로고
    • The volume to be irradiated during selective neck irradiation in nasopharyngeal carcinoma: Analysis of the spread patterns in lymph nodes by magnetic resonance imaging
    • Tang LL, Mao Y, Liu L, et al. The volume to be irradiated during selective neck irradiation in nasopharyngeal carcinoma: analysis of the spread patterns in lymph nodes by magnetic resonance imaging. Cancer. 2009;115(3):680-688.
    • (2009) Cancer , vol.115 , Issue.3 , pp. 680-688
    • Tang, L.L.1    Mao, Y.2    Liu, L.3
  • 54
    • 77955495419 scopus 로고    scopus 로고
    • Is elective irradiation to the lower neck necessary for N0 nasopharyngeal carcinoma?
    • Gao Y, Zhu G, Lu J, et al. Is elective irradiation to the lower neck necessary for N0 nasopharyngeal carcinoma? Int J Radiat Oncol Biol Phys. 2010;77(5):1397-1402.
    • (2010) Int J Radiat Oncol Biol Phys , vol.77 , Issue.5 , pp. 1397-1402
    • Gao, Y.1    Zhu, G.2    Lu, J.3
  • 55
    • 84866408697 scopus 로고    scopus 로고
    • Treatment outcome of nasopharyngeal carcinoma with retropharyngeal lymph nodes metastasis only and the feasibility of elective neck irradiation
    • Ou X, Shen C, Kong L, et al. Treatment outcome of nasopharyngeal carcinoma with retropharyngeal lymph nodes metastasis only and the feasibility of elective neck irradiation. Oral Oncol. 2012;48(10): 1045-1050.
    • (2012) Oral Oncol , vol.48 , Issue.10 , pp. 1045-1050
    • Ou, X.1    Shen, C.2    Kong, L.3
  • 56
    • 84875221625 scopus 로고    scopus 로고
    • Results of a phase 2 study examining the effects of omitting elective neck irradiation to nodal levels IV and V(b) in patients with N(0-1) nasopharyngeal carcinoma
    • Epub September 10
    • Chen JZ, Le QT, Han F, et al. Results of a phase 2 study examining the effects of omitting elective neck irradiation to nodal levels IV and V(b) in patients with N(0-1) nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. Epub September 10, 2012.
    • (2012) Int J Radiat Oncol Biol Phys
    • Chen, J.Z.1    Le, Q.T.2    Han, F.3
  • 57
    • 33750357039 scopus 로고    scopus 로고
    • Xerostomia and quality of life after intensity-modulated radiotherapy vs conventional radiotherapy for early-stage nasopharyngeal carcinoma: Initial report on a randomized controlled clinical trial
    • Pow EH, Kwong DL, McMillan AS, et al. Xerostomia and quality of life after intensity-modulated radiotherapy vs conventional radiotherapy for early-stage nasopharyngeal carcinoma: initial report on a randomized controlled clinical trial. Int Radiat Oncol Biol Phys. 2006;66(4): 981-991.
    • (2006) Int Radiat Oncol Biol Phys , vol.66 , Issue.4 , pp. 981-991
    • Pow, E.H.1    Kwong, D.L.2    McMillan, A.S.3
  • 58
    • 36849010786 scopus 로고    scopus 로고
    • Prospective randomized study of intensity-modulated radiotherapy on salivary gland function in early-stage nasopharyngeal carcinoma patients
    • Kam MK, Leung SF, Zee B, et al. Prospective randomized study of intensity-modulated radiotherapy on salivary gland function in early-stage nasopharyngeal carcinoma patients. J Clin Oncol. 2007;25(31): 4873-4879.
    • (2007) J Clin Oncol , vol.25 , Issue.31 , pp. 4873-4879
    • Kam, M.K.1    Leung, S.F.2    Zee, B.3
  • 59
    • 78149357305 scopus 로고    scopus 로고
    • Multivariate analysis of quality of life outcome for nasopharyngeal carcinoma patients after treatment
    • Fang FM, Tsai WL, Lee TF, Liao KC, Chen HC, Hsu HC. Multivariate analysis of quality of life outcome for nasopharyngeal carcinoma patients after treatment. Radiother Oncol. 2010;97(2):263-269.
    • (2010) Radiother Oncol , vol.97 , Issue.2 , pp. 263-269
    • Fang, F.M.1    Tsai, W.L.2    Lee, T.F.3    Liao, K.C.4    Chen, H.C.5    Hsu, H.C.6
  • 60
    • 70449623549 scopus 로고    scopus 로고
    • A study of middle ear function in the treatment of nasopharyngeal carcinoma with IMRT technique
    • Wang SZ, Li J, Miyamoto CT, et al. A study of middle ear function in the treatment of nasopharyngeal carcinoma with IMRT technique. Radiother Oncol. 2009;93(3):530-533.
    • (2009) Radiother Oncol , vol.93 , Issue.3 , pp. 530-533
    • Wang, S.Z.1    Li, J.2    Miyamoto, C.T.3
  • 61
    • 16344389019 scopus 로고    scopus 로고
    • Prospective study of inner ear radiation dose and hearing loss in head-and-neck cancer patients
    • Pan CC, Eisbruch A, Lee JS, et al. Prospective study of inner ear radiation dose and hearing loss in head-and-neck cancer patients. Int J Radiat Oncol Biol Phys. 2005;61(5):1393-1402.
    • (2005) Int J Radiat Oncol Biol Phys , vol.61 , Issue.5 , pp. 1393-1402
    • Pan, C.C.1    Eisbruch, A.2    Lee, J.S.3
  • 62
    • 61349183760 scopus 로고    scopus 로고
    • Major late toxicities after conformal radiotherapy for nasopharyngeal carcinoma-patient-and-treatment-related risk factors
    • Lee AW, Ng WT, Hung WM, et al. Major late toxicities after conformal radiotherapy for nasopharyngeal carcinoma-patient-and-treatment-related risk factors. Int J Radiat Oncol Biol Phys. 2009;73(4): 1121-1128.
    • (2009) Int J Radiat Oncol Biol Phys , vol.73 , Issue.4 , pp. 1121-1128
    • Lee, A.W.1    Ng, W.T.2    Hung, W.M.3
  • 63
    • 84866426836 scopus 로고    scopus 로고
    • Late toxicities after conventional radiation therapy alone for nasopharyngeal carcinoma
    • Tuan JK, Ha TC, Ong WS, et al. Late toxicities after conventional radiation therapy alone for nasopharyngeal carcinoma. Radiother Oncol. 2012;104(3):305-311.
    • (2012) Radiother Oncol , vol.104 , Issue.3 , pp. 305-311
    • Tuan, J.K.1    Ha, T.C.2    Ong, W.S.3
  • 64
    • 0029075950 scopus 로고
    • Effect of time, dose and fractionation on local control of nasopharyngeal carcinoma
    • Lee AW, Chan DK, Fowler JF, et al. Effect of time, dose and fractionation on local control of nasopharyngeal carcinoma. Radiother Oncol. 1995;36(1):24-31.
    • (1995) Radiother Oncol , vol.36 , Issue.1 , pp. 24-31
    • Lee, A.W.1    Chan, D.K.2    Fowler, J.F.3
  • 65
    • 0036570252 scopus 로고    scopus 로고
    • Factors affecting risk of symptomatic temporal lobe necrosis: Significance of fractional dose and treatment time
    • Lee AW, Kwong DL, Leung SF. Factors affecting risk of symptomatic temporal lobe necrosis: significance of fractional dose and treatment time. Int J Radiat Oncol Biol Phys. 2002;53(1):75-85.
    • (2002) Int J Radiat Oncol Biol Phys , vol.53 , Issue.1 , pp. 75-85
    • Lee, A.W.1    Kwong, D.L.2    Leung, S.F.3
  • 66
    • 79952170023 scopus 로고    scopus 로고
    • Delayed cervicobulbar neuronopathy and myokymia after head and neck radiotherapy for nasopharyngeal carcinoma: A case report
    • Rison RA, Beydoun SR. Delayed cervicobulbar neuronopathy and myokymia after head and neck radiotherapy for nasopharyngeal carcinoma: a case report. J Clin Neuromuscul Dis. 2011;12(3): 147-152.
    • (2011) J Clin Neuromuscul Dis , vol.12 , Issue.3 , pp. 147-152
    • Rison, R.A.1    Beydoun, S.R.2
  • 67
    • 0037664988 scopus 로고    scopus 로고
    • Treatment outcome after radiotherapy alone for patients with stage I-II nasopharyngeal carcinoma
    • Chua DT, Sham JS, Kwong DL, Au GK. Treatment outcome after radiotherapy alone for patients with stage I-II nasopharyngeal carcinoma. Cancer. 2003;98(1):74-80.
    • (2003) Cancer , vol.98 , Issue.1 , pp. 74-80
    • Chua, D.T.1    Sham, J.S.2    Kwong, D.L.3    Au, G.K.4
  • 68
    • 67649566412 scopus 로고    scopus 로고
    • Treatment outcomes after radiotherapy alone for patients with early-stage nasopharyngeal carcinoma
    • Xiao WW, Han F, Lu TX, Chen CY, Huang Y, Zhao C. Treatment outcomes after radiotherapy alone for patients with early-stage nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 2009;74(4): 1070-1076.
    • (2009) Int J Radiat Oncol Biol Phys , vol.74 , Issue.4 , pp. 1070-1076
    • Xiao, W.W.1    Han, F.2    Lu, T.X.3    Chen, C.Y.4    Huang, Y.5    Zhao, C.6
  • 69
    • 0037669569 scopus 로고    scopus 로고
    • Pretherapy quantitative measurement of circulating Epstein-Barr virus DNA is predictive of posttherapy distant failure in patients with early-stage nasopharyngeal carcinoma of undifferentiated type
    • Leung SF, Chan AT, Zee B, et al. Pretherapy quantitative measurement of circulating Epstein-Barr virus DNA is predictive of posttherapy distant failure in patients with early-stage nasopharyngeal carcinoma of undifferentiated type. Cancer. 2003;98(2):288-291.
    • (2003) Cancer , vol.98 , Issue.2 , pp. 288-291
    • Leung, S.F.1    Chan, A.T.2    Zee, B.3
  • 70
    • 0031947875 scopus 로고    scopus 로고
    • Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: Phase III randomized Intergroup study 0099
    • Al-Sarraf M, LeBlanc M, Giri PG, et al. Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: phase III randomized Intergroup study 0099. J Clin Oncol. 1998;16(4): 1310-1317.
    • (1998) J Clin Oncol , vol.16 , Issue.4 , pp. 1310-1317
    • Al-Sarraf, M.1    Leblanc, M.2    Giri, P.G.3
  • 71
    • 84862791007 scopus 로고    scopus 로고
    • Promising treatment outcomes of intensity-modulated radiation therapy for nasopharyngeal carcinoma patients with N0 disease according to the seventh edition of the AJCC staging system
    • Sun Y, Tang LL, Chen L, et al. Promising treatment outcomes of intensity-modulated radiation therapy for nasopharyngeal carcinoma patients with N0 disease according to the seventh edition of the AJCC staging system. BMC Cancer. 2012;12:68.
    • (2012) BMC Cancer , vol.12 , pp. 68
    • Sun, Y.1    Tang, L.L.2    Chen, L.3
  • 72
    • 33748579563 scopus 로고    scopus 로고
    • Improvement of survival after addition of induction chemotherapy to radiotherapy in patients with early-stage nasopharyngeal carcinoma: Subgroup analysis of two phase III trials
    • Chua DT, Ma J, Sham JS, et al. Improvement of survival after addition of induction chemotherapy to radiotherapy in patients with early-stage nasopharyngeal carcinoma: subgroup analysis of two phase III trials. Int J Radiat Oncol Biol Phys. 2006;65(5):1300-1306.
    • (2006) Int J Radiat Oncol Biol Phys , vol.65 , Issue.5 , pp. 1300-1306
    • Chua, D.T.1    Ma, J.2    Sham, J.S.3
  • 73
    • 4444256753 scopus 로고    scopus 로고
    • Another way to estimate outcome of advanced nasopharyngeal carcinoma - is concurrent chemoradiotherapy adequate?
    • Lin JC, Liang WM, Jan JS, Jiang RS, Lin AC. Another way to estimate outcome of advanced nasopharyngeal carcinoma - is concurrent chemoradiotherapy adequate? Int J Radiat Oncol Biol Phys. 2004;60(1): 156-164.
    • (2004) Int J Radiat Oncol Biol Phys , vol.60 , Issue.1 , pp. 156-164
    • Lin, J.C.1    Liang, W.M.2    Jan, J.S.3    Jiang, R.S.4    Lin, A.C.5
  • 74
    • 17144443321 scopus 로고    scopus 로고
    • Concomitant radiotherapy and chemotherapy for early-stage nasopharyngeal carcinoma
    • Cheng SH, Tsai SY, Yen KL, et al. Concomitant radiotherapy and chemotherapy for early-stage nasopharyngeal carcinoma. J Clin Oncol. 2000;18(10):2040-2045.
    • (2000) J Clin Oncol , vol.18 , Issue.10 , pp. 2040-2045
    • Cheng, S.H.1    Tsai, S.Y.2    Yen, K.L.3
  • 75
    • 83255173935 scopus 로고    scopus 로고
    • Concurrent chemoradiotherapy vs radiotherapy alone in stage II nasopharyngeal carcinoma: Phase iii randomized trial
    • Chen QY, Wen YF, Guo L, et al. Concurrent chemoradiotherapy vs radiotherapy alone in stage II nasopharyngeal carcinoma: phase iii randomized trial. J Natl Cancer Inst. 2011;103(23):1761-1770.
    • (2011) J Natl Cancer Inst , vol.103 , Issue.23 , pp. 1761-1770
    • Chen, Q.Y.1    Wen, Y.F.2    Guo, L.3
  • 76
    • 27244452301 scopus 로고    scopus 로고
    • Randomized trial of radiotherapy versus concurrent chemoradiotherapy followed by adjuvant chemotherapy in patients with American Joint Committee on Cancer/International Union against cancer stage III and IV nasopharyngeal cancer of the endemic variety
    • Wee J, Tan EH, Tai BC, et al. Randomized trial of radiotherapy versus concurrent chemoradiotherapy followed by adjuvant chemotherapy in patients with American Joint Committee on Cancer/International Union against cancer stage III and IV nasopharyngeal cancer of the endemic variety. J Clin Oncol. 2005;23(27):6730-6738.
    • (2005) J Clin Oncol , vol.23 , Issue.27 , pp. 6730-6738
    • Wee, J.1    Tan, E.H.2    Tai, B.C.3
  • 77
    • 77955445967 scopus 로고    scopus 로고
    • Randomized trial of radiotherapy plus concurrent-adjuvant chemotherapy vs radiotherapy alone for locoregionally advanced nasopharyngeal carcinoma
    • Lee AW, Tung SY, Chua DT, et al. Randomized trial of radiotherapy plus concurrent-adjuvant chemotherapy vs radiotherapy alone for locoregionally advanced nasopharyngeal carcinoma. J Natl Cancer Inst. 2010;102(15):1188-1198.
    • (2010) J Natl Cancer Inst , vol.102 , Issue.15 , pp. 1188-1198
    • Lee, A.W.1    Tung, S.Y.2    Chua, D.T.3
  • 78
    • 47149084927 scopus 로고    scopus 로고
    • Preliminary results of a prospective randomized trial comparing concurrent chemoradiotherapy plus adjuvant chemotherapy with radiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma in endemic regions of China
    • Chen Y, Liu MZ, Liang SB, et al. Preliminary results of a prospective randomized trial comparing concurrent chemoradiotherapy plus adjuvant chemotherapy with radiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma in endemic regions of China. Int J Radiat Oncol Biol Phys. 2008;71(5):1356-1364.
    • (2008) Int J Radiat Oncol Biol Phys , vol.71 , Issue.5 , pp. 1356-1364
    • Chen, Y.1    Liu, M.Z.2    Liang, S.B.3
  • 79
    • 78651367213 scopus 로고    scopus 로고
    • A randomized trial on addition of concurrent-adjuvant chemotherapy and/or accelerated fractionation for locally advanced nasopharyngeal carcinoma
    • Lee AW, Tung SY, Chan AT, et al. A randomized trial on addition of concurrent-adjuvant chemotherapy and/or accelerated fractionation for locally advanced nasopharyngeal carcinoma. Radiother Oncol. 2011;98(1):15-22.
    • (2011) Radiother Oncol , vol.98 , Issue.1 , pp. 15-22
    • Lee, A.W.1    Tung, S.Y.2    Chan, A.T.3
  • 80
    • 0037441720 scopus 로고    scopus 로고
    • Phase III study of concurrent chemoradiotherapy versus radiotherapy alone for advanced nasopharyngeal carcinoma: Positive effect on overall and progression-free survival
    • Lin JC, Jan JS, Hsu CY, Liang WM, Jiang RS, Wang WY. Phase III study of concurrent chemoradiotherapy versus radiotherapy alone for advanced nasopharyngeal carcinoma: positive effect on overall and progression-free survival. J Clin Oncol. 2003;21(4):631-637.
    • (2003) J Clin Oncol , vol.21 , Issue.4 , pp. 631-637
    • Lin, J.C.1    Jan, J.S.2    Hsu, C.Y.3    Liang, W.M.4    Jiang, R.S.5    Wang, W.Y.6
  • 81
    • 15944417086 scopus 로고    scopus 로고
    • Overall survival after concurrent cisplatin-radiotherapy compared with radiotherapy alone in locoregionally advanced nasopharyngeal carcinoma
    • Chan AT, Ngan RK, Teo PM, et al. Overall survival after concurrent cisplatin-radiotherapy compared with radiotherapy alone in locoregionally advanced nasopharyngeal carcinoma. J Natl Cancer Inst. 2005;97(7):536-539.
    • (2005) J Natl Cancer Inst , vol.97 , Issue.7 , pp. 536-539
    • Chan, A.T.1    Ngan, R.K.2    Teo, P.M.3
  • 82
    • 33644668130 scopus 로고    scopus 로고
    • Phase III study comparing standard radiotherapy with or without weekly oxaliplatin in treatment of locoregionally advanced nasopharyngeal carcinoma: Preliminary results
    • Zhang L, Zhao C, Peng PJ, et al. Phase III study comparing standard radiotherapy with or without weekly oxaliplatin in treatment of locoregionally advanced nasopharyngeal carcinoma: preliminary results. J Clin Oncol. 2005;23(33):8461-8468.
    • (2005) J Clin Oncol , vol.23 , Issue.33 , pp. 8461-8468
    • Zhang, L.1    Zhao, C.2    Peng, P.J.3
  • 83
    • 4344709667 scopus 로고    scopus 로고
    • Concurrent and adjuvant chemotherapy for nasopharyngeal carcinoma: A factorial study
    • Kwong DL, Sham JS, Au GK, et al. Concurrent and adjuvant chemotherapy for nasopharyngeal carcinoma: a factorial study. J Clin Oncol. 2004;22(13):2643-2653.
    • (2004) J Clin Oncol , vol.22 , Issue.13 , pp. 2643-2653
    • Kwong, D.L.1    Sham, J.S.2    Au, G.K.3
  • 84
    • 34249886296 scopus 로고    scopus 로고
    • Chemoradiation comparing cisplatin versus carboplatin in locally advanced nasopharyngeal cancer: Randomised, non-inferiority, open trial
    • Chitapanarux I, Lorvidhaya V, Kamnerdsupaphon P, et al. Chemoradiation comparing cisplatin versus carboplatin in locally advanced nasopharyngeal cancer: randomised, non-inferiority, open trial. Eur J Cancer. 2007;43(9):1399-1406.
    • (2007) Eur J Cancer , vol.43 , Issue.9 , pp. 1399-1406
    • Chitapanarux, I.1    Lorvidhaya, V.2    Kamnerdsupaphon, P.3
  • 85
    • 33750283687 scopus 로고    scopus 로고
    • Treatment of stage IV(A-B) nasopharyngeal carcinoma by induction-concurrent chemoradiotherapy and accelerated fractionation: Impact of chemotherapy schemes
    • Yau TK, Lee AW, Wong DH, et al. Treatment of stage IV(A-B) nasopharyngeal carcinoma by induction-concurrent chemoradiotherapy and accelerated fractionation: impact of chemotherapy schemes. Int J Radiat Oncol Biol Phys. 2006;66(4):1004-1010.
    • (2006) Int J Radiat Oncol Biol Phys , vol.66 , Issue.4 , pp. 1004-1010
    • Yau, T.K.1    Lee, A.W.2    Wong, D.H.3
  • 86
    • 15444347863 scopus 로고    scopus 로고
    • Preliminary report of the Asian-Oceanian Clinical Oncology Association randomized trial comparing cisplatin and epirubicin followed by radiotherapy versus radiotherapy alone in the treatment of patients with locoregionally advanced nasopharyngeal carcinoma. Asian-Oceanian Clinical Oncology Association Nasopharynx Cancer Study Group
    • Chua DT, Sham JS, Choy D, et al. Preliminary report of the Asian-Oceanian Clinical Oncology Association randomized trial comparing cisplatin and epirubicin followed by radiotherapy versus radiotherapy alone in the treatment of patients with locoregionally advanced nasopharyngeal carcinoma. Asian-Oceanian Clinical Oncology Association Nasopharynx Cancer Study Group. Cancer. 1998;83(11):2270-2283.
    • (1998) Cancer , vol.83 , Issue.11 , pp. 2270-2283
    • Chua, D.T.1    Sham, J.S.2    Choy, D.3
  • 87
    • 0037089673 scopus 로고    scopus 로고
    • A prospective, randomized trial comparing neoadjuvant chemotherapy with radiotherapy alone in patients with advanced nasopharyngeal carcinoma
    • Hareyama M, Sakata K, Shirato H, et al. A prospective, randomized trial comparing neoadjuvant chemotherapy with radiotherapy alone in patients with advanced nasopharyngeal carcinoma. Cancer. 2002;94(8):2217-2223.
    • (2002) Cancer , vol.94 , Issue.8 , pp. 2217-2223
    • Hareyama, M.1    Sakata, K.2    Shirato, H.3
  • 88
    • 0035282127 scopus 로고    scopus 로고
    • Results of a prospective randomized trial comparing neoadjuvant chemotherapy plus radiotherapy with radiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma
    • Ma J, Mai HQ, Hong MH, et al. Results of a prospective randomized trial comparing neoadjuvant chemotherapy plus radiotherapy with radiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma. J Clin Oncol. 2001;19(5):1350-1357.
    • (2001) J Clin Oncol , vol.19 , Issue.5 , pp. 1350-1357
    • Ma, J.1    Mai, H.Q.2    Hong, M.H.3
  • 89
    • 0344915699 scopus 로고    scopus 로고
    • Preliminary results of a randomized trial comparing neoadjuvant chemotherapy (cisplatin, epirubicin, bleomycin) plus radiotherapy vs radiotherapy alone in stage IV (. or = N2, M0) undifferentiated nasopharyngeal carcinoma: A positive effect on progression-free survival. International Nasopharynx Cancer Study Group. VUMCA I trial
    • Roussy IG. Preliminary results of a randomized trial comparing neoadjuvant chemotherapy (cisplatin, epirubicin, bleomycin) plus radiotherapy vs radiotherapy alone in stage IV (. or = N2, M0) undifferentiated nasopharyngeal carcinoma: a positive effect on progression-free survival. International Nasopharynx Cancer Study Group. VUMCA I trial. Int J Radiat Oncol Biol Phys. 1996;35(3):463-469.
    • (1996) Int J Radiat Oncol Biol Phys , vol.35 , Issue.3 , pp. 463-469
    • Roussy, I.G.1
  • 90
    • 0024274529 scopus 로고
    • Adjuvant chemotherapy with vincristine, cyclophosphamide, and doxorubicin after radiotherapy in local-regional nasopharyngeal cancer: Results of a 4-year multicenter randomized study
    • Rossi A, Molinari R, Boracchi P, et al. Adjuvant chemotherapy with vincristine, cyclophosphamide, and doxorubicin after radiotherapy in local-regional nasopharyngeal cancer: results of a 4-year multicenter randomized study. J Clin Oncol. 1988;6(9):1401-1410.
    • (1988) J Clin Oncol , vol.6 , Issue.9 , pp. 1401-1410
    • Rossi, A.1    Molinari, R.2    Boracchi, P.3
  • 91
    • 0028840284 scopus 로고
    • A prospective randomized study of chemotherapy adjunctive to definitive radiotherapy in advanced nasopharyngeal carcinoma
    • Chan AT, Teo PM, Leung TW, et al. A prospective randomized study of chemotherapy adjunctive to definitive radiotherapy in advanced nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 1995;33(3): 569-577.
    • (1995) Int J Radiat Oncol Biol Phys , vol.33 , Issue.3 , pp. 569-577
    • Chan, A.T.1    Teo, P.M.2    Leung, T.W.3
  • 92
    • 29244448683 scopus 로고    scopus 로고
    • Chemotherapy in locally advanced nasopharyngeal carcinoma: An individual patient data meta-analysis of eight randomized trials and 1753 patients
    • Baujat B, Audry H, Bourhis J, et al. Chemotherapy in locally advanced nasopharyngeal carcinoma: an individual patient data meta-analysis of eight randomized trials and 1753 patients. Int J Radiat Oncol Biol Phys. 2006;64(1):47-56.
    • (2006) Int J Radiat Oncol Biol Phys , vol.64 , Issue.1 , pp. 47-56
    • Baujat, B.1    Audry, H.2    Bourhis, J.3
  • 93
    • 77957924106 scopus 로고    scopus 로고
    • The role of concurrent chemoradiotherapy in the treatment of locoregionally advanced nasopharyngeal carcinoma among endemic population: A meta-analysis of the phase III randomized trials
    • Zhang L, Zhao C, Ghimire B, et al. The role of concurrent chemoradiotherapy in the treatment of locoregionally advanced nasopharyngeal carcinoma among endemic population: a meta-analysis of the phase III randomized trials. BMC Cancer. 2010;10:558.
    • (2010) BMC Cancer , vol.10 , pp. 558
    • Zhang, L.1    Zhao, C.2    Ghimire, B.3
  • 94
    • 84856438865 scopus 로고    scopus 로고
    • Concurrent chemoradiotherapy plus adjuvant chemotherapy versus concurrent chemoradiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma: A phase 3 multicentre randomised controlled trial
    • Chen L, Hu CS, Chen XZ, et al. Concurrent chemoradiotherapy plus adjuvant chemotherapy versus concurrent chemoradiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma: a phase 3 multicentre randomised controlled trial. Lancet Oncol. 2012;13(2):163-171.
    • (2012) Lancet Oncol , vol.13 , Issue.2 , pp. 163-171
    • Chen, L.1    Hu, C.S.2    Chen, X.Z.3
  • 95
    • 79952103326 scopus 로고    scopus 로고
    • Factors contributing to the efficacy of concurrent-adjuvant chemotherapy for locoregionally advanced nasopharyngeal carcinoma: Combined analyses of NPC-9901 and NPC-9902 Trials
    • Lee AW, Tung SY, Ngan RK, et al. Factors contributing to the efficacy of concurrent-adjuvant chemotherapy for locoregionally advanced nasopharyngeal carcinoma: combined analyses of NPC-9901 and NPC-9902 Trials. Eur J Cancer. 2011;47(5):656-666.
    • (2011) Eur J Cancer , vol.47 , Issue.5 , pp. 656-666
    • Lee, A.W.1    Tung, S.Y.2    Ngan, R.K.3
  • 97
    • 0032772169 scopus 로고    scopus 로고
    • Induction with mitomycin C, doxorubicin, cisplatin and maintenance with weekly 5-fluorouracil, leucovorin for treatment of metastatic nasopharyngeal carcinoma: A phase II study
    • Hong RL, Sheen TS, Ko JY, Hsu MM, Wang CC, Ting LL. Induction with mitomycin C, doxorubicin, cisplatin and maintenance with weekly 5-fluorouracil, leucovorin for treatment of metastatic nasopharyngeal carcinoma: a phase II study. Br J Cancer. 1999;80(12):1962-1967.
    • (1999) Br J Cancer , vol.80 , Issue.12 , pp. 1962-1967
    • Hong, R.L.1    Sheen, T.S.2    Ko, J.Y.3    Hsu, M.M.4    Wang, C.C.5    Ting, L.L.6
  • 98
    • 53149111132 scopus 로고    scopus 로고
    • Triplet combination of gemcitabine, paclitaxel, and carboplatin followed by maintenance 5-fluorouracil and folinic acid in patients with metastatic nasopharyngeal carcinoma
    • Leong SS, Wee J, Rajan S, et al. Triplet combination of gemcitabine, paclitaxel, and carboplatin followed by maintenance 5-fluorouracil and folinic acid in patients with metastatic nasopharyngeal carcinoma. Cancer. 2008;113(6):1332-1337.
    • (2008) Cancer , vol.113 , Issue.6 , pp. 1332-1337
    • Leong, S.S.1    Wee, J.2    Rajan, S.3
  • 99
    • 84867043925 scopus 로고    scopus 로고
    • If concurrent-adjuvant chemoradiotherapy is beneficial for locoregionally advanced nasopharyngeal carcinoma, would changing the sequence to induction-concurrent achieve better outcome?
    • Lee AWM, Ng WT, Chan OSH, Sze HCK. If concurrent-adjuvant chemoradiotherapy is beneficial for locoregionally advanced nasopharyngeal carcinoma, would changing the sequence to induction-concurrent achieve better outcome? J Radiat Oncol. 2012;1(2):107-115.
    • (2012) J Radiat Oncol , vol.1 , Issue.2 , pp. 107-115
    • Lee, A.W.M.1    Ng, W.T.2    Chan, O.S.H.3    Sze, H.C.K.4
  • 100
    • 43049175165 scopus 로고    scopus 로고
    • Potential improvement of tumor control probability by induction chemotherapy for advanced nasopharyngeal carcinoma
    • Lee AW, Lau KY, Hung WM, et al. Potential improvement of tumor control probability by induction chemotherapy for advanced nasopharyngeal carcinoma. Radiother Oncol. 2008;87(2):204-210.
    • (2008) Radiother Oncol , vol.87 , Issue.2 , pp. 204-210
    • Lee, A.W.1    Lau, K.Y.2    Hung, W.M.3
  • 101
    • 0036533894 scopus 로고    scopus 로고
    • Excellent disease control and survival in patients with advanced nasopharyngeal cancer treated with chemoradiation
    • Rischin D, Corry J, Smith J, Stewart J, Hughes P, Peters L. Excellent disease control and survival in patients with advanced nasopharyngeal cancer treated with chemoradiation. J Clin Oncol. 2002;20(7):1845-1852.
    • (2002) J Clin Oncol , vol.20 , Issue.7 , pp. 1845-1852
    • Rischin, D.1    Corry, J.2    Smith, J.3    Stewart, J.4    Hughes, P.5    Peters, L.6
  • 102
    • 58249089750 scopus 로고    scopus 로고
    • Randomized phase II trial of concurrent cisplatin-radiotherapy with or without neoadjuvant docetaxel and cisplatin in advanced nasopharyngeal carcinoma
    • Hui EP, Ma BB, Chan AT, et al. Randomized phase II trial of concurrent cisplatin-radiotherapy with or without neoadjuvant docetaxel and cisplatin in advanced nasopharyngeal carcinoma. J Clin Oncol. 2009;27(2):242-249.
    • (2009) J Clin Oncol , vol.27 , Issue.2 , pp. 242-249
    • Hui, E.P.1    Ma, B.B.2    Chan, A.T.3
  • 103
    • 84856316834 scopus 로고    scopus 로고
    • Induction chemotherapy followed by concomitant radiotherapy and weekly cisplatin versus the same concomitant chemoradiotherapy in patients with nasopharyngeal carcinoma: A randomized phase II study conducted by the Hellenic Cooperative Oncology Group (HeCOG) with biomarker evaluation
    • Fountzilas G, Ciuleanu E, Bobos M, et al. Induction chemotherapy followed by concomitant radiotherapy and weekly cisplatin versus the same concomitant chemoradiotherapy in patients with nasopharyngeal carcinoma: a randomized phase II study conducted by the Hellenic Cooperative Oncology Group (HeCOG) with biomarker evaluation. Ann Oncol. 2012;23(2):427-435.
    • (2012) Ann Oncol , vol.23 , Issue.2 , pp. 427-435
    • Fountzilas, G.1    Ciuleanu, E.2    Bobos, M.3
  • 104
    • 84866420451 scopus 로고    scopus 로고
    • A randomized trial of induction chemotherapy plus concurrent chemoradiotherapy versus induction chemotherapy plus radiotherapy for locoregionally advanced nasopharyngeal carcinoma
    • Huang PY, Cao KJ, Guo X, et al. A randomized trial of induction chemotherapy plus concurrent chemoradiotherapy versus induction chemotherapy plus radiotherapy for locoregionally advanced nasopharyngeal carcinoma. Oral Oncol. 2012;48(10):1038-1044.
    • (2012) Oral Oncol , vol.48 , Issue.10 , pp. 1038-1044
    • Huang, P.Y.1    Cao, K.J.2    Guo, X.3
  • 105
    • 33645841940 scopus 로고    scopus 로고
    • Treatment outcomes of patients with AJCC stage IVC nasopharyngeal carcinoma: Benefits of primary radiotherapy
    • Yeh SA, Tang Y, Lui CC, Huang EY. Treatment outcomes of patients with AJCC stage IVC nasopharyngeal carcinoma: benefits of primary radiotherapy. Jpn J Clin Oncol. 2006;36(3):132-136.
    • (2006) Jpn J Clin Oncol , vol.36 , Issue.3 , pp. 132-136
    • Yeh, S.A.1    Tang, Y.2    Lui, C.C.3    Huang, E.Y.4
  • 106
    • 84866714643 scopus 로고    scopus 로고
    • Combined high-dose radiation therapy and systemic chemotherapy improves survival in patients with newly diagnosed metastatic nasopharyngeal cancer
    • Lin S, Tham IW, Pan J, Han L, Chen Q, Lu JJ. Combined high-dose radiation therapy and systemic chemotherapy improves survival in patients with newly diagnosed metastatic nasopharyngeal cancer. Am J Clin Oncol. 2012;35(5):474-479.
    • (2012) Am J Clin Oncol , vol.35 , Issue.5 , pp. 474-479
    • Lin, S.1    Tham, I.W.2    Pan, J.3    Han, L.4    Chen, Q.5    Lu, J.J.6
  • 107
    • 84859764424 scopus 로고    scopus 로고
    • Definitive treatment of metastatic nasopharyngeal carcinoma: Report of 5 cases with review of literature
    • Setton J, Wolden S, Caria N, Lee N. Definitive treatment of metastatic nasopharyngeal carcinoma: report of 5 cases with review of literature. Head Neck. 2012;34(5):753-757.
    • (2012) Head Neck , vol.34 , Issue.5 , pp. 753-757
    • Setton, J.1    Wolden, S.2    Caria, N.3    Lee, N.4
  • 109
    • 84861098191 scopus 로고    scopus 로고
    • Intensity-modulated radiation therapy in the salvage of locally recurrent nasopharyngeal carcinoma
    • Qiu S, Lin S, Tham IW, Pan J, Lu J, Lu JJ. Intensity-modulated radiation therapy in the salvage of locally recurrent nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 2012;83(2):676-683.
    • (2012) Int J Radiat Oncol Biol Phys , vol.83 , Issue.2 , pp. 676-683
    • Qiu, S.1    Lin, S.2    Tham, I.W.3    Pan, J.4    Lu, J.5    Lu, J.J.6
  • 110
    • 77957964200 scopus 로고    scopus 로고
    • Comparison of single versus fractionated dose of stereotactic radiotherapy for salvaging local failures of nasopharyngeal carcinoma: A matched-cohort analysis
    • Chua DT, Wu SX, Lee V, Tsang J. Comparison of single versus fractionated dose of stereotactic radiotherapy for salvaging local failures of nasopharyngeal carcinoma: a matched-cohort analysis. Head Neck Oncol. 2009;1:13.
    • (2009) Head Neck Oncol , vol.1 , pp. 13
    • Chua, D.T.1    Wu, S.X.2    Lee, V.3    Tsang, J.4
  • 111
    • 79959199372 scopus 로고    scopus 로고
    • Surgical salvage of persistent or recurrent nasopharyngeal carcinoma with maxillary swing approach - critical appraisal after 2 decades
    • Wei WI, Chan JY, Ng RW, Ho WK. Surgical salvage of persistent or recurrent nasopharyngeal carcinoma with maxillary swing approach - critical appraisal after 2 decades. Head Neck. 2011;33(7):969-975.
    • (2011) Head Neck , vol.33 , Issue.7 , pp. 969-975
    • Wei, W.I.1    Chan, J.Y.2    Ng, R.W.3    Ho, W.K.4
  • 112
    • 64049106902 scopus 로고    scopus 로고
    • Endoscopic microwave coagulation therapy for early recurrent T1 nasopharyngeal carcinoma
    • Mai HQ, Mo HY, Deng JF, et al. Endoscopic microwave coagulation therapy for early recurrent T1 nasopharyngeal carcinoma. Eur J Cancer. 2009;45(7):1107-1110.
    • (2009) Eur J Cancer , vol.45 , Issue.7 , pp. 1107-1110
    • Mai, H.Q.1    Mo, H.Y.2    Deng, J.F.3
  • 113
    • 79953840298 scopus 로고    scopus 로고
    • Recurrent nasopharyngeal carcinoma: Surgical salvage vs additional chemoradiation
    • Wei WI, Kwong DL. Recurrent nasopharyngeal carcinoma: surgical salvage vs additional chemoradiation. Curr Opin Otolaryngol Head Neck Surg. 2011;19(2):82-86.
    • (2011) Curr Opin Otolaryngol Head Neck Surg , vol.19 , Issue.2 , pp. 82-86
    • Wei, W.I.1    Kwong, D.L.2
  • 114
    • 64849110423 scopus 로고    scopus 로고
    • Endoscopic nasopharyngectomy for locally recurrent nasopharyngeal carcinoma
    • Chen MY, Wen WP, Guo X, et al. Endoscopic nasopharyngectomy for locally recurrent nasopharyngeal carcinoma. Laryngoscope. 2009;119(3):516-522.
    • (2009) Laryngoscope , vol.119 , Issue.3 , pp. 516-522
    • Chen, M.Y.1    Wen, W.P.2    Guo, X.3
  • 116
    • 84869500948 scopus 로고    scopus 로고
    • Long-term treatment outcome of recurrent nasopharyngeal carcinoma treated with salvage intensity modulated radiotherapy
    • Hua YJ, Han F, Lu LX, et al. Long-term treatment outcome of recurrent nasopharyngeal carcinoma treated with salvage intensity modulated radiotherapy. Eur J Cancer. 2012;48(18):3422-3428.
    • (2012) Eur J Cancer , vol.48 , Issue.18 , pp. 3422-3428
    • Hua, Y.J.1    Han, F.2    Lu, L.X.3
  • 117
    • 0025145058 scopus 로고
    • Efficacy of radical neck dissection for the control of cervical metastasis after radiotherapy for nasopharyngeal carcinoma
    • Wei WI, Lam KH, Ho CM, Sham JS, Lau SK. Efficacy of radical neck dissection for the control of cervical metastasis after radiotherapy for nasopharyngeal carcinoma. Am J Surg. 1990;160(4):439-442.
    • (1990) Am J Surg , vol.160 , Issue.4 , pp. 439-442
    • Wei, W.I.1    Lam, K.H.2    Ho, C.M.3    Sham, J.S.4    Lau, S.K.5
  • 118
    • 78651365779 scopus 로고    scopus 로고
    • Salvage surgery for neck residue or recurrence of nasopharyngeal carcinoma: A 10-year experience
    • Zhang L, Zhu YX, Wang Y, Huang CP, Wu Y, Ji QH. Salvage surgery for neck residue or recurrence of nasopharyngeal carcinoma: a 10-year experience. Ann Surg Oncol. 2011;18(1):233-238.
    • (2011) Ann Surg Oncol , vol.18 , Issue.1 , pp. 233-238
    • Zhang, L.1    Zhu, Y.X.2    Wang, Y.3    Huang, C.P.4    Wu, Y.5    Ji, Q.H.6
  • 119
    • 77955097287 scopus 로고    scopus 로고
    • Is it necessary to perform radical neck dissection as a salvage procedure for persistent or recurrent neck disease after chemoradiotherapy in patients with nasopharyngeal cancer?
    • Khafif A, Ferlito A, Takes RP, Thomas Robbins K. Is it necessary to perform radical neck dissection as a salvage procedure for persistent or recurrent neck disease after chemoradiotherapy in patients with nasopharyngeal cancer? Eur Arch Otorhinolaryngol. 2010;267(7): 997-999.
    • (2010) Eur Arch Otorhinolaryngol , vol.267 , Issue.7 , pp. 997-999
    • Khafif, A.1    Ferlito, A.2    Takes, R.P.3    Thomas, R.K.4
  • 120
    • 84862252904 scopus 로고    scopus 로고
    • Salvage treatment for isolated regional failure of nasopharyngeal carcinoma after primary radiotherapy
    • Lo WC, Wang CP, Ko JY, et al. Salvage treatment for isolated regional failure of nasopharyngeal carcinoma after primary radiotherapy. Ann Surg Oncol. 2012;19(3):1001-1008.
    • (2012) Ann Surg Oncol , vol.19 , Issue.3 , pp. 1001-1008
    • Lo, W.C.1    Wang, C.P.2    Ko, J.Y.3
  • 121
    • 4644345181 scopus 로고    scopus 로고
    • Prognostic value of epidermal growth factor receptor expression in patients with advanced stage nasopharyngeal carcinoma treated with induction chemotherapy and radiotherapy
    • Chua DT, Nicholls JM, Sham JS, et al. Prognostic value of epidermal growth factor receptor expression in patients with advanced stage nasopharyngeal carcinoma treated with induction chemotherapy and radiotherapy. Int J Radiat Oncol Biol Phys. 2004;62(1): 11-20.
    • (2004) Int J Radiat Oncol Biol Phys , vol.62 , Issue.1 , pp. 11-20
    • Chua, D.T.1    Nicholls, J.M.2    Sham, J.S.3
  • 122
    • 20644435370 scopus 로고    scopus 로고
    • Multicenter, phase III study of cetuximab in combination with carboplatin in patients with recurrent or metastatic nasopharyngeal carcinoma
    • Chan AT, Hsu MM, Goh BC, et al. Multicenter, phase III study of cetuximab in combination with carboplatin in patients with recurrent or metastatic nasopharyngeal carcinoma. J Clin Oncol. 2005;23(15):3568-3576.
    • (2005) J Clin Oncol , vol.23 , Issue.15 , pp. 3568-3576
    • Chan, A.T.1    Hsu, M.M.2    Goh, B.C.3
  • 123
    • 47549095907 scopus 로고    scopus 로고
    • Phase II study of gefitinib for the treatment of recurrent and metastatic nasopharyngeal carcinoma
    • Chua DT, Wei WI, Wong MP, Sham JS, Nicholls J, Au GK. Phase II study of gefitinib for the treatment of recurrent and metastatic nasopharyngeal carcinoma. Head Neck. 2008;30(7):863-867.
    • (2008) Head Neck , vol.30 , Issue.7 , pp. 863-867
    • Chua, D.T.1    Wei, W.I.2    Wong, M.P.3    Sham, J.S.4    Nicholls, J.5    Au, G.K.6
  • 124
    • 42149109105 scopus 로고    scopus 로고
    • A phase II study of patients with metastatic or locoregionally recurrent nasopharyngeal carcinoma and evaluation of plasma Epstein-Barr virus DNA as a biomarker of efficacy
    • Ma B, Hui EP, King A, et al. A phase II study of patients with metastatic or locoregionally recurrent nasopharyngeal carcinoma and evaluation of plasma Epstein-Barr virus DNA as a biomarker of efficacy. Cancer Chemother Pharmacol. 2008;62(1):59-64.
    • (2008) Cancer Chemother Pharmacol , vol.62 , Issue.1 , pp. 59-64
    • Ma, B.1    Hui, E.P.2    King, A.3
  • 125
    • 84892808887 scopus 로고    scopus 로고
    • An open-labeled, multicentric clinical study of cetuximab combined with intensity-modulated radiotherapy (IMRT) plus concurrent chemotherapy in locoregionally advanced (LA) nasopharyngeal carcinoma (NPC): A 2-year follow-up report. 2012 ASCO Annal Meeting
    • Chen CY, Zhao C, Gao L, et al. An open-labeled, multicentric clinical study of cetuximab combined with intensity-modulated radiotherapy (IMRT) plus concurrent chemotherapy in locoregionally advanced (LA) nasopharyngeal carcinoma (NPC): a 2-year follow-up report. 2012 ASCO Annal Meeting. J Clin Oncol. 2012; 30 Suppl:5535.
    • (2012) J Clin Oncol , vol.30 , Issue.SUPPL. , pp. 5535
    • Chen, C.Y.1    Zhao, C.2    Gao, L.3
  • 126
    • 0033636382 scopus 로고    scopus 로고
    • The relationship between microvessel density, the expression of vascular endothelial growth factor (VEGF), and the extension of nasopharyngeal carcinoma
    • Guang-Wu H, Sunagawa M, Jie-En L, et al. The relationship between microvessel density, the expression of vascular endothelial growth factor (VEGF), and the extension of nasopharyngeal carcinoma. Laryngoscope. 2000;110(12):2066-2069.
    • (2000) Laryngoscope , vol.110 , Issue.12 , pp. 2066-2069
    • Guang-Wu, H.1    Sunagawa, M.2    Jie-En, L.3
  • 127
    • 0032914466 scopus 로고    scopus 로고
    • Association of vascular endothelial growth factor expression with angiogenesis and lymph node metastasis in nasopharyngeal carcinoma
    • Wakisaka N, Wen QH, Yoshizaki T, et al. Association of vascular endothelial growth factor expression with angiogenesis and lymph node metastasis in nasopharyngeal carcinoma. Laryngoscope. 1999;109(5):810-814.
    • (1999) Laryngoscope , vol.109 , Issue.5 , pp. 810-814
    • Wakisaka, N.1    Wen, Q.H.2    Yoshizaki, T.3
  • 128
    • 79957852682 scopus 로고    scopus 로고
    • Hemorrhagic complications in a phase II study of sunitinib in patients of nasopharyngeal carcinoma who has previously received high-dose radiation
    • Hui EP, Ma BB, King AD, et al. Hemorrhagic complications in a phase II study of sunitinib in patients of nasopharyngeal carcinoma who has previously received high-dose radiation. Ann Oncol. 2011; 22(6):1280-1287.
    • (2011) Ann Oncol , vol.22 , Issue.6 , pp. 1280-1287
    • Hui, E.P.1    Ma, B.B.2    King, A.D.3
  • 129
    • 1042301963 scopus 로고    scopus 로고
    • Epstein-Barr virus and cancer
    • Thompson MP, Kurzrock R. Epstein-Barr virus and cancer. Clin Cancer Res. 2004;10(3):803-821.
    • (2004) Clin Cancer Res , vol.10 , Issue.3 , pp. 803-821
    • Thompson, M.P.1    Kurzrock, R.2
  • 130
    • 34548448890 scopus 로고    scopus 로고
    • Epstein-Barr virus-targeted immunotherapy for nasopharyngeal carcinoma
    • Masmoudi A, Toumi N, Khanfir A, et al. Epstein-Barr virus-targeted immunotherapy for nasopharyngeal carcinoma. Cancer Treat Rev. 2007;33(6):499-505.
    • (2007) Cancer Treat Rev , vol.33 , Issue.6 , pp. 499-505
    • Masmoudi, A.1    Toumi, N.2    Khanfir, A.3
  • 132
    • 17944381522 scopus 로고    scopus 로고
    • Adoptive transfer of autologous Epstein-Barr virus-specific cytotoxic T cells for nasopharyngeal carcinoma
    • Chua D, Huang J, Zheng B, et al. Adoptive transfer of autologous Epstein-Barr virus-specific cytotoxic T cells for nasopharyngeal carcinoma. Int J Cancer. 2001;94(1):73-80.
    • (2001) Int J Cancer , vol.94 , Issue.1 , pp. 73-80
    • Chua, D.1    Huang, J.2    Zheng, B.3
  • 133
    • 33644788176 scopus 로고    scopus 로고
    • Cell therapy of stage IV nasopharyngeal carcinoma with autologous Epstein-Barr virus-targeted cytotoxic T lymphocytes
    • Comoli P, Pedrazzoli P, Maccario R, et al. Cell therapy of stage IV nasopharyngeal carcinoma with autologous Epstein-Barr virus-targeted cytotoxic T lymphocytes. J Clin Oncol. 2005;23(35): 8942-8949.
    • (2005) J Clin Oncol , vol.23 , Issue.35 , pp. 8942-8949
    • Comoli, P.1    Pedrazzoli, P.2    Maccario, R.3
  • 134
    • 20144365643 scopus 로고    scopus 로고
    • Treatment of nasopharyngeal carcinoma with Epstein-Barr virus-specific T lymphocytes
    • Straathof KC, Bollard CM, Popat U, et al. Treatment of nasopharyngeal carcinoma with Epstein-Barr virus-specific T lymphocytes. Blood. 2005;105(5):1898-1904.
    • (2005) Blood , vol.105 , Issue.5 , pp. 1898-1904
    • Straathof, K.C.1    Bollard, C.M.2    Popat, U.3
  • 135
    • 78149280601 scopus 로고    scopus 로고
    • Adoptive transfer of EBV-specific T cells results in sustained clinical responses in patients with locoregional nasopharyngeal carcinoma
    • Louis CU, Straathof K, Bollard CM, et al. Adoptive transfer of EBV-specific T cells results in sustained clinical responses in patients with locoregional nasopharyngeal carcinoma. J Immunother. 2010;33(9):983-990.
    • (2010) J Immunother , vol.33 , Issue.9 , pp. 983-990
    • Louis, C.U.1    Straathof, K.2    Bollard, C.M.3
  • 136
    • 0026594257 scopus 로고
    • Epstein-Barr virus latent gene transcription in nasopharyngeal carcinoma cells: Coexpression of EBNA1, LMP1, and LMP2 transcripts
    • Brooks L, Yao QY, Rickinson AB, Young LS. Epstein-Barr virus latent gene transcription in nasopharyngeal carcinoma cells: coexpression of EBNA1, LMP1, and LMP2 transcripts. J Virol. 1992;66(5): 2689-2697.
    • (1992) J Virol , vol.66 , Issue.5 , pp. 2689-2697
    • Brooks, L.1    Yao, Q.Y.2    Rickinson, A.B.3    Young, L.S.4
  • 137
    • 0023881404 scopus 로고
    • Epstein-Barr virus gene expression in nasopharyngeal carcinoma
    • Young LS, Dawson CW, Clark D, et al. Epstein-Barr virus gene expression in nasopharyngeal carcinoma. J Gen Virol. 1988;69(Pt 5): 1051-1065.
    • (1988) J Gen Virol , vol.69 , Issue.PART 5 , pp. 1051-1065
    • Young, L.S.1    Dawson, C.W.2    Clark, D.3
  • 138
    • 84859492195 scopus 로고    scopus 로고
    • A phase II study evaluating the safety and efficacy of an adenovirus-ΔLMP1-LMP2 transduced dendritic cell vaccine in patients with advanced metastatic nasopharyngeal carcinoma
    • Chia WK, Wang WW, Teo M, et al. A phase II study evaluating the safety and efficacy of an adenovirus-ΔLMP1-LMP2 transduced dendritic cell vaccine in patients with advanced metastatic nasopharyngeal carcinoma. Ann Oncol. 2012;23(4):997-1005.
    • (2012) Ann Oncol , vol.23 , Issue.4 , pp. 997-1005
    • Chia, W.K.1    Wang, W.W.2    Teo, M.3
  • 139
    • 9144270460 scopus 로고    scopus 로고
    • Adoptive transfer of allogeneic Epstein-Barr virus (EBV)-specific cytotoxic T cells with in vitro antitumor activity boosts LMP2-specific immune response in a patient with EBV-related nasopharyngeal carcinoma
    • Comoli P, De Palma R, Siena S, et al. Adoptive transfer of allogeneic Epstein-Barr virus (EBV)-specific cytotoxic T cells with in vitro antitumor activity boosts LMP2-specific immune response in a patient with EBV-related nasopharyngeal carcinoma. Ann Oncol. 2004;15(1): 113-117.
    • (2004) Ann Oncol , vol.15 , Issue.1 , pp. 113-117
    • Comoli, P.1    de Palma, R.2    Siena, S.3
  • 140
    • 0348230938 scopus 로고    scopus 로고
    • Dual stimulation of Epstein-Barr virus (EBV)-specific CD4+- and CD8+-T-cell responses by a chimeric antigen construct: Potential therapeutic vaccine for EBV-positive nasopharyngeal carcinoma
    • Taylor GS, Haigh TA, Gudgeon NH, et al. Dual stimulation of Epstein-Barr virus (EBV)-specific CD4+- and CD8+-T-cell responses by a chimeric antigen construct: potential therapeutic vaccine for EBV-positive nasopharyngeal carcinoma. J Virol. 2004;78(2):768-778.
    • (2004) J Virol , vol.78 , Issue.2 , pp. 768-778
    • Taylor, G.S.1    Haigh, T.A.2    Gudgeon, N.H.3
  • 141
    • 0038460251 scopus 로고    scopus 로고
    • Therapeutic LMP1 polyepitope vaccine for EBV-associated Hodgkin disease and nasopharyngeal carcinoma
    • Duraiswamy J, Sherritt M, Thomson S, et al. Therapeutic LMP1 polyepitope vaccine for EBV-associated Hodgkin disease and nasopharyngeal carcinoma. Blood. 2003;101(8):3150-3156.
    • (2003) Blood , vol.101 , Issue.8 , pp. 3150-3156
    • Duraiswamy, J.1    Sherritt, M.2    Thomson, S.3
  • 142
    • 1242293637 scopus 로고    scopus 로고
    • Induction of therapeutic T-cell responses to subdominant tumor-associated viral oncogene after immunization with replication-incompetent polyepitope adenovirus vaccine
    • Duraiswamy J, Bharadwaj M, Tellam J, et al. Induction of therapeutic T-cell responses to subdominant tumor-associated viral oncogene after immunization with replication-incompetent polyepitope adenovirus vaccine. Cancer Res. 2004;64(4):1483-1489.
    • (2004) Cancer Res , vol.64 , Issue.4 , pp. 1483-1489
    • Duraiswamy, J.1    Bharadwaj, M.2    Tellam, J.3
  • 143
    • 3042549658 scopus 로고    scopus 로고
    • The generation and characterization of LMP2-specific CTLs for use as adoptive transfer from patients with relapsed EBV-positive Hodgkin disease
    • Bollard CM, Straathof KC, Huls MH, et al. The generation and characterization of LMP2-specific CTLs for use as adoptive transfer from patients with relapsed EBV-positive Hodgkin disease. J Immunother. 2004;27(4):317-327.
    • (2004) J Immunother , vol.27 , Issue.4 , pp. 317-327
    • Bollard, C.M.1    Straathof, K.C.2    Huls, M.H.3
  • 144
    • 84863269918 scopus 로고    scopus 로고
    • Effective treatment of metastatic forms of Epstein-Barr virus-associated nasopharyngeal carcinoma with a novel adenovirus-based adoptive immunotherapy
    • Smith C, Tsang J, Beagley L, et al. Effective treatment of metastatic forms of Epstein-Barr virus-associated nasopharyngeal carcinoma with a novel adenovirus-based adoptive immunotherapy. Cancer Res. 2012;72(5):1116-1125.
    • (2012) Cancer Res , vol.72 , Issue.5 , pp. 1116-1125
    • Smith, C.1    Tsang, J.2    Beagley, L.3
  • 145
    • 40749154787 scopus 로고    scopus 로고
    • Intensity-modulated radiotherapy of nasopharyngeal carcinoma: A comparative treatment planning study of photons and protons
    • Taheri-Kadkhoda Z, Björk-Eriksson T, Nill S, et al. Intensity-modulated radiotherapy of nasopharyngeal carcinoma: a comparative treatment planning study of photons and protons. Radiat Oncol. 2008;3:4.
    • (2008) Radiat Oncol , vol.3 , pp. 4
    • Taheri-Kadkhoda, Z.1    Björk-Eriksson, T.2    Nill, S.3
  • 146
    • 51449090189 scopus 로고    scopus 로고
    • Intensity-modulated proton therapy versus helical tomotherapy in nasopharynx cancer: Planning comparison and NTCP evaluation
    • Widesott L, Pierelli A, Fiorino C, et al. Intensity-modulated proton therapy versus helical tomotherapy in nasopharynx cancer: planning comparison and NTCP evaluation. Int J Radiat Oncol Biol Phys. 2008;72(2):589-596.
    • (2008) Int J Radiat Oncol Biol Phys , vol.72 , Issue.2 , pp. 589-596
    • Widesott, L.1    Pierelli, A.2    Fiorino, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.