Whole-Field Simultaneous Integrated-Boost Intensity-Modulated Radiotherapy for Patients With Nasopharyngeal Carcinoma

International Journal of Radiation Oncology Biology Physics

Volumn 76, Issue 1, 2010, Pages 138-145

  Wong, Frank C S ^a   Ng, Alice W Y ^a   Lee, Victor H F ^b   Lui, Collin M M ^a   Yuen, Kwok Keung ^a   Sze, Wing Kin ^a   Leung, To Wai ^b   Tung, Stewart Y ^a  

^a TUEN MUN HOSPITAL   (Hong Kong)

^b QUEEN MARY HOSPITAL   (Hong Kong)

Author keywords

intensity modulated radiotherapy; Nasopharyngeal carcinoma; treatment results

Indexed keywords

BRACHYTHERAPY; CONFORMAL TREATMENT; COX REGRESSION ANALYSIS; FAILURE-FREE SURVIVAL; INTENSITY-MODULATED RADIOTHERAPY; LOCAL FAILURE; LOCOREGIONAL CONTROL; NASOPHARYNGEAL CARCINOMA; OVERALL SURVIVAL; OVERALL SURVIVAL RATES; PLANNING TARGET VOLUMES; REGIONAL FAILURES; UP PERIOD; WORLD HEALTH ORGANIZATION;

CHEMOTHERAPY; HEALTH RISKS; PATIENT MONITORING; REGRESSION ANALYSIS;

RADIOTHERAPY;

CISPLATIN; FLUOROURACIL;

ADULT; AGED; ARTICLE; BRACHYTHERAPY; CANCER ADJUVANT THERAPY; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; INTENSITY MODULATED RADIATION THERAPY; MAJOR CLINICAL STUDY; MALE; MUCOSA INFLAMMATION; MULTIPLE CYCLE TREATMENT; NASOPHARYNX CARCINOMA; PHARYNGITIS; PRIORITY JOURNAL; RADIATION DOSE; RADIATION DOSE FRACTIONATION; RADIATION INJURY; TREATMENT DURATION; TREATMENT FAILURE; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; BRACHYTHERAPY; DISEASE-FREE SURVIVAL; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; MUCOSITIS; NASOPHARYNGEAL NEOPLASMS; NEOPLASM STAGING; PHARYNGITIS; RADIOTHERAPY DOSAGE; RADIOTHERAPY, INTENSITY-MODULATED; REGRESSION ANALYSIS; REMISSION INDUCTION; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; TUMOR BURDEN; YOUNG ADULT;

EID: 72049091457     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.01.084     Document Type: Article

References (26)

1. Leung T.W., Tung S.Y., Sze W.K., et al. Treatment results of 1070 patients with nasopharyngeal carcinoma: An analysis of survival and failure patterns. Head Neck 27 (2005) 555-565
2. Lee A.W.M., Sze W.M., Au J.S.K., et al. Treatment results for nasopharyngeal carcinoma in the modern era: the Hong Kong experience. Int J Radiat Oncol Biol Phys 61 (2005) 1107-1116
3. Leung T.W., Wong V.Y.W., Sze W.K., et al. High-dose-rate intracavitary brachytherapy boost for early T stage nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys 70 (2008) 361-367
4. Chen H.H.W., Tsai S.T., Wang M.S., et al. Experience in fractionated stereotactic body radiation therapy boost for newly diagnosed nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys 66 (2006) 1408-1414
5. Chau R.M.C., Teo P.M.L., Choi P.H.K., et al. Three-dimensional dosimetric evaluation of a conventional radiotherapy technique for treatment of nasopharyngeal carcinoma. Radiother Oncol 58 (2001) 143-153
6. Teo M.L., Ma B.Y., and Chan A.T.C. Radiotherapy for nasopharyngeal carcinoma-Transition from two-dimensional to three-dimensional methods. Radiother Oncol 73 (2004) 163-172
7. Lee A.W.M., Tung S.Y., Chan A.T.C., et al. Preliminary results of a randomised study (NPC-9902 trial) on therapeutic gain by concurrent chemotherapy and/or accelerated fractionation for locally advanced nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys 66 (2006) 142-151
8. Lee A.W.M., Lau W.H., Tung S.Y., et al. Preliminary results of a randomized study on therapeutic gain by concurrent chemotherapy for regionally-advanced nasopharyngeal carcinoma: NPC-9901 trial by the Hong Kong Nasopharyngeal Cancer Study Group. J Clin Oncol 23 (2005) 6966-6975
9. Al-Sarraf M., LeBlanc M., Giri P.G., et al. Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: Phase III randomised intergroup study 0099. J Clin Oncol 16 (1998) 1310-1317
10. Baujat B., Audry H., Bourhis J., et al. Chemotherapy in locally advanced nasopharyngeal carcinoma: An individual patient data meta-analysis of eight randomised trials and 1753 patients. Int J Radiat Oncol Biol Phys 64 (2006) 47-56
11. Kam M.M.K., Teo P.M., Chau R.M., et al. Treatment of nasopharyngeal carcinoma with intensity-modulated radiotherapy: The Hong Kong experience. Int J Radiat Oncol Biol Phys 60 (2004) 1440-1450
12. Kwong D.L., Sham J.S.T., Leung L.H., et al. Preliminary results of radiation dose escalation for locally advanced nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys 64 (2006) 374-381
13. Lee N., Xia P., Quiey J.M., et al. Intensity-modulated radiotherapy in the treatment of nasopharyngeal carcinoma: An update of the UCSF experience. Int J Radiat Oncol Biol Phys 53 (2002) 12-22
14. Wolden S.L., Chen W.C., Pfister D.G., et al. Intensity-modulated radiation therapy (IMRT) for nasopharynx cancer: Update of the Memorial Sloan-Kettering experience. Int J Radiat Oncol Biol Phys 64 (2006) 57-62
15. Lee S.W., Back G.M., Yi B.Y., et al. Preliminary results of a phase I/II study of simultaneous modulated accelerated radiotherapy for nondisseminated nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys 65 (2006) 252-160
16. Wu S., Xie C., Jin X., et al. Simultaneous modulated accelerated radiation therapy in the treatment of nasopharyngeal cancer: A local center's experience. Int J Radiat Oncol Biol Phys 66 (2006) S40-S46
17. Chen S.W., Yang S.N., Liang J.A., et al. Comparative dosimetric study of two strategies of intensity-modulated radiotherapy in nasopharyngeal cancer. Med Dosim 30 (2005) 219-227
18. Lee N., Mechalakos J., Puri D.R., et al. Choosing an intensity-modulated radiation therapy technique in the treatment of head-and neck cancer. Int J Radiat Oncol Biol Phys 68 (2007) 1299-1309
19. Amdur R.J., Liu C., Li J., et al. Matching intensity-modulated radiation therapy to an anterior low neck field. Int J Radiat Oncol Biol Phys 69 (2007) S46-S48
20. Fua T.F., Corry J., Milner A.D., et al. Intensity-modulated radiotherapy for nasopharyngeal carcinoma: Clinical correlation of dose to the pharyngo-esophageal axis and dysphagia. Int J Radiat Oncol Biol Phys 67 (2007) 976-981
21. American Joint Committee on Cancer. Manual for staging of cancer. 5th ed (1997), JB Lippincott, Philadelphia
22. Lee N.Y., Harris J., Garden A., et al. Phase II multi-institutional study of IMRT +/- chemotherapy for NPC (RTOG 0225): Preliminary results. Int J Radiat Oncol Biol Phys 69 (2007) S13-S14
23. Trotti A., Colevas D., Setser A., et al. CTCAE v3.0: Development of a comprehensive grading system for the adverse effects of cancer treatment. Semin Radiat Oncol 13 (2003) 176-181
24. Ng W.T., Chan S.H., Lee A.W.M., et al. Parapharyngeal extension of nasopharyngeal carcinoma: Still a significant factor in era of modern radiotherapy?. Int J Radiat Oncol Biol Phys 72 (2008) 1082-1089
25. Sze W.M., Lee A.W.M., Yau T.K., et al. Primary tumour volume of nasopharyngeal carcinoma: prognostic significance for local control. Int J Radiat Oncol Biol Phys 59 (2004) 21-27
26. Teo P.M.L., Leung S.F., Tung S.Y., et al. Dose-response relationship of nasopharyngeal carcinoma above conventional tumoricidal level: a study by the Hong Kong nasopharyngeal carcinoma study group (HKNPCSG). Radiother Oncol 79 (2006) 27-33