Correlation between molecular mobility and physical stability of amorphous itraconazole

Molecular Pharmaceutics

Volumn 10, Issue 2, 2013, Pages 694-700

  Bhardwaj, Sunny P ^a,b   Arora, Kapildev K ^a,c   Kwong, Elizabeth ^b,d   Templeton, Allen ^b   Clas, Sophie Dorothee ^b   Suryanarayanan, Raj ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^d Kwong Eureka Solutions   (Canada)

Author keywords

amorphous; crystallization kinetics; crystallization onset; dielectric spectroscopy; itraconazole; molecular mobility

Indexed keywords

ITRACONAZOLE;

ARTICLE; CHEMICAL PARAMETERS; CRYSTALLIZATION; DRUG SOLUBILITY; DRUG STABILITY; ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY; KINETICS; MOLECULAR DYNAMICS; MOLECULAR MOBILITY; PRIORITY JOURNAL; TEMPERATURE DEPENDENCE; THERMOGRAVIMETRY; X RAY DIFFRACTION;

CRYSTALLIZATION; ITRACONAZOLE; KINETICS;

EID: 84873373553     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300487u     Document Type: Article

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