메뉴 건너뛰기




Volumn 32, Issue 4, 2012, Pages 298-306

Using human-induced pluripotent stem cells to model monogenic metabolic disorders of the liver

Author keywords

cell transplantation; disease modeling; hepatocyte differentiation; human induced pluripotent stem cells; inherited liver metabolic disorders

Indexed keywords

ALPHA 1 ANTITRYPSIN;

EID: 84873362963     PISSN: 02728087     EISSN: 10988971     Source Type: Journal    
DOI: 10.1055/s-0032-1329898     Document Type: Article
Times cited : (16)

References (104)
  • 3
    • 77953400851 scopus 로고    scopus 로고
    • Tissue-level modeling of xenobiotic metabolism in liver: An emerging tool for enabling clinical translational research
    • Lerapetritou M. G., Georgopoulos P. G., Roth C. M., Androulakis L. P. Tissue-level modeling of xenobiotic metabolism in liver: An emerging tool for enabling clinical translational research. Clin Transl Sci: 2009; 2 3 228 237
    • (2009) Clin Transl Sci , vol.2 , Issue.3 , pp. 228-237
    • Lerapetritou, M.G.1    Georgopoulos, P.G.2    Roth, C.M.3    Androulakis, L.P.4
  • 4
    • 33646893457 scopus 로고    scopus 로고
    • Inborn errors of metabolism: The flux from Mendelian to complex diseases
    • DOI 10.1038/nrg1880, PII N1880
    • Lanpher B., Brunetti-Pierri N., Lee B. Inborn errors of metabolism: the flux from Mendelian to complex diseases. Nat Rev Genet: 2006; 7 6 449 460 (Pubitemid 43780488)
    • (2006) Nature Reviews Genetics , vol.7 , Issue.6 , pp. 449-460
    • Lanpher, B.1    Brunetti-Pierri, N.2    Lee, B.3
  • 5
    • 74249085690 scopus 로고    scopus 로고
    • Genome-wide association studies-A summary for the clinical gastroenterologist
    • Melum E., Franke A., Karlsen T. H. Genome-wide association studies-a summary for the clinical gastroenterologist. World J Gastroenterol: 2009; 15 43 5377 5396
    • (2009) World J Gastroenterol , vol.15 , Issue.43 , pp. 5377-5396
    • Melum, E.1    Franke, A.2    Karlsen, T.H.3
  • 6
    • 84858640258 scopus 로고    scopus 로고
    • Inborn errors of metabolism: Psychosocial challenges and proposed family systems model of intervention
    • Weber S. L., Segal S., Packman W. Inborn errors of metabolism: psychosocial challenges and proposed family systems model of intervention. Mol Genet Metab: 2012; 105 4 537 541
    • (2012) Mol Genet Metab , vol.105 , Issue.4 , pp. 537-541
    • Weber, S.L.1    Segal, S.2    Packman, W.3
  • 7
    • 33745088113 scopus 로고    scopus 로고
    • Liver transplantation for inborn errors of liver metabolism
    • DOI 10.1007/s10545-006-0288-x
    • Sokal E. M. Liver transplantation for inborn errors of liver metabolism. J Inherit Metab Dis: 2006; 29 2-3 426 430 (Pubitemid 43880646)
    • (2006) Journal of Inherited Metabolic Disease , vol.29 , Issue.2-3 , pp. 426-430
    • Sokal, E.M.1
  • 8
    • 43149087080 scopus 로고    scopus 로고
    • Liver cell transplantation for the treatment of inborn errors of metabolism
    • Meyburg J., Hoffmann G. F. Liver cell transplantation for the treatment of inborn errors of metabolism. J Inherit Metab Dis: 2008; 31 164 172
    • (2008) J Inherit Metab Dis , vol.31 , pp. 164-172
    • Meyburg, J.1    Hoffmann, G.F.2
  • 9
    • 56549117448 scopus 로고    scopus 로고
    • Animal models of NASH: Getting both pathology and metabolic context right
    • Larter C. Z., Yeh M. M. Animal models of NASH: getting both pathology and metabolic context right. J Gastroenterol Hepatol: 2008; 23 11 1635 1648
    • (2008) J Gastroenterol Hepatol , vol.23 , Issue.11 , pp. 1635-1648
    • Larter, C.Z.1    Yeh, M.M.2
  • 10
    • 77950679333 scopus 로고    scopus 로고
    • Can animal models of disease reliably inform human studies
    • van der Worp H. B., Howells D. W., Sena E. S., et al. Can animal models of disease reliably inform human studies? PLoS Med: 2010; 7 3 e1000245
    • (2010) PLoS Med , vol.7 , Issue.3
    • Van Der Worp, H.B.1    Howells, D.W.2    Sena, E.S.3
  • 11
    • 69249208658 scopus 로고    scopus 로고
    • Pluripotent stem cells and disease modeling
    • Colman A., Dreesen O. Pluripotent stem cells and disease modeling. Cell Stem Cell: 2009; 5 3 244 247
    • (2009) Cell Stem Cell , vol.5 , Issue.3 , pp. 244-247
    • Colman, A.1    Dreesen, O.2
  • 12
    • 78149320656 scopus 로고    scopus 로고
    • The benefits and limitations of animal models for translational research in neurodegenerative diseases
    • Jucker M. The benefits and limitations of animal models for translational research in neurodegenerative diseases. Nat Med: 2010; 16 11 1210 1214
    • (2010) Nat Med , vol.16 , Issue.11 , pp. 1210-1214
    • Jucker, M.1
  • 13
    • 0036303818 scopus 로고    scopus 로고
    • Genetically engineered mouse models of neurodegenerative diseases
    • DOI 10.1038/nn0702-633
    • Wong P. C., Cai H., Borchelt D. R., Price D. L. Genetically engineered mouse models of neurodegenerative diseases. Nat Neurosci: 2002; 5 7 633 639 (Pubitemid 34742978)
    • (2002) Nature Neuroscience , vol.5 , Issue.7 , pp. 633-639
    • Wong, P.C.1    Cai, H.2    Borchelt, D.R.3    Price, D.L.4
  • 14
    • 77953666105 scopus 로고    scopus 로고
    • Genetic animal models of Parkinson's disease
    • Dawson T. M., Ko H. S., Dawson V. L. Genetic animal models of Parkinson's disease. Neuron: 2010; 66 5 646 661
    • (2010) Neuron , vol.66 , Issue.5 , pp. 646-661
    • Dawson, T.M.1    Ko, H.S.2    Dawson, V.L.3
  • 15
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • DOI 10.1016/j.cell.2006.07.024, PII S0092867406009767
    • Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell: 2006; 126 4 663 676 (Pubitemid 44233629)
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 16
    • 36248966518 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
    • DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
    • Takahashi K., Tanabe K., Ohnuki M., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell: 2007; 131 5 861 872 (Pubitemid 350138099)
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 17
    • 38049187707 scopus 로고    scopus 로고
    • Reprogramming of human somatic cells to pluripotency with defined factors
    • Park I-H, Zhao R., West J. A., et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature: 2008; 451 7175 141 146
    • (2008) Nature , vol.451 , Issue.7175 , pp. 141-146
    • Park, I.-H.1    Zhao, R.2    West, J.A.3
  • 18
    • 79952900560 scopus 로고    scopus 로고
    • Turning straw into gold: Directing cell fate for regenerative medicine
    • Cohen D. E., Melton D. Turning straw into gold: directing cell fate for regenerative medicine. Nat Rev Genet: 2011; 12 4 243 252
    • (2011) Nat Rev Genet , vol.12 , Issue.4 , pp. 243-252
    • Cohen, D.E.1    Melton, D.2
  • 19
    • 57849128497 scopus 로고    scopus 로고
    • Nuclear reprogramming in cells
    • Gurdon J. B., Melton D. A. Nuclear reprogramming in cells. Science: 2008; 322 5909 1811 1815
    • (2008) Science , vol.322 , Issue.5909 , pp. 1811-1815
    • Gurdon, J.B.1    Melton, D.A.2
  • 21
    • 0035967892 scopus 로고    scopus 로고
    • The evolving concept of a stem cell: Entity or function?
    • DOI 10.1016/S0092-8674(01)00409-3
    • Blau H. M., Brazelton T. R., Weimann J. M. The evolving concept of a stem cell: entity or function? Cell: 2001; 105 7 829 841 (Pubitemid 32635085)
    • (2001) Cell , vol.105 , Issue.7 , pp. 829-841
    • Blau, H.M.1    Brazelton, T.R.2    Weimann, J.M.3
  • 22
    • 70450224866 scopus 로고    scopus 로고
    • Induced pluripotent stem cells and reprogramming: Seeing the science through the hype
    • Izpisúa Belmonte J. C., Ellis J., Hochedlinger K., Yamanaka S. Induced pluripotent stem cells and reprogramming: seeing the science through the hype. Nat Rev Genet: 2009; 10 12 878 883
    • (2009) Nat Rev Genet , vol.10 , Issue.12 , pp. 878-883
    • Izpisúa Belmonte, J.C.1    Ellis, J.2    Hochedlinger, K.3    Yamanaka, S.4
  • 23
    • 84856007232 scopus 로고    scopus 로고
    • The promise of induced pluripotent stem cells in research and therapy
    • Robinton D. A., Daley G. Q. The promise of induced pluripotent stem cells in research and therapy. Nature: 2012; 481 7381 295 305
    • (2012) Nature , vol.481 , Issue.7381 , pp. 295-305
    • Robinton, D.A.1    Daley, G.Q.2
  • 24
    • 77958569435 scopus 로고    scopus 로고
    • Induced pluripotency: History, mechanisms, and applications
    • Stadtfeld M., Hochedlinger K. Induced pluripotency: history, mechanisms, and applications. Genes Dev: 2010; 24 20 2239 2263
    • (2010) Genes Dev , vol.24 , Issue.20 , pp. 2239-2263
    • Stadtfeld, M.1    Hochedlinger, K.2
  • 25
    • 56549127713 scopus 로고    scopus 로고
    • Guidelines and techniques for the generation of induced pluripotent stem cells
    • Maherali N., Hochedlinger K. Guidelines and techniques for the generation of induced pluripotent stem cells. Cell Stem Cell: 2008; 3 6 595 605
    • (2008) Cell Stem Cell , vol.3 , Issue.6 , pp. 595-605
    • Maherali, N.1    Hochedlinger, K.2
  • 26
    • 50549089957 scopus 로고    scopus 로고
    • Disease-specific induced pluripotent stem cells
    • Park I-H, Arora N., Huo H., et al. Disease-specific induced pluripotent stem cells. Cell: 2008; 134 5 877 886
    • (2008) Cell , vol.134 , Issue.5 , pp. 877-886
    • Park, I.-H.1    Arora, N.2    Huo, H.3
  • 27
    • 70349437501 scopus 로고    scopus 로고
    • Generation of pluripotent stem cells from patients with type 1 diabetes
    • Maehr R., Chen S., Snitow M., et al. Generation of pluripotent stem cells from patients with type 1 diabetes. Proc Natl Acad Sci U S A: 2009; 106 37 15768 15773
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.37 , pp. 15768-15773
    • Maehr, R.1    Chen, S.2    Snitow, M.3
  • 28
    • 84865341342 scopus 로고    scopus 로고
    • Generation of disease-specific induced pluripotent stem cells from patients with different karyotypes of Down syndrome
    • Mou X., Wu Y., Cao H., et al. Generation of disease-specific induced pluripotent stem cells from patients with different karyotypes of Down syndrome. Stem Cell Res Ther: 2012; 3 2 14
    • (2012) Stem Cell Res Ther , vol.3 , Issue.2 , pp. 14
    • Mou, X.1    Wu, Y.2    Cao, H.3
  • 29
    • 84860510280 scopus 로고    scopus 로고
    • Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease
    • Sánchez-Danés A., Richaud-Patin Y., Carballo-Carbajal I., et al. Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease. EMBO Molecular Medicine: 2012; 4 1 16
    • (2012) EMBO Molecular Medicine , vol.4 , pp. 1-16
    • Sánchez-Danés, A.1    Richaud-Patin, Y.2    Carballo-Carbajal, I.3
  • 30
    • 84857125662 scopus 로고    scopus 로고
    • Modeling hepatitis C virus infection using human induced pluripotent stem cells
    • Schwartz R. E., Trehan K., Andrus L., et al. Modeling hepatitis C virus infection using human induced pluripotent stem cells. Proc Natl Acad Sci U S A: 2012; 109 7 2544 2548
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.7 , pp. 2544-2548
    • Schwartz, R.E.1    Trehan, K.2    Andrus, L.3
  • 31
    • 80054987997 scopus 로고    scopus 로고
    • Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells
    • Yusa K., Rashid S. T., Strick-Marchand H., et al. Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells. Nature: 2011; 478 7369 391 394
    • (2011) Nature , vol.478 , Issue.7369 , pp. 391-394
    • Yusa, K.1    Rashid, S.T.2    Strick-Marchand, H.3
  • 32
    • 49349116007 scopus 로고    scopus 로고
    • Liver disease in alpha 1-antitrypsin deficiency: A review
    • quiz 2142
    • Fairbanks K. D., Tavill A. S. Liver disease in alpha 1-antitrypsin deficiency: a review. Am J Gastroenterol: 2008; 103 8 2136 2141, quiz 2142
    • (2008) Am J Gastroenterol , vol.103 , Issue.8 , pp. 2136-2141
    • Fairbanks, K.D.1    Tavill, A.S.2
  • 33
    • 46149105683 scopus 로고    scopus 로고
    • Hereditary alpha-1-antitrypsin deficiency and its clinical consequences
    • Fregonese L., Stolk J. Hereditary alpha-1-antitrypsin deficiency and its clinical consequences. Orphanet J Rare Dis: 2008; 3 16
    • (2008) Orphanet J Rare Dis , vol.3 , pp. 16
    • Fregonese, L.1    Stolk, J.2
  • 34
    • 34248642305 scopus 로고    scopus 로고
    • Molecular pathogenesis of alpha-1-antitrypsin deficiency-associated liver disease: A meeting review
    • DOI 10.1002/hep.21628
    • Perlmutter D. H., Brodsky J. L., Balistreri W. F., Trapnell B. C. Molecular pathogenesis of alpha-1-antitrypsin deficiency-associated liver disease: a meeting review. Hepatology: 2007; 45 5 1313 1323 (Pubitemid 46775796)
    • (2007) Hepatology , vol.45 , Issue.5 , pp. 1313-1323
    • Perlmutter, D.H.1    Brodsky, J.L.2    Balistreri, W.F.3    Trapnell, B.C.4
  • 35
    • 80055028415 scopus 로고    scopus 로고
    • Induced pluripotent stem cells from hair follicles as a cellular model for neurodevelopmental disorders
    • Petit I., Kesner N. S., Karry R., et al. Induced pluripotent stem cells from hair follicles as a cellular model for neurodevelopmental disorders. Stem Cell Res (Amst): 2012; 8 1 134 140
    • (2012) Stem Cell Res (Amst) , vol.8 , Issue.1 , pp. 134-140
    • Petit, I.1    Kesner, N.S.2    Karry, R.3
  • 36
    • 77950623520 scopus 로고    scopus 로고
    • IPS cells reprogrammed from human mesenchymal-like stem/progenitor cells of dental tissue origin
    • Yan X., Qin H., Qu C., Tuan R. S., Shi S., Huang G. T. iPS cells reprogrammed from human mesenchymal-like stem/progenitor cells of dental tissue origin. Stem Cells Dev: 2010; 19 4 469 480
    • (2010) Stem Cells Dev , vol.19 , Issue.4 , pp. 469-480
    • Yan, X.1    Qin, H.2    Qu, C.3    Tuan, R.S.4    Shi, S.5    Huang, G.T.6
  • 37
    • 77955449906 scopus 로고    scopus 로고
    • Epigenetic memory in induced pluripotent stem cells
    • Kim K., Doi A., Wen B., et al. Epigenetic memory in induced pluripotent stem cells. Nature: 2010; 467 7313 285 290
    • (2010) Nature , vol.467 , Issue.7313 , pp. 285-290
    • Kim, K.1    Doi, A.2    Wen, B.3
  • 38
    • 79957998057 scopus 로고    scopus 로고
    • DNA methylation dynamics in human induced pluripotent stem cells over time
    • Nishino K., Toyoda M., Yamazaki-Inoue M., et al. DNA methylation dynamics in human induced pluripotent stem cells over time. PLoS Genet: 2011; 7 5 e1002085
    • (2011) PLoS Genet , vol.7 , Issue.5
    • Nishino, K.1    Toyoda, M.2    Yamazaki-Inoue, M.3
  • 39
    • 70450285340 scopus 로고    scopus 로고
    • Technical challenges in using human induced pluripotent stem cells to model disease
    • Saha K., Jaenisch R. Technical challenges in using human induced pluripotent stem cells to model disease. Cell Stem Cell: 2009; 5 6 584 595
    • (2009) Cell Stem Cell , vol.5 , Issue.6 , pp. 584-595
    • Saha, K.1    Jaenisch, R.2
  • 40
    • 64749111225 scopus 로고    scopus 로고
    • Virus-free induction of pluripotency and subsequent excision of reprogramming factors
    • Kaji K., Norrby K., Paca A., Mileikovsky M., Mohseni P., Woltjen K. Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature: 2009; 458 7239 771 775
    • (2009) Nature , vol.458 , Issue.7239 , pp. 771-775
    • Kaji, K.1    Norrby, K.2    Paca, A.3    Mileikovsky, M.4    Mohseni, P.5    Woltjen, K.6
  • 41
    • 72849137462 scopus 로고    scopus 로고
    • Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells
    • Zhou W., Freed C. R. Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells. Stem Cells: 2009; 27 11 2667 2674
    • (2009) Stem Cells , vol.27 , Issue.11 , pp. 2667-2674
    • Zhou, W.1    Freed, C.R.2
  • 42
    • 84863229606 scopus 로고    scopus 로고
    • Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by nonintegrating plasmid expression
    • NISC Comparative Sequencing Program
    • Cheng L., Hansen N. F., Zhao L., et al. NISC Comparative Sequencing Program Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by nonintegrating plasmid expression. Cell Stem Cell: 2012; 10 3 337 344
    • (2012) Cell Stem Cell , vol.10 , Issue.3 , pp. 337-344
    • Cheng, L.1    Hansen, N.F.2    Zhao, L.3
  • 43
    • 64749083939 scopus 로고    scopus 로고
    • PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
    • Woltjen K., Michael I. P., Mohseni P., et al. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature: 2009; 458 7239 766 770
    • (2009) Nature , vol.458 , Issue.7239 , pp. 766-770
    • Woltjen, K.1    Michael, I.P.2    Mohseni, P.3
  • 44
    • 79551665440 scopus 로고    scopus 로고
    • A functionally characterized test set of human induced pluripotent stem cells
    • Boulting G. L., Kiskinis E., Croft G. F., et al. A functionally characterized test set of human induced pluripotent stem cells. Nat Biotechnol: 2011; 29 3 279 286
    • (2011) Nat Biotechnol , vol.29 , Issue.3 , pp. 279-286
    • Boulting, G.L.1    Kiskinis, E.2    Croft, G.F.3
  • 45
    • 68249087053 scopus 로고    scopus 로고
    • Variation in the safety of induced pluripotent stem cell lines
    • Miura K., Okada Y., Aoi T., et al. Variation in the safety of induced pluripotent stem cell lines. Nat Biotechnol: 2009; 27 8 743 745
    • (2009) Nat Biotechnol , vol.27 , Issue.8 , pp. 743-745
    • Miura, K.1    Okada, Y.2    Aoi, T.3
  • 47
    • 79960836456 scopus 로고    scopus 로고
    • Genetic engineering of human pluripotent cells using TALE nuclease
    • Hockemeyer D., Wang H., Kiani S., et al. Genetic engineering of human pluripotent cells using TALE nuclease. Nat Biotechnol: 2011; 29 8 731 734
    • (2011) Nat Biotechnol , vol.29 , Issue.8 , pp. 731-734
    • Hockemeyer, D.1    Wang, H.2    Kiani, S.3
  • 48
    • 0025333289 scopus 로고
    • Evolution of the P450 gene superfamily: Animal-plant 'warfare', molecular drive and human genetic differences in drug oxidation
    • Gonzalez F. J., Nebert D. W. Evolution of the P450 gene superfamily: animal-plant 'warfare', molecular drive and human genetic differences in drug oxidation. Trends Genet: 1990; 6 6 182 186
    • (1990) Trends Genet , vol.6 , Issue.6 , pp. 182-186
    • Gonzalez, F.J.1    Nebert, D.W.2
  • 49
    • 0028818229 scopus 로고
    • Species similarities and differences in pharmacokinetics
    • Lin J. H. Species similarities and differences in pharmacokinetics. Drug Metab Dispos: 1995; 23 10 1008 1021
    • (1995) Drug Metab Dispos , vol.23 , Issue.10 , pp. 1008-1021
    • Lin, J.H.1
  • 50
    • 19444376971 scopus 로고    scopus 로고
    • Drug metabolism and variability among patients in drug response
    • Wilkinson G. R. Drug metabolism and variability among patients in drug response. N Engl J Med: 2005; 352 21 2211 2221
    • (2005) N Engl J Med , vol.352 , Issue.21 , pp. 2211-2221
    • Wilkinson, G.R.1
  • 51
    • 0035907098 scopus 로고    scopus 로고
    • Hepatic maturation in differentiating embryonic stem cells in vitro
    • DOI 10.1016/S0014-5793(01)02423-1, PII S0014579301024231
    • Hamazaki T., Iiboshi Y., Oka M., et al. Hepatic maturation in differentiating embryonic stem cells in vitro. FEBS Lett: 2001; 497 1 15 19 (Pubitemid 32480173)
    • (2001) FEBS Letters , vol.497 , Issue.1 , pp. 15-19
    • Hamazaki, T.1    Iiboshi, Y.2    Oka, M.3    Papst, P.J.4    Meacham, A.M.5    Zon, L.I.6    Terada, N.7
  • 53
    • 77951480489 scopus 로고    scopus 로고
    • Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development
    • Touboul T., Hannan N. RF, Corbineau S., et al. Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development. Hepatology: 2010; 51 5 1754 1765
    • (2010) Hepatology , vol.51 , Issue.5 , pp. 1754-1765
    • Touboul, T.1    Hannan, N.R.2    Corbineau, S.3
  • 55
    • 39349106325 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cells to clinically relevant populations: Lessons from embryonic development
    • DOI 10.1016/j.cell.2008.02.008, PII S009286740800216X
    • Murry C. E., Keller G. Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell: 2008; 132 4 661 680 (Pubitemid 351260059)
    • (2008) Cell , vol.132 , Issue.4 , pp. 661-680
    • Murry, C.E.1    Keller, G.2
  • 56
    • 68549128962 scopus 로고    scopus 로고
    • Directed differentiation of pluripotent stem cells: From developmental biology to therapeutic applications
    • Irion S., Nostro M. C., Kattman S. J., Keller G. M. Directed differentiation of pluripotent stem cells: from developmental biology to therapeutic applications. Cold Spring Harb Symp Quant Biol: 2008; 73 101 110
    • (2008) Cold Spring Harb Symp Quant Biol , vol.73 , pp. 101-110
    • Irion, S.1    Nostro, M.C.2    Kattman, S.J.3    Keller, G.M.4
  • 57
    • 79960311063 scopus 로고    scopus 로고
    • New approaches in the differentiation of human embryonic stem cells and induced pluripotent stem cells toward hepatocytes
    • Behbahan I. S., Duan Y., Lam A., et al. New approaches in the differentiation of human embryonic stem cells and induced pluripotent stem cells toward hepatocytes. Stem Cell Rev: 2011; 7 3 748 759
    • (2011) Stem Cell Rev , vol.7 , Issue.3 , pp. 748-759
    • Behbahan, I.S.1    Duan, Y.2    Lam, A.3
  • 58
    • 77649340118 scopus 로고    scopus 로고
    • Generation of murine hepatic lineage cells from induced pluripotent stem cells
    • Gai H., Nguyen D. M., Moon Y. J., et al. Generation of murine hepatic lineage cells from induced pluripotent stem cells. Differentiation: 2010; 79 3 171 181
    • (2010) Differentiation , vol.79 , Issue.3 , pp. 171-181
    • Gai, H.1    Nguyen, D.M.2    Moon, Y.J.3
  • 59
    • 77950994754 scopus 로고    scopus 로고
    • Differentiation and characterization of metabolically functioning hepatocytes from human embryonic stem cells
    • Duan Y., Ma X., Zou W., et al. Differentiation and characterization of metabolically functioning hepatocytes from human embryonic stem cells. Stem Cells: 2010; 28 4 674 686
    • (2010) Stem Cells , vol.28 , Issue.4 , pp. 674-686
    • Duan, Y.1    Ma, X.2    Zou, W.3
  • 60
    • 84871391390 scopus 로고    scopus 로고
    • Differentiation and transplantation of human induced pluripotent stem cell-derived hepatocyte-like cells
    • Nov 11. [Epub ahead of print]
    • Asgari S., Moslem M., Bagheri-Lankarani K., et al. Differentiation and transplantation of human induced pluripotent stem cell-derived hepatocyte-like cells. Stem Cell Rev: 2011; Nov 11. [Epub ahead of print]
    • (2011) Stem Cell Rev
    • Asgari, S.1    Moslem, M.2    Bagheri-Lankarani, K.3
  • 61
    • 28644448149 scopus 로고    scopus 로고
    • Efficient differentiation of human embryonic stem cells to definitive endoderm
    • DOI 10.1038/nbt1163
    • D'Amour K. A., Agulnick A. D., Eliazer S., Kelly O. G., Kroon E., Baetge E. E. Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat Biotechnol: 2005; 23 12 1534 1541 (Pubitemid 41752931)
    • (2005) Nature Biotechnology , vol.23 , Issue.12 , pp. 1534-1541
    • D'Amour, K.A.1    Agulnick, A.D.2    Eliazer, S.3    Kelly, O.G.4    Kroon, E.5    Baetge, E.E.6
  • 62
    • 77957359924 scopus 로고    scopus 로고
    • Enhanced functions of human embryonic stem cell-derived hepatocyte-like cells on three-dimensional nanofibrillar surfaces
    • Farzaneh Z., Pournasr B., Ebrahimi M., Aghdami N., Baharvand H. Enhanced functions of human embryonic stem cell-derived hepatocyte-like cells on three-dimensional nanofibrillar surfaces. Stem Cell Rev: 2010; 6 4 601 610
    • (2010) Stem Cell Rev , vol.6 , Issue.4 , pp. 601-610
    • Farzaneh, Z.1    Pournasr, B.2    Ebrahimi, M.3    Aghdami, N.4    Baharvand, H.5
  • 64
    • 47949092668 scopus 로고    scopus 로고
    • Efficient differentiation of functional hepatocytes from human embryonic stem cells
    • Agarwal S., Holton K. L., Lanza R. Efficient differentiation of functional hepatocytes from human embryonic stem cells. Stem Cells: 2008; 26 5 1117 1127
    • (2008) Stem Cells , vol.26 , Issue.5 , pp. 1117-1127
    • Agarwal, S.1    Holton, K.L.2    Lanza, R.3
  • 65
    • 0036217604 scopus 로고    scopus 로고
    • In vitro differentiation of embryonic stem cells into hepatocyte-like cells identified by cellular uptake of indocyanine green
    • Yamada T., Yoshikawa M., Kanda S., et al. In vitro differentiation of embryonic stem cells into hepatocyte-like cells identified by cellular uptake of indocyanine green. Stem Cells: 2002; 20 2 146 154 (Pubitemid 34297262)
    • (2002) Stem Cells , vol.20 , Issue.2 , pp. 146-154
    • Yamada, T.1    Yoshikawa, M.2    Kanda, S.3    Kato, Y.4    Nakajima, Y.5    Ishizaka, S.6    Tsunoda, Y.7
  • 66
    • 60449098836 scopus 로고    scopus 로고
    • Differentiation and transplantation of human embryonic stem cell-derived hepatocytes
    • Basma H., Soto-Gutiérrez A., Yannam G. R., et al. Differentiation and transplantation of human embryonic stem cell-derived hepatocytes. Gastroenterology: 2009; 136 3 990 999
    • (2009) Gastroenterology , vol.136 , Issue.3 , pp. 990-999
    • Basma, H.1    Soto-Gutiérrez, A.2    Yannam, G.R.3
  • 67
    • 70449534874 scopus 로고    scopus 로고
    • Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells
    • Song Z., Cai J., Liu Y., et al. Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells. Cell Res: 2009; 19 11 1233 1242
    • (2009) Cell Res , vol.19 , Issue.11 , pp. 1233-1242
    • Song, Z.1    Cai, J.2    Liu, Y.3
  • 68
    • 73449100456 scopus 로고    scopus 로고
    • Generation of functional human hepatic endoderm from human induced pluripotent stem cells
    • Sullivan G. J., Hay D. C., Park I-H., et al. Generation of functional human hepatic endoderm from human induced pluripotent stem cells. Hepatology: 2010; 51 1 329 335
    • (2010) Hepatology , vol.51 , Issue.1 , pp. 329-335
    • Sullivan, G.J.1    Hay, D.C.2    Park, I.-H.3
  • 69
    • 73449100783 scopus 로고    scopus 로고
    • Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells
    • Si-Tayeb K., Noto F. K., Nagaoka M., et al. Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells. Hepatology: 2010; 51 1 297 305
    • (2010) Hepatology , vol.51 , Issue.1 , pp. 297-305
    • Si-Tayeb, K.1    Noto, F.K.2    Nagaoka, M.3
  • 70
    • 79960649307 scopus 로고    scopus 로고
    • Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors
    • Sekiya S., Suzuki A. Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors. Nature: 2011; 475 7356 390 393
    • (2011) Nature , vol.475 , Issue.7356 , pp. 390-393
    • Sekiya, S.1    Suzuki, A.2
  • 71
    • 79960637387 scopus 로고    scopus 로고
    • Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors
    • Huang P., He Z., Ji S., et al. Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors. Nature: 2011; 475 7356 386 389
    • (2011) Nature , vol.475 , Issue.7356 , pp. 386-389
    • Huang, P.1    He, Z.2    Ji, S.3
  • 72
    • 79961130581 scopus 로고    scopus 로고
    • A simple code for installing hepatocyte function
    • Willenbring H. A simple code for installing hepatocyte function. Cell Stem Cell: 2011; 9 2 89 91
    • (2011) Cell Stem Cell , vol.9 , Issue.2 , pp. 89-91
    • Willenbring, H.1
  • 73
    • 81555195723 scopus 로고    scopus 로고
    • Hepatic differentiation of murine disease-specific induced pluripotent stem cells allows disease modelling in vitro
    • Eggenschwiler R., Loya K., Sgodda M., André F., Cantz T. Hepatic differentiation of murine disease-specific induced pluripotent stem cells allows disease modelling in vitro. Stem Cells Int: 2011; 2011 924782 1 11
    • (2011) Stem Cells Int , vol.2011 , pp. 1-11
    • Eggenschwiler, R.1    Loya, K.2    Sgodda, M.3    André, F.4    Cantz, T.5
  • 74
    • 0035017233 scopus 로고    scopus 로고
    • Liver repopulation for the treatment of metabolic diseases
    • DOI 10.1023/A:1010375203539
    • Grompe M. Liver repopulation for the treatment of metabolic diseases. J Inherit Metab Dis: 2001; 24 2 231 244 (Pubitemid 32479417)
    • (2001) Journal of Inherited Metabolic Disease , vol.24 , Issue.2 , pp. 231-244
    • Grompe, M.1
  • 75
    • 57649181445 scopus 로고    scopus 로고
    • Autophagic disposal of the aggregation-prone protein that causes liver inflammation and carcinogenesis in α-1-antitrypsin deficiency
    • Perlmutter D. H. Autophagic disposal of the aggregation-prone protein that causes liver inflammation and carcinogenesis in α-1-antitrypsin deficiency. Cell Death Differ: 2009; 16 1 39 45
    • (2009) Cell Death Differ , vol.16 , Issue.1 , pp. 39-45
    • Perlmutter, D.H.1
  • 77
    • 33748419472 scopus 로고    scopus 로고
    • The role of autophagy in α-1-antitrypsin deficiency: A specific cellular response in genetic diseases associated with aggregation-prone proteins
    • Perlmutter D. H. The role of autophagy in alpha-1-antitrypsin deficiency: a specific cellular response in genetic diseases associated with aggregation-prone proteins. Autophagy: 2006; 2 4 258 263 (Pubitemid 44342367)
    • (2006) Autophagy , vol.2 , Issue.4 , pp. 258-263
    • Perlmutter, D.H.1
  • 78
    • 77956354416 scopus 로고    scopus 로고
    • Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells
    • Rashid S. T., Corbineau S., Hannan N., et al. Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. J Clin Invest: 2010; 120 9 3127 3136
    • (2010) J Clin Invest , vol.120 , Issue.9 , pp. 3127-3136
    • Rashid, S.T.1    Corbineau, S.2    Hannan, N.3
  • 79
    • 33845981514 scopus 로고    scopus 로고
    • PiggyBac transposon-mediated gene transfer in human cells
    • DOI 10.1038/sj.mt.6300028, PII 6300028
    • Wilson M. H., Coates C. J., George A. L. Jr. PiggyBac transposon-mediated gene transfer in human cells. Mol Ther: 2007; 15 1 139 145 (Pubitemid 46043659)
    • (2007) Molecular Therapy , vol.15 , Issue.1 , pp. 139-145
    • Wilson, M.H.1    Coates, C.J.2    George Jr., A.L.3
  • 80
    • 79959772184 scopus 로고    scopus 로고
    • Size matters: Versatile use of PiggyBac transposons as a genetic manipulation tool
    • Kim A., Pyykko I. Size matters: versatile use of PiggyBac transposons as a genetic manipulation tool. Mol Cell Biochem: 2011; 354 1-2 301 309
    • (2011) Mol Cell Biochem , vol.354 , Issue.12 , pp. 301-309
    • Kim, A.1    Pyykko, I.2
  • 81
    • 4143091598 scopus 로고    scopus 로고
    • The glycogen storage diseases
    • DOI 10.1016/j.cupe.2004.05.004, PII S0957583904000636
    • Mundy H., Lee P. J. The glycogen storage diseases. Curr Paediatr: 2004; 14 407 413 (Pubitemid 39094459)
    • (2004) Current Paediatrics , vol.14 , Issue.5 , pp. 407-413
    • Mundy, H.1    Lee, P.J.2
  • 82
    • 34250661859 scopus 로고    scopus 로고
    • Glycogen storage diseases: New perspectives
    • Ozen H. Glycogen storage diseases: new perspectives. World J Gastroenterol: 2007; 13 18 2541 2553 (Pubitemid 46938823)
    • (2007) World Journal of Gastroenterology , vol.13 , Issue.18 , pp. 2541-2553
    • Ozen, H.1
  • 83
    • 78649449365 scopus 로고    scopus 로고
    • Glycogen storage disease type i and G6Pase-β deficiency: Etiology and therapy
    • Chou J. Y., Jun H. S., Mansfield B. C. Glycogen storage disease type I and G6Pase-β deficiency: etiology and therapy. Nat Rev Endocrinol: 2010; 6 12 676 688
    • (2010) Nat Rev Endocrinol , vol.6 , Issue.12 , pp. 676-688
    • Chou, J.Y.1    Jun, H.S.2    Mansfield, B.C.3
  • 84
    • 40149095619 scopus 로고    scopus 로고
    • Liver transplantation in children with glycogen storage disease: Controversies and evaluation of the risk/benefit of this procedure
    • DOI 10.1111/j.1399-3046.2007.00803.x
    • Davis M. K., Weinstein D. A. Liver transplantation in children with glycogen storage disease: controversies and evaluation of the risk/benefit of this procedure. Pediatr Transplant: 2008; 12 2 137 145 (Pubitemid 351326916)
    • (2008) Pediatric Transplantation , vol.12 , Issue.2 , pp. 137-145
    • Davis, M.K.1    Weinstein, D.A.2
  • 85
    • 80051801810 scopus 로고    scopus 로고
    • Natural history of hepatocellular adenoma formation in glycogen storage disease type i
    • Wang D. Q., Fiske L. M., Carreras C. T., Weinstein D. A. Natural history of hepatocellular adenoma formation in glycogen storage disease type I. J Pediatr: 2011; 159 3 442 446
    • (2011) J Pediatr , vol.159 , Issue.3 , pp. 442-446
    • Wang, D.Q.1    Fiske, L.M.2    Carreras, C.T.3    Weinstein, D.A.4
  • 86
    • 40849134097 scopus 로고    scopus 로고
    • Hepatocellular adenoma and metabolic balance in patients with type Ia glycogen storage disease
    • Di Rocco M., Calevo M. G., Taro' M., Melis D., Allegri A. E., Parenti G. Hepatocellular adenoma and metabolic balance in patients with type Ia glycogen storage disease. Mol Genet Metab: 2008; 93 4 398 402
    • (2008) Mol Genet Metab , vol.93 , Issue.4 , pp. 398-402
    • Di Rocco, M.1    Calevo, M.G.2    Taro, M.3    Melis, D.4    Allegri, A.E.5    Parenti, G.6
  • 88
    • 0033508544 scopus 로고    scopus 로고
    • Effect of continuous glucose therapy begun in infancy on the long-term clinical course of patients with type I glycogen storage disease
    • DOI 10.1097/00005176-199908000-00008
    • Wolfsdorf J. I., Crigler J. F. Jr. Effect of continuous glucose therapy begun in infancy on the long-term clinical course of patients with type I glycogen storage disease. J Pediatr Gastroenterol Nutr: 1999; 29 2 136 143 (Pubitemid 30366162)
    • (1999) Journal of Pediatric Gastroenterology and Nutrition , vol.29 , Issue.2 , pp. 136-143
    • Wolfsdorf, J.I.1    Crigler Jr., J.F.2
  • 89
    • 32444436226 scopus 로고    scopus 로고
    • Long-term correction of murine glycogen storage disease type la by recombinant adeno-associated virus-1-mediated gene transfer
    • DOI 10.1038/sj.gt.3302650, PII 3302650
    • Ghosh A., Allamarvdasht M., Pan C-J., et al. Long-term correction of murine glycogen storage disease type Ia by recombinant adeno-associated virus-1-mediated gene transfer. Gene Ther: 2006; 13 4 321 329 (Pubitemid 43223101)
    • (2006) Gene Therapy , vol.13 , Issue.4 , pp. 321-329
    • Ghosh, A.1    Allamarvdasht, M.2    Pan, C.-J.3    Sun, M.-S.4    Mansfield, B.C.5    Byrne, B.J.6    Chou, J.Y.7
  • 90
    • 34247558169 scopus 로고    scopus 로고
    • Gene therapy for type I glycogen storage diseases
    • DOI 10.2174/156652307780363152
    • Chou J. Y., Mansfield B. C. Gene therapy for type I glycogen storage diseases. Curr Gene Ther: 2007; 7 2 79 88 (Pubitemid 46681766)
    • (2007) Current Gene Therapy , vol.7 , Issue.2 , pp. 79-88
    • Chou, J.Y.1    Mansfield, B.C.2
  • 91
    • 26244451432 scopus 로고    scopus 로고
    • Gene therapy for inborn errors of liver metabolism
    • DOI 10.1016/j.ymgme.2005.07.015, PII S1096719205002283, ASHG 2005 Meeting Salt Lake City
    • Brunetti-Pierri N., Lee B. Gene therapy for inborn errors of liver metabolism. Mol Genet Metab: 2005; 86 1-2 13 24 (Pubitemid 41412158)
    • (2005) Molecular Genetics and Metabolism , vol.86 , Issue.1-2 , pp. 13-24
    • Brunetti-Pierri, N.1    Lee, B.2
  • 92
    • 33745084945 scopus 로고    scopus 로고
    • Hepatocyte transplantation for liver-based metabolic disorders
    • DOI 10.1007/s10545-006-0245-8
    • Dhawan A., Mitry R. R., Hughes R. D. Hepatocyte transplantation for liver-based metabolic disorders. J Inherit Metab Dis: 2006; 29 2-3 431 435 (Pubitemid 43880647)
    • (2006) Journal of Inherited Metabolic Disease , vol.29 , Issue.2-3 , pp. 431-435
    • Dhawan, A.1    Mitry, R.R.2    Hughes, R.D.3
  • 93
    • 81255188000 scopus 로고    scopus 로고
    • Familial hypercholesterolemia: Present and future management
    • Sjouke B., Kusters D. M., Kastelein J. JP, Hovingh G. K. Familial hypercholesterolemia: present and future management. Curr Cardiol Rep: 2011; 13 6 527 536
    • (2011) Curr Cardiol Rep , vol.13 , Issue.6 , pp. 527-536
    • Sjouke, B.1    Kusters, D.M.2    Kastelein, J.J.3    Hovingh, G.K.4
  • 94
    • 79955017150 scopus 로고    scopus 로고
    • Familial hypercholesterolemia: The lipids or the genes
    • Fahed A. C., Nemer G. M. Familial hypercholesterolemia: the lipids or the genes? Nutr Metab (Lond): 2011; 8 1 23
    • (2011) Nutr Metab (Lond) , vol.8 , Issue.1 , pp. 23
    • Fahed, A.C.1    Nemer, G.M.2
  • 95
    • 33947679772 scopus 로고    scopus 로고
    • Mechanisms of disease: Genetic causes of familial hypercholesterolemia
    • DOI 10.1038/ncpcardio0836, PII NCPCARDIO0836
    • Soutar A. K., Naoumova R. P. Mechanisms of disease: genetic causes of familial hypercholesterolemia. Nat Clin Pract Cardiovasc Med: 2007; 4 4 214 225 (Pubitemid 46502094)
    • (2007) Nature Clinical Practice Cardiovascular Medicine , vol.4 , Issue.4 , pp. 214-225
    • Soutar, A.K.1    Naoumova, R.P.2
  • 97
    • 16344364326 scopus 로고    scopus 로고
    • Expression genomics and drug development: Towards predictive pharmacology
    • DOI 10.1093/bfgp/3.4.303
    • Liu E. T. Expression genomics and drug development: towards predictive pharmacology. Brief Funct Genomics Proteomics: 2005; 3 4 303 321 (Pubitemid 40468215)
    • (2005) Briefings in Functional Genomics and Proteomics , vol.3 , Issue.4 , pp. 303-321
    • Liu, E.T.1
  • 98
    • 77957347780 scopus 로고    scopus 로고
    • Generation of liver disease-specific induced pluripotent stem cells along with efficient differentiation to functional hepatocyte-like cells
    • Ghodsizadeh A., Taei A., Totonchi M., et al. Generation of liver disease-specific induced pluripotent stem cells along with efficient differentiation to functional hepatocyte-like cells. Stem Cell Rev: 2010; 6 4 622 632
    • (2010) Stem Cell Rev , vol.6 , Issue.4 , pp. 622-632
    • Ghodsizadeh, A.1    Taei, A.2    Totonchi, M.3
  • 99
    • 56049117209 scopus 로고    scopus 로고
    • End-stage liver disease and liver transplant: Current situation and key issues
    • End-Stage Liver Disease Working Group
    • Sokal E. M., Goldstein D., Ciocca M., et al. End-Stage Liver Disease Working Group End-stage liver disease and liver transplant: current situation and key issues. J Pediatr Gastroenterol Nutr: 2008; 47 2 239 246
    • (2008) J Pediatr Gastroenterol Nutr , vol.47 , Issue.2 , pp. 239-246
    • Sokal, E.M.1    Goldstein, D.2    Ciocca, M.3
  • 100
    • 84873702623 scopus 로고    scopus 로고
    • Liver transplantation in acute alcoholic hepatitis: Current status and future development
    • Singal A. K., Duchini A. Liver transplantation in acute alcoholic hepatitis: Current status and future development. World J Hepatol: 2011; 3 8 215 218
    • (2011) World J Hepatol , vol.3 , Issue.8 , pp. 215-218
    • Singal, A.K.1    Duchini, A.2
  • 101
    • 33645541715 scopus 로고    scopus 로고
    • Trends over a decade of pediatric liver transplantation in the United States
    • Feng S., Si M., Taranto S. E., et al. Trends over a decade of pediatric liver transplantation in the United States. Liver Transpl: 2006; 12 4 578 584
    • (2006) Liver Transpl , vol.12 , Issue.4 , pp. 578-584
    • Feng, S.1    Si, M.2    Taranto, S.E.3
  • 102
    • 34249090194 scopus 로고    scopus 로고
    • Liver transplantation for status 1: The consequences of good intentions
    • DOI 10.1002/lt.21125
    • McDiarmid S. V., Goodrich N. P., Harper A. M., Merion R. M. Liver transplantation for status 1: the consequences of good intentions. Liver Transpl: 2007; 13 5 699 707 (Pubitemid 46796542)
    • (2007) Liver Transplantation , vol.13 , Issue.5 , pp. 699-707
    • McDiarmid, S.V.1    Goodrich, N.P.2    Harper, A.M.3    Merion, R.M.4
  • 103
    • 79958812975 scopus 로고    scopus 로고
    • Stem cell-based therapies for liver diseases: State of the art and new perspectives
    • Piscaglia A. C., Campanale M., Gasbarrini A., Gasbarrini G. Stem cell-based therapies for liver diseases: state of the art and new perspectives. Stem Cells Int: 2010; 2010 259461 1 10
    • (2010) Stem Cells Int , vol.2010 , pp. 1-10
    • Piscaglia, A.C.1    Campanale, M.2    Gasbarrini, A.3    Gasbarrini, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.