ADAM15 deficiency attenuates pulmonary hyperpermeability and acute lung injury in lipopolysaccharide-treated mice

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 304, Issue 3, 2013, Pages

  Sun, Chongxiu ^b   Beard, Richard S ^a   Mclean, Danielle L ^a   Rigor, Robert R ^b   Konia, Thomas ^b   Wu, Mack H ^a,b   Yuan, Sarah Y ^a,b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Endothelial dysfunction; Inflammation; Metalloproteinase; Vascular permeability

Indexed keywords

ADAM PROTEIN; ADAM15 PROTEIN; ALBUMIN; BACTERIUM LIPOPOLYSACCHARIDE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; MYELOPEROXIDASE; UNCLASSIFIED DRUG;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DISEASE ASSOCIATION; DRY WEIGHT; ELECTRIC RESISTANCE; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVITY; GENE INACTIVATION; IMMUNOFLUORESCENCE TEST; LUNG EDEMA; LUNG ENDOTHELIUM; LUNG ENDOTHELIUM HYPERPERMEABILITY; LUNG LAVAGE; LUNG PARENCHYMA; LUNG WEIGHT; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL COUNT; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; PULMONARY MICROVASCULAR LEAKAGE; PULMONARY VASCULAR DISEASE; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; UPREGULATION; WESTERN BLOTTING;

ACUTE LUNG INJURY; ADAM PROTEINS; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; ELECTRIC IMPEDANCE; ENDOTHELIAL CELLS; LIPOPOLYSACCHARIDES; LUNG; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; NEUTROPHIL INFILTRATION; NEUTROPHILS; PERMEABILITY; PEROXIDASE; PRIMARY CELL CULTURE; PULMONARY EDEMA; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; UP-REGULATION;

EID: 84873333125     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00133.2012     Document Type: Article

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