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Volumn 24, Issue 3, 2013, Pages 385-397

Reduced TOR signaling sustains hyphal development in Candida albicans by lowering Hog1 basal activity

Author keywords

[No Author keywords available]

Indexed keywords

BRG1 PROTEIN; FUNGAL PROTEIN; GLYCEROL; HIGH OSMOLARITY GLYCEROL 1; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN PBS2; PROTEIN PTP2; PROTEIN PTP3; PROTEIN SSK2; TARGET OF RAPAMYCIN KINASE; UNCLASSIFIED DRUG;

EID: 84873328069     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E12-06-0477     Document Type: Article
Times cited : (73)

References (66)
  • 1
    • 0035012401 scopus 로고    scopus 로고
    • Stress-induced map kinase hog1 is part of transcription activation complexes
    • Alepuz PM, Jovanovic A, Reiser V, Ammerer G (2001). Stress-induced map kinase Hog1 is part of transcription activation complexes. Mol Cell 7, 767-777.
    • (2001) Mol Cell , vol.7 , pp. 767-777
    • Alepuz, P.M.1    Jovanovic, A.2    Reiser, V.3    Ammerer, G.4
  • 3
    • 77955698259 scopus 로고    scopus 로고
    • The sko1 protein represses the yeast-to-hypha transition and regulates the oxidative stress response in candida albicans
    • Alonso-Monge R, Roman E, Arana DM, Prieto D, Urrialde V, Nombela C, Pla J (2010). The Sko1 protein represses the yeast-to-hypha transition and regulates the oxidative stress response in Candida albicans. Fungal Genet Biol 47, 587-601.
    • (2010) Fungal Genet Biol , vol.47 , pp. 587-601
    • Alonso-Monge, R.1    Roman, E.2    Arana, D.M.3    Prieto, D.4    Urrialde, V.5    Nombela, C.6    Pla, J.7
  • 4
    • 17644384332 scopus 로고    scopus 로고
    • The pbs2 map kinase kinase is essential for the oxidative-stress response in the fungal pathogen candida albicans
    • Arana DM, Nombela C, Alonso-Monge R, Pla J (2005). The Pbs2 MAP kinase kinase is essential for the oxidative-stress response in the fungal pathogen Candida albicans. Microbiology 151, 1033-1049.
    • (2005) Microbiology , vol.151 , pp. 1033-1049
    • Arana, D.M.1    Nombela, C.2    Alonso-Monge, R.3    Pla, J.4
  • 5
    • 0036001334 scopus 로고    scopus 로고
    • Stt4 pi 4-kinase localizes to the plasma membrane and functions in the pkc1-mediated map kinase cascade
    • Audhya A, Emr SD (2002). Stt4 PI 4-kinase localizes to the plasma membrane and functions in the Pkc1-mediated MAP kinase cascade. Dev Cell 2, 593-605.
    • (2002) Dev Cell , vol.2 , pp. 593-605
    • Audhya, A.1    Emr, S.D.2
  • 6
    • 0035033538 scopus 로고    scopus 로고
    • Cap1, an adenylate cyclase-associated protein gene, regulates bud-hypha transitions, filamentous growth, and cyclic amp levels and is required for virulence of candida albicans
    • Bahn YS, Sundstrom P (2001). CAP1, an adenylate cyclase-associated protein gene, regulates bud-hypha transitions, filamentous growth, and cyclic AMP levels and is required for virulence of Candida albicans. J Bacteriol 183, 3211-3222.
    • (2001) J Bacteriol , vol.183 , pp. 3211-3222
    • Bahn, Y.S.1    Sundstrom, P.2
  • 7
    • 61449094788 scopus 로고    scopus 로고
    • The protein kinase tor1 regulates adhesin gene expression in candida albicans
    • Bastidas RJ, Heitman J, Cardenas ME (2009). The protein kinase Tor1 regulates adhesin gene expression in Candida albicans. PLoS Pathog 5, e1000294.
    • (2009) PLoS Pathog , vol.5
    • Bastidas, R.J.1    Heitman, J.2    Cardenas, M.E.3
  • 8
    • 9644262800 scopus 로고    scopus 로고
    • Transcriptional profiling in candida albicans reveals new adaptive responses to extracellular ph and functions for rim101p
    • Bensen ES, Martin SJ, Li M, Berman J, Davis DA (2004). Transcriptional profiling in Candida albicans reveals new adaptive responses to extracellular pH and functions for Rim101p. Mol Microbiol 54, 1335-1351.
    • (2004) Mol Microbiol , vol.54 , pp. 1335-1351
    • Bensen, E.S.1    Martin, S.J.2    Li, M.3    Berman, J.4    Davis, D.A.5
  • 10
    • 0035053398 scopus 로고    scopus 로고
    • A potential phosphorylation site for an a-type kinase in the efg1 regulator protein contributes to hyphal morphogenesis of candida albicans
    • Bockmuhl DP, Ernst JF (2001). A potential phosphorylation site for an A-type kinase in the Efg1 regulator protein contributes to hyphal morphogenesis of Candida albicans. Genetics 157, 1523-1530.
    • (2001) Genetics , vol.157 , pp. 1523-1530
    • Bockmuhl, D.P.1    Ernst, J.F.2
  • 11
    • 0035724309 scopus 로고    scopus 로고
    • Distinct and redundant roles of the two protein kinase a isoforms tpk1p and tpk2p in morphogenesis and growth of candida albicans
    • Bockmuhl DP, Krishnamurthy S, Gerads M, Sonneborn A, Ernst JF (2001). Distinct and redundant roles of the two protein kinase A isoforms Tpk1p and Tpk2p in morphogenesis and growth of Candida albicans. Mol Microbiol 42, 1243-1257.
    • (2001) Mol Microbiol , vol.42 , pp. 1243-1257
    • Bockmuhl, D.P.1    Krishnamurthy, S.2    Gerads, M.3    Sonneborn, A.4    Ernst, J.F.5
  • 12
    • 0035399946 scopus 로고    scopus 로고
    • Virulence factors of candida albicans
    • Calderone RA, Fonzi WA (2001). Virulence factors of Candida albicans. Trends Microbiol 9, 327-335.
    • (2001) Trends Microbiol , vol.9 , pp. 327-335
    • Calderone, R.A.1    Fonzi, W.A.2
  • 13
    • 84863057823 scopus 로고    scopus 로고
    • Rhb1 regulates the expression of secreted aspartic protease 2 through the tor signaling pathway in candida albicans
    • Chen YT, Lin CY, Tsai PW, Yang CY, Hsieh WP, Lan CY (2012). Rhb1 regulates the expression of secreted aspartic protease 2 through the TOR signaling pathway in Candida albicans. Eukaryotic Cell 11, 168-182.
    • (2012) Eukaryotic Cell , vol.11 , pp. 168-182
    • Chen, Y.T.1    Lin, C.Y.2    Tsai, P..W.3    Yang, C.Y.4    Hsieh, W.P.5    Lan, C.Y.6
  • 15
    • 0036961514 scopus 로고    scopus 로고
    • Candida albicans mds3p, a conserved regulator of ph responses and virulence identified through insertional mutagenesis
    • Davis DA, Bruno VM, Loza L, Filler SG, Mitchell AP (2002). Candida albicans Mds3p, a conserved regulator of pH responses and virulence identified through insertional mutagenesis. Genetics 162, 1573-1581.
    • (2002) Genetics , vol.162 , pp. 1573-1581
    • Davis, D.A.1    Bruno, V.M.2    Loza, L.3    Filler, S.G.4    Mitchell, A.P.5
  • 16
    • 36849075751 scopus 로고    scopus 로고
    • Farnesol and dodecanol effects on the candida albicans ras1-camp signalling pathway and the regulation of morphogenesis
    • Davis-Hanna A, Piispanen AE, Stateva LI, Hogan DA (2008). Farnesol and dodecanol effects on the Candida albicans Ras1-cAMP signalling pathway and the regulation of morphogenesis. Mol Microbiol 67, 47-62.
    • (2008) Mol Microbiol , vol.67 , pp. 47-62
    • Davis-Hanna, A.1    Piispanen, A.E.2    Stateva, L.I.3    Hogan, D.A.4
  • 17
    • 32944472993 scopus 로고    scopus 로고
    • The cek1 and hog1 mitogen-activated protein kinases play complementary roles in cell wall biogenesis and chlamydospore formation in the fungal pathogen candida albicans
    • Eisman B, Alonso-Monge R, Roman E, Arana D, Nombela C, Pla J (2006). The Cek1 and Hog1 mitogen-activated protein kinases play complementary roles in cell wall biogenesis and chlamydospore formation in the fungal pathogen Candida albicans. Eukaryotic Cell 5, 347-358.
    • (2006) Eukaryotic Cell , vol.5 , pp. 347-358
    • Eisman, B.1    Alonso-Monge, R.2    Roman, E.3    Arana, D.4    Nombela, C.5    Pla, J.6
  • 18
    • 31944434598 scopus 로고    scopus 로고
    • Role of the hog1 stress-activated protein kinase in the global transcriptional response to stress in the fungal pathogen candida albicans
    • Enjalbert B, Smith DA, Cornell MJ, Alam I, Nicholls S, Brown AJ, Quinn J (2006). Role of the Hog1 stress-activated protein kinase in the global transcriptional response to stress in the fungal pathogen Candida albicans. Mol Biol Cell 17, 1018-1032.
    • (2006) Mol Biol Cell , vol.17 , pp. 1018-1032
    • Enjalbert, B.1    Smith, D.A.2    Cornell, M.J.3    Alam, I.4    Nicholls, S.5    Brown, A.J.6    Quinn, J.7
  • 19
    • 0032692954 scopus 로고    scopus 로고
    • Ras signaling is required for serum-induced hyphal differentiation in candida albicans
    • Feng Q, Summers E, Guo B, Fink G (1999). Ras signaling is required for serum-induced hyphal differentiation in Candida albicans. J Bacteriol 181, 6339-6346.
    • (1999) J Bacteriol , vol.181 , pp. 6339-6346
    • Feng, Q.1    Summers, E.2    Guo, B.3    Fink, G.4
  • 20
    • 0027192868 scopus 로고
    • Isogenic strain construction and gene mapping in candida albicans
    • Fonzi WA, Irwin MY (1993). Isogenic strain construction and gene mapping in Candida albicans. Genetics 134, 717-728.
    • (1993) Genetics , vol.134 , pp. 717-728
    • Fonzi, W.A.1    Irwin, M.Y.2
  • 21
    • 62549113091 scopus 로고    scopus 로고
    • Nitrogen catabolite repression-sensitive transcription as a readout of tor pathway regulation: The genetic background, reporter gene and gata factor assayed determine the outcomes
    • Georis I, Feller A, Tate JJ, Cooper TG, Dubois E (2009). Nitrogen catabolite repression-sensitive transcription as a readout of Tor pathway regulation: the genetic background, reporter gene and GATA factor assayed determine the outcomes. Genetics 181, 861-874.
    • (2009) Genetics , vol.181 , pp. 861-874
    • Georis, I.1    Feller, A.2    Tate, J.J.3    Cooper, T.G.4    Dubois, E.5
  • 22
    • 82555169608 scopus 로고    scopus 로고
    • Candida albicans developmental regulation: Adenylyl cyclase as a coincidence detector of parallel signals
    • Hogan DA, Muhlschlegel FA (2011). Candida albicans developmental regulation: adenylyl cyclase as a coincidence detector of parallel signals. Curr Opin Microbiol 14, 682-686.
    • (2011) Curr Opin Microbiol , vol.14 , pp. 682-686
    • Hogan, D.A.1    Muhlschlegel, F.A.2
  • 23
    • 74249093221 scopus 로고    scopus 로고
    • A phenotypic profile of the candida albicans regulatory network
    • Homann OR, Dea J, Noble SM, Johnson AD (2009). A phenotypic profile of the Candida albicans regulatory network. PLoS Genet 5, e1000782.
    • (2009) PLoS Genet , vol.5
    • Homann, O.R.1    Dea, J.2    Noble, S.M.3    Johnson, A.D.4
  • 25
    • 0030760722 scopus 로고    scopus 로고
    • Two protein-tyrosine phosphatases inactivate the osmotic stress response pathway in yeast by targeting the mitogen-activated protein kinase, hog1
    • Jacoby T, Flanagan H, Faykin A, Seto AG, Mattison C, Ota I (1997). Two protein-tyrosine phosphatases inactivate the osmotic stress response pathway in yeast by targeting the mitogen-activated protein kinase, Hog1. J Biol Chem 272, 17749-17755.
    • (1997) J Biol Chem , vol.272 , pp. 17749-17755
    • Jacoby, T.1    Flanagan, H.2    Faykin, A.3    Seto, A.G.4    Mattison, C.5    Ota, I.6
  • 26
    • 27844459081 scopus 로고    scopus 로고
    • Fungal adenylyl cyclase integrates co2 sensing with camp signaling and virulence
    • Klengel T et al. (2005). Fungal adenylyl cyclase integrates CO2 sensing with cAMP signaling and virulence. Curr Biol 15, 2021-2026.
    • (2005) Curr Biol , vol.15 , pp. 2021-2026
    • Klengel, T.1
  • 27
    • 0029832793 scopus 로고    scopus 로고
    • Candida albicans strains heterozygous and homozygous for mutations in mitogen-activated protein kinase signaling components have defects in hyphal development
    • Kohler JR, Fink GR (1996). Candida albicans strains heterozygous and homozygous for mutations in mitogen-activated protein kinase signaling components have defects in hyphal development. Proc Natl Acad Sci USA 93, 13223-13228.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13223-13228
    • Kohler, J.R.1    Fink, G.R.2
  • 28
    • 0035966045 scopus 로고    scopus 로고
    • Dna array studies demonstrate convergent regulation of virulence factors by cph1, cph2, and efg1 in candida albicans
    • Lane S, Birse C, Zhou S, Matson R, Liu H (2001). DNA array studies demonstrate convergent regulation of virulence factors by Cph1, Cph2, and Efg1 in Candida albicans. J Biol Chem 276, 48988-48996.
    • (2001) J Biol Chem , vol.276 , pp. 48988-48996
    • Lane, S.1    Birse, C.2    Zhou, S.3    Matson, R.4    Liu, H.5
  • 30
    • 83455177213 scopus 로고    scopus 로고
    • Target of rapamycin ( tor) in nutrient signaling and growth control
    • Loewith R, Hall MN (2011). Target of rapamycin (TOR) in nutrient signaling and growth control. Genetics 189, 1177-1201.
    • (2011) Genetics , vol.189 , pp. 1177-1201
    • Loewith, R.1    Hall, M.N.2
  • 31
    • 84861205961 scopus 로고    scopus 로고
    • A gata transcription factor recruits hda1 in response to reduced tor 1 signaling to establish a hyphal chromatin state in candida albicans
    • Lu Y, Su C, Liu H (2012). A GATA transcription factor recruits Hda1 in response to reduced Tor1 signaling to establish a hyphal chromatin state in Candida albicans. PLoS Pathog 8, e1002662.
    • (2012) PLoS Pathog , vol.8
    • Lu, Y.1    Su, C.2    Liu, H.3
  • 32
    • 57349156700 scopus 로고    scopus 로고
    • Efg1-mediated recruitment of nua4 to promoters is required for hypha-specific swi/snf binding and activation in candida albicans
    • Lu Y, Su C, Mao X, Raniga PP, Liu H, Chen J (2008). Efg1-mediated recruitment of NuA4 to promoters is required for hypha-specific Swi/Snf binding and activation in Candida albicans. Mol Biol Cell 19, 4260-4272.
    • (2008) Mol Biol Cell , vol.19 , pp. 4260-4272
    • Lu, Y.1    Su, C.2    Mao, X.3    Raniga, P.P.4    Liu, H.5    Chen, J.6
  • 33
    • 79960921059 scopus 로고    scopus 로고
    • Hyphal development in candida albicans requires two temporally linked changes in promoter chromatin for initiation and maintenance
    • Lu Y, Su C, Wang A, Liu H (2011). Hyphal development in Candida albicans requires two temporally linked changes in promoter chromatin for initiation and maintenance. PLoS Biol 9, e1001105.
    • (2011) PLoS Biol , vol.9
    • Lu, Y.1    Su, C.2    Wang, A.3    Liu, H.4
  • 34
    • 0028228109 scopus 로고
    • A two-component system that regulates an osmosensing map kinase cascade in yeast
    • Maeda T, Wurgler-Murphy SM, Saito H (1994). A two-component system that regulates an osmosensing MAP kinase cascade in yeast. Nature 369, 242-245.
    • (1994) Nature , vol.369 , pp. 242-245
    • Maeda, T.1    Wurgler-Murphy, S.M.2    Saito, H.3
  • 35
    • 26244442243 scopus 로고    scopus 로고
    • Protein phosphatases in mapk signalling: We keep learning from yeast
    • Martin H, Flandez M, Nombela C, Molina M (2005). Protein phosphatases in MAPK signalling: we keep learning from yeast. Mol Microbiol 58, 6-16.
    • (2005) Mol Microbiol , vol.58 , pp. 6-16
    • Martin, H.1    Flandez, M.2    Nombela, C.3    Molina, M.4
  • 37
    • 0036203303 scopus 로고    scopus 로고
    • Conserved serine/threonine kinase encoded by cbk1 regulates expression of several hypha-associated transcripts and genes encoding cell wall proteins in candida albicans
    • McNemar MD, Fonzi WA (2002). Conserved serine/threonine kinase encoded by CBK1 regulates expression of several hypha-associated transcripts and genes encoding cell wall proteins in Candida albicans. J Bacteriol 184, 2058-2061.
    • (2002) J Bacteriol , vol.184 , pp. 2058-2061
    • McNemar, M.D.1    Fonzi, W.A.2
  • 38
    • 0029089795 scopus 로고
    • Pyp1 and pyp2 ptpases dephosphorylate an osmosensing map kinase controlling cell size at division in fission yeast
    • Millar JB, Buck V, Wilkinson MG (1995). Pyp1 and Pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell size at division in fission yeast. Genes Dev 9, 2117-2130.
    • (1995) Genes Dev , vol.9 , pp. 2117-2130
    • Millar, J.B.1    Buck, V.2    Wilkinson, M.G.3
  • 39
    • 0036798450 scopus 로고    scopus 로고
    • Transcription profiling of candida albicans cells undergoing the yeast-to-hyphal transition
    • Nantel A et al. (2002). Transcription profiling of Candida albicans cells undergoing the yeast-to-hyphal transition. Mol Biol Cell 13, 3452-3465.
    • (2002) Mol Biol Cell , vol.13 , pp. 3452-3465
    • Nantel, A.1
  • 40
    • 77954095162 scopus 로고    scopus 로고
    • Systematic screens of a candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity
    • Noble SM, French S, Kohn LA, Chen V, Johnson AD (2010). Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity. Nat Genet 42, 590-598.
    • (2010) Nat Genet , vol.42 , pp. 590-598
    • Noble, S.M.1    French, S.2    Kohn, L.A.3    Chen, V.4    Johnson, A.D.5
  • 42
    • 35748973557 scopus 로고    scopus 로고
    • Tor signalling regulates mitotic commitment through the stress map kinase pathway and the polo and cdc2 kinases
    • Petersen J, Nurse P (2007). TOR signalling regulates mitotic commitment through the stress MAP kinase pathway and the Polo and Cdc2 kinases. Nat Cell Biol 9, 1263-1272.
    • (2007) Nat Cell Biol , vol.9 , pp. 1263-1272
    • Petersen, J.1    Nurse, P.2
  • 43
    • 0032796422 scopus 로고    scopus 로고
    • Prr1, a homolog of aspergillus nidulans palf, controls ph-dependent gene expression and filamentation in candida albicans
    • Porta A, Ramon AM, Fonzi WA (1999). PRR1, a homolog of Aspergillus nidulans palF, controls pH-dependent gene expression and filamentation in Candida albicans. J Bacteriol 181, 7516-7522.
    • (1999) J Bacteriol , vol.181 , pp. 7516-7522
    • Porta, A.1    Ramon, A.M.2    Fonzi, W.A.3
  • 44
    • 0035282906 scopus 로고    scopus 로고
    • Regulation of the sko1 transcriptional repressor by the hog1 map kinase in response to osmotic stress
    • Proft M, Pascual-Ahuir A, de Nadal E, Arino J, Serrano R, Posas F (2001). Regulation of the Sko1 transcriptional repressor by the Hog1 MAP kinase in response to osmotic stress. EMBO J 20, 1123-1132.
    • (2001) EMBO J , vol.20 , pp. 1123-1132
    • Proft, M.1    Pascual-Ahuir, A.2    De Nadal, E.3    Arino, J.4    Serrano, R.5    Posas, F.6
  • 45
    • 0032933350 scopus 로고    scopus 로고
    • Repressors and upstream repressing sequences of the stress-regulated ena1 gene in saccharomyces cerevisiae: Bzip protein sko1p confers hog-dependent osmotic regulation
    • Proft M, Serrano R (1999). Repressors and upstream repressing sequences of the stress-regulated ENA1 gene in Saccharomyces cerevisiae: bZIP protein Sko1p confers HOG-dependent osmotic regulation. Mol Cell Biol 19, 537-546.
    • (1999) Mol Cell Biol , vol.19 , pp. 537-546
    • Proft, M.1    Serrano, R.2
  • 46
    • 0036289351 scopus 로고    scopus 로고
    • Hog1 kinase converts the sko1-cyc8-tup1 repressor complex into an activator that recruits saga and swi/snf in response to osmotic stress
    • Proft M, Struhl K (2002). Hog1 kinase converts the Sko1-Cyc8-Tup1 repressor complex into an activator that recruits SAGA and SWI/SNF in response to osmotic stress. Mol Cell 9, 1307-1317.
    • (2002) Mol Cell , vol.9 , pp. 1307-1317
    • Proft, M.1    Struhl, K.2
  • 47
    • 0032805716 scopus 로고    scopus 로고
    • Effect of environmental ph on morphological development of candida albicans is mediated via the pacc-related transcription factor encoded by prr2
    • Ramon AM, Porta A, Fonzi WA (1999). Effect of environmental pH on morphological development of Candida albicans is mediated via the PacC-related transcription factor encoded by PRR2. J Bacteriol 181, 7524-7530.
    • (1999) J Bacteriol , vol.181 , pp. 7524-7530
    • Ramon, A.M.1    Porta, A.2    Fonzi, W.A.3
  • 49
    • 0034971791 scopus 로고    scopus 로고
    • The saccharomyces cerevisiae sko1p transcription factor mediates hog pathway-dependent osmotic regulation of a set of genes encoding enzymes implicated in protection from oxidative damage
    • Rep M, Proft M, Remize F, Tamas M, Serrano R, Thevelein JM, Hohmann S (2001). The Saccharomyces cerevisiae Sko1p transcription factor mediates HOG pathway-dependent osmotic regulation of a set of genes encoding enzymes implicated in protection from oxidative damage. Mol Microbiol 40, 1067-1082.
    • (2001) Mol Microbiol , vol.40 , pp. 1067-1082
    • Rep, M.1    Proft, M.2    Remize, F.3    Tamas, M.4    Serrano, R.5    Thevelein, J.M.6    Hohmann, S.7
  • 50
    • 5044225522 scopus 로고    scopus 로고
    • The sat1 flipper, an optimized tool for gene disruption in candida albicans
    • Reuss O, Vik A, Kolter R, Morschhauser J (2004). The SAT1 flipper, an optimized tool for gene disruption in Candida albicans. Gene 341, 119-127.
    • (2004) Gene , vol.341 , pp. 119-127
    • Reuss, O.1    Vik, A.2    Kolter, R.3    Morschhauser, J.4
  • 52
    • 42149083876 scopus 로고    scopus 로고
    • Nutritional control via tor signaling in saccharomyces cerevisiae
    • Rohde JR, Bastidas R, Puria R, Cardenas ME (2008). Nutritional control via Tor signaling in Saccharomyces cerevisiae. Curr Opin Microbiol 11, 153-160.
    • (2008) Curr Opin Microbiol , vol.11 , pp. 153-160
    • Rohde, J.R.1    Bastidas, R.2    Puria, R.3    Cardenas, M.E.4
  • 53
    • 0042322392 scopus 로고    scopus 로고
    • Nutrient signaling through tor kinases controls gene expression and cellular differentiation in fungi
    • Rohde JR, Cardenas ME (2004). Nutrient signaling through TOR kinases controls gene expression and cellular differentiation in fungi. Curr Topics Microbiol Immunol 279, 53-72.
    • (2004) Curr Topics Microbiol Immunol , vol.279 , pp. 53-72
    • Rohde, J.R.1    Cardenas, M.E.2
  • 55
    • 4344587177 scopus 로고    scopus 로고
    • A conserved stress-activated protein kinase regulates a core stress response in the human pathogen candida albicans
    • Smith DA, Nicholls S, Morgan BA, Brown AJ, Quinn J (2004). A conserved stress-activated protein kinase regulates a core stress response in the human pathogen Candida albicans. Mol Biol Cell 15, 4179-4190.
    • (2004) Mol Biol Cell , vol.15 , pp. 4179-4190
    • Smith, D.A.1    Nicholls, S.2    Morgan, B.A.3    Brown, A.J.4    Quinn, J.5
  • 57
    • 0037507285 scopus 로고    scopus 로고
    • Haploinsufficiency-based large-scale forward genetic analysis of filamentous growth in the diploid human fungal pathogen c. Albicans
    • Uhl MA, Biery M, Craig N, Johnson AD (2003). Haploinsufficiency-based large-scale forward genetic analysis of filamentous growth in the diploid human fungal pathogen C. albicans. EMBO J 22, 2668-2678.
    • (2003) EMBO J , vol.22 , pp. 2668-2678
    • Uhl, M.A.1    Biery, M.2    Craig, N.3    Johnson, A.D.4
  • 58
    • 0026445510 scopus 로고
    • Acr1, a yeast atf/creb repressor
    • Vincent AC, Struhl K (1992). ACR1, a yeast ATF/CREB repressor. Mol Cell Biol 12, 5394-5405.
    • (1992) Mol Cell Biol , vol.12 , pp. 5394-5405
    • Vincent, A.C.1    Struhl, K.2
  • 59
    • 67651173120 scopus 로고    scopus 로고
    • Identifying infection-associated genes of candida albicans in the postgenomic era
    • Wilson D et al. (2009). Identifying infection-associated genes of Candida albicans in the postgenomic era. FEMS Yeast Res 9, 688-700.
    • (2009) FEMS Yeast Res , vol.9 , pp. 688-700
    • Wilson, D.1
  • 60
    • 0033028595 scopus 로고    scopus 로고
    • Rapid hypothesis testing with candida albicans through gene disruption with short homology regions
    • Wilson RB, Davis D, Mitchell AP (1999). Rapid hypothesis testing with Candida albicans through gene disruption with short homology regions. J Bacteriol 181, 1868-1874.
    • (1999) J Bacteriol , vol.181 , pp. 1868-1874
    • Wilson, R.B.1    Davis, D.2    Mitchell, A.P.3
  • 61
    • 3943093972 scopus 로고    scopus 로고
    • Nosocomial bloodstream infections in us hospitals: Analysis of 24,179 cases from a prospective nationwide surveillance study
    • Wisplinghoff H, Bischoff T, Tallent SM, Seifert H, Wenzel RP, Edmond MB (2004). Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Clin Infect Dis 39, 309-317.
    • (2004) Clin Infect Dis , vol.39 , pp. 309-317
    • Wisplinghoff, H.1    Bischoff, T.2    Tallent, S.M.3    Seifert, H.4    Wenzel, R.P.5    Edmond, M.B.6
  • 62
    • 0031027466 scopus 로고    scopus 로고
    • Regulation of the saccharomyces cerevisiae hog1 mitogen-activated protein kinase by the ptp2 and ptp3 protein tyrosine phosphatases
    • Wurgler-Murphy SM, Maeda T, Witten EA, Saito H (1997). Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein kinase by the PTP2 and PTP3 protein tyrosine phosphatases. Mol Cell Biol 17, 1289-1297.
    • (1997) Mol Cell Biol , vol.17 , pp. 1289-1297
    • Wurgler-Murphy, S.M.1    Maeda, T.2    Witten, E.A.3    Saito, H.4
  • 63
    • 46749132932 scopus 로고    scopus 로고
    • Bacterial peptidoglycan triggers candida albicans hyphal growth by directly activating the adenylyl cyclase cyr1p
    • Xu XL, Lee RT, Fang HM, Wang YM, Li R, Zou H, Zhu Y, Wang Y (2008). Bacterial peptidoglycan triggers Candida albicans hyphal growth by directly activating the adenylyl cyclase Cyr1p. Cell Host Microbe 4, 28-39.
    • (2008) Cell Host Microbe , vol.4 , pp. 28-39
    • Xu, X.L.1    Lee, R.T.2    Fang, H.M.3    Wang, Y.M.4    Li, R.5    Zou, H.6    Zhu, Y.7    Wang, Y.8
  • 64
    • 77954364299 scopus 로고    scopus 로고
    • Mds3 regulates morphogenesis in candida albicans through the tor pathway
    • Zacchi LF, Gomez-Raja J, Davis DA (2010). Mds3 regulates morphogenesis in Candida albicans through the TOR pathway. Mol Cell Biol 30, 3695-3710.
    • (2010) Mol Cell Biol , vol.30 , pp. 3695-3710
    • Zacchi, L.F.1    Gomez-Raja, J.2    Davis, D.A.3
  • 65
    • 0030820725 scopus 로고    scopus 로고
    • Differential regulation of fus3 map kinase by tyrosine-specific phosphatases ptp2/ptp3 and dual-specificity phosphatase msg5 in saccharomyces cerevisiae
    • Zhan XL, Deschenes RJ, Guan KL (1997). Differential regulation of FUS3 MAP kinase by tyrosine-specific phosphatases PTP2/PTP3 and dual-specificity phosphatase MSG5 in Saccharomyces cerevisiae. Genes Dev 11, 1690-1702.
    • (1997) Genes Dev , vol.11 , pp. 1690-1702
    • Zhan, X.L.1    Deschenes, R.J.2    Guan, K.L.3
  • 66
    • 75149198375 scopus 로고    scopus 로고
    • Candida albicans cyr1, cap1 and g-actin form a sensor/effector apparatus for activating camp synthesis in hyphal growth
    • Zou H, Fang HM, Zhu Y, Wang Y (2010). Candida albicans Cyr1, Cap1 and G-actin form a sensor/effector apparatus for activating cAMP synthesis in hyphal growth. Mol Microbiol 75, 579-591.
    • (2010) Mol Microbiol , vol.75 , pp. 579-591
    • Zou, H.1    Fang, H.M.2    Zhu, Y.3    Wang, Y.4


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