Light fractionated ALA-PDT enhances therapeutic efficacy in vitro; The influence of PpIX concentration and illumination parameters

Photochemical and Photobiological Sciences

Volumn 12, Issue 2, 2013, Pages 241-245

  De Bruijn, Henriëtte S ^a   Casas, Adriana G ^b   Di Venosa, Gabriela ^b   Gandara, Lautato ^b   Sterenborg, Henricus J C M ^a   Batlle, Alcira ^b   Robinson, Dominic J ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b Centro de Investigaciones sobre Porfirinas y Porfirias   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOLEVULINIC ACID; PHOTOSENSITIZING AGENT;

ANIMAL; ARTICLE; CELL LINE; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECT; LIGHT; MOUSE; PHOTOCHEMOTHERAPY; STRUCTURE ACTIVITY RELATION;

AMINOLEVULINIC ACID; ANIMALS; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; LIGHT; MICE; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; STRUCTURE-ACTIVITY RELATIONSHIP;

MLCS; MLOWN;

EID: 84873326941     PISSN: 1474905X     EISSN: 14749092     Source Type: Journal    
DOI: 10.1039/c2pp25287b     Document Type: Article

References (30)

1. H. C. de Vijlder H. J. C. M. Sterenborg H. A. M. Neumann D. J. Robinson E. R. M. de Haas Light fractionation significantly improves the response of superficial basal cell carcinoma to ALA-PDT: five-year follow-up of a randomized, prospective trial Acta Dermatol. Venerol. 2012 92 641 647
2. E. Sotiriou Z. Apalla E. Chovarda C. Goussi A. Trigoni D. Ioannides Single vs. fractionated photodynamic therapy for face and scalp actinic keratoses: a randomized, intraindividual comparison trial with 12-month follow-up J. Eur. Acad. Dermatol. Venereol. 2012 26 36 40
3. D. J. Robinson H. S. de Bruijn W. M. Star H. J. C. M. Sterenborg Dose and timing of the first light fraction in two fold illumination schemes for topical ALA-mediated photodynamic therapy of hairless mouse skin Photochem. Photobiol. 2003 77 319 323
4. N. van der Veen H. L. L. M. van Leengoed W. M. Star In vivo fluorescence kinetics and photodynamic therapy using 5-aminolevulinic acid-induced porphyrin: increased damage after multiple irradiations Br. J. Cancer 1994 70 867 872
5. H. S. de Bruijn N. van der Veen D. J. Robinson W. M. Star Improvement of systemic 5-aminolevulinic acid-based photodynamic therapy in vivo using light fractionation with a 75 minute interval Cancer Res. 1999 59 901 904
6. N. van der Veen K. M. Hebeda H. S. de Bruijn W. M. Star Photodynamic effectiveness and vasoconstriction in hairless mouse skin after topical 5-aminolevulinic acid and single or two-fold illumination Photochem. Photobiol. 1999 70 921 929
7. N. van der Veen H. S. de Bruijn W. M. Star Photobleaching during and re-appearance after photodynamic therapy of topical ALA-induced fluorescence in UVB-treated mouse skin Int. J. Cancer 1997 72 110 118
8. A. Orenstein G. Kostenich Z. Malik The kinetics of protoporphyrin fluorescence during ALA-PDT in human malignant skin tumors Cancer Lett. 1997 120 229 234
9. C. af Klintenberg A. M. K. Enejder I. Wang S. Andersson-Engels S. Svanberg K. Svandberg Kinetic fluorescence studies of 5-aminolaevulinic acid-induced protoporphyrin IX accumulation in basal cell carcinomas J. Photochem. Photobiol., B 1999 49 120 128
10. H. S. de Bruijn B. Kruijt A. van der Ploeg-van den Heuvel H. J. C. M. Sterenborg D. J. Robinson Increase in protoporphyrin IX after 5-aminolevulinic based photodynamic therapy is due to local resynthesis Photochem. Photobiol. Sci. 2007 6 857 864
11. D. J. Robinson H. S. de Bruijn J. de Wolf H. J. C. M. Sterenborg W. M. Star Topical 5-aminolevulinic acid-photodynamic therapy of hairless mouse skin using two-fold illumination schemes: PpIX fluorescence kinetics, photobleaching and biological effect Photochem. Photobiol. 2000 72 794 802
12. H. S. de Bruijn A. van der Ploeg-van den Heuvel H. J. C. M. Sterenborg D. J. Robinson Fractionated illumination after topical application of 5-aminolevulinic acid on normal skin of hairless mice: the influence of the dark interval J. Photochem. Photobiol., B 2006 85 184 190
13. T. A. Middelburg F. van Zaane H. S. de Bruijn A. van der Ploeg-van den Heuvel H. J. C. M. Sterenborg H. A. M. Neumann E. R. M. de Haas D. J. Robinson Fractionated illumination at low fluence rate photodynamic therapy in mice Photochem. Photobiol. 2010 86 1140 1146
14. S. H. Yuspa P. Hawley-Nelson B. Koehler J. R. Stanley A survey of transformation markers in differentiating epidermal cell lines Cancer Res. 1980 40 4694 4703
15. C. Perotti H. Fukuda G. DiVenosa A. J. MacRobert A. Batlle A. Casas Porphyrin synthesis from ALA derivatives for photodynamic therapy, in vitro and in vivo studies Br. J. Cancer 2004 90 1660 1665
16. Z. Ji G. Yang V. Vasovic B. Cunderlikova Z. Suo J. M. Nesland Q. Peng Subcellular localization pattern of protoporphyrin IX is an important determinant for its photodynamic efficiency of human carcinoma and normal cell lines J. Photochem. Photobiol., B 2006 84 213 220
17. M. J. Niedre A. J. Secord M. S. Patterson B. C. Wilson In vitro tests of the validity of singlet oxygen luminescence measurements as a dose metric in photodynamic therapy Cancer Res. 2003 63 7986 7994
18. S. Correa Garcia A. Casas C. Perotti A. Batlle M. Bermudez Morreti Mechanistic studies on δ-aminolevulinic acid uptake and efflux in a mammary adenocarcinoma cell line Br. J. Cancer 2003 89 173 177
19. B. J. Wilson M. Olivo G. Singh Subcellular localization of photofrin and aminolevulinic acid and photodynamic cross-resistance in vitro in radiation-induced fibrosarcoma cells sensitive or resistant to photofrin mediated photodynamic therapy Photochem. Photobiol. 1997 65 166 176
20. D. Grebenova K. Kuzelova K. Smetana M. Pluskalova H. Cajthamlova I. Marinov O. Fuchs J. Soucek P. Jarolim Z. Hrkal Mitochondrial and endoplasmic reticulum stress-induced apoptotic pathways are activated by 5-aminolevulinic acid-based photodynamic therapy in HL60 leukemia cells J. Photochem. Photobiol., B 2003 69 71 85
21. J. Moan On the diffusion length of singlet oxygen in cells and tissues J. Photochem. Photobiol., B 1990 6 343 344
22. S. K. Bisland E. A. Goebel N. S. Hassanali C. Johnson B. C. Wilson Increased expression of mitochondrial benzodiazepine receptors following low-level light treatment facilitates enhanced protoporphyrin IX production in glioma-derived cells in vitro Lasers Surg. Med. 2007 39 678 684
23. T. Kriska W. Korytowski A. W. Girotti Role of mitochondrial cardiolipin peroxidation in apoptotic photokilling of 5-aminolevulinate-treated tumor cells Arch. Biochem. Biophys. 2005 433 435 446
24. N. L. Oleinick R. L. Morris I. Belinchenko The role of apoptosis in response to photodynamic therapy: what where why and how Photochem. Photobiol. Sci. 2002 1 1 21
25. D. Kessel M. G. Vicente J. J. Reiners Initiation of apoptosis and autophagy by photodynamic therapy Lasers Surg. Med. 2006 38 482 488
26. E. Buyaert M. Dewaele P. Agostinis Molecular effectors of multiple cell death pathways initiated by photodynamic therapy Biochim. Biophys. Acta 2007 1776 86 107
27. H. T. Ji L. T. Chen Y. H. Lin H. F. Chien C. H. Chen 5-ALA mediated photodynamic therapy induces autophagic cell death via the AMP-activated protein kinase Mol. Cancer 2010 9 91
28. I. Coupienne S. Bontems M. Dewaele N. Rubio Y. Habraken S. Fulda P. Agostinis J. Piette NF-kappaB inhibition improves the sensitivity of human glioblastoma cells to 5-aminolevulinic acid-based photodynamic therapy Biochem. Pharmacol. 2011 81 606 616
29. E. R. M. de Haas H. S. de Bruijn H. J. C. M. Sterenborg H. A. M. Neumann D. J. Robinson Microscopic distribution of protoporphyrin IX (PpIX) fluorescence in superficial basal cell carcinoma during light fractionated aminolevulinic acid photodynamic therapy Acta Dermatol. Venerol. 2008 88 547 554
30. H. S. de Bruijn E. R. M. de Haas K. M. Hebeda A. van der Ploeg-van den Heuvel H. J. C. M. Sterenborg H. A. M. Neumann D. J. Robinson Light fractionation does not enhance the efficacy of methyl 5-aminolevulinate mediated photodynamic therapy in normal mouse skin Photochem. Photobiol. Sci. 2007 6 1325 1331