Effects of cytoprotective antioxidants on lymphocytes from representative mitochondrial neurodegenerative diseases

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 4, 2013, Pages 969-978

  Goldschmidt, Ruth ^a   Arce, Pablo M ^a   Khdour, Omar M ^a   Collin, Valérie C ^a   Dey, Sriloy ^a   Jaruvangsanti, Jennifer ^a   Fash, David M ^a   Hecht, Sidney M ^a  

^a ARIZONA STATE UNIVERSITY   (United States)

Author keywords

Adenosine triphosphate; Antioxidants; Electron transport chain; Mitochondrial dysfunction; Reactive oxygen species

Indexed keywords

2 (N,N DIMETHYLAMINO) 4 HEXADECYL 6 METHYLPYRIMIDIN 5 OL; 4 DECYL 2 (N,N DIMETHYLAMINO) 6 METHYLPYRIMIDIN 5 OL; ADENOSINE TRIPHOSPHATE; ANTIOXIDANT; CATENA; DECYLUBIQUINONE; IDEBENONE; IDEBENONE DERIVATIVE; PYRIMIDINOL DERIVATIVE; REACTIVE OXYGEN METABOLITE; UBIDECARENONE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROTECTION; CELL STRESS; CONTROLLED STUDY; DEGENERATIVE DISEASE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRON TRANSPORT; HUMAN; HUMAN CELL; LIPOPHILICITY; LYMPHOCYTE; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIOXIDANTS; CATTLE; CELL LINE; CELL SURVIVAL; DRUG DESIGN; GLUTATHIONE; HUMANS; LYMPHOCYTES; MITOCHONDRIA; MULTIENZYME COMPLEXES; NADH, NADPH OXIDOREDUCTASES; NEURODEGENERATIVE DISEASES; NEUROPROTECTIVE AGENTS; PYRIMIDINES; REACTIVE OXYGEN SPECIES; UBIQUINONE;

EID: 84873322437     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2012.11.051     Document Type: Article

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