Functional role of scaffold geometries as a template for physiological ECM formation: Evaluation of collagen 3D assembly

Journal of Tissue Engineering and Regenerative Medicine

Volumn 7, Issue 2, 2013, Pages 161-168

  Stoppato, M ^a,b   Carletti, E ^a,b   Maniglio, D ^a,b,c   Migliaresi, C ^a,b,c   Motta, A ^a,b,c  

^a UNIVERSITY OF TRENTO   (Italy)

^b European Institute of Excellence on Tissue Engineering and Regenerative Medicine   (Italy)

^c Research Unit of Trento   (Italy)

Author keywords

Biomimetic material; Bone tissue engineering; Collagen; Image analysis; Osteoblast; Scaffold

Indexed keywords

BIOMIMETIC MATERIALS; BIOMIMETICS; BONE; CELL CULTURE; CELL PROLIFERATION; LACTIC ACID; PHYSIOLOGICAL MODELS; SCAFFOLDS (BIOLOGY); TISSUE REGENERATION;

3D ORGANIZATIONS; BONE TISSUE ENGINEERING; BONE TISSUE REGENERATION; CELL ACTIVITY; COLLAGEN FIBRES; ECM FORMATION; FORMATION EVALUATION; HARD TISSUES; IMAGE-ANALYSIS; SCAFFOLD MORPHOLOGY;

COLLAGEN;

COLLAGEN; POLYLACTIC ACID; TISSUE SCAFFOLD;

ARTICLE; CELL ACTIVITY; CELL ADHESION; CELL GROWTH; CELL LINE; CELL MIGRATION; CELL PROLIFERATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; EXTRACELLULAR MATRIX; GEOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LEACHING; MINERALIZATION; MORPHOLOGY; NANOFABRICATION; OSTEOBLAST; OSTEOSARCOMA CELL; POROSITY; PRIORITY JOURNAL; TISSUE ENGINEERING;

EID: 84873308493     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.516     Document Type: Article

References (49)

1. Aydin HM, El Haj AJ, Piåÿkin E, et al. 2009; Improving pore interconnectivity in polymeric scaffolds for tissue engineering. J Tissue Eng Regen Med 3: 470-476.
2. Block JE. 2005; The role and effectiveness of bone marrow in osseous regeneration. Med Hypotheses 65: 740-747.
3. Carletti E, Endogan T, Hasirci N, et al. 2011; Microfabrication of PDLLA scaffolds. J Tissue Eng Regen Med 5: 569-577.
4. Cheng W, Li H, Chang J. 2005; Fabrication and characterization of β-dicalcium silicate/poly(d, l-lactic acid) composite scaffolds. Mater Lett 59: 2214-2218.
5. Daley WP, Peters SB, Larsen M. 2008; Extracellular matrix dynamics in development and regenerative medicine. J Cell Sci 121: 255-264.
6. Dolber PC, Spach MS. 1993; Conventional and confocal fluorescence microscopy of collagen fibers in the heart. J Histochem Cytochem 41: 465-469.
7. Draghi L, Resta S, Pirozzolo MG, et al. 2005; Microspheres leaching for scaffold porosity control. J Mater Sci Mater Med 16: 1093-1097.
8. Eriksson C, Ohlson K, Richter K, et al. 2007; Callus formation and remodeling at titanium implants. J Biomed Mater Res A 83: 1062-1069.
9. Garlotta D. 2002; A literature review of poly(lactic acid). J Polym Environ 9: 63-84.
10. Gerstenfeld LC, Cullinane DM, Barnes GL, et al. 2003; Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation. J Cell Biochem 88: 873-884.
11. Ghosh S, Viana JC, Reis RL, et al. 2008; Development of porous lamellar poly(l-lactic acid) scaffolds by conventional injection molding process. Acta Biomater 4: 887-896.
12. Goegan P, Johnson G, Vincent R. 1995; Effects of serum pand colloid on the Alamar blue arcus biologicals. Toxic In Vitro Assay Cell Cult 9(3): 257-266.
13. Grizzi I, Garreau H, Li S, et al. 1995; Hydrolytic degradation of devices based on poly(dl-lactic acid) size-dependence. Biomaterials 16: 305-311.
14. Guan J, Fujimoto KL, Sacks MS, et al. 2005; Preparation and characterization of highly porous, biodegradable polyurethane scaffolds for soft tissue applications. Biomaterials 26: 3961-3971.
15. Haaparanta AM, Haimi S, Ellä V, et al. 2010; Porous polylactide/β-tricalcium phosphate composite scaffolds for tissue engineering applications. J Tissue Eng Regen Med 4: 366-373.
16. Hollister SJ, Guldberg RE, Kuelske CL, et al. 1996; Relative effects of wound healing and mechanical stimulus on early bone response to porous-coated implants. J Orthop Res 14: 654-662.
17. Hong Z, Reis RL, Mano JF. 2008; Preparation and in vitro characterization of scaffolds of poly(l-lactic acid) containing bioactive glass ceramic nanoparticles. Acta Biomater 4: 1297-1306.
18. Hughes LC, Archer CW, Gwynn I. 2005; The ultrastructure of mouse articular cartilage: collagen orientation and implications for tissue functionality. A polarised light and scanning electron microscope study and review. Eur Cell Mater 9: 68-84.
19. Hsu YY, Gresser JD, Trantolo DJ, et al. 1997; Effect of polymer foam morphology and density on kinetics of in vitro controlled release of isoniazid from compressed foam matrices. J Biomed Mater Res 35: 107-116.
20. Hutmacher DW. 2000; Scaffolds in tissue engineering bone and cartilage. Biomaterials 21: 2529-2543.
21. Ishaug-Riley SL, Crane-Kruger GM, Yaszemski MJ, et al. 1998; Three-dimensional culture of rat calvarial osteoblasts in porous biodegradable polymers. Biomaterials 19: 1405-1412.
22. Jing D, Wu L, Ding J. 2006; Solvent-assisted room-temperature compression molding approach to fabricate porous scaffolds for tissue engineering. Macromol Biosci 6: 747-757.
23. Jones AC, Milthorpe B, Averdunk H, et al. 2004; Analysis of 3D bone ingrowth into polymer scaffolds via micro-computed tomography imaging. Biomaterials 25: 4947-4954.
24. Jones CW, Smolinski D, Keogh A, et al. 2005; Confocal laser scanning microscopy in orthopaedic research. Progr Histochem Cytochem 40: 1-71.
25. Kano M, Masuda Y, Tominaga T, et al. 2001; Collagen synthesis and collagenase activity of cryopreserved heart valves. J Thorac Cardiovasc Surg 122: 706-711.
26. Karageorgiou V, Kaplan D. 2005; Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials 26: 5474-5491.
27. Lamovec J, Mozina E, Baebler B. 2003; Hyperplastic callus formation in osteogenesis imperfecta. Ann Diagn Pathol 7: 231-235.
28. Langer R, Vacanti JP. 1993; Tissue engineering. Science 260: 920-926.
29. Le AX, Miclau T, Hu D, et al. 2001; Molecular aspects of healing in stabilized and non-stabilized fractures. J Orthop Res 19: 78-84.
30. Mandal BB, Kundu SC. 2009; Cell proliferation and migration in silk fibroin 3D scaffolds. Biomaterials 15: 2956-2965.
31. Mckinley T. 2003; Principles of fracture healing. Surgery (Oxf) 21: 209-212.
32. Mikos AG, Thorsen AJ, Czerwonka LA, et al. 1994; Preparation and characterization of poly(l-latic acid) foams. Polymer 35: 1068-1077.
33. O'Brien FJ, Harley BA, Yannas IV, et al. 2005; The effect of pore size on cell adhesion in collagen-GAG scaffolds. Biomaterials 26: 433-441.
34. Oh SH, Park IK, Kim JM, et al. 2006; In vitro and in vivo characteristics of PCL scaffolds with pore size gradient fabricated by a centrifugation method. Biomaterials 28: 1664-1671.
35. Olszta MJ, Cheng X, Jee SS, et al. 2007; Bone structure and formation: A new perspective. Mater Sci Eng 58: 77-116.
36. Othman FS, Li J, Abdullah O, et al. 2007; High resolution/high-contrast MRI of human articular cartilage lesions. Acta Orthop 78: 536-546.
37. Owen TA, Aronow MA, Shalhoub V, et al. 1990; Progressive development of the rat osteoblast phenotype in vitro: reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix. J Cell Physiol 143: 420-430.
38. Schander K, Arvidson K, Mustafa K. 2010; Response of bone and periodontal ligament cells to biodegradable polymer scaffolds in vitro. J Bioact Compat Polym 25: 584-602.
39. Schieker M, Seitz H, Drosse I, et al. 2006; Biomaterials as scaffold for bone tissue engineering. Eur J Trauma 32: 114-124.
40. Schindeler A, Mcdonald MM, Bokko P, et al. 2008; Bone remodeling during fracture repair: the cellular picture. Semin Cell Dev Biol 19: 459-466.
41. Schlichting K, Schell H, Kleemann RU, et al. 2008; Influence of scaffold stiffness on subchondral bone and subsequent cartilage regeneration in an ovine model of osteochondral defect healing. Am J Sports Med 36: 2379-2391.
42. Shefelbine SJ, Augat P, Claes L, et al. 2005; Trabecular bone fracture healing simulation with finite element analysis and fuzzy logic. J Biomech 38: 2440-2450.
43. Spiller KL, Laurencin SJ, Charlton D, et al. 2008; Superporous hydrogels for cartilage repair: evaluation of the morphological and mechanical properties. Acta Biomater 4: 17-25.
44. Sweat F, Puchtler H, Rosenthal SI. 1964; Sirius red F3BA as a stain for connective tissue. Arch Pathol 78: 69-72.
45. Taatjes DJ, Wadsworth MP, Schneider DJ, et al. 2000; Improved quantitative characterization of atherosclerotic plaque composition with immunohistochemistry, confocal fluorescence microscopy, and computer-assisted image analysis. Histochem Cell Biol 113: 161-173.
46. Welsing RTC, van Tienen TG, Ramrattan N, et al. 2008; Effect on tissue differentiation and articular cartilage degradation of a polymer meniscus implant. Am J Sports Med 36: 1978-1989.
47. Zhang RY, Ma PX. 1999; Poly(α-hydroxyl acids)/hydroxyapatite porous composites for bone-tissue engineering. I. Preparation and morphology. J Biomed Mater Res 44: 446-455.
48. Zhu X, Cui W, Li X, et al. 2008; Electrospun fibrous mats with high porosity as potential scaffolds for skin tissue engineering. Biomacromolecules 9: 1795-801.
49. Zeltinger J, Sherwood JK, Graham DA, et al. 2001; Effect of pore size and void fraction on cellular adhesion, proliferation, and matrix deposition. Tissue Eng 7: 557-572.