Poly(α-hydroxyl acids)/hydroxyapatite porous composites for bone- tissue engineering. I. Preparation and morphology

Journal of Biomedical Materials Research

Volumn 44, Issue 4, 1999, Pages 446-455

  Zhang, Ruiyun ^a   Ma, Peter X ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Bone; Composite; Hydroxyapatite; Polymer scaffold; Tissue engineering

Indexed keywords

CARBOXYLIC ACIDS; COMPOSITION EFFECTS; MICROSTRUCTURE; MOLECULAR STRUCTURE; MORPHOLOGY; PHASE SEPARATION; PHOSPHATE MINERALS; PORE SIZE; POROSITY; POROUS MATERIALS; SOLVENTS; THERMAL EFFECTS;

HYDROXYAPATITE; POLYHYDROXYL ACIDS;

BIOMATERIALS;

HYDROXYAPATITE;

ANIMAL TISSUE; ARTICLE; BIODEGRADATION; BONE DENSITY; BONE MINERAL; BONE REMODELING; BONE TISSUE; CELL GROWTH; CELL TRANSPLANTATION; CHEMICAL BOND; FREEZE DRYING; GENETIC ENGINEERING; NONHUMAN; TISSUE REGENERATION;

ADHESIVENESS; BIOCOMPATIBLE MATERIALS; BONE SUBSTITUTES; CHEMISTRY, PHYSICAL; CRYSTALLIZATION; DURAPATITE; FREEZE DRYING; LACTIC ACID; MATERIALS TESTING; MICROSCOPY, ELECTRON, SCANNING; OSMOLAR CONCENTRATION; POLYGLYCOLIC ACID; POLYMERS; POROSITY; SOLVENTS; TEMPERATURE;

EID: 0033559073     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4636(19990315)44:4<446::AID-JBM11>3.0.CO;2-F     Document Type: Article

References (34)

1. Yaszemski M, Payne R, Hayes W, Langer R, Mikos A. Evolution of bone transplantation: Molecular, cellular and tissue strategies to engineer human bone. Biomaterials 1996;17(2): 175-185.
2. Crane G, Ishaug S, Mikos A. Bone tissue engineering. Nat Med 1995;1(12):1322-1324.
3. Vacanti C, Vacanti J. Bone and cartilage reconstruction with tissue engineering approaches. Otolaryngol Clin N Am 1994;27(1):263-276.
4. Ma PX, Langer R. Fabrication of biodegradable polymer foams for cell transplantation and tissue engineering. In: Yarmush M, Morgan J, editors. Tissue engineering. Totowa, New Jersey: Humana Press Inc.; 1998.
5. Mikos AG, Thorsen AJ, Czerwonka LA, Bao Y, Langer R, Winslow DN, Vacanti JP. Preparation and characterization of poly(L-lactic acid) foams. Polymer 1994;35(5):1068-1077.
6. Ma PX, Langer R. Degradation, structure and properties of fibrous nonwoven poly(glycolic acid) scaffolds for tissue engineering. In: Mikos AG, Leong KW, Yaszemski MJ, Tamada JA, Radomsky ML, editors. Polymers in medicine and pharmacy. Materials Research Society; Pittsburgh: 1995. p 99-104.
7. Ma PX, Schloo B, Mooney D, Langer R. Development of biomechanical properties and morphogenesis of in vitro tissue-engineered cartilage. J Biomed Mater Res 1995;29(12):1587-1595.
8. Shinoka T, Ma PX, Shum-Tim D, Breuer CK, Cusick RA, Zund G, Langer R, Vacanti JP, Mayer JE Jr. Tissue-engineered heart valves. Autologous valve leaflet replacement study in a lamb model. Circulation 1996;94(9):164-168.
9. Vert M, Mauduit J, Li S. Biodegradation of PLA/GA polymers: Increasing complexity. Biomaterials 1994;15(15):1209-1213.
10. Akao M, Aoki H, Kato K. Mechanical properties of sintered hydroxyapatite for prosthetic applications. J Mater Sci 1981;16: 809-812.
11. Dewith G, van Dijk HJA, Hattu N, Prijs K. Preparation, micro-structure and mechanical properties of dense polycrystalline hydroxyapatite. J Mater Sci 1981;6:1592-1598.
12. Driessen AA, Klein CP, de Groot K. Preparation and some properties of sintered beta-whitlockite. Biomaterials 1982;3(2): 113-116.
13. Best S, Bonfield W. Processing behaviour of hydroxyapatite powders with contrasting morphology. J Mater Sci: Mater Med 1994;5(8):516-521.
14. Akao M, Sakatsume M, Aoki H, Takagi T, Sasaki S. In vitro mineralization in bovine tooth germ cell cultured with sintered hydroxyapatite. J Mater Sci: Mater Med 1993;4(6):569-574.
15. Puleo DA, Holleran LA, Doremus RH, Bizios R. Osteoblast responses to orthopedic implant materials in vitro. J Biomed Mater Res 1991;25(6):711-723.
16. Klein CP, Patka P, Wolke JG, de Blieck-Hogervorst JM, de Groot K. Long-term in vivo study of plasma-sprayed coatings on titanium alloys of tetracalcium phosphate, hydroxyapatite and alpha-tricalcium phosphate. Biomaterials 1994;15(2):146-150.
17. Jansen JA, van der Waerden JP, Wolke JG. Histologic investigation of the biologic behavior of different hydroxyapatite plasma-sprayed coatings in rabbits. J Biomed Mater Res 1993;27(5):603-610.
18. Higashi S, Yamamuro T, Nakamura T, Ikada Y, Hyon SH, Jamshidi K. Polymer-hydroxyapatite composites for biodegradable bone fillers. Biomaterials 1986;7(3):183-187.
19. Flahiff CM, Blackwell AS, Hollis JM, Feldman DS. Analysis of a biodegradable composite for bone healing. J Biomed Mater Res 1996;32(3):419-424.
20. Verheyen CCPM, Klein CPAT, Blieck-Hogervorst JMAD, Wolke JGC, van Blitterswijn CA. Evaluation of hydroxyapatite/poly(l-lactide) composites: Physico-chemical properties. J Mater Sci: Mater Med 1993;4:58-65.
21. Mikos A, Bao Y, Cima L, Ingber D, Vacanti J, Langer R. Preparation of poly(glycolic acid)-bonded fiber structures for cell attachment and transplantation. J Biomed Mater Res 1993;27(2):183-189.
22. Wintermantel E, Mayer J, Blum J, Eckert KL, Luscher P, Mathey M. Tissue engineering scaffolds using superstructures. Biomaterials 1996;17(2):83-91.
23. Lo H, Ponticiello MS, Leong KW. Fabrication of controlled release biodegradable foams by phase separation. Tiss Eng 1995;1(1):15-28.
24. Schugens C, Maquet V, Grandfils C, Jerome R, Teyssie P. Polylactide macroporous biodegradable implants for cell transplantation. II. Preparation of polylactide foams by liquid-liquid phase separation. J Biomed Mater Res 1996;30(4):449-461.
25. Hsu YY, Gresser JD, Trantolo DJ, Lyons CM, Gangadharam PR, Wise DL. Effect of polymer foam morphology and density on kinetics of in vitro controlled release of isoniazid from compressed foam matrices. J Biomed Mater Res 1997;35(1):107-116.
26. Whinnery LL, Even WR, Beach JV, Loy DA. Engineering the macrostructure of thermally induced phase separated polysilane foams. J Polym Sci, Polym Chem 1996;34:1623-1627.
27. Ravaglioli A, Krajewski A. Bioceramics. London: Chapman & Hall, 1992. 422 p.
28. Shinoka T, Shum-Tim D, Ma PX, Tanel RE, Isogai N, Langer R, Vacanti JP, Mayer JE Jr. Creation of viable pulmonary artery autografts through tissue engineering. J Thorac Cardiovasc Surg 1998;115(3):536-545.
29. Vacanti C, Kim W, Upton J, Vacanti M, Mooney D, Schloo B, Vacanti J. Tissue-engineered growth of bone and cartilage. Transplant Proc 1993;25:1019-1021.
30. Ishaug SL, Crane GM, Miller MJ, Yasko AW, Yaszemski MJ, Mikos AG. Bone formation by three-dimensional stromal osteoblast culture in biodegradable polymer scaffolds. J Biomed Mater Res 1997;36(1):17-28.
31. Cusick RA, Lee H, Sano K, Pollok JM, Utsunomiya H, Ma PX, Langer R, Vacanti JP. The effect of donor and recipient age on engraftment of tissue-engineered liver. J Ped Surg 1997;32(2): 357-360.
32. Kim TH, Lee HM, Utsonomiya H, Ma P, Langer R, Schmidt EV, Vacanti JP. Enhanced survival of transgenic hepatocytes expressing hepatocyte growth factor in hepatocyte tissue engineering. Transplant Proc 1997;29(1-2):858-860.
33. Laurencin CT, Attawia MA, Elgendy HE, Herbert KM. Tissue-engineered bone regeneration using degradable polymers: The formation of mineralized matrices. Bone 1996;19(1):93S-99S.
34. Attawia MA, Herbert KM, Laurencin CT. Osteoblast-like cell adherence and migration through 3-dimensional porous polymer matrices. Biochem Biophys Res Comm 1995;213(2):639-644.