Performance standards and alternative assays: Practical insights from skin sensitization

Regulatory Toxicology and Pharmacology

Volumn 65, Issue 2, 2013, Pages 278-285

  Kolle, Susanne N ^a   Basketter, David A ^b   Casati, Silvia ^c   Stokes, William S ^d   Strickland, Judy ^e   van Ravenzwaay, Bennard ^a   Vohr, Hans Werner ^f   Landsiedel, Robert ^a  

^a BASF SE   (Germany)

^b DABMEB CONSULTANCY LTD   (United Kingdom)

^c JOINT RESEARCH CENTRE   (Italy)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^e INTEGRATED LABORATORY SYSTEMS   (United States)

^f BAYER PHARMA AG   (Germany)

Author keywords

Alternatives; Local lymph node assay; Lymph node cell counts; Performance standards; Skin sensitization; Validation

Indexed keywords

CHLOROBENZENE; METHACRYLIC ACID METHYL ESTER; NICKEL CHLORIDE; SALICYLIC ACID; SALICYLIC ACID METHYL ESTER;

ACCURACY; ARTICLE; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; INTERMETHOD COMPARISON; LOCAL LYMPH NODE ASSAY; LYMPH NODE CELL COUNT; MEDICAL PROCEDURES; PERFORMANCE MEASUREMENT SYSTEM; PREDICTION; PRIORITY JOURNAL; PROCESS DEVELOPMENT; RELIABILITY; SKIN SENSITIZATION; STANDARDIZATION; TOXICITY TESTING; VALIDATION PROCESS;

ALLERGENS; ANIMAL TESTING ALTERNATIVES; ANIMALS; DERMATITIS, CONTACT; HUMANS; HYPERSENSITIVITY; LOCAL LYMPH NODE ASSAY; REPRODUCIBILITY OF RESULTS; SKIN IRRITANCY TESTS; TOXICITY TESTS;

EID: 84873264075     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2012.12.006     Document Type: Article

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