Mitochondrial electron transport is inhibited by disappearance of metallothionein in human bronchial epithelial cells following exposure to silver nitrate

Toxicology

Volumn 305, Issue , 2013, Pages 20-29

  Miyayama, Takamitsu ^a   Arai, Yuta ^b   Suzuki, Noriyuki ^b   Hirano, Seishiro ^a,b  

^a NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

^b CHIBA UNIVERSITY   (Japan)

Author keywords

ICP MS; Metallothionein; Mitochondria; ROS; Silver

Indexed keywords

CYTOCHROME C OXIDASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; HYDROGEN PEROXIDE; MESSENGER RNA; METALLOTHIONEIN I; METALLOTHIONEIN II; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SILVER NITRATE; SUCCINATE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRONCHUS MUCOSA; CELL DAMAGE; CELL FRACTIONATION; CELL VIABILITY; CELLULAR DISTRIBUTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CULTURE MEDIUM; CYTOSOL; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME INHIBITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRIAL RESPIRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; RAT;

ANTI-INFECTIVE AGENTS, LOCAL; BRONCHI; CELL LINE; CELL SURVIVAL; COPPER; CYTOCHROMES C; CYTOSOL; ELECTRON TRANSPORT; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; EPITHELIAL CELLS; GLUTATHIONE; HUMANS; HYDROGEN PEROXIDE; METALLOTHIONEIN; MITOCHONDRIA; OXYGEN CONSUMPTION; REAL-TIME POLYMERASE CHAIN REACTION; SILVER; SILVER NITRATE; ZINC;

EID: 84873251043     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2013.01.004     Document Type: Article

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