Synergistic protective effect of cyclosporin A and rotenone against hypoxia-reoxygenation in cardiomyocytes

Journal of Molecular and Cellular Cardiology

Volumn 56, Issue 1, 2013, Pages 55-62

  Teixeira, Geoffrey ^a,b   Abrial, Maryline ^a,b   Portier, Karine ^a,b,c   Chiari, Pascal ^a,b,d   Couture Lepetit, Elisabeth ^a,b   Tourneur, Yves ^a,b   Ovize, Michel ^a,b,d   Gharib, Abdallah ^a,b  

^a CarMeN   (France)

^b UNIVERSITÉ LYON 1   (France)

^c UNIVERSITÉ DE LYON   (France)

^d LOUIS PRADEL HOSPITAL   (France)

Author keywords

Adult mice cardiomyocytes; Complex I; Cyclophilin D; Cytoprotection; Hypoxia reoxygenation; Mitochondrial permeability transition pore

Indexed keywords

CALCIUM; COBALT CHLORIDE; CYCLOSPORIN A; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; PROPIDIUM IODIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE;

ADULT ANIMAL; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL DEATH; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME INHIBITION; GENE INACTIVATION; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; ISCHEMIC POSTCONDITIONING; ISCHEMIC PRECONDITIONING; MALE; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; REOXYGENATION; STAINING; WILD TYPE;

ANIMALS; CARDIOTONIC AGENTS; CELL DEATH; CELL HYPOXIA; CELLS, CULTURED; CYCLOPHILINS; CYCLOSPORINE; DRUG SYNERGISM; ELECTRON TRANSPORT COMPLEX I; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA, HEART; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; OXYGEN CONSUMPTION; PERMEABILITY; ROTENONE;

MUS;

EID: 84873197052     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2012.11.023     Document Type: Article

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