메뉴 건너뛰기




Volumn 9, Issue 3, 2013, Pages 5821-5829

Microstructured titanium regulates interleukin production by osteoblasts, an effect modulated by exogenous BMP-2

Author keywords

Bone morphogenetic protein; Inflammation; Microstructure; Osteoblast; Titanium

Indexed keywords

BONE; CELL SIGNALING; MICROSTRUCTURE; OSTEOBLASTS; RECOMBINANT PROTEINS; SIGNALING; TISSUE CULTURE;

EID: 84873163682     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2012.10.030     Document Type: Article
Times cited : (36)

References (68)
  • 3
    • 42749083246 scopus 로고    scopus 로고
    • Functions of RANKL/RANK/OPG in bone modeling and remodeling
    • B.F. Boyce, and L. Xing Functions of RANKL/RANK/OPG in bone modeling and remodeling Arch Biochem Biophys 473 2008 139 146
    • (2008) Arch Biochem Biophys , vol.473 , pp. 139-146
    • Boyce, B.F.1    Xing, L.2
  • 4
    • 67349122805 scopus 로고    scopus 로고
    • Mechanisms regulating increased production of osteoprotegerin by osteoblasts cultured on microstructured titanium surfaces
    • Z. Schwartz, R. Olivares-Navarrete, M. Wieland, D.L. Cochran, and B.D. Boyan Mechanisms regulating increased production of osteoprotegerin by osteoblasts cultured on microstructured titanium surfaces Biomaterials 30 2009 3390 3396
    • (2009) Biomaterials , vol.30 , pp. 3390-3396
    • Schwartz, Z.1    Olivares-Navarrete, R.2    Wieland, M.3    Cochran, D.L.4    Boyan, B.D.5
  • 5
    • 45249115763 scopus 로고    scopus 로고
    • Modulation of the inflammatory response for enhanced bone tissue regeneration
    • DOI 10.1089/ten.teb.2008.0038
    • P.M. Mountziaris, and A.G. Mikos Modulation of the inflammatory response for enhanced bone tissue regeneration Tissue Eng B Rev 14 2008 179 186 (Pubitemid 351839215)
    • (2008) Tissue Engineering - Part B: Reviews , vol.14 , Issue.2 , pp. 179-186
    • Mountziaris, P.M.1    Mikos, A.G.2
  • 7
    • 0034999587 scopus 로고    scopus 로고
    • Expression of osteoprotegerin, receptor activator of NF-κB ligand (osteoprotegerin ligand) and related proinflammatory cytokines during fracture healing
    • T. Kon, T.J. Cho, T. Aizawa, M. Yamazaki, N. Nooh, and D. Graves Expression of osteoprotegerin, receptor activator of NF-kappaB ligand (osteoprotegerin ligand) and related proinflammatory cytokines during fracture healing J Bone Miner Res 16 2001 1004 1014 (Pubitemid 32467144)
    • (2001) Journal of Bone and Mineral Research , vol.16 , Issue.6 , pp. 1004-1014
    • Kon, T.1    Cho, T.-J.2    Aizawa, T.3    Yamazaki, M.4    Nooh, N.5    Graves, D.6    Gerstenfeld, L.C.7    Einhorn, T.A.8
  • 8
    • 0036181393 scopus 로고    scopus 로고
    • Differential temporal expression of members of the transforming growth factor β superfamily during murine fracture healing
    • T.J. Cho, L.C. Gerstenfeld, and T.A. Einhorn Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing J Bone Miner Res 17 2002 513 520 (Pubitemid 34171766)
    • (2002) Journal of Bone and Mineral Research , vol.17 , Issue.3 , pp. 513-520
    • Cho, T.-J.1    Gerstenfeld, L.C.2    Einhorn, T.A.3
  • 9
    • 33644990212 scopus 로고    scopus 로고
    • Microarray analysis of gene expression during the inflammation and endochondral bone formation stages of rat femur fracture repair
    • C.H. Rundle, H. Wang, H. Yu, R.B. Chadwick, E.I. Davis, and J.E. Wergedal Microarray analysis of gene expression during the inflammation and endochondral bone formation stages of rat femur fracture repair Bone 38 2006 521 529
    • (2006) Bone , vol.38 , pp. 521-529
    • Rundle, C.H.1    Wang, H.2    Yu, H.3    Chadwick, R.B.4    Davis, E.I.5    Wergedal, J.E.6
  • 12
    • 64049106584 scopus 로고    scopus 로고
    • Diagnosis and treatment of osteoporosis in chronic renal disease
    • P.D. Miller Diagnosis and treatment of osteoporosis in chronic renal disease Semin Nephrol 29 2009 144 155
    • (2009) Semin Nephrol , vol.29 , pp. 144-155
    • Miller, P.D.1
  • 13
    • 36348985084 scopus 로고    scopus 로고
    • Bone disorders in chronic liver disease
    • DOI 10.1002/hep.21852
    • J. Collier Bone disorders in chronic liver disease Hepatology 46 2007 1271 1278 (Pubitemid 350144791)
    • (2007) Hepatology , vol.46 , Issue.4 , pp. 1271-1278
    • Collier, J.1
  • 14
    • 79952500914 scopus 로고    scopus 로고
    • In vivo gene expression profile of guided bone regeneration associated with a microrough titanium surface
    • N. Donos, M. Retzepi, I. Wall, S. Hamlet, and S. Ivanovski In vivo gene expression profile of guided bone regeneration associated with a microrough titanium surface Clin Oral Implants Res 22 2011 390 398
    • (2011) Clin Oral Implants Res , vol.22 , pp. 390-398
    • Donos, N.1    Retzepi, M.2    Wall, I.3    Hamlet, S.4    Ivanovski, S.5
  • 17
    • 79251612605 scopus 로고    scopus 로고
    • Dendritic cell responses to surface properties of clinical titanium surfaces
    • P.M. Kou, Z. Schwartz, B.D. Boyan, and J.E. Babensee Dendritic cell responses to surface properties of clinical titanium surfaces Acta Biomater 7 2011 1354 1363
    • (2011) Acta Biomater , vol.7 , pp. 1354-1363
    • Kou, P.M.1    Schwartz, Z.2    Boyan, B.D.3    Babensee, J.E.4
  • 18
    • 0024360388 scopus 로고
    • The biology of interleukin-6
    • T. Kishimoto The biology of interleukin-6 Blood 74 1989 1 10 (Pubitemid 19187402)
    • (1989) Blood , vol.74 , Issue.1 , pp. 1-10
    • Kishimoto, T.1
  • 19
    • 33744768634 scopus 로고    scopus 로고
    • Regulation of osteoclast differentiation
    • DOI 10.1196/annals.1346.013
    • G.D. Roodman Regulation of osteoclast differentiation Ann N Y Acad Sci 1068 2006 100 109 (Pubitemid 43824141)
    • (2006) Annals of the New York Academy of Sciences , vol.1068 , Issue.1 , pp. 100-109
    • Roodman, G.D.1
  • 20
    • 14244256520 scopus 로고    scopus 로고
    • Cytokines link osteoblasts and inflammation: Microarray analysis of interleukin-17- and TNF-α-induced genes in bone cells
    • DOI 10.1189/jlb.0904490
    • F. Shen, M.J. Ruddy, P. Plamondon, and S.L. Gaffen Cytokines link osteoblasts and inflammation: microarray analysis of interleukin-17- and TNF-alpha-induced genes in bone cells J Leukoc Biol 77 2005 388 399 (Pubitemid 40289569)
    • (2005) Journal of Leukocyte Biology , vol.77 , Issue.3 , pp. 388-399
    • Shen, F.1    Ruddy, M.J.2    Plamondon, P.3    Gaffen, S.L.4
  • 22
    • 0034090602 scopus 로고    scopus 로고
    • Anti-inflammatory cytokines
    • S.M. Opal, and V.A. DePalo Anti-inflammatory cytokines Chest 117 2000 1162 1172 (Pubitemid 30228378)
    • (2000) Chest , vol.117 , Issue.4 , pp. 1162-1172
    • Opal, S.M.1    DePalo, V.A.2
  • 23
    • 0036962733 scopus 로고    scopus 로고
    • Gene expression of bone-associated cytokines in MG63 osteoblast-like cells incubated with acrylic bone cement extracts in minimum essential medium
    • DOI 10.1163/15685620260449697
    • E. Cenni, D. Granchi, G. Ciapetti, L. Savarino, A. Corradini, and M. Vancini Gene expression of bone-associated cytokines in MG63 osteoblast-like cells incubated with acrylic bone cement extracts in minimum essential medium J Biomater Sci Polym Ed 13 2002 1283 1294 (Pubitemid 36124100)
    • (2002) Journal of Biomaterials Science, Polymer Edition , vol.13 , Issue.12 , pp. 1283-1294
    • Cenni, E.1    Granchi, D.2    Ciapetti, G.3    Savarino, L.4    Corradini, A.5    Vancini, M.6    Giunti, A.7
  • 26
    • 13444291335 scopus 로고    scopus 로고
    • BMP signaling in skeletal development
    • DOI 10.1016/j.bbrc.2004.11.067, Vertebrate Skeletal Biology
    • M. Wan, and X. Cao BMP signaling in skeletal development Biochem Biophys Res Commun 328 2005 651 657 (Pubitemid 40208302)
    • (2005) Biochemical and Biophysical Research Communications , vol.328 , Issue.3 , pp. 651-657
    • Wan, M.1    Cao, X.2
  • 27
    • 78650183297 scopus 로고    scopus 로고
    • Osseointegration by bone morphogenetic protein-2 and transforming growth factor beta2 coated titanium implants in femora of New Zealand white rabbits
    • F. Thorey, H. Menzel, C. Lorenz, G. Gross, A. Hoffmann, and H. Windhagen Osseointegration by bone morphogenetic protein-2 and transforming growth factor beta2 coated titanium implants in femora of New Zealand white rabbits Indian J Orthop 45 2011 57 62
    • (2011) Indian J Orthop , vol.45 , pp. 57-62
    • Thorey, F.1    Menzel, H.2    Lorenz, C.3    Gross, G.4    Hoffmann, A.5    Windhagen, H.6
  • 28
    • 78650093313 scopus 로고    scopus 로고
    • Evaluation of implants coated with recombinant human bone morphogenetic protein-2 and vacuum-dried using the critical-size supraalveolar peri-implant defect model in dogs
    • J.F. Decker, J. Lee, C.A. Cortella, G. Polimeni, M.D. Rohrer, and J.M. Wozney Evaluation of implants coated with recombinant human bone morphogenetic protein-2 and vacuum-dried using the critical-size supraalveolar peri-implant defect model in dogs J Periodontol 81 2010 1839 1849
    • (2010) J Periodontol , vol.81 , pp. 1839-1849
    • Decker, J.F.1    Lee, J.2    Cortella, C.A.3    Polimeni, G.4    Rohrer, M.D.5    Wozney, J.M.6
  • 29
    • 36349024668 scopus 로고    scopus 로고
    • Current and future clinical applications of bone morphogenetic proteins in orthopaedic trauma surgery
    • DOI 10.1007/s00264-007-0424-8
    • G.B. Bishop, and T.A. Einhorn Current and future clinical applications of bone morphogenetic proteins in orthopaedic trauma surgery Int Orthop 31 2007 721 727 (Pubitemid 350160314)
    • (2007) International Orthopaedics , vol.31 , Issue.6 , pp. 721-727
    • Bishop, G.B.1    Einhorn, T.A.2
  • 30
    • 85045483986 scopus 로고    scopus 로고
    • Clinical effectiveness and cost-effectiveness of bone morphogenetic proteins in the non-healing of fractures and spinal fusion: A systematic review
    • K.R. Garrison, S. Donell, J. Ryder, I. Shemilt, M. Mugford, and I. Harvey Clinical effectiveness and cost-effectiveness of bone morphogenetic proteins in the non-healing of fractures and spinal fusion: a systematic review Health Technol Assess 11 iii-iv 2007 1 150
    • (2007) Health Technol Assess , vol.11 , Issue.3-4 , pp. 1-150
    • Garrison, K.R.1    Donell, S.2    Ryder, J.3    Shemilt, I.4    Mugford, M.5    Harvey, I.6
  • 31
    • 0037442894 scopus 로고    scopus 로고
    • Radiographic assessment of interbody fusion using recombinant human bone morphogenetic protein type 2
    • DOI 10.1097/00007632-200302150-00012
    • J.K. Burkus, J.D. Dorchak, and D.L. Sanders Radiographic assessment of interbody fusion using recombinant human bone morphogenetic protein type 2 Spine (Phila Pa 1976) 28 2003 372 377 (Pubitemid 36232619)
    • (2003) Spine , vol.28 , Issue.4 , pp. 372-377
    • Burkus, J.K.1    Dorchak, J.D.2    Sanders, D.L.3
  • 32
    • 23244467021 scopus 로고    scopus 로고
    • Initial fusion rates with recombinant human bone morphogenetic protein-2/compression resistant matrix and a hydroxyapatite and tricalcium phosphate/collagen carrier in posterolateral spinal fusion
    • DOI 10.1097/01.brs.0000172157.39513.80
    • S.D. Glassman, J.R. Dimar, L.Y. Carreon, M.J. Campbell, R.M. Puno, and J.R. Johnson Initial fusion rates with recombinant human bone morphogenetic protein-2/compression resistant matrix and a hydroxyapatite and tricalcium phosphate/collagen carrier in posterolateral spinal fusion Spine (Phila Pa 1976) 30 2005 1694 1698 (Pubitemid 41099480)
    • (2005) Spine , vol.30 , Issue.15 , pp. 1694-1698
    • Glassman, S.D.1    Dimar, J.R.2    Carreon, L.Y.3    Campbell, M.J.4    Puno, R.M.5    Johnson, J.R.6
  • 33
    • 0036894554 scopus 로고    scopus 로고
    • Use of recombinant human bone morphogenetic protein-2 to achieve posterolateral lumbar spine fusion in humans: A prospective, randomized clinical pilot trial 2002 volvo award in clinical studies
    • DOI 10.1097/00007632-200212010-00005
    • S.D. Boden, J. Kang, H. Sandhu, and J.G. Heller Use of recombinant human bone morphogenetic protein-2 to achieve posterolateral lumbar spine fusion in humans: a prospective, randomized clinical pilot trial: 2002 Volvo Award in clinical studies Spine (Phila Pa 1976) 27 2002 2662 2673 (Pubitemid 35425320)
    • (2002) Spine , vol.27 , Issue.23 , pp. 2662-2673
    • Boden, S.D.1    Kang, J.2    Sandhu, H.3    Heller, J.G.4
  • 34
    • 51749087337 scopus 로고    scopus 로고
    • Alveolar ridge augmentation using implants coated with recombinant human bone morphogenetic protein-2: Radiographic observations
    • K.N. Leknes, J. Yang, M. Qahash, G. Polimeni, C. Susin, and U.M. Wikesjo Alveolar ridge augmentation using implants coated with recombinant human bone morphogenetic protein-2: radiographic observations Clin Oral Implants Res 19 2008 1027 1033
    • (2008) Clin Oral Implants Res , vol.19 , pp. 1027-1033
    • Leknes, K.N.1    Yang, J.2    Qahash, M.3    Polimeni, G.4    Susin, C.5    Wikesjo, U.M.6
  • 35
    • 77649131474 scopus 로고    scopus 로고
    • Complications associated with the use of bone morphogenetic protein in pediatric patients
    • M.E. Oetgen, and B.S. Richards Complications associated with the use of bone morphogenetic protein in pediatric patients J Pediatr Orthop 30 2010 192 198
    • (2010) J Pediatr Orthop , vol.30 , pp. 192-198
    • Oetgen, M.E.1    Richards, B.S.2
  • 36
    • 67649117871 scopus 로고    scopus 로고
    • Adverse effects of posterior lumbar interbody fusion using rhBMP-2
    • [author reply 4]
    • T. Smoljanovic, I. Bojanic, and D. Delimar Adverse effects of posterior lumbar interbody fusion using rhBMP-2 Eur Spine J 18 2009 920 923 [author reply 4]
    • (2009) Eur Spine J , vol.18 , pp. 920-923
    • Smoljanovic, T.1    Bojanic, I.2    Delimar, D.3
  • 37
    • 79959959003 scopus 로고    scopus 로고
    • Bone morphogenetic protein-binding peptide reduces the inflammatory response to recombinant human bone morphogenetic protein-2 and recombinant human bone morphogenetic protein-7 in a rodent model of soft-tissue inflammation
    • K.B. Lee, S.S. Murray, C.E. Taghavi, K.J. Song, E.J. Brochmann, and J.S. Johnson Bone morphogenetic protein-binding peptide reduces the inflammatory response to recombinant human bone morphogenetic protein-2 and recombinant human bone morphogenetic protein-7 in a rodent model of soft-tissue inflammation Spine J 11 2011 568 576
    • (2011) Spine J , vol.11 , pp. 568-576
    • Lee, K.B.1    Murray, S.S.2    Taghavi, C.E.3    Song, K.J.4    Brochmann, E.J.5    Johnson, J.S.6
  • 39
    • 33947591669 scopus 로고    scopus 로고
    • Requirement for both micron- and submicron scale structure for synergistic responses of osteoblasts to substrate surface energy and topography
    • DOI 10.1016/j.biomaterials.2007.02.024, PII S0142961207001779
    • G. Zhao, A.L. Raines, M. Wieland, Z. Schwartz, and B.D. Boyan Requirement for both micron- and submicron scale structure for synergistic responses of osteoblasts to substrate surface energy and topography Biomaterials 28 2007 2821 2829 (Pubitemid 46482664)
    • (2007) Biomaterials , vol.28 , Issue.18 , pp. 2821-2829
    • Zhao, G.1    Raines, A.L.2    Wieland, M.3    Schwartz, Z.4    Boyan, B.D.5
  • 41
    • 12244298235 scopus 로고    scopus 로고
    • A systematic review of the influence of different titanium surfaces on proliferation, differentiation and protein synthesis of osteoblast-like MG63 cells
    • DOI 10.1111/j.1600-0501.2004.01054.x
    • M. Bachle, and R.J. Kohal A systematic review of the influence of different titanium surfaces on proliferation, differentiation and protein synthesis of osteoblast-like MG63 cells Clin Oral Implants Res 15 2004 683 692 (Pubitemid 40115756)
    • (2004) Clinical Oral Implants Research , vol.15 , Issue.6 , pp. 683-692
    • Bachle, M.1    Kohal, R.J.2
  • 42
    • 0029256715 scopus 로고
    • Effect of titanium surface roughness on proliferation, differentiation, and protein synthesis of human osteoblast-like cells (MG63)
    • J.Y. Martin, Z. Schwartz, T.W. Hummert, D.M. Schraub, J. Simpson, and J. Lankford Jr. Effect of titanium surface roughness on proliferation, differentiation, and protein synthesis of human osteoblast-like cells (MG63) J Biomed Mater Res 29 1995 389 401
    • (1995) J Biomed Mater Res , vol.29 , pp. 389-401
    • Martin, J.Y.1    Schwartz, Z.2    Hummert, T.W.3    Schraub, D.M.4    Simpson, J.5    Lankford Jr., J.6
  • 43
    • 33846243774 scopus 로고    scopus 로고
    • Blockade of transforming growth factor-β-activated kinase 1 activity enhances TRAIL-induced apoptosis through activation of a caspase cascade
    • DOI 10.1158/1535-7163.MCT-06-0379
    • M.K. Choo, N. Kawasaki, P. Singhirunnusorn, K. Koizumi, S. Sato, and S. Akira Blockade of transforming growth factor-beta-activated kinase 1 activity enhances TRAIL-induced apoptosis through activation of a caspase cascade Mol Cancer Ther 5 2006 2970 2976 (Pubitemid 46092038)
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.12 , pp. 2970-2976
    • Choo, M.-K.1    Kawasaki, N.2    Singhirunnusorn, P.3    Koizumi, K.4    Sato, S.5    Akira, S.6    Saiki, I.7    Sakurai, H.8
  • 46
    • 51449091152 scopus 로고    scopus 로고
    • Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells
    • J. Hao, M.A. Daleo, C.K. Murphy, P.B. Yu, J.N. Ho, and J. Hu Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells PLoS One 3 2008 e2904
    • (2008) PLoS One , vol.3 , pp. 2904
    • Hao, J.1    Daleo, M.A.2    Murphy, C.K.3    Yu, P.B.4    Ho, J.N.5    Hu, J.6
  • 47
    • 0021751197 scopus 로고
    • Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C
    • DOI 10.1021/bi00316a032
    • H. Hidaka, M. Inagaki, S. Kawamoto, and Y. Sasaki Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C Biochemistry 23 1984 5036 5041 (Pubitemid 15206436)
    • (1984) Biochemistry , vol.23 , Issue.21 , pp. 5036-5041
    • Hidaka, H.1    Inagaki, M.2    Kawamoto, S.3    Sasaki, Y.4
  • 48
    • 0033618495 scopus 로고    scopus 로고
    • Effects of PKA inhibitors, H-compounds, on epithelial Na+ channels via PKA-independent mechanisms
    • N. Niisato, Y. Ito, and Y. Marunaka Effects of PKA inhibitors, H-compounds, on epithelial Na+ channels via PKA-independent mechanisms Life Sci 65 1999 PL109 PL114
    • (1999) Life Sci , vol.65
    • Niisato, N.1    Ito, Y.2    Marunaka, Y.3
  • 49
    • 62949128877 scopus 로고    scopus 로고
    • TNF-alpha and IL-1beta inhibit RUNX2 and collagen expression but increase alkaline phosphatase activity and mineralization in human mesenchymal stem cells
    • J. Ding, O. Ghali, P. Lencel, O. Broux, C. Chauveau, and J.C. Devedjian TNF-alpha and IL-1beta inhibit RUNX2 and collagen expression but increase alkaline phosphatase activity and mineralization in human mesenchymal stem cells Life Sci 84 2009 499 504
    • (2009) Life Sci , vol.84 , pp. 499-504
    • Ding, J.1    Ghali, O.2    Lencel, P.3    Broux, O.4    Chauveau, C.5    Devedjian, J.C.6
  • 53
    • 0034051068 scopus 로고    scopus 로고
    • Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty
    • DOI 10.1146/annurev.med.51.1.245
    • W.B. Ershler, and E.T. Keller Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty Annu Rev Med 51 2000 245 270 (Pubitemid 30216036)
    • (2000) Annual Review of Medicine , vol.51 , pp. 245-270
    • Ershler, W.B.1    Keller, E.T.2
  • 56
    • 77952238280 scopus 로고    scopus 로고
    • Proinflammatory cytokines (IL-1beta and TNF-alpha) and chemokines (IL-8 and MIP-1alpha) as markers of peri-implant tissue condition
    • A.B. Petkovic, S.M. Matic, N.V. Stamatovic, D.V. Vojvodic, T.M. Todorovic, and Z.R. Lazic Proinflammatory cytokines (IL-1beta and TNF-alpha) and chemokines (IL-8 and MIP-1alpha) as markers of peri-implant tissue condition Int J Oral Maxillofac Surg 39 2010 478 485
    • (2010) Int J Oral Maxillofac Surg , vol.39 , pp. 478-485
    • Petkovic, A.B.1    Matic, S.M.2    Stamatovic, N.V.3    Vojvodic, D.V.4    Todorovic, T.M.5    Lazic, Z.R.6
  • 57
    • 76849112495 scopus 로고    scopus 로고
    • Runx2 association with progression of prostate cancer in patients: Mechanisms mediating bone osteolysis and osteoblastic metastatic lesions
    • J. Akech, J.J. Wixted, K. Bedard, M. van der Deen, S. Hussain, and T.A. Guise Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions Oncogene 29 2010 811 821
    • (2010) Oncogene , vol.29 , pp. 811-821
    • Akech, J.1    Wixted, J.J.2    Bedard, K.3    Van Der Deen, M.4    Hussain, S.5    Guise, T.A.6
  • 59
    • 0034618580 scopus 로고    scopus 로고
    • Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-kappaB ligand: Modulation of the expression by osteotropic factors and cytokines
    • T. Nakashima, Y. Kobayashi, S. Yamasaki, A. Kawakami, K. Eguchi, and H. Sasaki Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-kappaB ligand: modulation of the expression by osteotropic factors and cytokines Biochem Biophys Res Commun 275 2000 768 775
    • (2000) Biochem Biophys Res Commun , vol.275 , pp. 768-775
    • Nakashima, T.1    Kobayashi, Y.2    Yamasaki, S.3    Kawakami, A.4    Eguchi, K.5    Sasaki, H.6
  • 60
    • 0030036614 scopus 로고    scopus 로고
    • Net inflammatory capacity of human septic shock plasma evaluated by a monocyte-based target cell assay: Identification of interleukin-10 as a major functional deactivator of human monocytes
    • DOI 10.1084/jem.184.1.51
    • P. Brandtzaeg, L. Osnes, R. Ovstebo, G.B. Joo, A.B. Westvik, and P. Kierulf Net inflammatory capacity of human septic shock plasma evaluated by a monocyte-based target cell assay: identification of interleukin-10 as a major functional deactivator of human monocytes J Exp Med 184 1996 51 60 (Pubitemid 26247214)
    • (1996) Journal of Experimental Medicine , vol.184 , Issue.1 , pp. 51-60
    • Brandtzaeg, P.1    Osnes, L.2    Ovstebo, R.3    Joo, G.B.4    Westvik, A.-B.5    Kierulf, P.6
  • 61
    • 0031944393 scopus 로고    scopus 로고
    • IL-10-mediated suppression of TNF-α production is independent of its ability to inhibit NFκB activity
    • DOI 10.1002/(SICI)1521-4141(199805)28:05<1719::AID-IMMU1719>3.0. CO;2-Q
    • C.J. Clarke, A. Hales, A. Hunt, and B.M. Foxwell IL-10-mediated suppression of TNF-alpha production is independent of its ability to inhibit NF kappa B activity Eur J Immunol 28 1998 1719 1726 (Pubitemid 28221177)
    • (1998) European Journal of Immunology , vol.28 , Issue.5 , pp. 1719-1726
    • Clarke, C.J.P.1    Hales, A.2    Hunt, A.3    Foxwell, B.M.J.4
  • 62
    • 84859715902 scopus 로고    scopus 로고
    • The effect of hydrophilic titanium surface modification on macrophage inflammatory cytokine gene expression
    • S. Hamlet, M. Alfarsi, R. George, and S. Ivanovski The effect of hydrophilic titanium surface modification on macrophage inflammatory cytokine gene expression Clin Oral Implants Res 23 2011 584 590
    • (2011) Clin Oral Implants Res , vol.23 , pp. 584-590
    • Hamlet, S.1    Alfarsi, M.2    George, R.3    Ivanovski, S.4
  • 63
    • 84860215314 scopus 로고    scopus 로고
    • Recombinant bone morphogenetic protein-2 induces up-regulation of vascular endothelial growth factor and interleukin 6 in human pre-osteoblasts: Role of reactive oxygen species
    • S. Akeel, A. El-Awady, K. Hussein, M. El-Refaey, M. Elsalanty, and M. Sharawy Recombinant bone morphogenetic protein-2 induces up-regulation of vascular endothelial growth factor and interleukin 6 in human pre-osteoblasts: role of reactive oxygen species Arch Oral Biol 57 2011 445 452
    • (2011) Arch Oral Biol , vol.57 , pp. 445-452
    • Akeel, S.1    El-Awady, A.2    Hussein, K.3    El-Refaey, M.4    Elsalanty, M.5    Sharawy, M.6
  • 64
    • 84865012015 scopus 로고    scopus 로고
    • BMP2 induces osteoblast apoptosis in a maturation state and noggin-dependent manner
    • S.L. Hyzy, R. Olivares-Navarrete, Z. Schwartz, and B.D. Boyan BMP2 induces osteoblast apoptosis in a maturation state and noggin-dependent manner J Cell Biochem 113 2012 3236 3245
    • (2012) J Cell Biochem , vol.113 , pp. 3236-3245
    • Hyzy, S.L.1    Olivares-Navarrete, R.2    Schwartz, Z.3    Boyan, B.D.4
  • 65
  • 66
    • 78149342873 scopus 로고    scopus 로고
    • In vivo RNAi-mediated silencing of TAK1 decreases inflammatory Th1 and Th17 cells through targeting of myeloid cells
    • G. Courties, V. Seiffart, J. Presumey, V. Escriou, D. Scherman, and J. Zwerina In vivo RNAi-mediated silencing of TAK1 decreases inflammatory Th1 and Th17 cells through targeting of myeloid cells Blood 116 2010 3505 3516
    • (2010) Blood , vol.116 , pp. 3505-3516
    • Courties, G.1    Seiffart, V.2    Presumey, J.3    Escriou, V.4    Scherman, D.5    Zwerina, J.6
  • 67
    • 0033609409 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 enhances osteoclast formation mediated by interleukin-1α through upregulation of osteoclast differentiation factor and cyclooxygenase-2
    • DOI 10.1006/bbrc.1999.0715
    • M. Koide, Y. Murase, K. Yamato, T. Noguchi, N. Okahashi, and T. Nishihara Bone morphogenetic protein-2 enhances osteoclast formation mediated by interleukin-1alpha through upregulation of osteoclast differentiation factor and cyclooxygenase-2 Biochem Biophys Res Commun 259 1999 97 102 (Pubitemid 29264000)
    • (1999) Biochemical and Biophysical Research Communications , vol.259 , Issue.1 , pp. 97-102
    • Koide, M.1    Murase, Y.2    Yamato, K.3    Noguchi, T.4    Okahashi, N.5    Nishihara, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.