Cellular and molecular mechanisms of accelerated fracture healing by COX2 gene therapy. Studies in a mouse model of multiple fractures.

Bone

Volumn 53, Issue 2, 2013, Pages 369-381

  Lau, K H William ^a,b   Kothari, Vishal ^a   Das, Amitava ^a   Zhang, Xiao Bing ^a   Baylink, David J ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Angiogenesis; Cartilage remodeling; COX2; Fracture healing; Gene therapy; Mesenchymal stem cells

Indexed keywords

ALKALINE PHOSPHATASE BONE ISOENZYME; ALPHA SMOOTH MUSCLE ACTIN; ALPHA6 INTEGRIN; CD31 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; CYCLOOXYGENASE 2; ENDOSTATIN; GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; MEMBRANE PROTEIN; MESSENGER RNA; NESTIN; OSTEOCALCIN; OSTEOPONTIN; PODOCALYXIN LIKE PROTEIN; STROMAL CELL DERIVED FACTOR 1; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; BONE DEVELOPMENT; BONE REMODELING; CALLUS; CARTILAGE CELL; CELL DIFFERENTIATION; CELL EXPANSION; CELL TRANSPORT; CHONDROGENESIS; CONTROLLED STUDY; COX2 GENE; CYTOLOGY; DISEASE MODEL; FRACTURE HEALING; GENE THERAPY; IMMUNOHISTOCHEMISTRY; MALE; MESENCHYMAL STEM CELL; MOLECULAR MECHANICS; MOUSE; NONHUMAN; OSTEOCLAST; PROTEIN EXPRESSION; TIBIA FRACTURE; TREATMENT OUTCOME; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; CYCLOOXYGENASE 2; FRACTURE HEALING; FRACTURES, BONE; GENETIC THERAPY; MALE; MICE; MICE, INBRED C57BL; TIBIAL FRACTURES;

EID: 84873130447     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2013.01.003     Document Type: Article

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