메뉴 건너뛰기




Volumn 59, Issue 4, 2012, Pages

The effect of selective serotonin reuptake inhibitors in healthy first-degree relatives of patients with major depressive disorder: - An experimental medicine blinded controlled trial

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; DEXAMETHASONE; ESCITALOPRAM; GLUCOCORTICOID; HYDROCORTISONE; PLACEBO; CITALOPRAM; SEROTONIN UPTAKE INHIBITOR;

EID: 84873128554     PISSN: None     EISSN: 22451919     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (5)

References (117)
  • 1
    • 0026548961 scopus 로고
    • A popula-tion-based twin study of major depression in women. The impact of varying definitions of illness
    • Kendler KS, Neale MC, Kessler RC, Heath AC, Eaves LJ. A popula-tion-based twin study of major depression in women. The impact of varying definitions of illness. Arch Gen Psychiatry 1992;49:257-266.
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 257-266
    • Kendler, K.S.1    Neale, M.C.2    Kessler, R.C.3    Heath, A.C.4    Eaves, L.J.5
  • 2
    • 0028156958 scopus 로고
    • Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey
    • Kessler RC, McGonagle KA, Zhao S et al. Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey. Arch Gen Psychiatry 1994;51:8-19.
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 8-19
    • Kessler, R.C.1    McGonagle, K.A.2    Zhao, S.3
  • 3
    • 0442291947 scopus 로고    scopus 로고
    • Prevalence of major depres-sion and stress indicators in the Danish general population
    • Olsen LR, Mortensen EL, Bech P. Prevalence of major depres-sion and stress indicators in the Danish general population. Acta Psychiatr Scand 2004;109:96-103.
    • (2004) Acta Psychiatr Scand , vol.109 , pp. 96-103
    • Olsen, L.R.1    Mortensen, E.L.2    Bech, P.3
  • 5
    • 8344238181 scopus 로고    scopus 로고
    • Course of illness in de-pressive and bipolar disorders. Naturalistic study, 1994-1999
    • Kessing LV, Hansen MG, Andersen PK. Course of illness in de-pressive and bipolar disorders. Naturalistic study, 1994-1999. Br J Psychiatry 2004;185:372-377.
    • (2004) Br J Psychiatry , vol.185 , pp. 372-377
    • Kessing, L.V.1    Hansen, M.G.2    Andersen, P.K.3
  • 7
    • 0031889557 scopus 로고    scopus 로고
    • Recurrence in affective disorder. II. Effect of age and gender
    • Kessing LV. Recurrence in affective disorder. II. Effect of age and gender. Br J Psychiatry 1998;172:29-34.
    • (1998) Br J Psychiatry , vol.172 , pp. 29-34
    • Kessing, L.V.1
  • 9
    • 0033673747 scopus 로고    scopus 로고
    • Affective disorders and suicide risk: A reexamination
    • Bostwick JM, Pankratz VS. Affective disorders and suicide risk: a reexamination. Am J Psychiatry 2000;157:1925-1932.
    • (2000) Am J Psychiatry , vol.157 , pp. 1925-1932
    • Bostwick, J.M.1    Pankratz, V.S.2
  • 10
    • 0036325685 scopus 로고    scopus 로고
    • Beyond the monoamine hypothesis: Mecha-nisms, molecules and methods
    • Hindmarch I. Beyond the monoamine hypothesis: mecha-nisms, molecules and methods. Eur Psychiatry 2002;17 Suppl 3:294-299.
    • (2002) Eur Psychiatry , vol.17 , Issue.SUPPL. 3 , pp. 294-299
    • Hindmarch, I.1
  • 11
    • 2142822259 scopus 로고    scopus 로고
    • Selectivity of antidepressants: From the monoam-ine hypothesis of depression to the SSRI revolution and beyond
    • Owens MJ. Selectivity of antidepressants: from the monoam-ine hypothesis of depression to the SSRI revolution and beyond. J Clin Psychiatry 2004;65 Suppl 4:5-10.
    • (2004) J Clin Psychiatry , vol.65 , Issue.SUPPL. 4 , pp. 5-10
    • Owens, M.J.1
  • 12
    • 38349049478 scopus 로고    scopus 로고
    • Selective publication of antidepressant trials and its influence on apparent efficacy
    • Turner EH, Matthews AM, Linardatos E, Tell RA, Rosenthal R. Selective publication of antidepressant trials and its influence on apparent efficacy. N Engl J Med 2008;358:252-260.
    • (2008) N Engl J Med , vol.358 , pp. 252-260
    • Turner, E.H.1    Matthews, A.M.2    Linardatos, E.3    Tell, R.A.4    Rosenthal, R.5
  • 13
    • 60849086169 scopus 로고    scopus 로고
    • Comparative efficacy and acceptability of 12 new-generation antidepressants: A multi-ple-treatments meta-analysis
    • Cipriani A, Furukawa TA, Salanti G et al. Comparative efficacy and acceptability of 12 new-generation antidepressants: a multi-ple-treatments meta-analysis. Lancet 2009.
    • (2009) Lancet
    • Cipriani, A.1    Furukawa, T.A.2    Salanti, G.3
  • 14
    • 73449112663 scopus 로고    scopus 로고
    • Antidepressant drug effects and depression severity: A patient-level meta-analysis
    • Fournier JC, DeRubeis RJ, Hollon SD et al. Antidepressant drug effects and depression severity: a patient-level meta-analysis. JAMA 2010;303:47-53.
    • (2010) JAMA , vol.303 , pp. 47-53
    • Fournier, J.C.1    DeRubeis, R.J.2    Hollon, S.D.3
  • 15
    • 62449259744 scopus 로고    scopus 로고
    • Improving the prediction of treatment response in depression: Integration of clinical, cognitive, psychophysiological, neuroimaging, and genetic measures
    • Kemp AH, Gordon E, Rush AJ, Williams LM. Improving the prediction of treatment response in depression: integration of clinical, cognitive, psychophysiological, neuroimaging, and genetic measures. CNS Spectr 2008;13:1066-1086.
    • (2008) CNS Spectr , vol.13 , pp. 1066-1086
    • Kemp, A.H.1    Gordon, E.2    Rush, A.J.3    Williams, L.M.4
  • 16
    • 0036294126 scopus 로고    scopus 로고
    • Efficacy of citalo-pram in the prevention of recurrent depression in elderly patients: Placebo-controlled study of maintenance therapy
    • Klysner R, Bent-Hansen J, Hansen HL et al. Efficacy of citalo-pram in the prevention of recurrent depression in elderly patients: placebo-controlled study of maintenance therapy. Br J Psychiatry 2002;181:29-35.
    • (2002) Br J Psychiatry , vol.181 , pp. 29-35
    • Klysner, R.1    Bent-Hansen, J.2    Hansen, H.L.3
  • 17
    • 0037460745 scopus 로고    scopus 로고
    • Relapse prevention with antidepressant drug treatment in depressive disorders: A system-atic review
    • Geddes JR, Carney SM, Davies C et al. Relapse prevention with antidepressant drug treatment in depressive disorders: a system-atic review. Lancet 2003;361:653-661.
    • (2003) Lancet , vol.361 , pp. 653-661
    • Geddes, J.R.1    Carney, S.M.2    Davies, C.3
  • 18
    • 27644462579 scopus 로고    scopus 로고
    • Experimental medicine in psychiatry
    • Dawson GR, Goodwin G. Experimental medicine in psychiatry. J Psychopharmacol 2005;19:565-566.
    • (2005) J Psychopharmacol , vol.19 , pp. 565-566
    • Dawson, G.R.1    Goodwin, G.2
  • 19
    • 0033810465 scopus 로고    scopus 로고
    • Genetic epidemiology of major depression: Review and meta-analysis
    • Sullivan PF, Neale MC, Kendler KS. Genetic epidemiology of major depression: review and meta-analysis. Am J Psychiatry 2000;157:1552-1562.
    • (2000) Am J Psychiatry , vol.157 , pp. 1552-1562
    • Sullivan, P.F.1    Neale, M.C.2    Kendler, K.S.3
  • 21
    • 1042289323 scopus 로고    scopus 로고
    • Exposure to postnatal depression predicts elevated cortisol in adolescent offspring
    • Halligan SL, Herbert J, Goodyer IM, Murray L. Exposure to postnatal depression predicts elevated cortisol in adolescent offspring. Biol Psychiatry 2004;55:376-381.
    • (2004) Biol Psychiatry , vol.55 , pp. 376-381
    • Halligan, S.L.1    Herbert, J.2    Goodyer, I.M.3    Murray, L.4
  • 22
    • 0031885081 scopus 로고    scopus 로고
    • Hormonal response pattern in the combined DEX-CRH test is stable over time in subjects at high familial risk for affective dis-orders
    • Modell S, Lauer CJ, Schreiber W, Huber J, Krieg JC, Holsboer F. Hormonal response pattern in the combined DEX-CRH test is stable over time in subjects at high familial risk for affective dis-orders. Neuropsychopharmacology 1998;18:253-262.
    • (1998) Neuropsychopharmacology , vol.18 , pp. 253-262
    • Modell, S.1    Lauer, C.J.2    Schreiber, W.3    Huber, J.4    Krieg, J.C.5    Holsboer, F.6
  • 24
  • 25
    • 33749357022 scopus 로고    scopus 로고
    • Personality and major depression: A Swedish longitudinal, population-based twin study
    • Kendler KS, Gatz M, Gardner CO, Pedersen NL. Personality and major depression: a Swedish longitudinal, population-based twin study. Arch Gen Psychiatry 2006;63:1113-1120.
    • (2006) Arch Gen Psychiatry , vol.63 , pp. 1113-1120
    • Kendler, K.S.1    Gatz, M.2    Gardner, C.O.3    Pedersen, N.L.4
  • 26
    • 33746176447 scopus 로고    scopus 로고
    • Cognitive function in unaffected twins discordant for affective disorder
    • Christensen MV, Kyvik KO, Kessing LV. Cognitive function in unaffected twins discordant for affective disorder. Psychol Med 2006;36:1119-1129.
    • (2006) Psychol Med , vol.36 , pp. 1119-1129
    • Christensen, M.V.1    Kyvik, K.O.2    Kessing, L.V.3
  • 27
    • 34548512783 scopus 로고    scopus 로고
    • Impaired emo-tional categorisation in young people at increased familial risk of depression
    • Mannie ZN, Bristow GC, Harmer CJ, Cowen PJ. Impaired emo-tional categorisation in young people at increased familial risk of depression. Neuropsychologia 2007;45:2975-2980.
    • (2007) Neuropsychologia , vol.45 , pp. 2975-2980
    • Mannie, Z.N.1    Bristow, G.C.2    Harmer, C.J.3    Cowen, P.J.4
  • 28
    • 66849134878 scopus 로고    scopus 로고
    • Mem-ory impairment in young women at increased risk of depression: Influence of cortisol and 5-HTT genotype
    • Mannie ZN, Barnes J, Bristow GC, Harmer CJ, Cowen PJ. Mem-ory impairment in young women at increased risk of depression: influence of cortisol and 5-HTT genotype. Psychol Med 2009;39:757-762.
    • (2009) Psychol Med , vol.39 , pp. 757-762
    • Mannie, Z.N.1    Barnes, J.2    Bristow, G.C.3    Harmer, C.J.4    Cowen, P.J.5
  • 29
    • 77952125504 scopus 로고    scopus 로고
    • The effect of selective serotonin reuptake inhibitors in healthy subjects. A systematic review
    • Knorr U, Kessing LV. The effect of selective serotonin reuptake inhibitors in healthy subjects. A systematic review. Nord J Psychiatry 2010.
    • (2010) Nord J Psychiatry
    • Knorr, U.1    Kessing, L.V.2
  • 30
    • 0033797445 scopus 로고    scopus 로고
    • The corticosteroid receptor hypothesis of depres-sion
    • Holsboer F. The corticosteroid receptor hypothesis of depres-sion. Neuropsychopharmacology 2000;23:477-501.
    • (2000) Neuropsychopharmacology , vol.23 , pp. 477-501
    • Holsboer, F.1
  • 32
    • 0024992869 scopus 로고
    • Serotonin receptor subtypes involved in the elevation of serum corticosterone concentration in rats by direct-and indirect-acting serotonin agonists
    • Fuller RW, Snoddy HD. Serotonin receptor subtypes involved in the elevation of serum corticosterone concentration in rats by direct-and indirect-acting serotonin agonists. Neuroendocrinol-ogy 1990;52:206-211.
    • (1990) Neuroendocrinol-ogy , vol.52 , pp. 206-211
    • Fuller, R.W.1    Snoddy, H.D.2
  • 33
    • 0032980914 scopus 로고    scopus 로고
    • Acute and long-term treatments with the selective sero-tonin reuptake inhibitor citalopram modulate the HPA axis activ-ity at different levels in male rats
    • Jensen JB, Jessop DS, Harbuz MS, Mork A, Sanchez C, Mikkel-sen JD. Acute and long-term treatments with the selective sero-tonin reuptake inhibitor citalopram modulate the HPA axis activ-ity at different levels in male rats. J Neuroendocrinol 1999;11:465-471.
    • (1999) J Neuroendocrinol , vol.11 , pp. 465-471
    • Jensen, J.B.1    Jessop, D.S.2    Harbuz, M.S.3    Mork, A.4    Sanchez, C.5    Mikkelsen, J.D.6
  • 34
    • 0029879868 scopus 로고    scopus 로고
    • Neuroendocrine effects of a 20-mg citalopram infusion in healthy males. A placebo-controlled evaluation of citalopram as 5-HT function probe
    • Seifritz E, Baumann P, Muller MJ et al. Neuroendocrine effects of a 20-mg citalopram infusion in healthy males. A placebo-controlled evaluation of citalopram as 5-HT function probe. Neu-ropsychopharmacology 1996;14:253-263.
    • (1996) Neu-ropsychopharmacology , vol.14 , pp. 253-263
    • Seifritz, E.1    Baumann, P.2    Muller, M.J.3
  • 35
    • 0036373028 scopus 로고    scopus 로고
    • Acute citalopram administra-tion produces correlated increases in plasma and salivary cortisol
    • Bhagwagar Z, Hafizi S, Cowen PJ. Acute citalopram administra-tion produces correlated increases in plasma and salivary cortisol. Psychopharmacology (Berl) 2002;163:118-120.
    • (2002) Psychopharmacology (Berl) , vol.163 , pp. 118-120
    • Bhagwagar, Z.1    Hafizi, S.2    Cowen, P.J.3
  • 36
    • 12144263105 scopus 로고    scopus 로고
    • Four days of citalopram increase suppression of cortisol secretion by predniso-lone in healthy volunteers
    • Pariante CM, Papadopoulos AS, Poon L et al. Four days of citalopram increase suppression of cortisol secretion by predniso-lone in healthy volunteers. Psychopharmacology (Berl) 2004;177:200-206.
    • (2004) Psychopharmacology (Berl) , vol.177 , pp. 200-206
    • Pariante, C.M.1    Papadopoulos, A.S.2    Poon, L.3
  • 37
    • 4344698012 scopus 로고    scopus 로고
    • Comparison of the effects of citalopram and escitalopram on 5-Ht-mediated neuro-endocrine responses
    • Nadeem HS, Attenburrow MJ, Cowen PJ. Comparison of the effects of citalopram and escitalopram on 5-Ht-mediated neuro-endocrine responses. Neuropsychopharmacology 2004;29:1699-1703.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1699-1703
    • Nadeem, H.S.1    Attenburrow, M.J.2    Cowen, P.J.3
  • 40
    • 77954346931 scopus 로고    scopus 로고
    • The genetic and environmental relation-ship between major depression and the five-factor model of personality
    • Kendler KS, Myers J. The genetic and environmental relation-ship between major depression and the five-factor model of personality. Psychol Med 2009;1-6.
    • (2009) Psychol Med , pp. 1-6
    • Kendler, K.S.1    Myers, J.2
  • 43
    • 52149083001 scopus 로고    scopus 로고
    • Neuroticism as a mediator of treatment response to SSRIs in major depressive disorder
    • Quilty LC, Meusel LA, Bagby RM. Neuroticism as a mediator of treatment response to SSRIs in major depressive disorder. J Affect Disord 2008;111:67-73.
    • (2008) J Affect Disord , vol.111 , pp. 67-73
    • Quilty, L.C.1    Meusel, L.A.2    Bagby, R.M.3
  • 44
    • 34548189842 scopus 로고    scopus 로고
    • Relationship between neuroticism personality trait and serotonin transporter binding
    • Takano A, Arakawa R, Hayashi M, Takahashi H, Ito H, Suhara T. Relationship between neuroticism personality trait and serotonin transporter binding. Biol Psychiatry 2007;62:588-592.
    • (2007) Biol Psychiatry , vol.62 , pp. 588-592
    • Takano, A.1    Arakawa, R.2    Hayashi, M.3    Takahashi, H.4    Ito, H.5    Suhara, T.6
  • 45
    • 64049090374 scopus 로고    scopus 로고
    • High familial risk for mood disorder is associated with low dorsolateral prefrontal cortex serotonin transporter binding
    • Frokjaer VG, Vinberg M, Erritzoe D et al. High familial risk for mood disorder is associated with low dorsolateral prefrontal cortex serotonin transporter binding. Neuroimage 2009.
    • (2009) Neuroimage
    • Frokjaer, V.G.1    Vinberg, M.2    Erritzoe, D.3
  • 46
    • 0031894504 scopus 로고    scopus 로고
    • Selective alteration of personality and social behavior by serotonergic intervention
    • Knutson B, Wolkowitz OM, Cole SW et al. Selective alteration of personality and social behavior by serotonergic intervention. Am J Psychiatry 1998;155:373-379.
    • (1998) Am J Psychiatry , vol.155 , pp. 373-379
    • Knutson, B.1    Wolkowitz, O.M.2    Cole, S.W.3
  • 47
    • 0034869438 scopus 로고    scopus 로고
    • Serotonergic involvement in the psychoso-cial dimension of personality
    • Tse WS, Bond AJ. Serotonergic involvement in the psychoso-cial dimension of personality. J Psychopharmacol 2001;15:195-198.
    • (2001) J Psychopharmacol , vol.15 , pp. 195-198
    • Tse, W.S.1    Bond, A.J.2
  • 48
    • 0022589659 scopus 로고
    • Mini-compendium of rating scales for states of anxiety depression mania schizophrenia with corresponding DSM-III syndromes
    • Bech P, Kastrup M, Rafaelsen OJ. Mini-compendium of rating scales for states of anxiety depression mania schizophrenia with corresponding DSM-III syndromes. Acta Psychiatr Scand Suppl 1986;326:1-37.
    • (1986) Acta Psychiatr Scand Suppl , vol.326 , pp. 1-37
    • Bech, P.1    Kastrup, M.2    Rafaelsen, O.J.3
  • 50
    • 33646087196 scopus 로고    scopus 로고
    • Antidepressant drug treatment modifies the neural processing of nonconscious threat cues
    • Harmer CJ, Mackay CE, Reid CB, Cowen PJ, Goodwin GM. Antidepressant drug treatment modifies the neural processing of nonconscious threat cues. Biol Psychiatry 2006;59:816-820.
    • (2006) Biol Psychiatry , vol.59 , pp. 816-820
    • Harmer, C.J.1    McKay, C.E.2    Reid, C.B.3    Cowen, P.J.4    Goodwin, G.M.5
  • 51
    • 0035991076 scopus 로고    scopus 로고
    • Serotonergic intervention affects both social dominance and affiliative behaviour
    • Tse WS, Bond AJ. Serotonergic intervention affects both social dominance and affiliative behaviour. Psychopharmacology (Berl) 2002;161:324-330.
    • (2002) Psychopharmacology (Berl) , vol.161 , pp. 324-330
    • Tse, W.S.1    Bond, A.J.2
  • 52
    • 0038201785 scopus 로고    scopus 로고
    • Fluvoxamine modulates pain sensation and affective processing of pain in human brain
    • Nemoto H, Toda H, Nakajima T et al. Fluvoxamine modulates pain sensation and affective processing of pain in human brain. Neuroreport 2003;14:791-797.
    • (2003) Neuroreport , vol.14 , pp. 791-797
    • Nemoto, H.1    Toda, H.2    Nakajima, T.3
  • 53
    • 58149101858 scopus 로고    scopus 로고
    • Personality traits in children of parents with unipolar and bipolar mood disor-ders
    • Rothen S, Vandeleur CL, Lustenberger Y et al. Personality traits in children of parents with unipolar and bipolar mood disor-ders. J Affect Disord 2009;113:133-141.
    • (2009) J Affect Disord , vol.113 , pp. 133-141
    • Rothen, S.1    Vandeleur, C.L.2    Lustenberger, Y.3
  • 54
    • 33646109812 scopus 로고    scopus 로고
    • Do personality traits predict first onset in depressive and bipolar disorder?
    • Christensen MV, Kessing LV. Do personality traits predict first onset in depressive and bipolar disorder? Nord J Psychiatry 2006;60:79-88.
    • (2006) Nord J Psychiatry , vol.60 , pp. 79-88
    • Christensen, M.V.1    Kessing, L.V.2
  • 56
    • 0035118639 scopus 로고    scopus 로고
    • Possible implications for functional neuropathology
    • possible implications for functional neuropathology. Br J Psychiatry 2001;178:200-206.
    • (2001) Br J Psychiatry , vol.178 , pp. 200-206
  • 57
    • 0031696978 scopus 로고    scopus 로고
    • Cognitive impairment in the euthymic phase of affective disorder
    • Kessing LV. Cognitive impairment in the euthymic phase of affective disorder. Psychol Med 1998;28:1027-1038.
    • (1998) Psychol Med , vol.28 , pp. 1027-1038
    • Kessing, L.V.1
  • 59
    • 68549099709 scopus 로고    scopus 로고
    • Why do antidepressants take so long to work? A cognitive neuropsychological model of antidepressant drug action
    • Harmer CJ, Goodwin GM, Cowen PJ. Why do antidepressants take so long to work? A cognitive neuropsychological model of antidepressant drug action. Br J Psychiatry 2009;195:102-108.
    • (2009) Br J Psychiatry , vol.195 , pp. 102-108
    • Harmer, C.J.1    Goodwin, G.M.2    Cowen, P.J.3
  • 60
    • 70349638309 scopus 로고    scopus 로고
    • Effect of acute anti-depressant administration on negative affective bias in depressed patients
    • Harmer CJ, O'Sullivan U, Favaron E et al. Effect of acute anti-depressant administration on negative affective bias in depressed patients. Am J Psychiatry 2009;166:1178-1184.
    • (2009) Am J Psychiatry , vol.166 , pp. 1178-1184
    • Harmer, C.J.1    O'Sullivan, U.2    Favaron, E.3
  • 61
    • 34547843648 scopus 로고    scopus 로고
    • Single dose antidepressant administration modulates the neural processing of self-referent personality trait words
    • Miskowiak K, Papadatou-Pastou M, Cowen PJ, Goodwin GM, Norbury R, Harmer CJ. Single dose antidepressant administration modulates the neural processing of self-referent personality trait words. Neuroimage 2007;37:904-911.
    • (2007) Neuroimage , vol.37 , pp. 904-911
    • Miskowiak, K.1    Papadatou-Pastou, M.2    Cowen, P.J.3    Goodwin, G.M.4    Norbury, R.5    Harmer, C.J.6
  • 62
    • 69749088328 scopus 로고    scopus 로고
    • Rationale and design of the participant, investigator, observer, and data-analyst-blinded randomized AGENDA trial on associations between gene-polymorphisms, endophenotypes for depression and antidepres-sive intervention
    • The effect of escitalopram versus placebo on the combined dexamethasone-corticotrophine releasing hormone test and other potential endophenotypes in healthy first-degree relatives of persons with depression
    • Knorr U, Vinberg M, Klose M et al. Rationale and design of the participant, investigator, observer, and data-analyst-blinded randomized AGENDA trial on associations between gene-polymorphisms, endophenotypes for depression and antidepres-sive intervention: the effect of escitalopram versus placebo on the combined dexamethasone-corticotrophine releasing hormone test and other potential endophenotypes in healthy first-degree relatives of persons with depression. Trials 2009;10:66.
    • (2009) Trials , vol.10 , pp. 66
    • Knorr, U.1    Vinberg, M.2    Klose, M.3
  • 63
    • 84873157686 scopus 로고    scopus 로고
    • ICH Harmonised Tripartite Guideline for Good Clinical Practice (CPMP/ICH/135/95), 10-5-2006. 10-5-2006. Ref Type: Internet Communication
    • ICH Harmonised Tripartite Guideline for Good Clinical Practice (CPMP/ICH/135/95), www.emea.int/pdfs/human/ich/013595en/pdf. 10-5-2006. 10-5-2006. Ref Type: Internet Communication
  • 64
    • 0025439099 scopus 로고
    • SCAN. Schedules for Clinical Assessment in Neuropsychiatry
    • Wing JK, Babor T, Brugha T et al. SCAN. Schedules for Clinical Assessment in Neuropsychiatry. Arch Gen Psychiatry 1990;47:589-593.
    • (1990) Arch Gen Psychiatry , vol.47 , pp. 589-593
    • Wing, J.K.1    Babor, T.2    Brugha, T.3
  • 65
    • 0029802543 scopus 로고    scopus 로고
    • Blinding during data analysis and writing of manuscripts
    • Gotzsche PC. Blinding during data analysis and writing of manuscripts. Control Clin Trials 1996;17:285-290.
    • (1996) Control Clin Trials , vol.17 , pp. 285-290
    • Gotzsche, P.C.1
  • 66
    • 34547410247 scopus 로고    scopus 로고
    • Consensus paper of the WFSBP Task Force on Biological Markers: Biological markers in depression
    • Mossner R, Mikova O, Koutsilieri E et al. Consensus paper of the WFSBP Task Force on Biological Markers: biological markers in depression. World J Biol Psychiatry 2007;8:141-174.
    • (2007) World J Biol Psychiatry , vol.8 , pp. 141-174
    • Mossner, R.1    Mikova, O.2    Koutsilieri, E.3
  • 69
    • 0343145702 scopus 로고    scopus 로고
    • Stability and change in personality assessment: The revised NEO Personality Inventory in the year 2000
    • Costa PT, Jr., McCrae RR. Stability and change in personality assessment: the revised NEO Personality Inventory in the year 2000. J Pers Assess 1997;68:86-94.
    • (1997) J Pers Assess , vol.68 , pp. 86-94
    • Costa Jr., P.T.1    McCrae, R.R.2
  • 70
    • 0018099766 scopus 로고
    • Dementia: The estimation of premor-bid intelligence levels using the New Adult Reading Test
    • Nelson HE, O'Connell A. Dementia: the estimation of premor-bid intelligence levels using the New Adult Reading Test. Cortex 1978;14:234-244.
    • (1978) Cortex , vol.14 , pp. 234-244
    • Nelson, H.E.1    O'Connell, A.2
  • 71
    • 0028218597 scopus 로고
    • Heterogeneity of neocortical cerebral blood flow deficits in dementia of the Alzheimer type: A [99mTc]-d, l-HMPAO SPECT study
    • Waldemar G, Bruhn P, Kristensen M, Johnsen A, Paulson OB, Lassen NA. Heterogeneity of neocortical cerebral blood flow deficits in dementia of the Alzheimer type: a [99mTc]-d, l-HMPAO SPECT study. J Neurol Neurosurg Psychiatry 1994;57:285-295.
    • (1994) J Neurol Neurosurg Psychiatry , vol.57 , pp. 285-295
    • Waldemar, G.1    Bruhn, P.2    Kristensen, M.3    Johnsen, A.4    Paulson, O.B.5    Lassen, N.A.6
  • 72
    • 0003690749 scopus 로고
    • Manual for Administration and Scoring., 2920 South 4th Avenue, South Tucson, Arizona 85713-4819, Reitan Neuropsychology Laboratory. Ref Type: Serial (Book, Monograph)
    • Reitan RM. Trail Making Test. Manual for Administration and Scoring. 1992. 2920 South 4th Avenue, South Tucson, Arizona 85713-4819, Reitan Neuropsychology Laboratory. Ref Type: Serial (Book, Monograph)
    • (1992) Trail Making Test
    • Reitan, R.M.1
  • 75
    • 0023907926 scopus 로고
    • "Chronic painter's syn-drome". A reanalysis of psychological test data in a group of diagnosed cases, based on comparisons with matched controls
    • Gade A, Mortensen EL, Bruhn P. "Chronic painter's syn-drome". A reanalysis of psychological test data in a group of diagnosed cases, based on comparisons with matched controls. Acta Neurol Scand 1988;77:293-306.
    • (1988) Acta Neurol Scand , vol.77 , pp. 293-306
    • Gade, A.1    Mortensen, E.L.2    Bruhn, P.3
  • 76
    • 0023037928 scopus 로고
    • CAMDEX. A standardised instrument for the diagnosis of mental disorder in the elderly with special reference to the early detection of dementia
    • Roth M, Tym E, Mountjoy CQ et al. CAMDEX. A standardised instrument for the diagnosis of mental disorder in the elderly with special reference to the early detection of dementia. Br J Psychiatry 1986;149:698-709.
    • (1986) Br J Psychiatry , vol.149 , pp. 698-709
    • Roth, M.1    Tym, E.2    Mountjoy, C.Q.3
  • 77
    • 13444304183 scopus 로고    scopus 로고
    • Alternative forms of the Rey Auditory Verbal Learning Test: A review
    • Hawkins KA, Dean D, Pearlson GD. Alternative forms of the Rey Auditory Verbal Learning Test: a review. Behav Neurol 2004;15:99-107.
    • (2004) Behav Neurol , vol.15 , pp. 99-107
    • Hawkins, K.A.1    Dean, D.2    Pearlson, G.D.3
  • 78
    • 0029095754 scopus 로고
    • Developmental trends in visuospatial analysis and planning: Copying a complex figure
    • Akshoofmoff N, Stiles J. Developmental trends in visuospatial analysis and planning: Copying a complex figure. Neuropsychology 1995;9:364-377.
    • (1995) Neuropsychology , vol.9 , pp. 364-377
    • Akshoofmoff, N.1    Stiles, J.2
  • 79
    • 0032796864 scopus 로고    scopus 로고
    • Word fluency in aging and dementia: Principles of relatedness in the generative naming process
    • Yaretsky A, Arzi T, Ben-Nun Y. Word fluency in aging and dementia: principles of relatedness in the generative naming process. Arch Gerontol Geriatr 1999;29:57-60.
    • (1999) Arch Gerontol Geriatr , vol.29 , pp. 57-60
    • Yaretsky, A.1    Arzi, T.2    Ben-Nun, Y.3
  • 80
    • 29144511199 scopus 로고    scopus 로고
    • Normative Sym-bol Digit Modalities Test performance in a community-based sample
    • Sheridan LK, Fitzgerald HE, Adams KM et al. Normative Sym-bol Digit Modalities Test performance in a community-based sample. Arch Clin Neuropsychol 2006;21:23-28.
    • (2006) Arch Clin Neuropsychol , vol.21 , pp. 23-28
    • Sheridan, L.K.1    Fitzgerald, H.E.2    Adams, K.M.3
  • 81
    • 0034466803 scopus 로고    scopus 로고
    • Neural activation during performance of number-letter sequencing
    • Haut MW, Kuwabara H, Leach S, Arias RG. Neural activation during performance of number-letter sequencing. Appl Neuropsy-chol 2000;7:237-242.
    • (2000) Appl Neuropsy-chol , vol.7 , pp. 237-242
    • Haut, M.W.1    Kuwabara, H.2    Leach, S.3    Arias, R.G.4
  • 83
    • 0035163643 scopus 로고    scopus 로고
    • Patient-rated versus clinician-rated side effects of drug treatment in schizophrenia. Clinical validation of a self-rating version of the UKU Side Effect Rating Scale (UKU-SERS-Pat)
    • Lindstrom E, Lewander T, Malm U, Malt UF, Lublin H, Ahlfors UG. Patient-rated versus clinician-rated side effects of drug treatment in schizophrenia. Clinical validation of a self-rating version of the UKU Side Effect Rating Scale (UKU-SERS-Pat). Nord J Psychiatry 2001;55 Suppl 44:5-69.
    • (2001) Nord J Psychiatry , vol.55 , Issue.SUPPL. 44 , pp. 5-69
    • Lindstrom, E.1    Lewander, T.2    Malm, U.3    Malt, U.F.4    Lublin, H.5    Ahlfors, U.G.6
  • 84
    • 0035841813 scopus 로고    scopus 로고
    • Statistics notes: Analysing controlled trials with baseline and follow up measurements
    • Vickers AJ, Altman DG. Statistics notes: Analysing controlled trials with baseline and follow up measurements. BMJ 2001;323:1123-1124.
    • (2001) BMJ , vol.323 , pp. 1123-1124
    • Vickers, A.J.1    Altman, D.G.2
  • 85
    • 84873159429 scopus 로고    scopus 로고
    • ICH Harmonised Tripartite Guideline for Good Clinical Practice (CPMP/ICH/135/95), 10-5-2006. 10-5-2006. Ref Type: Internet Communication
    • ICH Harmonised Tripartite Guideline for Good Clinical Practice (CPMP/ICH/135/95), www.emea.int/pdfs/human/ich/013595en/pdf. 10-5-2006. 10-5-2006. Ref Type: Internet Communication
  • 86
    • 77149146771 scopus 로고    scopus 로고
    • The combined dexa-methasone/CRH Test (DEX/CRH test) and prediction of acute treatment response in major depression
    • Schule C, Baghai TC, Eser D et al. The combined dexa-methasone/CRH Test (DEX/CRH test) and prediction of acute treatment response in major depression. PLoS One 2009;4:e4324.
    • (2009) PLoS One , vol.4
    • Schule, C.1    Baghai, T.C.2    Eser, D.3
  • 87
    • 0036346113 scopus 로고    scopus 로고
    • Does fluoxetine influence major depression by modifying five-factor personality traits?
    • Du L, Bakish D, Ravindran AV, Hrdina PD. Does fluoxetine influence major depression by modifying five-factor personality traits? J Affect Disord 2002;71:235-241.
    • (2002) J Affect Disord , vol.71 , pp. 235-241
    • Du, L.1    Bakish, D.2    Ravindran, A.V.3    Hrdina, P.D.4
  • 88
    • 0030998792 scopus 로고    scopus 로고
    • Citalo-pram Compared to Dothiepin and Placebo: Effects on Cognitive Function and Psychomotor Performance
    • Fairweather D, Pozzo C, Kerr J, Lafferty S, Hindmarch I. Citalo-pram Compared to Dothiepin and Placebo: effects on Cognitive Function and Psychomotor Performance. Human Psychopharma-cology 1997;12:119-126.
    • (1997) Human Psychopharma-cology , vol.12 , pp. 119-126
    • Fairweather, D.1    Pozzo, C.2    Kerr, J.3    Lafferty, S.4    Hindmarch, I.5
  • 89
    • 0034874581 scopus 로고    scopus 로고
    • Non-serotonergic phar-macological profiles and associated cognitive effects of serotonin reuptake inhibitors
    • Schmitt JA, Kruizinga MJ, Riedel WJ. Non-serotonergic phar-macological profiles and associated cognitive effects of serotonin reuptake inhibitors. J Psychopharmacol 2001;15:173-179.
    • (2001) J Psychopharmacol , vol.15 , pp. 173-179
    • Schmitt, J.A.1    Kruizinga, M.J.2    Riedel, W.J.3
  • 90
    • 23044502894 scopus 로고    scopus 로고
    • Modulation of behav-ior and cortical motor activity in healthy subjects by a chronic administration of a serotonin enhancer
    • Loubinoux I, Tombari D, Pariente J et al. Modulation of behav-ior and cortical motor activity in healthy subjects by a chronic administration of a serotonin enhancer. Neuroimage 2005;27:299-313.
    • (2005) Neuroimage , vol.27 , pp. 299-313
    • Loubinoux, I.1    Tombari, D.2    Pariente, J.3
  • 91
    • 0028913048 scopus 로고
    • Acute and subchronic effects of paroxetine 20 and 40 mg on actual driving, psychomotor per-formance and subjective assessments in healthy volunteers
    • Robbe HW, O'Hanlon JF. Acute and subchronic effects of paroxetine 20 and 40 mg on actual driving, psychomotor per-formance and subjective assessments in healthy volunteers. Eur Neuropsychopharmacol 1995;5:35-42.
    • (1995) Eur Neuropsychopharmacol , vol.5 , pp. 35-42
    • Robbe, H.W.1    O'Hanlon, J.F.2
  • 92
    • 12444312895 scopus 로고    scopus 로고
    • Specific seroton-ergic reuptake inhibition impairs vigilance performance acutely and after subchronic treatment
    • Riedel WJ, Eikmans K, Heldens A, Schmitt JA. Specific seroton-ergic reuptake inhibition impairs vigilance performance acutely and after subchronic treatment. J Psychopharmacol 2005;19:12-20.
    • (2005) J Psychopharmacol , vol.19 , pp. 12-20
    • Riedel, W.J.1    Eikmans, K.2    Heldens, A.3    Schmitt, J.A.4
  • 93
    • 0028965726 scopus 로고
    • A comparative study of acute and subchronic effects of dothiepin, fluoxetine and placebo on psychomotor and actual driving performance
    • Ramaekers JG, Muntjewerff ND, O'Hanlon JF. A comparative study of acute and subchronic effects of dothiepin, fluoxetine and placebo on psychomotor and actual driving performance. Br J Clin Pharmacol 1995;39:397-404.
    • (1995) Br J Clin Pharmacol , vol.39 , pp. 397-404
    • Ramaekers, J.G.1    Muntjewerff, N.D.2    O'Hanlon, J.F.3
  • 95
    • 33750505623 scopus 로고    scopus 로고
    • Verbal memory perform-ance during subchronic challenge with a selective serotonergic and a mixed action antidepressant
    • Wingen M, Langer S, Ramaekers JG. Verbal memory perform-ance during subchronic challenge with a selective serotonergic and a mixed action antidepressant. Hum Psychopharmacol 2006;21:473-479.
    • (2006) Hum Psychopharmacol , vol.21 , pp. 473-479
    • Wingen, M.1    Langer, S.2    Ramaekers, J.G.3
  • 96
    • 0036787783 scopus 로고    scopus 로고
    • The impact of sertraline on psy-chomotor performance
    • Paul MA, Gray G, Lange M. The impact of sertraline on psy-chomotor performance. Aviat Space Environ Med 2002;73:964-970.
    • (2002) Aviat Space Environ Med , vol.73 , pp. 964-970
    • Paul, M.A.1    Gray, G.2    Lange, M.3
  • 97
    • 34447257932 scopus 로고    scopus 로고
    • SSRI effects on pyscho-motor performance: Assessment of citalopram and escitalopram on normal subjects
    • Paul MA, Gray GW, Love RJ, Lange M. SSRI effects on pyscho-motor performance: assessment of citalopram and escitalopram on normal subjects. Aviat Space Environ Med 2007;78:693-697.
    • (2007) Aviat Space Environ Med , vol.78 , pp. 693-697
    • Paul, M.A.1    Gray, G.W.2    Love, R.J.3    Lange, M.4
  • 98
    • 17844400947 scopus 로고    scopus 로고
    • Actual driving performance and psychomotor function in healthy subjects after acute and subchronic treatment with escitalopram, mirtazapine, and placebo: A crossover trial
    • Wingen M, Bothmer J, Langer S, Ramaekers JG. Actual driving performance and psychomotor function in healthy subjects after acute and subchronic treatment with escitalopram, mirtazapine, and placebo: a crossover trial. J Clin Psychiatry 2005;66:436-443.
    • (2005) J Clin Psychiatry , vol.66 , pp. 436-443
    • Wingen, M.1    Bothmer, J.2    Langer, S.3    Ramaekers, J.G.4
  • 99
    • 0023880171 scopus 로고
    • A comparative study of the interactions of alcohol with amitriptyline, fluoxetine and placebo in normal subjects
    • Allen D, Lader M, Curran HV. A comparative study of the interactions of alcohol with amitriptyline, fluoxetine and placebo in normal subjects. Prog Neuropsychopharmacol Biol Psychiatry 1988;12:63-80.
    • (1988) Prog Neuropsychopharmacol Biol Psychiatry , vol.12 , pp. 63-80
    • Allen, D.1    Lader, M.2    Curran, H.V.3
  • 100
    • 0036904146 scopus 로고    scopus 로고
    • Effects of 5 weeks of administration of fluoxetine and dothiepin in normal volunteers on sleep, daytime sedation, psychomotor performance and mood
    • Wilson SJ, Bailey JE, Alford C, Weinstein A, Nutt DJ. Effects of 5 weeks of administration of fluoxetine and dothiepin in normal volunteers on sleep, daytime sedation, psychomotor performance and mood. J Psychopharmacol 2002;16:321-331.
    • (2002) J Psychopharmacol , vol.16 , pp. 321-331
    • Wilson, S.J.1    Bailey, J.E.2    Alford, C.3    Weinstein, A.4    Nutt, D.J.5
  • 101
    • 36348951596 scopus 로고    scopus 로고
    • Paroxetine-induced modu-lation of cortical activity supporting language representations of action
    • Peran P, Demonet JF, Cardebat D. Paroxetine-induced modu-lation of cortical activity supporting language representations of action. Psychopharmacology (Berl) 2008;195:487-496.
    • (2008) Psychopharmacology (Berl) , vol.195 , pp. 487-496
    • Peran, P.1    Demonet, J.F.2    Cardebat, D.3
  • 102
    • 0036209806 scopus 로고    scopus 로고
    • Modulation of the critical flicker fusion effects of serotonin reuptake inhibitors by concomitant pupillary changes
    • Schmitt JA, Riedel WJ, Vuurman EF, Kruizinga M, Ramaekers JG. Modulation of the critical flicker fusion effects of serotonin reuptake inhibitors by concomitant pupillary changes. Psy-chopharmacology (Berl) 2002;160:381-386.
    • (2002) Psy-chopharmacology (Berl) , vol.160 , pp. 381-386
    • Schmitt, J.A.1    Riedel, W.J.2    Vuurman, E.F.3    Kruizinga, M.4    Ramaekers, J.G.5
  • 103
    • 0043168086 scopus 로고    scopus 로고
    • Effects of sertraline on autonomic and cognitive functions in healthy volunteers
    • Siepmann M, Grossmann J, Muck-Weymann M, Kirch W. Effects of sertraline on autonomic and cognitive functions in healthy volunteers. Psychopharmacology (Berl) 2003;168:293-298.
    • (2003) Psychopharmacology (Berl) , vol.168 , pp. 293-298
    • Siepmann, M.1    Grossmann, J.2    Muck-Weymann, M.3    Kirch, W.4
  • 104
    • 70449376992 scopus 로고    scopus 로고
    • Differential effects of escitalopram on attention: A placebo-controlled, double-blind cross-over study
    • Drueke B, Baetz J, Boecker M et al. Differential effects of escitalopram on attention: a placebo-controlled, double-blind cross-over study. Psychopharmacology (Berl) 2009.
    • (2009) Psychopharmacology (Berl)
    • Drueke, B.1    Baetz, J.2    Boecker, M.3
  • 105
    • 0027988726 scopus 로고
    • The combined dexa-methasone/CRH test: A refined laboratory test for psychiatric disorders
    • Heuser I, Yassouridis A, Holsboer F. The combined dexa-methasone/CRH test: a refined laboratory test for psychiatric disorders. J Psychiatr Res 1994;28:341-356.
    • (1994) J Psychiatr Res , vol.28 , pp. 341-356
    • Heuser, I.1    Yassouridis, A.2    Holsboer, F.3
  • 106
    • 32844462857 scopus 로고    scopus 로고
    • Assessment of the dexa-methasone/CRH test as a state-dependent marker for hypotha-lamic-pituitary-adrenal (HPA) axis abnormalities in major depres-sive episode: A Multicenter Study
    • Kunugi H, Ida I, Owashi T et al. Assessment of the dexa-methasone/CRH test as a state-dependent marker for hypotha-lamic-pituitary-adrenal (HPA) axis abnormalities in major depres-sive episode: a Multicenter Study. Neuropsychopharmacology 2006;31:212-220.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 212-220
    • Kunugi, H.1    Ida, I.2    Owashi, T.3
  • 107
    • 0035450364 scopus 로고    scopus 로고
    • Second-generation SSRIs: Human monoamine transporter binding profile of escitalo-pram and R-fluoxetine
    • Owens MJ, Knight DL, Nemeroff CB. Second-generation SSRIs: human monoamine transporter binding profile of escitalo-pram and R-fluoxetine. Biol Psychiatry 2001;50:345-350.
    • (2001) Biol Psychiatry , vol.50 , pp. 345-350
    • Owens, M.J.1    Knight, D.L.2    Nemeroff, C.B.3
  • 108
    • 34147172443 scopus 로고    scopus 로고
    • Factors influencing the adrenocorticotropin test: Role of contemporary cortisol as-says, body composition, and oral contraceptive agents
    • Klose M, Lange M, Rasmussen AK et al. Factors influencing the adrenocorticotropin test: role of contemporary cortisol as-says, body composition, and oral contraceptive agents. J Clin Endocrinol Metab 2007;92:1326-1333.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 1326-1333
    • Klose, M.1    Lange, M.2    Rasmussen, A.K.3
  • 109
    • 33746882420 scopus 로고    scopus 로고
    • Effective dose of escitalopram in moderate versus severe DSM-IV major depression
    • Bech P, Andersen HF, Wade A. Effective dose of escitalopram in moderate versus severe DSM-IV major depression. Pharma-copsychiatry 2006;39:128-134.
    • (2006) Pharma-copsychiatry , vol.39 , pp. 128-134
    • Bech, P.1    Andersen, H.F.2    Wade, A.3
  • 110
    • 32444441010 scopus 로고    scopus 로고
    • The culture of designing hepato-biliary randomised trials
    • Gluud C. The culture of designing hepato-biliary randomised trials. J Hepatol 2006;44:607-615.
    • (2006) J Hepatol , vol.44 , pp. 607-615
    • Gluud, C.1
  • 111
    • 33644931936 scopus 로고    scopus 로고
    • Bias in clinical intervention research
    • Gluud LL. Bias in clinical intervention research. Am J Epide-miol 2006;163:493-501.
    • (2006) Am J Epide-miol , vol.163 , pp. 493-501
    • Gluud, L.L.1
  • 112
    • 38849162727 scopus 로고    scopus 로고
    • In the era of systematic reviews, does the size of an individual trial still matter
    • Guyatt GH, Mills EJ, Elbourne D. In the era of systematic reviews, does the size of an individual trial still matter. PLoS Med 2008;5:e4.
    • (2008) PLoS Med , vol.5
    • Guyatt, G.H.1    Mills, E.J.2    Elbourne, D.3
  • 113
    • 34047246293 scopus 로고    scopus 로고
    • Methodology of superiority vs. equivalence trials and non-inferiority trials
    • Christensen E. Methodology of superiority vs. equivalence trials and non-inferiority trials. J Hepatol 2007;46:947-954.
    • (2007) J Hepatol , vol.46 , pp. 947-954
    • Christensen, E.1
  • 114
    • 27844526619 scopus 로고    scopus 로고
    • The pharmacokinetics of escitalopram after oral and intravenous administration of single and multiple doses to healthy subjects
    • Sogaard B, Mengel H, Rao N, Larsen F. The pharmacokinetics of escitalopram after oral and intravenous administration of single and multiple doses to healthy subjects. J Clin Pharmacol 2005;45:1400-1406.
    • (2005) J Clin Pharmacol , vol.45 , pp. 1400-1406
    • Sogaard, B.1    Mengel, H.2    Rao, N.3    Larsen, F.4
  • 115
    • 25844518335 scopus 로고    scopus 로고
    • Long-term citalopram administration reduces responsiveness of HPA axis in patients with major depression: Relationship with S-citalopram concentra-tions in plasma and cerebrospinal fluid (CSF) and clinical re-sponse
    • Nikisch G, Mathe AA, Czernik A et al. Long-term citalopram administration reduces responsiveness of HPA axis in patients with major depression: relationship with S-citalopram concentra-tions in plasma and cerebrospinal fluid (CSF) and clinical re-sponse. Psychopharmacology (Berl) 2005;181:751-760.
    • (2005) Psychopharmacology (Berl) , vol.181 , pp. 751-760
    • Nikisch, G.1    Mathe, A.A.2    Czernik, A.3
  • 116
    • 0038823525 scopus 로고    scopus 로고
    • The endophenotype concept in psychiatry: Etymology and strategic intentions
    • Gottesman II, Gould TD. The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 2003;160:636-645.
    • (2003) Am J Psychiatry , vol.160 , pp. 636-645
    • Gottesman, I.I.1    Gould, T.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.