Nitric oxide activates intradomain disulfide bond formation in the kinase loop of Akt1/PKBα after burn injury

International Journal of Molecular Medicine

Volumn 31, Issue 3, 2013, Pages 740-750

  Lu, X M ^a,b,c   Tompkins, R G ^a,b,c   Fischman, Alan J ^b,c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c SHRINERS HOSPITALS FOR CHILDREN   (United States)

Author keywords

Akt1 protein kinase B ; Disulfide bond; MS MS; S nitrosylation

Indexed keywords

BIOTIN; CYSTEINE; NITRIC OXIDE; PROTEIN KINASE B; PROTEIN KINASE B ALPHA1; THREONINE; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BURN; CELL LYSATE; CONTROLLED STUDY; DISULFIDE BOND; ENZYME ACTIVATION; ENZYME INACTIVATION; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; NITROSYLATION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DEPHOSPHORYLATION; PROTEIN DOMAIN; PROTEIN ISOLATION; PROTEIN LOCALIZATION; QUADRUPOLE MASS SPECTROMETRY; RAT; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY; TRANSCRIPTION INITIATION;

ANIMALS; BURNS; CYSTEINE; DISULFIDES; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION; INFLAMMATION; INSULIN RECEPTOR SUBSTRATE PROTEINS; KINETICS; MUSCLE, SKELETAL; NITRIC OXIDE; PROTO-ONCOGENE PROTEINS C-AKT; RATS; S-NITROSOGLUTATHIONE;

EID: 84873112613     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2013.1241     Document Type: Article

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