Phosphoenolpyruvate, a glycolytic intermediate, as a cytoprotectant and antioxidant in ex-vivo cold-preserved mouse liver: A potential application for organ preservation

Journal of Pharmacy and Pharmacology

Volumn 65, Issue 3, 2013, Pages 390-401

  Kondo, Yuki ^a   Ishitsuka, Yoichi ^a   Kadowaki, Daisuke ^a   Fukumoto, Yusuke ^a   Miyamoto, Yohei ^a   Irikura, Mitsuru ^a   Hirata, Sumio ^a   Sato, Keizo ^b   Maruyama, Toru ^a   Hamasaki, Naotaka ^c   Irie, Tetsumi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY OF HEALTH AND WELFARE   (Japan)

^c NAGASAKI INTERNATIONAL UNIVERSITY   (Japan)

Author keywords

cellular injury; organ preservation; oxidative stress; phosphoenolpyruvate; transplantation

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMINOTRANSFERASE; GLUTATHIONE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; INDUCIBLE NITRIC OXIDE SYNTHASE; LACTATE DEHYDROGENASE; MESSENGER RNA; PHOSPHOENOLPYRUVATE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL STRAIN HEPG2; CONTROLLED STUDY; CRYOPRESERVATION; ELECTRON SPIN RESONANCE; EX VIVO STUDY; HISTOLOGY; IN VITRO STUDY; LIVER HOMOGENATE; LIVER INJURY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIOXIDANTS; CELL LINE, TUMOR; CRYOPRESERVATION; CRYOPROTECTIVE AGENTS; GLYCOLYSIS; HEP G2 CELLS; HUMANS; HYDROGEN PEROXIDE; L-LACTATE DEHYDROGENASE; LIVER; MALE; MICE; MICE, INBRED C57BL; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; ORGAN PRESERVATION; OXIDATIVE STRESS; PHOSPHOENOLPYRUVATE; REACTIVE OXYGEN SPECIES; SUPEROXIDES; TRANSAMINASES;

EID: 84873096837     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2012.01602.x     Document Type: Article

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