메뉴 건너뛰기




Volumn 50, Issue 1, 2013, Pages 1-20

Pathophysiology and treatment of diabetic retinopathy

Author keywords

Dexamethasone implant; Diabetic macular edema; Intravitreal anti VEGF; Laser; Proliferative diabetic retinopathy; Vitrectomy

Indexed keywords

ADVANCED GLYCATION END PRODUCT; AFLIBERCEPT; ALDOSTERONE; ANGIOTENSIN; ANGIOTENSIN II; BEVACIZUMAB; BEVASIRANIB; CHEMOKINE; CORTICOSTEROID; CYTOKINE; DEXAMETHASONE; FLUOCINOLONE ACETONIDE; GLUCOSE; ICOSANOID; INTERCELLULAR ADHESION MOLECULE 1; LIPID; NITRIC OXIDE; PEGAPTANIB; PLACEBO; POLYOL; PROTEIN KINASE C; RANIBIZUMAB; RAPAMYCIN; RENIN; TRIAMCINOLONE ACETONIDE; UNCLASSIFIED DRUG; VASCULOTROPIN; VEGF TRAP EYE;

EID: 84873091325     PISSN: 09405429     EISSN: 14325233     Source Type: Journal    
DOI: 10.1007/s00592-012-0449-3     Document Type: Review
Times cited : (131)

References (217)
  • 1
    • 58149269716 scopus 로고    scopus 로고
    • Projection of diabetic retinopathy and other major eye diseases among people with diabetes mellitus: United States, 2005-2050
    • Saddine JB, Honeycutt AA, Narayan KM et al (2008) Projection of diabetic retinopathy and other major eye diseases among people with diabetes mellitus: United States, 2005-2050. Arch Ophtahlmol 126:1740-1747
    • (2008) Arch Ophtahlmol , vol.126 , pp. 1740-1747
    • Saddine, J.B.1    Honeycutt, A.A.2    Narayan, K.M.3
  • 2
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • Diabetes Control and Complications Trial Research Group
    • Diabetes Control and Complications Trial Research Group (1993) The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329:977-986
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 3
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes. UKPDS 33
    • UK Prospective Diabetes Study Group
    • UK Prospective Diabetes Study Group (1998) Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes. UKPDS 33. Lancet 352:837-853
    • (1998) Lancet , vol.352 , pp. 837-853
  • 6
    • 42049118293 scopus 로고    scopus 로고
    • Clinical review: The role of advanced glycation end products in progression and complications of diabetes
    • 18182449 1:CAS:528:DC%2BD1cXks1ahtb0%3D
    • Goh SY, Cooper ME (2008) Clinical review: the role of advanced glycation end products in progression and complications of diabetes. J Clin Endocrinol Metab 93:1143-1152
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 1143-1152
    • Goh, S.Y.1    Cooper, M.E.2
  • 7
    • 84884901449 scopus 로고    scopus 로고
    • Retinal heat shock protein 25 in early experimental diabetes
    • epub ahead of print
    • Pinach S, Burt D, Berrone E et al (2011) Retinal heat shock protein 25 in early experimental diabetes. Acta Diabetol (epub ahead of print)
    • (2011) Acta Diabetol
    • Pinach, S.1    Burt, D.2    Berrone, E.3
  • 8
    • 78650694109 scopus 로고    scopus 로고
    • Pentosidine and N-carboxymethyl-lysine: Biomarkers for type 2 diabetic retinopathy
    • Ghanem AA, Elewa A, Arafa LF (2011) Pentosidine and N-carboxymethyl- lysine: biomarkers for type 2 diabetic retinopathy. Eur J Ophtahlmol 21:48-54
    • (2011) Eur J Ophtahlmol , vol.21 , pp. 48-54
    • Ghanem, A.A.1    Elewa, A.2    Arafa, L.F.3
  • 9
    • 80051599575 scopus 로고    scopus 로고
    • AGEs, RAGE, and diabetic retinopathy
    • Zong H, Ward M, Stitt AW (2011) AGEs, RAGE, and diabetic retinopathy. Curr DiabRep 11:244-252
    • (2011) Curr DiabRep , vol.11 , pp. 244-252
    • Zong, H.1    Ward, M.2    Stitt, A.W.3
  • 10
    • 21544463410 scopus 로고    scopus 로고
    • Aldose reductase in diabetic microvascular complications
    • 16026266 1:CAS:528:DC%2BD2MXlslChtb8%3D
    • Chung SS, Chung SK (2005) Aldose reductase in diabetic microvascular complications. Curr Drug Targets 6:475-486
    • (2005) Curr Drug Targets , vol.6 , pp. 475-486
    • Chung, S.S.1    Chung, S.K.2
  • 11
    • 34547935418 scopus 로고    scopus 로고
    • The polyol pathway as a mechanism for diabetic retinopathy: Attractive, elusive, and resilient
    • 18224243
    • Lorenzi M (2007) The polyol pathway as a mechanism for diabetic retinopathy: attractive, elusive, and resilient. Exp Diabetes Res 2007:61038
    • (2007) Exp Diabetes Res , vol.2007 , pp. 61038
    • Lorenzi, M.1
  • 12
    • 77952468064 scopus 로고    scopus 로고
    • Activation of protein kinase C isoforms and its impact on diabetic complications
    • 20431074 1:CAS:528:DC%2BC3cXmtlaktLc%3D
    • Geraldes P, King GL (2010) Activation of protein kinase C isoforms and its impact on diabetic complications. Circ Res 106:1319-1331
    • (2010) Circ Res , vol.106 , pp. 1319-1331
    • Geraldes, P.1    King, G.L.2
  • 13
    • 68349102012 scopus 로고    scopus 로고
    • Homocysteine levels in the vitreous of proliferative diabetic retinopathy and rhegmatogenous retinal detachment: Its modulating role on lysyl oxidase
    • 19369240
    • Coral K, Angayarkanni N, Gomathy N et al (2009) Homocysteine levels in the vitreous of proliferative diabetic retinopathy and rhegmatogenous retinal detachment: its modulating role on lysyl oxidase. Invest Ophthalmol Vis Sci 50:3607-3612
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 3607-3612
    • Coral, K.1    Angayarkanni, N.2    Gomathy, N.3
  • 14
    • 54949157448 scopus 로고    scopus 로고
    • Oxidative stress and diabetic retinopathy: Pathophysiological mechanisms and treatment perspectives
    • 18654858 1:CAS:528:DC%2BD1cXht1yrurrN
    • Madsen-Bouterse SA, Kowluru RA (2008) Oxidative stress and diabetic retinopathy: pathophysiological mechanisms and treatment perspectives. Rev Endocr Metab Disord 9:315-327
    • (2008) Rev Endocr Metab Disord , vol.9 , pp. 315-327
    • Madsen-Bouterse, S.A.1    Kowluru, R.A.2
  • 15
    • 42449135678 scopus 로고    scopus 로고
    • Immunological mechanisms in the pathogenesis of diabetic retinopathy
    • 18340447 1:CAS:528:DC%2BD1cXkslKiu78%3D
    • Adamis AP, Berman AJ (2008) Immunological mechanisms in the pathogenesis of diabetic retinopathy. Semin Immunopathol 30:65-84
    • (2008) Semin Immunopathol , vol.30 , pp. 65-84
    • Adamis, A.P.1    Berman, A.J.2
  • 16
    • 84879211917 scopus 로고    scopus 로고
    • Expression of lysophosphatidic acid, autotaxin and acylglycerol kinase as biomarkers in diabetic retinopathy
    • epub ahead of print
    • Abu El-Asrar AM, Mohammad G, Nawaz MI et al (2012) Expression of lysophosphatidic acid, autotaxin and acylglycerol kinase as biomarkers in diabetic retinopathy. Acta Diabetol (epub ahead of print)
    • (2012) Acta Diabetol
    • Abu El-Asrar, A.M.1    Mohammad, G.2    Nawaz, M.I.3
  • 17
    • 70350539302 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-A: A multifunctional molecular player in diabetic retinopathy
    • 19646547 1:CAS:528:DC%2BD1MXhtlGhsrzL
    • Zhang X, Bao S, Hambly BD, Gillies MC (2009) Vascular endothelial growth factor-A: a multifunctional molecular player in diabetic retinopathy. Int J Biochem Cell Biol 41:2368-2371
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 2368-2371
    • Zhang, X.1    Bao, S.2    Hambly, B.D.3    Gillies, M.C.4
  • 18
    • 15644366961 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta isoform selective inhibitor
    • 9287049 1:CAS:528:DyaK2sXlvFenu7o%3D
    • Aiello LP, Bursell S-E, Clermont A et al (1997) Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta isoform selective inhibitor. Diabetes 46:1473-1480
    • (1997) Diabetes , vol.46 , pp. 1473-1480
    • Aiello, L.P.1    Bursell, S.-E.2    Clermont, A.3
  • 19
    • 0033551811 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces rapid phosphorylation of tight junction proteins occludin and zonula occluden 1
    • 10438525 1:CAS:528:DyaK1MXltlKnu70%3D
    • Antonetti DA, Barber AJ, Hollinger LA et al (1999) Vascular endothelial growth factor induces rapid phosphorylation of tight junction proteins occludin and zonula occluden 1. J Biol Chem 274:23463-23467
    • (1999) J Biol Chem , vol.274 , pp. 23463-23467
    • Antonetti, D.A.1    Barber, A.J.2    Hollinger, L.A.3
  • 20
    • 0027942607 scopus 로고
    • Vascular endothelial growth factor in ocular fluids of patients with diabetic retinopathy and other retinal disorders
    • 7526212 1:STN:280:DyaK2M%2FlvFamsA%3D%3D
    • Aiello LP, Avery RL, Arrigg PG et al (1994) Vascular endothelial growth factor in ocular fluids of patients with diabetic retinopathy and other retinal disorders. N Engl J Med 331:1480-1487
    • (1994) N Engl J Med , vol.331 , pp. 1480-1487
    • Aiello, L.P.1    Avery, R.L.2    Arrigg, P.G.3
  • 21
    • 0028826101 scopus 로고
    • Hypoxic regulation of vascular endothelial growth factor in retinal cells
    • Aiello LP, Northrup JM, Keyt BA et al (1995) Hypoxic regulation of vascular endothelial growth factor in retinal cells. Arch Ophthalmol 1131:1538-1544
    • (1995) Arch Ophthalmol , vol.1131 , pp. 1538-1544
    • Aiello, L.P.1    Northrup, J.M.2    Keyt, B.A.3
  • 22
    • 0036207489 scopus 로고    scopus 로고
    • Angiotensin II and vascular endothelial growth factor in the vitreous fluid of patients with diabetic macular edema and other retinal disorders
    • 11931788 1:CAS:528:DC%2BD38XisV2rtLg%3D
    • Funatsu H, Yamashita H, Ikeda T et al (2002) Angiotensin II and vascular endothelial growth factor in the vitreous fluid of patients with diabetic macular edema and other retinal disorders. Am J Ophthalmol 133:537-543
    • (2002) Am J Ophthalmol , vol.133 , pp. 537-543
    • Funatsu, H.1    Yamashita, H.2    Ikeda, T.3
  • 23
    • 84864934564 scopus 로고    scopus 로고
    • Angiotensin-(1-7) suppresses oxidative stress and improves glucose uptake via Mas receptor in adipocytes
    • 22042130 1:CAS:528:DC%2BC38XhtFaks7nP
    • Liu C, Lv XH, Li HX et al (2012) Angiotensin-(1-7) suppresses oxidative stress and improves glucose uptake via Mas receptor in adipocytes. Acta Diabetol 49:291-299
    • (2012) Acta Diabetol , vol.49 , pp. 291-299
    • Liu, C.1    Lv, X.H.2    Li, H.X.3
  • 24
    • 84887437392 scopus 로고    scopus 로고
    • Insulin-induced hypoglycemia and stress oxidative state in healthy people
    • epub ahead of print
    • Yousefzade G, Nakhaee A (2011) Insulin-induced hypoglycemia and stress oxidative state in healthy people. Acta Diabetol (epub ahead of print)
    • (2011) Acta Diabetol
    • Yousefzade, G.1    Nakhaee, A.2
  • 25
    • 0033753370 scopus 로고    scopus 로고
    • Angiotensin converting enzyme inhibition reduces retinal overexpression of vascular endothelial growth factor and hypermeability in experimental diabetes
    • 11126403 1:CAS:528:DC%2BD3cXnsFWiu7g%3D
    • Gilbert RE, Kelly DJ, Cox AJ et al (2000) Angiotensin converting enzyme inhibition reduces retinal overexpression of vascular endothelial growth factor and hypermeability in experimental diabetes. Diabetologia 43:1360-1367
    • (2000) Diabetologia , vol.43 , pp. 1360-1367
    • Gilbert, R.E.1    Kelly, D.J.2    Cox, A.J.3
  • 26
    • 84859012407 scopus 로고    scopus 로고
    • Diabetic retinopathy. Mechanisms of disease
    • 22455417 1:CAS:528:DC%2BC38XlsVClu7Y%3D
    • Antonetti D, Klein R, Gardner T (2012) Diabetic retinopathy. Mechanisms of disease. N Engl J Med 366:1227-1239
    • (2012) N Engl J Med , vol.366 , pp. 1227-1239
    • Antonetti, D.1    Klein, R.2    Gardner, T.3
  • 27
    • 4344691457 scopus 로고    scopus 로고
    • Local multifocal oscillatory potential abnormalities in diabetes and early diabetic retinopathy
    • 15326149
    • Bearse M, Han Y, Schneck M et al (2004) Local multifocal oscillatory potential abnormalities in diabetes and early diabetic retinopathy. Invest Ophthalmol Vis Sci 45:3259-3265
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 3259-3265
    • Bearse, M.1    Han, Y.2    Schneck, M.3
  • 28
    • 10044280359 scopus 로고    scopus 로고
    • Multifocal electroretinogram and short-wavelenght automated perimetry measures in diabetic eyes with little or no retinopathy
    • 15596584
    • Han Y, Adams A, Bearse M et al (2004) Multifocal electroretinogram and short-wavelenght automated perimetry measures in diabetic eyes with little or no retinopathy. Arch Ophthalmol 122:1809-1815
    • (2004) Arch Ophthalmol , vol.122 , pp. 1809-1815
    • Han, Y.1    Adams, A.2    Bearse, M.3
  • 29
    • 33747012605 scopus 로고    scopus 로고
    • Glutamate-induced apoptosis in neuronal cells is mediated via caspase-dependent and independent mechanisms involving calpain and caspase-3 proteases as well as apoptosis inducing factor (AIF) and this process is inhibited by equine estrogens
    • 16776830
    • Zhang Y, Bhavnani BR (2006) Glutamate-induced apoptosis in neuronal cells is mediated via caspase-dependent and independent mechanisms involving calpain and caspase-3 proteases as well as apoptosis inducing factor (AIF) and this process is inhibited by equine estrogens. BMC Neurosci 7:49
    • (2006) BMC Neurosci , vol.7 , pp. 49
    • Zhang, Y.1    Bhavnani, B.R.2
  • 30
    • 84862737626 scopus 로고    scopus 로고
    • The potential role of glutamate in the current diabetes epidemic
    • 22218826 1:CAS:528:DC%2BC38XotVSjtr0%3D
    • Davalli AM, Perego C, Folli FB (2012) The potential role of glutamate in the current diabetes epidemic. Acta Diabetol 49:167-183
    • (2012) Acta Diabetol , vol.49 , pp. 167-183
    • Davalli, A.M.1    Perego, C.2    Folli, F.B.3
  • 31
    • 33751520614 scopus 로고    scopus 로고
    • Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy
    • The PKC-DRS2 Group
    • The PKC-DRS2 Group (2006) Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy. Ophthalmology 113:2221-2230
    • (2006) Ophthalmology , vol.113 , pp. 2221-2230
  • 32
    • 54049107380 scopus 로고    scopus 로고
    • Diabetes downregulates presynaptic proteins and reduced basal synapsin 1 phosphorylation in rat retina
    • 18662330
    • VanGuilder HD, Brucklacher AR, Patel K et al (2008) Diabetes downregulates presynaptic proteins and reduced basal synapsin 1 phosphorylation in rat retina. Eur J Neurosci 28:1-11
    • (2008) Eur J Neurosci , vol.28 , pp. 1-11
    • Vanguilder, H.D.1    Brucklacher, A.R.2    Patel, K.3
  • 33
    • 4344599833 scopus 로고    scopus 로고
    • Involvement of brain-derived neurotrophic factor in early retinal neuropathy of streptozotocin-induced diabetes in rats: Therapeutic potential of brain-derived neurotrophic factor for dopaminergic amacrine cells
    • 15331553 1:CAS:528:DC%2BD2cXns1ShsLw%3D
    • Seki M, Tanaka T, Nawa H et al (2004) Involvement of brain-derived neurotrophic factor in early retinal neuropathy of streptozotocin-induced diabetes in rats: therapeutic potential of brain-derived neurotrophic factor for dopaminergic amacrine cells. Diabetes 53:2412-2419
    • (2004) Diabetes , vol.53 , pp. 2412-2419
    • Seki, M.1    Tanaka, T.2    Nawa, H.3
  • 34
    • 0023766804 scopus 로고
    • Retinal pigment epithelial cells in culture produce retinal vascular mitogens
    • 2460072 1:STN:280:DyaL1M%2FisFarsQ%3D%3D
    • Wong HC, Boulton M, McLeod D et al (1988) Retinal pigment epithelial cells in culture produce retinal vascular mitogens. Arch Ophthalmol 106:1439-1443
    • (1988) Arch Ophthalmol , vol.106 , pp. 1439-1443
    • Wong, H.C.1    Boulton, M.2    McLeod, D.3
  • 35
    • 77956380383 scopus 로고    scopus 로고
    • Müller cell-derived VEGF is essential for diabetes-induced retinal inflammation and vascular leakage
    • 20530741 1:CAS:528:DC%2BC3cXht12ku77N
    • Wang J, Xu X, Elliott MH et al (2010) Müller cell-derived VEGF is essential for diabetes-induced retinal inflammation and vascular leakage. Diabetes 59:2297-2305
    • (2010) Diabetes , vol.59 , pp. 2297-2305
    • Wang, J.1    Xu, X.2    Elliott, M.H.3
  • 36
    • 68949129005 scopus 로고    scopus 로고
    • Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor-induced permeability
    • 19478092 1:CAS:528:DC%2BD1MXovFWrtbY%3D
    • Murakami T, Felinski EA, Antonetti DA (2009) Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor-induced permeability. J Biol Chem 284:21036-21046
    • (2009) J Biol Chem , vol.284 , pp. 21036-21046
    • Murakami, T.1    Felinski, E.A.2    Antonetti, D.A.3
  • 37
    • 18544366585 scopus 로고    scopus 로고
    • Endothelium-specific platelet-derived growth factor-β ablation mimics diabetic retinopathy
    • 12169633 1:CAS:528:DC%2BD38Xms1KntLg%3D
    • Enge M, Bjarnegård M, Gerhardt H et al (2002) Endothelium-specific platelet-derived growth factor-β ablation mimics diabetic retinopathy. EMBO J 21:4307-4316
    • (2002) EMBO J , vol.21 , pp. 4307-4316
    • Enge, M.1    Bjarnegård, M.2    Gerhardt, H.3
  • 38
    • 84878893830 scopus 로고    scopus 로고
    • Human pericyte-endothelial cell interactions in co-culture models mimicking the diabetic retinal microvascular environment
    • epub ahead of print
    • Tarallo S, Beltramo E, Berrone E, Porta M (2012) Human pericyte-endothelial cell interactions in co-culture models mimicking the diabetic retinal microvascular environment. Acta Diabetol (epub ahead of print)
    • (2012) Acta Diabetol
    • Tarallo, S.1    Beltramo, E.2    Berrone, E.3    Porta, M.4
  • 39
    • 33846991924 scopus 로고    scopus 로고
    • Extracellular carbonic anhydrase mediates haemorrhagic retinal and cerebral vascular permeability through prekallikrein activation
    • 17259996 1:CAS:528:DC%2BD2sXhsVyktbg%3D
    • Gao BB, Clermont A, Rook S et al (2007) Extracellular carbonic anhydrase mediates haemorrhagic retinal and cerebral vascular permeability through prekallikrein activation. Nat Med 13:181-188
    • (2007) Nat Med , vol.13 , pp. 181-188
    • Gao, B.B.1    Clermont, A.2    Rook, S.3
  • 40
    • 84885424983 scopus 로고    scopus 로고
    • Effect of obesity and glycemic control on serum lipocalins and insulin-like growth factor axis in type 2 diabetic patients
    • epub ahead of print
    • El-Mesallamy HO, Hamdy NM, Sallam AA (2012) Effect of obesity and glycemic control on serum lipocalins and insulin-like growth factor axis in type 2 diabetic patients. Acta Diabetol (epub ahead of print)
    • (2012) Acta Diabetol
    • El-Mesallamy, H.O.1    Hamdy, N.M.2    Sallam, A.A.3
  • 41
    • 84875220403 scopus 로고    scopus 로고
    • Management of newly diagnosed patients with type 2 diabetes: What are the attitudes of physicians? A SUBITO!AMD survey on the early diabetes treatment in Italy
    • epub ahead of print
    • Suraci C, Mulas F, Rossi MC et al (2012) Management of newly diagnosed patients with type 2 diabetes: what are the attitudes of physicians? A SUBITO!AMD survey on the early diabetes treatment in Italy. Acta Diabetol (epub ahead of print)
    • (2012) Acta Diabetol
    • Suraci, C.1    Mulas, F.2    Rossi, M.C.3
  • 42
    • 84878894191 scopus 로고    scopus 로고
    • The importance of HbA1c and glucose variability in patients with type 1 and type 2 diabetes: Outcome of continuous glucose monitoring (CGM)
    • epub ahead of print
    • Sartore G, Chilelli NC, Burlina S et al (2012) The importance of HbA1c and glucose variability in patients with type 1 and type 2 diabetes: outcome of continuous glucose monitoring (CGM). Acta Diabetol (epub ahead of print)
    • (2012) Acta Diabetol
    • Sartore, G.1    Chilelli, N.C.2    Burlina, S.3
  • 43
    • 84864923640 scopus 로고    scopus 로고
    • Post-prandial glucose and diabetic complications: Systematic review of observational studies
    • 22116350 1:CAS:528:DC%2BC38XhtFaks7nE
    • Mannucci E, Monami M, Lamanna C, Adalsteinsson JE (2012) Post-prandial glucose and diabetic complications: systematic review of observational studies. Acta Diabetol 49:307-314
    • (2012) Acta Diabetol , vol.49 , pp. 307-314
    • Mannucci, E.1    Monami, M.2    Lamanna, C.3    Adalsteinsson, J.E.4
  • 44
    • 74949138626 scopus 로고    scopus 로고
    • The effects of baseline characteristics, glycaemia treatment approach, and glycated hemoglobin concentration on the risk of severe hypoglycaemia: Post hoc epidemiological analysis of the ACCORD study
    • for the ACCORD Investigators et al. 10.1136/bmj.b5444 20061360
    • Miller ME, Bonds DE, Gerstein HC, for the ACCORD Investigators et al (2010) The effects of baseline characteristics, glycaemia treatment approach, and glycated hemoglobin concentration on the risk of severe hypoglycaemia: post hoc epidemiological analysis of the ACCORD study. BMJ 340:b5444. doi: 10.1136/bmj.b5444
    • (2010) BMJ , vol.340 , pp. 5444
    • Miller, M.E.1    Bonds, D.E.2    Gerstein, H.C.3
  • 45
    • 0024456469 scopus 로고
    • Is blood pressure a predictor of the incidence or progression of diabetic retinopathy?
    • 2684072 1:STN:280:DyaK3c%2FlsFGgsw%3D%3D
    • Klein R, Klein BE, Moss SE et al (1989) Is blood pressure a predictor of the incidence or progression of diabetic retinopathy? Arch Intern Med 149:2427-2432
    • (1989) Arch Intern Med , vol.149 , pp. 2427-2432
    • Klein, R.1    Klein, B.E.2    Moss, S.E.3
  • 46
    • 0032511580 scopus 로고    scopus 로고
    • Tight blood pressure control and risk of microvascular complications in type 2 diabetes. UKPDS 38
    • UK Prospective Diabetes Study Group
    • UK Prospective Diabetes Study Group (1998) Tight blood pressure control and risk of microvascular complications in type 2 diabetes. UKPDS 38. BMJ 317:703-713
    • (1998) BMJ , vol.317 , pp. 703-713
  • 47
    • 79959330386 scopus 로고    scopus 로고
    • Effect on trandolapril on regression of retinopathy in hypertensive patients with type 2 diabetes: A prespecified analysis of the BENEDICT trial
    • 20628590
    • Ruggenenti P, Iliev I, Filipponi M et al (2010) Effect on trandolapril on regression of retinopathy in hypertensive patients with type 2 diabetes: a prespecified analysis of the BENEDICT trial. J Ophthalmol 2010:106384
    • (2010) J Ophthalmol , vol.2010 , pp. 106384
    • Ruggenenti, P.1    Iliev, I.2    Filipponi, M.3
  • 48
    • 0032477583 scopus 로고    scopus 로고
    • Effects of lisinopril on progression of retinopathy in normotensive people with type 1 diabetes. The EUCLID Study Group. EURODIAB Controlled Trial of Lisinopril in Insulin-Dependent Diabetes Mellitus
    • Chaturvedi N, Sjolie AK, Stephenson JM et al (1998) Effects of lisinopril on progression of retinopathy in normotensive people with type 1 diabetes. The EUCLID Study Group. EURODIAB Controlled Trial of Lisinopril in Insulin-Dependent Diabetes Mellitus. Lancet 351:28-31
    • (1998) Lancet , vol.351 , pp. 28-31
    • Chaturvedi, N.1    Sjolie, A.K.2    Stephenson, J.M.3
  • 49
    • 53749100124 scopus 로고    scopus 로고
    • Effects of candesartan on prevention (DIRECT-Prevent 1) and progression (DIRECT-Protect 1) of retinopathy in type 1 diabetes: Randomised, placebo-controlled trials
    • Chatuvedi N, Porta M, Klein R et al (2008) Effects of candesartan on prevention (DIRECT-Prevent 1) and progression (DIRECT-Protect 1) of retinopathy in type 1 diabetes: randomised, placebo-controlled trials. Lancet 372:1394-1402
    • (2008) Lancet , vol.372 , pp. 1394-1402
    • Chatuvedi, N.1    Porta, M.2    Klein, R.3
  • 50
    • 84878893936 scopus 로고    scopus 로고
    • Insulin resistance is associated with elevated serum pigment epithelium-derived factor (PEDF) levels in morbidly obese patients
    • epub ahead of print
    • Gattu AK, Birkenfeld AL, Jornayvaz F et al (2012) Insulin resistance is associated with elevated serum pigment epithelium-derived factor (PEDF) levels in morbidly obese patients. Acta Diabetol (epub ahead of print)
    • (2012) Acta Diabetol
    • Gattu, A.K.1    Birkenfeld, A.L.2    Jornayvaz, F.3
  • 51
    • 84873086774 scopus 로고    scopus 로고
    • Lipid accumulation in overweight type 2 diabetic subjects: Relationships with insulin sensitivity and adipokines
    • epub ahead of print
    • Sambataro M, Perseghin G, Lattuada G et al (2012) Lipid accumulation in overweight type 2 diabetic subjects: relationships with insulin sensitivity and adipokines. Acta Diabetol (epub ahead of print)
    • (2012) Acta Diabetol
    • Sambataro, M.1    Perseghin, G.2    Lattuada, G.3
  • 52
    • 36049001784 scopus 로고    scopus 로고
    • Effect of fenofibrate on the need for laser treatment for diabetic retinopathy (FIELD study): A randomised controlled trial
    • 17988728 1:CAS:528:DC%2BD2sXhtlWrsb7K
    • Keech AC, Mitchell P, Summanen PA et al (2007) Effect of fenofibrate on the need for laser treatment for diabetic retinopathy (FIELD study): a randomised controlled trial. Lancet 370:1687-1697
    • (2007) Lancet , vol.370 , pp. 1687-1697
    • Keech, A.C.1    Mitchell, P.2    Summanen, P.A.3
  • 53
    • 47349117843 scopus 로고    scopus 로고
    • Selective activation of peroxisome proliferator-activated receptor (PPAR) alpha and PPAR gamma induces neoangiogenesis through a vascular endothelial frowth factor-dependant mechanism
    • 18268046 1:CAS:528:DC%2BD1cXlvVKjur4%3D
    • Biscetti F, Gaetani E, Flex A et al (2008) Selective activation of peroxisome proliferator-activated receptor (PPAR) alpha and PPAR gamma induces neoangiogenesis through a vascular endothelial frowth factor-dependant mechanism. Diabetes 57:1394-1404
    • (2008) Diabetes , vol.57 , pp. 1394-1404
    • Biscetti, F.1    Gaetani, E.2    Flex, A.3
  • 54
    • 84879212891 scopus 로고    scopus 로고
    • Targeting educational therapy for type 2 diabetes: Identification of predictors of therapeutic success
    • epub ahead of print
    • da Vico L, Monami M, Biffi B et al (2012) Targeting educational therapy for type 2 diabetes: identification of predictors of therapeutic success. Acta Diabetol (epub ahead of print)
    • (2012) Acta Diabetol
    • Da Vico, L.1    Monami, M.2    Biffi, B.3
  • 55
    • 0022518460 scopus 로고
    • Diabetic macular edema: A review
    • Bresnik GH (1986) Diabetic macular edema: a review. Ophthalmology 93:989-997
    • (1986) Ophthalmology , vol.93 , pp. 989-997
    • Bresnik, G.H.1
  • 56
    • 67749084303 scopus 로고    scopus 로고
    • Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration
    • Diabetes Control and Complications Trial/Epidemiology of Diabetes Inteventions and Complications (DCCT/EDIC) Research Group
    • Diabetes Control and Complications Trial/Epidemiology of Diabetes Inteventions and Complications (DCCT/EDIC) Research Group (2009) Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration. Arch Int Med 169:1307-1316
    • (2009) Arch Int Med , vol.169 , pp. 1307-1316
  • 57
    • 77955376918 scopus 로고    scopus 로고
    • Prevalence of diabetic retinopathy in the United States, 2005-2008
    • 20699456 1:CAS:528:DC%2BC3cXhtVelsbvE
    • Zhang X, Saaddine JB, Chou CF et al (2010) Prevalence of diabetic retinopathy in the United States, 2005-2008. JAMA 304:649-656
    • (2010) JAMA , vol.304 , pp. 649-656
    • Zhang, X.1    Saaddine, J.B.2    Chou, C.F.3
  • 58
    • 72749093057 scopus 로고    scopus 로고
    • The 25-year incidence of visual impairment in type 1 diabets mellitus. The Wisconsin Epidemiologic Study of Diabetic Retinopathy
    • 19880184
    • Klein R, Lee KE, Gangnon RE et al (2010) The 25-year incidence of visual impairment in type 1 diabets mellitus. The Wisconsin Epidemiologic Study of Diabetic Retinopathy. Ophthalmology 117:63-70
    • (2010) Ophthalmology , vol.117 , pp. 63-70
    • Klein, R.1    Lee, K.E.2    Gangnon, R.E.3
  • 59
    • 70350566640 scopus 로고    scopus 로고
    • Blindness in a 25-year follow-up of a population-based cohort of Danish type 1 diabetic patients
    • 19744716
    • Grauslund J, Green A, Sjolie AK et al (2009) Blindness in a 25-year follow-up of a population-based cohort of Danish type 1 diabetic patients. Ophthalmology 116:2170-2174
    • (2009) Ophthalmology , vol.116 , pp. 2170-2174
    • Grauslund, J.1    Green, A.2    Sjolie, A.K.3
  • 60
    • 77953555650 scopus 로고    scopus 로고
    • Burden of ilness of diabetic macular edema: Literature review
    • 20429823 1:CAS:528:DC%2BC3cXnsVyitbg%3D
    • Chen E, Looman M, Laouri M et al (2010) Burden of ilness of diabetic macular edema: literature review. Curr Med Res Opin 26:1587-1597
    • (2010) Curr Med Res Opin , vol.26 , pp. 1587-1597
    • Chen, E.1    Looman, M.2    Laouri, M.3
  • 61
    • 0030034714 scopus 로고    scopus 로고
    • Cost-effectiveness of detecting and treating diabetic retinopathy
    • 8554212 1:STN:280:DyaK287kslagug%3D%3D
    • Javitt JC, Aiello LP (1996) Cost-effectiveness of detecting and treating diabetic retinopathy. Ann Intern Med 124:164-169
    • (1996) Ann Intern Med , vol.124 , pp. 164-169
    • Javitt, J.C.1    Aiello, L.P.2
  • 63
    • 77955810119 scopus 로고    scopus 로고
    • Steroids as part of combination treatment: The future for the management of macular edema?
    • 20714180 1:CAS:528:DC%2BC3cXhtVaqtL3F
    • Bandello F, Battaglia Parodi M, Tremolada G et al (2010) Steroids as part of combination treatment: the future for the management of macular edema? Ophthalmologica 224(Suppl 1):41-45
    • (2010) Ophthalmologica , vol.224 , Issue.SUPPL. 1 , pp. 41-45
    • Bandello, F.1    Battaglia Parodi, M.2    Tremolada, G.3
  • 64
    • 0003573130 scopus 로고
    • Photocoagulation for diabetic macular edema: ETDRS report number 4
    • Early Treatment Diabetic Retinopathy Study Research Group
    • Early Treatment Diabetic Retinopathy Study Research Group (1987) Photocoagulation for diabetic macular edema: ETDRS report number 4. Int Ophthalmol Clin 27:265-272
    • (1987) Int Ophthalmol Clin , vol.27 , pp. 265-272
  • 65
    • 0022347471 scopus 로고
    • Photocoagulation for diabetic macular edema: Early Treatment Diabetic Retinopathy Study report number 1
    • Early Treatment Diabetic Retinopathy Study Research Group
    • Early Treatment Diabetic Retinopathy Study Research Group (1985) Photocoagulation for diabetic macular edema: Early Treatment Diabetic Retinopathy Study report number 1. Arch Ophthalmol 103:1796-1806
    • (1985) Arch Ophthalmol , vol.103 , pp. 1796-1806
  • 66
    • 0026075103 scopus 로고
    • Progressive enlargement of laser scars following grid laser photocoagulation for diffuse diabetic macular edema
    • 1755735 1:STN:280:DyaK38%2FpsFygtw%3D%3D
    • Schatz H, Madeira D, McDonald HR, Johnson RN (1991) Progressive enlargement of laser scars following grid laser photocoagulation for diffuse diabetic macular edema. Arch Ophthalmol 109:1549-5151
    • (1991) Arch Ophthalmol , vol.109 , pp. 1549-5151
    • Schatz, H.1    Madeira, D.2    McDonald, H.R.3    Johnson, R.N.4
  • 67
    • 78649361236 scopus 로고    scopus 로고
    • Short-duration focal pattern grid macular photocoagulation for diabetic macular edema: Four-month outcomes
    • 21060272
    • Jain A, Collen J, Kaines A et al (2010) Short-duration focal pattern grid macular photocoagulation for diabetic macular edema: four-month outcomes. Retina 30:1622-1626
    • (2010) Retina , vol.30 , pp. 1622-1626
    • Jain, A.1    Collen, J.2    Kaines, A.3
  • 68
    • 0023202345 scopus 로고
    • Treatment techniques and clinical guidelines for photocoagulation of diabetic macular edema. Early Treatment Diabetic Retinopathy Study report number 2
    • Early Treatment Diabetic Retinopathy Study Research Group
    • Early Treatment Diabetic Retinopathy Study Research Group (1987) Treatment techniques and clinical guidelines for photocoagulation of diabetic macular edema. Early Treatment Diabetic Retinopathy Study report number 2. Ophthalmology 94:761-774
    • (1987) Ophthalmology , vol.94 , pp. 761-774
  • 69
    • 6844253748 scopus 로고
    • Focal versus scattered argon-green in diffuse macular edema: A prospective randomized trial
    • Gitter KA, Schatz H, Yannuzzi LA, Mc Donald HR (eds) San Francisco Pacific Medical Press
    • Brancato R, Menchini U, Scialdone A, Bandello F (1988) Focal versus scattered argon-green in diffuse macular edema: a prospective randomized trial. In: Gitter KA, Schatz H, Yannuzzi LA, Mc Donald HR (eds) Laser photocoagulation of retinal disease. San Francisco Pacific Medical Press, pp 69-73
    • (1988) Laser Photocoagulation of Retinal Disease , pp. 69-73
    • Brancato, R.1    Menchini, U.2    Scialdone, A.3    Bandello, F.4
  • 70
    • 34247164981 scopus 로고    scopus 로고
    • Comparison of the modified early treatment diabetic retinopathy study and mild macular grid laser photocoagulation strategies for diabetic macular edema
    • Writing Committee for the Diabetic Retinopathy Clinical Research Network
    • Writing Committee for the Diabetic Retinopathy Clinical Research Network (2007) Comparison of the modified early treatment diabetic retinopathy study and mild macular grid laser photocoagulation strategies for diabetic macular edema. Arch Ophthalmol 125:469-480
    • (2007) Arch Ophthalmol , vol.125 , pp. 469-480
  • 71
    • 21344454186 scopus 로고    scopus 로고
    • 'Light' versus 'classic' laser treatment for clinically significant diabetic macular oedema
    • 15965168 1:STN:280:DC%2BD2MzhsFakug%3D%3D
    • Bandello F, Polito A, Borrello MD et al (2005) 'Light' versus 'classic' laser treatment for clinically significant diabetic macular oedema. Br J Ophthalmol 89:864-870
    • (2005) Br J Ophthalmol , vol.89 , pp. 864-870
    • Bandello, F.1    Polito, A.2    Borrello, M.D.3
  • 72
    • 33744801932 scopus 로고    scopus 로고
    • Micropulse and continuous wave diode retinal photocoagulation: Visible and subvisible lesion parameters
    • 16531424 1:STN:280:DC%2BD283ot1Okuw%3D%3D
    • Desmettre TJ, Mordon SR, Buzawa DM et al (2006) Micropulse and continuous wave diode retinal photocoagulation: visible and subvisible lesion parameters. Br J Ophthalmol 90:709-712
    • (2006) Br J Ophthalmol , vol.90 , pp. 709-712
    • Desmettre, T.J.1    Mordon, S.R.2    Buzawa, D.M.3
  • 73
    • 77953344075 scopus 로고    scopus 로고
    • Microperimetry and fundus autofluorescence in diabetic macular edema: Subthreshold micropulse diode laser versus modified early treatment diabetic retinopathy study laser photocoagulation
    • 20168272
    • Vujosevic S, Bottega E, Casciano M et al (2010) Microperimetry and fundus autofluorescence in diabetic macular edema: subthreshold micropulse diode laser versus modified early treatment diabetic retinopathy study laser photocoagulation. Retina 30:908-916
    • (2010) Retina , vol.30 , pp. 908-916
    • Vujosevic, S.1    Bottega, E.2    Casciano, M.3
  • 74
    • 77956576316 scopus 로고    scopus 로고
    • Functional outcome of subthreshold versus threshold diode laser photocoagulation in diabetic macular oedema
    • 20431612 1:STN:280:DC%2BC3cfgslSmug%3D%3D
    • Kumar V, Ghosh B, Mehta DK, Goel N (2010) Functional outcome of subthreshold versus threshold diode laser photocoagulation in diabetic macular oedema. Eye 24:1459-1465
    • (2010) Eye , vol.24 , pp. 1459-1465
    • Kumar, V.1    Ghosh, B.2    Mehta, D.K.3    Goel, N.4
  • 75
    • 70349973297 scopus 로고    scopus 로고
    • Prospective randomized controlled trial comparing subthreshold micropulse diode laser photocoagulation and conventional green laser for clinically significant diabetic macular oedema
    • 19054831
    • Figueira J, Khan J, Nunes S et al (2008) Prospective randomized controlled trial comparing subthreshold micropulse diode laser photocoagulation and conventional green laser for clinically significant diabetic macular oedema. Br J Ophthalmol 93:1341-1344
    • (2008) Br J Ophthalmol , vol.93 , pp. 1341-1344
    • Figueira, J.1    Khan, J.2    Nunes, S.3
  • 76
    • 80051655542 scopus 로고    scopus 로고
    • Randomized clinical trial evaluating mETDRS versus normal or high-density micropulse photocoagulation for diabetic macular edema
    • 21345996
    • Lavinsky D, Cardillo JA, Melo LAS et al (2011) Randomized clinical trial evaluating mETDRS versus normal or high-density micropulse photocoagulation for diabetic macular edema. Invest Ophthalmol Vis Sci 52:4314-4323
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 4314-4323
    • Lavinsky, D.1    Cardillo, J.A.2    Melo, L.A.S.3
  • 77
    • 84873084043 scopus 로고    scopus 로고
    • 577 nm MicroPulse laser therapy: Addressing the immediate need of our patients with DME
    • Cardillo JA (2012) 577 nm MicroPulse laser therapy: addressing the immediate need of our patients with DME. In: Retina Today, vol 7, pp 11-14
    • (2012) Retina Today , vol.7 , pp. 11-14
    • Cardillo, J.A.1
  • 78
    • 79551549641 scopus 로고    scopus 로고
    • Selective retinal therapy with microsecond exposures using a continuous line scanning laser
    • 20930656
    • Paulus YM, Jain A, Nomoto H et al (2011) Selective retinal therapy with microsecond exposures using a continuous line scanning laser. Retina 31:380-388
    • (2011) Retina , vol.31 , pp. 380-388
    • Paulus, Y.M.1    Jain, A.2    Nomoto, H.3
  • 79
    • 33646462793 scopus 로고    scopus 로고
    • Semiautomated patterned scanning laser for retinal photocoagulation
    • 16508446
    • Blumenkranz MS, Yellachich D, Andersen DE et al (2006) Semiautomated patterned scanning laser for retinal photocoagulation. Retina 26:370-376
    • (2006) Retina , vol.26 , pp. 370-376
    • Blumenkranz, M.S.1    Yellachich, D.2    Andersen, D.E.3
  • 81
    • 78149491541 scopus 로고    scopus 로고
    • Pain responses of Pascal 20 ms multi-spot and 100 ms single-spot panretinal photocoagulation: Manchester Pascal Study, MAPASS report 2
    • 20558423 1:STN:280:DC%2BC3cbgslKqtQ%3D%3D
    • Muqit MM, Marcellino GR, Gray JC et al (2010) Pain responses of Pascal 20 ms multi-spot and 100 ms single-spot panretinal photocoagulation: Manchester Pascal Study, MAPASS report 2. Br J Ophthalmol 94:1493-1498
    • (2010) Br J Ophthalmol , vol.94 , pp. 1493-1498
    • Muqit, M.M.1    Marcellino, G.R.2    Gray, J.C.3
  • 82
    • 77949415646 scopus 로고    scopus 로고
    • Comparison of laser photocoagulation for diabetic retinopathy using 532-nm standard laser versus multispot pattern scan laser
    • 20216293
    • Nagpal M, Marlecha S, Nagpal K (2010) Comparison of laser photocoagulation for diabetic retinopathy using 532-nm standard laser versus multispot pattern scan laser. Retina 30:452-458
    • (2010) Retina , vol.30 , pp. 452-458
    • Nagpal, M.1    Marlecha, S.2    Nagpal, K.3
  • 83
    • 79952413340 scopus 로고    scopus 로고
    • ® photocoagulator: An analysis of over 1,200 laser procedures with regard to parameter refinement
    • 21350276
    • ® photocoagulator: an analysis of over 1,200 laser procedures with regard to parameter refinement. Indian J Ophthalmol 59:87-91
    • (2011) Indian J Ophthalmol , vol.59 , pp. 87-91
    • Sheth, S.1    Lanzetta, P.2    Veritti, D.3
  • 84
    • 84865766287 scopus 로고    scopus 로고
    • Spectral-domain optical coherence tomography imaging of retinal changes after conventional multicolor laser, subthreshold micropulse diode laser, or pattern scanning laser therapy in Japanese with macular edema
    • 22466485
    • Inagaki K, Ohkoshi K, Ohde S (2012) Spectral-domain optical coherence tomography imaging of retinal changes after conventional multicolor laser, subthreshold micropulse diode laser, or pattern scanning laser therapy in Japanese with macular edema. Retina 32:1592-1600
    • (2012) Retina , vol.32 , pp. 1592-1600
    • Inagaki, K.1    Ohkoshi, K.2    Ohde, S.3
  • 85
    • 79958016997 scopus 로고    scopus 로고
    • Clinical evaluation and treatment accuracy in diabetic macular edema using navigated laser photocoagulator NAVILAS
    • 21269701
    • Kozak I, Oster SF, Cortes MA et al (2011) Clinical evaluation and treatment accuracy in diabetic macular edema using navigated laser photocoagulator NAVILAS. Ophthalmology 118:1119-1124
    • (2011) Ophthalmology , vol.118 , pp. 1119-1124
    • Kozak, I.1    Oster, S.F.2    Cortes, M.A.3
  • 86
    • 84857778924 scopus 로고    scopus 로고
    • Pain and accuracy of focal laser treatment for diabetic macular edema using a retinal navigated laser (Navilas)
    • 22393280
    • Kernt M, Cheuteu RE, Cserhati S et al (2012) Pain and accuracy of focal laser treatment for diabetic macular edema using a retinal navigated laser (Navilas). Clin Ophthalmol 6:289-296
    • (2012) Clin Ophthalmol , vol.6 , pp. 289-296
    • Kernt, M.1    Cheuteu, R.E.2    Cserhati, S.3
  • 88
    • 0017912754 scopus 로고
    • Photocoagulation of proliferative diabetic retinopathy study findings
    • Diabetic Retinopathy Group
    • Diabetic Retinopathy Group (1978) Photocoagulation of proliferative diabetic retinopathy study findings. Ophthalmology 85:82-105
    • (1978) Ophthalmology , vol.85 , pp. 82-105
  • 89
    • 0017233461 scopus 로고
    • Preliminary report on effects of photocoagulation therapy
    • Diabetic Retinopathy Study Research Group
    • Diabetic Retinopathy Study Research Group (1976) Preliminary report on effects of photocoagulation therapy. Am J Ophthalmol 1976:383-396
    • (1976) Am J Ophthalmol , vol.1976 , pp. 383-396
  • 90
    • 0025892104 scopus 로고
    • Early photocoagulation for diabetic retinopathy: ETDRS report number 9
    • Early Treatment Diabetic Retinopathy Study Research Group
    • Early Treatment Diabetic Retinopathy Study Research Group (1991) Early photocoagulation for diabetic retinopathy: ETDRS report number 9. Ophthalmology 98:S766-S785
    • (1991) Ophthalmology , vol.98
  • 91
    • 38349073488 scopus 로고    scopus 로고
    • Effect of pulse duration on size and character of the lesion in retinal photocfoagulation
    • 18195222
    • Jain A, Blumenkranz MS, Paulus Y et al (2008) Effect of pulse duration on size and character of the lesion in retinal photocfoagulation. Arch Ophthalmol 126:78-85
    • (2008) Arch Ophthalmol , vol.126 , pp. 78-85
    • Jain, A.1    Blumenkranz, M.S.2    Paulus, Y.3
  • 92
    • 49049106746 scopus 로고    scopus 로고
    • ® Photocoagulator: A pilot study of 75 procedures
    • 18586905 1:STN:280:DC%2BD1cvntlKntg%3D%3D
    • ® Photocoagulator: a pilot study of 75 procedures. Br J Ophthalmol 92:1061-1064
    • (2008) Br J Ophthalmol , vol.92 , pp. 1061-1064
    • Sanghvi, C.1    Mc Lauchlan, R.2    Delgado, C.3
  • 94
    • 60549112067 scopus 로고    scopus 로고
    • Observational study of the development of diabetic macula edema following panretinal (scatter) photocoagulation (PRP) given in 1 or 4 sittings
    • DRCR Network
    • DRCR Network (2009) Observational study of the development of diabetic macula edema following panretinal (scatter) photocoagulation (PRP) given in 1 or 4 sittings. Arch Ophthalmol 127:132-140
    • (2009) Arch Ophthalmol , vol.127 , pp. 132-140
  • 97
    • 74249085606 scopus 로고    scopus 로고
    • Recent advances in drug delivery systems for treating ocular complications of systemic diseases
    • 19667987
    • Lee SS, Hughes PM, Robinson MR (2009) Recent advances in drug delivery systems for treating ocular complications of systemic diseases. Curr Opin Ophthalmol 20:511-519
    • (2009) Curr Opin Ophthalmol , vol.20 , pp. 511-519
    • Lee, S.S.1    Hughes, P.M.2    Robinson, M.R.3
  • 98
    • 0031110584 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor by platelet-activating factor and platelet-derived growth factor is down-regulated by corticosteroids
    • Nauck M, Roth M, Tamm M et al (1998) Induction of vascular endothelial growth factor by platelet-activating factor and platelet-derived growth factor is down-regulated by corticosteroids. Am J Respir Cell Mol Biol 16:398-406
    • (1998) Am J Respir Cell Mol Biol , vol.16 , pp. 398-406
    • Nauck, M.1    Roth, M.2    Tamm, M.3
  • 99
    • 18244391221 scopus 로고    scopus 로고
    • Intravitreal injection of corticosteroid attenuates leukostasis and vascular leakage in experimental diabetic retina
    • 15790913
    • Tamura H, Miyamoto K, Kiryu J et al (2005) Intravitreal injection of corticosteroid attenuates leukostasis and vascular leakage in experimental diabetic retina. Invest Ophthalmol Vis Sci 46:1440-1444
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 1440-1444
    • Tamura, H.1    Miyamoto, K.2    Kiryu, J.3
  • 100
    • 77952882990 scopus 로고    scopus 로고
    • Randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with macular edema due to retinal vein occlusion
    • OZURDEX GENEVA Study Group et al. 20417567
    • Haller JA, Bandello F, Belfort R Jr, OZURDEX GENEVA Study Group et al (2010) Randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with macular edema due to retinal vein occlusion. Ophthalmology 117:1134-1146
    • (2010) Ophthalmology , vol.117 , pp. 1134-1146
    • Haller, J.A.1    Bandello, F.2    Belfort, Jr.R.3
  • 101
    • 0031737671 scopus 로고    scopus 로고
    • Vascular permeability in experimental diabetes is associated with reduced endothelial occludin content: Vascular endothelial growth factor decreases occludin content in retinal endothelial cells
    • Penn State Retina Research Group et al. 9836530 1:CAS:528: DyaK1cXnvVCru7Y%3D
    • Antonetti DA, Barber AJ, Khin S, Penn State Retina Research Group et al (1998) Vascular permeability in experimental diabetes is associated with reduced endothelial occludin content: vascular endothelial growth factor decreases occludin content in retinal endothelial cells. Diabetes 47:1953-1959
    • (1998) Diabetes , vol.47 , pp. 1953-1959
    • Antonetti, D.A.1    Barber, A.J.2    Khin, S.3
  • 102
    • 0036323373 scopus 로고    scopus 로고
    • Hydrocortisone decrease retinal endothelial cell water and solute flux coincident with increased content and decreased phosphorylation of occludin
    • 11841574 1:CAS:528:DC%2BD38XhslyisLg%3D
    • Antonetti DA, Wolpert EB, DeMaio L et al (2002) Hydrocortisone decrease retinal endothelial cell water and solute flux coincident with increased content and decreased phosphorylation of occludin. J Neurochem 80:667-677
    • (2002) J Neurochem , vol.80 , pp. 667-677
    • Antonetti, D.A.1    Wolpert, E.B.2    Demaio, L.3
  • 103
    • 0032509788 scopus 로고    scopus 로고
    • Corticosteroids inhibit the expression of the vascular endothelial growth factor gene in human vascular smooth muscle cells
    • 9543253 1:CAS:528:DyaK1cXhslOjsr4%3D
    • Nauck M, Karakiulakis G, Perruchoud AP et al (1998) Corticosteroids inhibit the expression of the vascular endothelial growth factor gene in human vascular smooth muscle cells. Eur J Pharmacol 341:309-315
    • (1998) Eur J Pharmacol , vol.341 , pp. 309-315
    • Nauck, M.1    Karakiulakis, G.2    Perruchoud, A.P.3
  • 104
    • 62449171859 scopus 로고    scopus 로고
    • Three-year follow-up of a randomized clinical trial comparing focal/grid laser photocoagulation and intravitreal triamcinolone for diabetic macular edema
    • Diabetic Retinopathy Clinical Research Network
    • Diabetic Retinopathy Clinical Research Network (2009) Three-year follow-up of a randomized clinical trial comparing focal/grid laser photocoagulation and intravitreal triamcinolone for diabetic macular edema. Arch Ophthalmol 127:245-251
    • (2009) Arch Ophthalmol , vol.127 , pp. 245-251
  • 105
    • 77952779304 scopus 로고    scopus 로고
    • Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema
    • Diabetic Retinopathy Clinical Research Network
    • Diabetic Retinopathy Clinical Research Network (2010) Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Ophthalmology 117:1064-1077.e35
    • (2010) Ophthalmology , vol.117
  • 106
    • 79953299899 scopus 로고    scopus 로고
    • Expanded 2-year follow-up of ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema
    • Diabetic Retinopathy Clinical Research Network
    • Diabetic Retinopathy Clinical Research Network (2011) Expanded 2-year follow-up of ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Ophthalmology 118:609-614
    • (2011) Ophthalmology , vol.118 , pp. 609-614
  • 107
    • 79953329178 scopus 로고    scopus 로고
    • Long-term benefit of sustained-delivery fluocinolone acetonide vitreous inserts for diabetic macular edema
    • FAME Study Group et al. 21459216
    • Campochiaro PA, Brown DM, Pearson A, Ciulla T, FAME Study Group et al (2011) Long-term benefit of sustained-delivery fluocinolone acetonide vitreous inserts for diabetic macular edema. Ophthalmology 118:626-635
    • (2011) Ophthalmology , vol.118 , pp. 626-635
    • Campochiaro, P.A.1    Brown, D.M.2    Pearson, A.3    Ciulla, T.4
  • 108
    • 77749330682 scopus 로고    scopus 로고
    • Randomized controlled trial of an intravitreous dexamethasone drug delivery system in patients with diabetic macular edema
    • 20212197 1:CAS:528:DC%2BC3cXktlSrur4%3D
    • Haller JA, Kuppermann BD, Blumenkranz MS et al (2010) Randomized controlled trial of an intravitreous dexamethasone drug delivery system in patients with diabetic macular edema. Arch Ophthalmol 128:289-296
    • (2010) Arch Ophthalmol , vol.128 , pp. 289-296
    • Haller, J.A.1    Kuppermann, B.D.2    Blumenkranz, M.S.3
  • 109
    • 0025959116 scopus 로고
    • Evaluation of a single intravitreal injection of dexamethasone phosphate in vitrectomy surgery for diabetic retinopathy complications
    • 2004725 1:STN:280:DyaK3M7mvFehtg%3D%3D
    • Blankenship GW (1991) Evaluation of a single intravitreal injection of dexamethasone phosphate in vitrectomy surgery for diabetic retinopathy complications. Graefes Arch Clin Exp Ophthalmol 229:62-65
    • (1991) Graefes Arch Clin Exp Ophthalmol , vol.229 , pp. 62-65
    • Blankenship, G.W.1
  • 110
    • 40849085554 scopus 로고    scopus 로고
    • Intravitreal steroids for macular edema: The past, the present, and the future
    • 18348879
    • Cunningham MA, Edelman JL, Kaushal S (2008) Intravitreal steroids for macular edema: the past, the present, and the future. Surv Ophthalmol 53:139-149
    • (2008) Surv Ophthalmol , vol.53 , pp. 139-149
    • Cunningham, M.A.1    Edelman, J.L.2    Kaushal, S.3
  • 112
    • 67650246081 scopus 로고    scopus 로고
    • Role of steroids in the treatment of diabetic macular edema
    • 19349792
    • Kuo CH, Gillies MC (2009) Role of steroids in the treatment of diabetic macular edema. Int Ophthalmol Clin 49:121-134
    • (2009) Int Ophthalmol Clin , vol.49 , pp. 121-134
    • Kuo, C.H.1    Gillies, M.C.2
  • 113
  • 114
    • 66149151043 scopus 로고    scopus 로고
    • Role of steroids in the management of diabetic macular edema and proliferative diabetic retinopathy
    • 19373693
    • Silva PS, Sun JK, Aiello LP (2009) Role of steroids in the management of diabetic macular edema and proliferative diabetic retinopathy. Semin Ophthalmol 24:93-99
    • (2009) Semin Ophthalmol , vol.24 , pp. 93-99
    • Silva, P.S.1    Sun, J.K.2    Aiello, L.P.3
  • 115
    • 65349122995 scopus 로고    scopus 로고
    • Intravitreal triamcinolone acetonide injection for treatment of refractory diabetic macular edema: A systematic review
    • 19410949
    • Yilmaz T, Weaver CD, Gallagher MJ et al (2009) Intravitreal triamcinolone acetonide injection for treatment of refractory diabetic macular edema: a systematic review. Ophthalmology 116:902-911
    • (2009) Ophthalmology , vol.116 , pp. 902-911
    • Yilmaz, T.1    Weaver, C.D.2    Gallagher, M.J.3
  • 116
    • 33748260374 scopus 로고    scopus 로고
    • Intravitreal triamcinolone acetonide for diffuse diabetic macular oedema: 6-month results of a prospective controlled trial
    • 16965492 1:CAS:528:DC%2BD28Xht1Wjt77L
    • Audren F, Erginay A, Haouchine B et al (2006) Intravitreal triamcinolone acetonide for diffuse diabetic macular oedema: 6-month results of a prospective controlled trial. Acta Ophthalmol Scand 84:624-630
    • (2006) Acta Ophthalmol Scand , vol.84 , pp. 624-630
    • Audren, F.1    Erginay, A.2    Haouchine, B.3
  • 117
    • 0842267262 scopus 로고    scopus 로고
    • Intravitreal triamcinolone acetonide for diabetic diffuse macular edema: Preliminary results of a prospective controlled trial
    • 15019365
    • Massin P, Audren F, Haouchine B et al (2004) Intravitreal triamcinolone acetonide for diabetic diffuse macular edema: preliminary results of a prospective controlled trial. Ophthalmology 111:218-224
    • (2004) Ophthalmology , vol.111 , pp. 218-224
    • Massin, P.1    Audren, F.2    Haouchine, B.3
  • 118
    • 26844431631 scopus 로고    scopus 로고
    • Intravitreal triamcinolone compared with macular laser grid photocoagulation for the treatment of cystoid macular edema
    • 16226521 1:CAS:528:DC%2BD2MXhtFSmt7%2FE
    • Avitabile T, Longo A, Reibaldi A (2005) Intravitreal triamcinolone compared with macular laser grid photocoagulation for the treatment of cystoid macular edema. Am J Ophthalmol 140:695-702
    • (2005) Am J Ophthalmol , vol.140 , pp. 695-702
    • Avitabile, T.1    Longo, A.2    Reibaldi, A.3
  • 119
    • 33745884399 scopus 로고    scopus 로고
    • Intravitreal triamcinolone acetonide for diabetic macular edema: A prospective, randomized study
    • 16808682 1:CAS:528:DC%2BD28XmtlGrtb0%3D
    • Jonas JB, Kampperter BA, Harder B et al (2006) Intravitreal triamcinolone acetonide for diabetic macular edema: a prospective, randomized study. J Ocul Pharmacol Ther 22:200-207
    • (2006) J Ocul Pharmacol Ther , vol.22 , pp. 200-207
    • Jonas, J.B.1    Kampperter, B.A.2    Harder, B.3
  • 120
    • 33747623255 scopus 로고    scopus 로고
    • Intravitreal triamcinolone for refractory diabetic macular edema two-year results of a double-masked, placebo-controlled, randomized clinical trial
    • 16828501
    • Gillies MC, Sutter FK, Simpson JM et al (2006) Intravitreal triamcinolone for refractory diabetic macular edema two-year results of a double-masked, placebo-controlled, randomized clinical trial. Ophthalmology 113:1533-1538
    • (2006) Ophthalmology , vol.113 , pp. 1533-1538
    • Gillies, M.C.1    Sutter, F.K.2    Simpson, J.M.3
  • 121
    • 7444245438 scopus 로고    scopus 로고
    • Intravitreal triamcinolone for diabetic macular edema that persists after laser treatment: Three-month efficacy and safety results of a prospective, randomized, double-masked, placebo controlled clinical trial
    • 15522370
    • Sutter FK, Simpson JM, Gillies MC (2004) Intravitreal triamcinolone for diabetic macular edema that persists after laser treatment: three-month efficacy and safety results of a prospective, randomized, double-masked, placebo controlled clinical trial. Ophthalmology 111:2044-2049
    • (2004) Ophthalmology , vol.111 , pp. 2044-2049
    • Sutter, F.K.1    Simpson, J.M.2    Gillies, M.C.3
  • 122
    • 73349135368 scopus 로고    scopus 로고
    • Exploratory analysis of diabetic retinopathy progression through 3 years in a randomized clinical trial that compares intravitreal triamcinolone acetonide with focal/grid photocoagulation
    • 20008708 1:CAS:528:DC%2BC3cXktleksQ%3D%3D
    • Bressler NM, Edwards AR, Beck RW et al (2009) Exploratory analysis of diabetic retinopathy progression through 3 years in a randomized clinical trial that compares intravitreal triamcinolone acetonide with focal/grid photocoagulation. Arch Ophthalmol 127:1566-1571
    • (2009) Arch Ophthalmol , vol.127 , pp. 1566-1571
    • Bressler, N.M.1    Edwards, A.R.2    Beck, R.W.3
  • 123
    • 70350574742 scopus 로고    scopus 로고
    • Five-year results of a randomized trial with open-label extension of triamcinolone acetonide for refractory diabetic macular edema
    • 19796823
    • Gillies MC, Simpson JM, Gaston C et al (2009) Five-year results of a randomized trial with open-label extension of triamcinolone acetonide for refractory diabetic macular edema. Ophthalmology 116:2182-2187
    • (2009) Ophthalmology , vol.116 , pp. 2182-2187
    • Gillies, M.C.1    Simpson, J.M.2    Gaston, C.3
  • 124
    • 79958268827 scopus 로고    scopus 로고
    • Randomized trial evaluating short-term effects of intravitreal ranibizumab or triamcinolone acetonide on macular edema after focal/grid laser for diabetic macular edema in eyes also receiving panretinal photocoagulation
    • Diabetic Retinopathy Clinical Research Network
    • Diabetic Retinopathy Clinical Research Network (2011) Randomized trial evaluating short-term effects of intravitreal ranibizumab or triamcinolone acetonide on macular edema after focal/grid laser for diabetic macular edema in eyes also receiving panretinal photocoagulation. Retina 31:1009-1027
    • (2011) Retina , vol.31 , pp. 1009-1027
  • 125
    • 79955597650 scopus 로고    scopus 로고
    • Intravitreal triamcinolone prior to laser treatment of diabetic macular edema: 24-month results of a randomized controlled trial
    • 21232801
    • Gillies MC, McAllister IL, Zhu M, Wong W, Louis D, Arnold JJ, Wong TY (2011) Intravitreal triamcinolone prior to laser treatment of diabetic macular edema: 24-month results of a randomized controlled trial. Ophthalmology 118:866-872
    • (2011) Ophthalmology , vol.118 , pp. 866-872
    • Gillies, M.C.1    McAllister, I.L.2    Zhu, M.3    Wong, W.4    Louis, D.5    Arnold, J.J.6    Wong, T.Y.7
  • 126
    • 76749136263 scopus 로고    scopus 로고
    • Intravitreal triamcinolone as an adjunct to standard laser therapy in coexisting high-risk proliferative diabetic retinopathy and clinically significant macular edema
    • 20057344
    • Mirshahi A, Shenazandi H, Lashay A et al (2010) Intravitreal triamcinolone as an adjunct to standard laser therapy in coexisting high-risk proliferative diabetic retinopathy and clinically significant macular edema. Retina 30:254-259
    • (2010) Retina , vol.30 , pp. 254-259
    • Mirshahi, A.1    Shenazandi, H.2    Lashay, A.3
  • 127
    • 57949110908 scopus 로고    scopus 로고
    • Association of vitreous inflammatory factors with diabetic macular edema
    • 19118698
    • Funatsu H, Noma H, Mimura T et al (2009) Association of vitreous inflammatory factors with diabetic macular edema. Ophthalmology 116:73-79
    • (2009) Ophthalmology , vol.116 , pp. 73-79
    • Funatsu, H.1    Noma, H.2    Mimura, T.3
  • 128
    • 61549134800 scopus 로고    scopus 로고
    • Evaluation of safety and performance of an applicator for a novel intravitreal dexamethasone drug delivery system for the treatment of macular edema
    • 18827732
    • Haller JA, Dugel P, Weinberg DV et al (2009) Evaluation of safety and performance of an applicator for a novel intravitreal dexamethasone drug delivery system for the treatment of macular edema. Retina 29:46-51
    • (2009) Retina , vol.29 , pp. 46-51
    • Haller, J.A.1    Dugel, P.2    Weinberg, D.V.3
  • 129
    • 33947275043 scopus 로고    scopus 로고
    • Dexamethasone DDS Phase II Study Group. Randomized controlled study of an intravitreous dexamethasone drug delivery system in patients with persistent macular edema
    • 17353400 1:CAS:528:DC%2BD2sXjvVKktLc%3D
    • Kuppermann BD, Blumenkranz MS, Haller JA et al (2007) Dexamethasone DDS Phase II Study Group. Randomized controlled study of an intravitreous dexamethasone drug delivery system in patients with persistent macular edema. Arch Ophthalmol 125:309-317
    • (2007) Arch Ophthalmol , vol.125 , pp. 309-317
    • Kuppermann, B.D.1    Blumenkranz, M.S.2    Haller, J.A.3
  • 130
    • 23044445144 scopus 로고    scopus 로고
    • Difference in clearance of intravitreal triamcinolone acetonide between vitrectomized and non-vitrectomized eyes
    • 16077349
    • Chin HS, Park TS, Moon YS, Oh JH (2005) Difference in clearance of intravitreal triamcinolone acetonide between vitrectomized and non-vitrectomized eyes. Retina 25:556-560
    • (2005) Retina , vol.25 , pp. 556-560
    • Chin, H.S.1    Park, T.S.2    Moon, Y.S.3    Oh, J.H.4
  • 131
    • 79955558683 scopus 로고    scopus 로고
    • Dexamethasone intravitreal implant for treatment of diabetic macular edema in vitrectomized patients
    • for the Ozurdex Champlain Study Group et al. 21487341 1:CAS:528:DC%2BC38XjtlOitb4%3D
    • Boyer DS, Faber D, Gupta S, for the Ozurdex Champlain Study Group et al (2011) Dexamethasone intravitreal implant for treatment of diabetic macular edema in vitrectomized patients. Retina 31:915-923
    • (2011) Retina , vol.31 , pp. 915-923
    • Boyer, D.S.1    Faber, D.2    Gupta, S.3
  • 133
    • 84870825728 scopus 로고    scopus 로고
    • (ClinicalTrials.gov identifier NCT00168337). US National Institutes of Health, ClinicalTrials.gov (online) Accessed 24 Sep 2010
    • A study of the safety and efficacy of a new treatment for diabetic macular edema (ClinicalTrials.gov identifier NCT00168337). US National Institutes of Health, ClinicalTrials.gov (online). Available from http://www.clinicaltrials.gov. Accessed 24 Sep 2010
    • A Study of the Safety and Efficacy of A New Treatment for Diabetic Macular Edema
  • 134
    • 33646925637 scopus 로고    scopus 로고
    • Fluocinolone acetonide implant (Retisert) for non infectious posterior uveitis: Thirty-four-week results of a multicenter randomized clinical study
    • Fluocinolone Acetonide Uveitis Study Group et al. 16690128
    • Jaffe GJ, Martin D, Callanan D, Fluocinolone Acetonide Uveitis Study Group et al (2006) Fluocinolone acetonide implant (Retisert) for non infectious posterior uveitis: thirty-four-week results of a multicenter randomized clinical study. Ophthalmology 113:1020-1027
    • (2006) Ophthalmology , vol.113 , pp. 1020-1027
    • Jaffe, G.J.1    Martin, D.2    Callanan, D.3
  • 135
    • 79961044911 scopus 로고    scopus 로고
    • Fluocinolone acetonide intravitreal implant for diabetic macular edema: A 3-year multicenter, randomized, controlled clinical trial
    • 21813090
    • Pearson PA, Comstock TL, Ip M et al (2011) Fluocinolone acetonide intravitreal implant for diabetic macular edema: a 3-year multicenter, randomized, controlled clinical trial. Ophthalmology 118:1580-1587
    • (2011) Ophthalmology , vol.118 , pp. 1580-1587
    • Pearson, P.A.1    Comstock, T.L.2    Ip, M.3
  • 136
    • 77954349303 scopus 로고    scopus 로고
    • Sustained ocular delivery of fluocinolone acetonide by an intravitreal insert
    • Famous Study Group et al. 20202684
    • Campochiaro PA, Hafiz G, Shah SM, Famous Study Group et al (2010) Sustained ocular delivery of fluocinolone acetonide by an intravitreal insert. Ophthalmology 117:1393-1399
    • (2010) Ophthalmology , vol.117 , pp. 1393-1399
    • Campochiaro, P.A.1    Hafiz, G.2    Shah, S.M.3
  • 137
    • 84867099927 scopus 로고    scopus 로고
    • Sustained delivery fluocinolone acetonide vitreous inserts provide benefit for at least 3 years in patients with diabetic macular edema
    • Campochiaro PA, Brown DM, Pearson A et al (2012) Sustained delivery fluocinolone acetonide vitreous inserts provide benefit for at least 3 years in patients with diabetic macular edema. Ophthalmology 119:2125-2132
    • (2012) Ophthalmology , vol.119 , pp. 2125-2132
    • Campochiaro, P.A.1    Brown, D.M.2    Pearson, A.3
  • 138
    • 84859782745 scopus 로고    scopus 로고
    • New approaches for the treatment of diabetic macular oedema: Recommendations by an expert panel
    • 22241014 1:CAS:528:DC%2BC38XlsFSgt7c%3D
    • Bandello F, Cunha-Vaz J, Chong NV et al (2012) New approaches for the treatment of diabetic macular oedema: recommendations by an expert panel. Eye 26:485-493
    • (2012) Eye , vol.26 , pp. 485-493
    • Bandello, F.1    Cunha-Vaz, J.2    Chong, N.V.3
  • 139
    • 79251606719 scopus 로고    scopus 로고
    • Safety and efficacy of ranibizumab in diabetic macular edema (RESOLVE Study): A 12-month, randomized, controlled, double-masked, multicenter phase II study
    • 20980427 1:CAS:528:DC%2BC3cXhs1SisrzO
    • Massin P, Bandello F, Garweg JG et al (2010) Safety and efficacy of ranibizumab in diabetic macular edema (RESOLVE Study): a 12-month, randomized, controlled, double-masked, multicenter phase II study. Diabetes Care 33:2399-2405
    • (2010) Diabetes Care , vol.33 , pp. 2399-2405
    • Massin, P.1    Bandello, F.2    Garweg, J.G.3
  • 140
    • 84863401792 scopus 로고    scopus 로고
    • Ranibizumab for diabetic macular edema: Results from 2 phase III randomized trials: RISE and RIDE
    • RISE and RIDE Research Group et al. 22330964
    • Nguyen QD, Brown DM, Marcus DM, RISE and RIDE Research Group et al (2012) Ranibizumab for diabetic macular edema: results from 2 phase III randomized trials: RISE and RIDE. Ophthalmology 119:789-801
    • (2012) Ophthalmology , vol.119 , pp. 789-801
    • Nguyen, Q.D.1    Brown, D.M.2    Marcus, D.M.3
  • 141
    • 70350567637 scopus 로고    scopus 로고
    • Primary end point (six months) results of the ranibizumab for edema of the macula in diabetes (READ-2) study
    • READ-2 Study Group et al. 19700194
    • Nguyen QD, Shah SM, Heier JS, READ-2 Study Group et al (2009) Primary end point (six months) results of the ranibizumab for edema of the macula in diabetes (READ-2) study. Ophthalmology 116:2175-2181.e1
    • (2009) Ophthalmology , vol.116
    • Nguyen, Q.D.1    Shah, S.M.2    Heier, J.S.3
  • 142
    • 78049293726 scopus 로고    scopus 로고
    • Two-year outcomes of the ranibizumab for edema of the mAcula in diabetes (READ-2) study
    • READ-2 Study Group et al. 20855114
    • Nguyen QD, Shah SM, Khwaja AA, READ-2 Study Group et al (2010) Two-year outcomes of the ranibizumab for edema of the mAcula in diabetes (READ-2) study. Ophthalmology 117:2146-2151
    • (2010) Ophthalmology , vol.117 , pp. 2146-2151
    • Nguyen, Q.D.1    Shah, S.M.2    Khwaja, A.A.3
  • 143
    • 79953311138 scopus 로고    scopus 로고
    • The RESTORE study: Ranibizumab monotherapy or combined with laser versus laser monotherapy for diabetic macular edema
    • RESTORE Study Group et al. 21459215
    • Mitchell P, Bandello F, Schmidt-Erfurth U, RESTORE Study Group et al (2011) The RESTORE study: ranibizumab monotherapy or combined with laser versus laser monotherapy for diabetic macular edema. Ophthalmology 118:615-625
    • (2011) Ophthalmology , vol.118 , pp. 615-625
    • Mitchell, P.1    Bandello, F.2    Schmidt-Erfurth, U.3
  • 144
    • 33845191304 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is a critical stimulus for diabetic macular edema
    • 17046701 1:CAS:528:DC%2BD28Xht12msLfE
    • Nguyen QD, Tatlipinar S, Shah SM et al (2006) Vascular endothelial growth factor is a critical stimulus for diabetic macular edema. Am J Ophthalmol 142:961-969
    • (2006) Am J Ophthalmol , vol.142 , pp. 961-969
    • Nguyen, Q.D.1    Tatlipinar, S.2    Shah, S.M.3
  • 145
    • 84873097688 scopus 로고    scopus 로고
    • (ClinicalTrials.gov identifier NCT01476449). US National Institutes of Health, ClinicalTrials.gov (online) Accessed 24 Sep 2012
    • Dosing study of ranibizumab for diabetic retinal and macular edema. (ClinicalTrials.gov identifier NCT01476449). US National Institutes of Health, ClinicalTrials.gov (online). Available from http://www.clinicaltrials.gov. Accessed 24 Sep 2012
    • Dosing Study of Ranibizumab for Diabetic Retinal and Macular Edema
  • 147
    • 84873097831 scopus 로고    scopus 로고
    • (ClinicalTrials.gov identifier NCT01077401). US National Institutes of Health, ClinicalTrials.gov (online) Accessed 24 Sep 2012
    • Ranibizumab for edema of the macula in diabetes: Protocol 3 with high dose - the READ 3 Study (ClinicalTrials.gov identifier NCT01077401). US National Institutes of Health, ClinicalTrials.gov (online). Available from http://www.clinicaltrials.gov. Accessed 24 Sep 2012
    • Ranibizumab for Edema of the Macula in Diabetes: Protocol 3 with High Dose - The READ 3 Study
  • 148
    • 80255133183 scopus 로고    scopus 로고
    • Panretinal photocoagulation (PRP) versus PRP plus intravitreal ranibizumab for high-risk proliferative diabetic retinopathy
    • 10.1111/j.1755-3768.2011.02184.x 21726427 1:CAS:528:DC%2BC3MXhs1GltL7I
    • Filho JA, Messias A, Almeida FP et al (2011) Panretinal photocoagulation (PRP) versus PRP plus intravitreal ranibizumab for high-risk proliferative diabetic retinopathy. Acta Ophthalmol 89:e567-e572. doi: 10.1111/j.1755-3768. 2011.02184.x
    • (2011) Acta Ophthalmol , vol.89
    • Filho, J.A.1    Messias, A.2    Almeida, F.P.3
  • 150
    • 34748876124 scopus 로고    scopus 로고
    • A phase II randomized clinical trial of intravitreal bevacizumab for diabetic macular edema
    • Diabetic Retinopathy Clinical Research Network 17698196
    • Diabetic Retinopathy Clinical Research Network, Scott IU, Edwards AR, Beck RW, Bressler NM et al (2007) A phase II randomized clinical trial of intravitreal bevacizumab for diabetic macular edema. Ophthalmology 114:1860-1867
    • (2007) Ophthalmology , vol.114 , pp. 1860-1867
    • Scott, I.U.1    Edwards, A.R.2    Beck, R.W.3    Bressler, N.M.4
  • 151
    • 67650043196 scopus 로고    scopus 로고
    • Efficacy of 1.25 MG versus 2.5 MG intravitreal bevacizumab for diabetic macular edema: Six-month results of a randomized controlled trial
    • 19287286
    • Lam DS, Lai TY, Lee VY et al (2009) Efficacy of 1.25 MG versus 2.5 MG intravitreal bevacizumab for diabetic macular edema: six-month results of a randomized controlled trial. Retina 29:292-299
    • (2009) Retina , vol.29 , pp. 292-299
    • Lam, D.S.1    Lai, T.Y.2    Lee, V.Y.3
  • 152
    • 68049148355 scopus 로고    scopus 로고
    • Primary intravitreal bevacizumab for diffuse diabetic macular edema: The Pan-American Collaborative Retina Study Group at 24 months
    • Pan-American Collaborative Retina Study Group et al. 19545900
    • Arevalo JF, Sanchez JG, Wu L, Pan-American Collaborative Retina Study Group et al (2009) Primary intravitreal bevacizumab for diffuse diabetic macular edema: the Pan-American Collaborative Retina Study Group at 24 months. Ophthalmology 116:1488-1497
    • (2009) Ophthalmology , vol.116 , pp. 1488-1497
    • Arevalo, J.F.1    Sanchez, J.G.2    Wu, L.3
  • 153
    • 58149242792 scopus 로고    scopus 로고
    • Long-term effect of intravitreal bevacizumab (avastin) in patients with chronic diffuse diabetic macular edema
    • 18779710
    • Kook D, Wolf A, Kreutzer T et al (2008) Long-term effect of intravitreal bevacizumab (avastin) in patients with chronic diffuse diabetic macular edema. Retina 28:1053-1060
    • (2008) Retina , vol.28 , pp. 1053-1060
    • Kook, D.1    Wolf, A.2    Kreutzer, T.3
  • 154
    • 77952889192 scopus 로고    scopus 로고
    • A prospective randomized trial of intravitreal bevacizumab or laser therapy in the management of diabetic macular edema (BOLT study) 12-month data: Report 2
    • 20416952
    • Michaelides M, Kaines A, Hamilton RD et al (2010) A prospective randomized trial of intravitreal bevacizumab or laser therapy in the management of diabetic macular edema (BOLT study) 12-month data: report 2. Ophthalmology 117:1078-1086.e2
    • (2010) Ophthalmology , vol.117
    • Michaelides, M.1    Kaines, A.2    Hamilton, R.D.3
  • 155
    • 84865593623 scopus 로고    scopus 로고
    • A 2-year prospective randomized controlled trial of intravitreal bevacizumab or laser therapy (BOLT) in the management of diabetic macular edema: 24-month data: Report 3
    • Rajendram R, Fraser-Bell S, Kaines A et al (2012) A 2-year prospective randomized controlled trial of intravitreal bevacizumab or laser therapy (BOLT) in the management of diabetic macular edema: 24-month data: report 3. Arch Ophthalmol 130:972-979
    • (2012) Arch Ophthalmol , vol.130 , pp. 972-979
    • Rajendram, R.1    Fraser-Bell, S.2    Kaines, A.3
  • 156
    • 38349162286 scopus 로고    scopus 로고
    • Intravitreal triamcinolone versus bevacizumab for treatment of refractory diabetic macular oedema (IBEME study)
    • 17965109 1:STN:280:DC%2BD2sjmtFWisw%3D%3D
    • Paccola L, Costa RA, Folgosa MS et al (2008) Intravitreal triamcinolone versus bevacizumab for treatment of refractory diabetic macular oedema (IBEME study). Br J Ophthalmol 92:76-80
    • (2008) Br J Ophthalmol , vol.92 , pp. 76-80
    • Paccola, L.1    Costa, R.A.2    Folgosa, M.S.3
  • 157
    • 43049104479 scopus 로고    scopus 로고
    • Comparative therapy evaluation of intravitreal bevacizumab and triamcinolone acetonide on persistent diffuse diabetic macular edema
    • 18328456 1:CAS:528:DC%2BD1cXlsFChsr4%3D
    • Shimura M, Nakazawa T, Yasuda K et al (2008) Comparative therapy evaluation of intravitreal bevacizumab and triamcinolone acetonide on persistent diffuse diabetic macular edema. Am J Ophthalmol 145:854-861
    • (2008) Am J Ophthalmol , vol.145 , pp. 854-861
    • Shimura, M.1    Nakazawa, T.2    Yasuda, K.3
  • 158
    • 67349168190 scopus 로고    scopus 로고
    • Randomized trial of intravitreal bevacizumab alone or combined with triamcinolone versus macular photocoagulation in diabetic macular edema
    • 19376585
    • Soheilian M, Ramezani A, Obudi A et al (2009) Randomized trial of intravitreal bevacizumab alone or combined with triamcinolone versus macular photocoagulation in diabetic macular edema. Ophthalmology 116:1142-1150
    • (2009) Ophthalmology , vol.116 , pp. 1142-1150
    • Soheilian, M.1    Ramezani, A.2    Obudi, A.3
  • 159
    • 33748982649 scopus 로고    scopus 로고
    • Intravitreal bevacizumab (Avastin) in the treatment of proliferative diabetic retinopathy
    • 17011951
    • Avery RL, Pearlman J, Pieramici DJ et al (2006) Intravitreal bevacizumab (Avastin) in the treatment of proliferative diabetic retinopathy. Ophthalmology 113:1695.e1-15
    • (2006) Ophthalmology , vol.113
    • Avery, R.L.1    Pearlman, J.2    Pieramici, D.J.3
  • 160
    • 33749631288 scopus 로고    scopus 로고
    • Intravitreal bevacizumab (Avastin) for persistent new vessels in diabetic retinopathy (IBEPE study)
    • 17151487
    • Jorge R, Costa RA, Calucci D et al (2006) Intravitreal bevacizumab (Avastin) for persistent new vessels in diabetic retinopathy (IBEPE study). Retina 26:1006-1013
    • (2006) Retina , vol.26 , pp. 1006-1013
    • Jorge, R.1    Costa, R.A.2    Calucci, D.3
  • 161
    • 56049104902 scopus 로고    scopus 로고
    • Intravitreal bevacizumab in active progressive proliferative diabetic retinopathy
    • 18696095 1:CAS:528:DC%2BD1cXhtlart7nF
    • Moradian S, Ahmadieh H, Malihi M et al (2008) Intravitreal bevacizumab in active progressive proliferative diabetic retinopathy. Graefes Arch Clin Exp Ophthalmol 246:1699-1705
    • (2008) Graefes Arch Clin Exp Ophthalmol , vol.246 , pp. 1699-1705
    • Moradian, S.1    Ahmadieh, H.2    Malihi, M.3
  • 162
    • 70349150585 scopus 로고    scopus 로고
    • Intravitreal bevacizumab and panretinal photocoagulation for proliferative diabetic retinopathy associated with vitreous hemorrhage
    • 19672218
    • Huang YH, Yeh PT, Chen MS et al (2009) Intravitreal bevacizumab and panretinal photocoagulation for proliferative diabetic retinopathy associated with vitreous hemorrhage. Retina 29:1134-1140
    • (2009) Retina , vol.29 , pp. 1134-1140
    • Huang, Y.H.1    Yeh, P.T.2    Chen, M.S.3
  • 163
    • 43749087641 scopus 로고    scopus 로고
    • Bevacizumab-augmented retinal laser photocoagulation in proliferative diabetic retinopathy: A randomized double-masked clinical trial
    • 18320520 1:STN:280:DC%2BD1c7mtFOjug%3D%3D
    • Mirshahi A, Roohipoor R, Lashay A et al (2008) Bevacizumab-augmented retinal laser photocoagulation in proliferative diabetic retinopathy: a randomized double-masked clinical trial. Eur J Ophthalmol 18:263-269
    • (2008) Eur J Ophthalmol , vol.18 , pp. 263-269
    • Mirshahi, A.1    Roohipoor, R.2    Lashay, A.3
  • 164
    • 60849085180 scopus 로고    scopus 로고
    • Intracameral bevacizumab effectively reduces aqueous vascular endothelial growth factor concentrations in neovascular glaucoma
    • 18617542 1:STN:280:DC%2BD1M%2FpvFarug%3D%3D
    • Grover S, Gupta S, Sharma R et al (2009) Intracameral bevacizumab effectively reduces aqueous vascular endothelial growth factor concentrations in neovascular glaucoma. Br J Ophthalmol 93:273-274
    • (2009) Br J Ophthalmol , vol.93 , pp. 273-274
    • Grover, S.1    Gupta, S.2    Sharma, R.3
  • 165
    • 55149095947 scopus 로고    scopus 로고
    • Intravitreal bevacizumab (Avastin) injection for neovascular glaucoma: A survey on 23 cases throughout 12-month follow-up
    • 19032174 1:CAS:528:DC%2BD1cXhsVyntLfL
    • Costagliola C, Cipollone U, Rinaldi M et al (2008) Intravitreal bevacizumab (Avastin) injection for neovascular glaucoma: a survey on 23 cases throughout 12-month follow-up. Br J Clin Pharmacol 66:667-673
    • (2008) Br J Clin Pharmacol , vol.66 , pp. 667-673
    • Costagliola, C.1    Cipollone, U.2    Rinaldi, M.3
  • 166
    • 73349097560 scopus 로고    scopus 로고
    • Concentration of vascular endothelial growth factor after intracameral bevacizumab injection in eyes with neovascular glaucoma
    • 19794946
    • Lim TH, Bae SH, Cho YJ et al (2009) Concentration of vascular endothelial growth factor after intracameral bevacizumab injection in eyes with neovascular glaucoma. Korean J Ophthalmol 23:188-192
    • (2009) Korean J Ophthalmol , vol.23 , pp. 188-192
    • Lim, T.H.1    Bae, S.H.2    Cho, Y.J.3
  • 167
    • 68149126252 scopus 로고    scopus 로고
    • Intravitreal bevacizumab and aqueous shunting surgery for neovascular glaucoma: Safety and efficacy
    • 19606170
    • Eid TM, Radwan A, el-Manawy W, el-Hawary I (2009) Intravitreal bevacizumab and aqueous shunting surgery for neovascular glaucoma: safety and efficacy. Can J Ophthalmol 44:451-456
    • (2009) Can J Ophthalmol , vol.44 , pp. 451-456
    • Eid, T.M.1    Radwan, A.2    El-Manawy, W.3    El-Hawary, I.4
  • 168
    • 70549104747 scopus 로고    scopus 로고
    • Intravitreal bevacizumab as an adjunct treatment for neovascular glaucoma
    • 19551676
    • Hasanreisoglu M, Weinberger D, Mimouni K et al (2009) Intravitreal bevacizumab as an adjunct treatment for neovascular glaucoma. Eur J Ophthalmol 19:607-612
    • (2009) Eur J Ophthalmol , vol.19 , pp. 607-612
    • Hasanreisoglu, M.1    Weinberger, D.2    Mimouni, K.3
  • 169
    • 73949136339 scopus 로고    scopus 로고
    • Intravitreal bevacizumab combined with panretinal photocoagulation in the treatment of open angle neovascular glaucoma
    • 19882572
    • Ciftci S, Sakalar YB, Unlu K et al (2009) Intravitreal bevacizumab combined with panretinal photocoagulation in the treatment of open angle neovascular glaucoma. Eur J Ophthalmol 19:1028-1033
    • (2009) Eur J Ophthalmol , vol.19 , pp. 1028-1033
    • Ciftci, S.1    Sakalar, Y.B.2    Unlu, K.3
  • 170
    • 11144239923 scopus 로고    scopus 로고
    • Pegaptanib for neovascular age-related macular degeneration
    • VEGF Inhibition Study in Ocular Neovascularization Clinical Trial Group et al. 15625332 1:CAS:528:DC%2BD2MXhslyntw%3D%3D
    • Gragoudas ES, Adamis AP, Cunningham ET Jr, VEGF Inhibition Study in Ocular Neovascularization Clinical Trial Group et al (2004) Pegaptanib for neovascular age-related macular degeneration. N Engl J Med 351:2805-2816
    • (2004) N Engl J Med , vol.351 , pp. 2805-2816
    • Gragoudas, E.S.1    Adamis, A.P.2    Cunningham, Jr.E.T.3
  • 171
    • 25844513658 scopus 로고    scopus 로고
    • A phase II randomized double-masked trial of pegaptanib, an anti-vascular endothelial growth factor aptamer, for diabetic macular edema
    • Macugen Diabetic Retinopathy Study Group et al. 16154196
    • Cunningham ET Jr, Adamis AP, Altaweel M, Macugen Diabetic Retinopathy Study Group et al (2005) A phase II randomized double-masked trial of pegaptanib, an anti-vascular endothelial growth factor aptamer, for diabetic macular edema. Ophthalmology 112:1747-1757
    • (2005) Ophthalmology , vol.112 , pp. 1747-1757
    • Cunningham, Jr.E.T.1    Adamis, A.P.2    Altaweel, M.3
  • 172
    • 84856386357 scopus 로고    scopus 로고
    • Changes in vision- and health-related quality of life in patients with diabetic macular edema treated with pegaptanib sodium or sham
    • Macugen 1013 Study Group 21896838 1:CAS:528:DC%2BC3MXhtlWku7jI
    • Loftus JV, Sultan MB, Pleil AM, Macugen 1013 Study Group (2011) Changes in vision- and health-related quality of life in patients with diabetic macular edema treated with pegaptanib sodium or sham. Invest Ophthalmol Vis Sci 52:7498-7505
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 7498-7505
    • Loftus, J.V.1    Sultan, M.B.2    Pleil, A.M.3
  • 173
    • 79958012399 scopus 로고    scopus 로고
    • A phase 2/3, multicenter, randomized, double-masked, 2-year trial of pegaptanib sodium for the treatment of diabetic macular edema
    • Macugen 1013 Study Group et al. 21529957
    • Sultan MB, Zhou D, Loftus J, Macugen 1013 Study Group et al (2011) A phase 2/3, multicenter, randomized, double-masked, 2-year trial of pegaptanib sodium for the treatment of diabetic macular edema. Ophthalmology 118:1107-1118
    • (2011) Ophthalmology , vol.118 , pp. 1107-1118
    • Sultan, M.B.1    Zhou, D.2    Loftus, J.3
  • 174
    • 29644444716 scopus 로고    scopus 로고
    • Changes in retinal neovascularization after pegaptanib (Macugen) therapy in diabetic individuals
    • Macugen Diabetic Retinopathy Study Group et al. 16343627
    • Adamis AP, Altaweel M, Bressler NM, Macugen Diabetic Retinopathy Study Group et al (2006) Changes in retinal neovascularization after pegaptanib (Macugen) therapy in diabetic individuals. Ophthalmology 113:23-28
    • (2006) Ophthalmology , vol.113 , pp. 23-28
    • Adamis, A.P.1    Altaweel, M.2    Bressler, N.M.3
  • 175
    • 70350469069 scopus 로고    scopus 로고
    • Intravitreal injection of pegaptanib sodium for proliferative diabetic retinopathy
    • 19692371
    • González VH, Giuliari GP et al (2009) Intravitreal injection of pegaptanib sodium for proliferative diabetic retinopathy. Br J Ophthalmol 93:1474-1478
    • (2009) Br J Ophthalmol , vol.93 , pp. 1474-1478
    • González, V.H.1    Giuliari, G.P.2
  • 176
    • 77955612774 scopus 로고    scopus 로고
    • Use of pegaptanib for recurrent and non-clearing vitreous haemorrhage in proliferative diabetic retinopathy
    • 20224599 1:CAS:528:DC%2BC3cXhtVajt73P
    • Hornan D, Edmeades N, Krishnan R et al (2010) Use of pegaptanib for recurrent and non-clearing vitreous haemorrhage in proliferative diabetic retinopathy. Eye 24:1315-1319
    • (2010) Eye , vol.24 , pp. 1315-1319
    • Hornan, D.1    Edmeades, N.2    Krishnan, R.3
  • 177
    • 80052514329 scopus 로고    scopus 로고
    • The da VINCI Study: Phase 2 primary results of VEGF Trap-Eye in patients with diabetic macular edema
    • 21546089
    • Do DV, Schmidt-Erfurth U, Gonzalez VH et al (2011) The DA VINCI Study: phase 2 primary results of VEGF Trap-Eye in patients with diabetic macular edema. Ophthalmology 118:1819-1826
    • (2011) Ophthalmology , vol.118 , pp. 1819-1826
    • Do, D.V.1    Schmidt-Erfurth, U.2    Gonzalez, V.H.3
  • 178
    • 84864444516 scopus 로고    scopus 로고
    • One-year outcomes of the da VINCI Study of VEGF Trap-Eye in eyes with diabetic macular edema
    • DA VINCI Study Group et al. 22537617
    • Do DV, Nguyen QD, Boyer D, DA VINCI Study Group et al (2012) One-year outcomes of the DA VINCI Study of VEGF Trap-Eye in eyes with diabetic macular edema. Ophthalmology 119:1658-1665
    • (2012) Ophthalmology , vol.119 , pp. 1658-1665
    • Do, D.V.1    Nguyen, Q.D.2    Boyer, D.3
  • 179
    • 84873094014 scopus 로고    scopus 로고
    • (ClinicalTrials.gov identifier NCT00306904). US National Institutes of Health, ClinicalTrials.gov (online) Accessed 24 Sep 2012
    • Safety and efficacy study of small interfering RNA molecule (Cand5) to treat diabetic macular edema (ClinicalTrials.gov identifier NCT00306904). US National Institutes of Health, ClinicalTrials.gov (online). Available from http://www.clinicaltrials.gov. Accessed 24 Sep 2012
    • Safety and Efficacy Study of Small Interfering RNA Molecule (Cand5) to Treat Diabetic Macular Edema
  • 180
    • 77956397801 scopus 로고    scopus 로고
    • Intravitreal bevasiranib in exudative age-related macular degeneration or diabetic macular edema
    • Indian Wells
    • Singerman LJ (2007) Intravitreal bevasiranib in exudative age-related macular degeneration or diabetic macular edema. 25th annual meeting of the American Society of Retina Specialists, Indian Wells
    • (2007) 25th Annual Meeting of the American Society of Retina Specialists
    • Singerman, L.J.1
  • 181
    • 80755190097 scopus 로고    scopus 로고
    • Subconjunctival sirolimus in the treatment of diabetic macular edema
    • 21567211 1:CAS:528:DC%2BC3MXhtlylurrI
    • Krishnadev N, Forooghian F, Cukras C et al (2011) Subconjunctival sirolimus in the treatment of diabetic macular edema. Graefes Arch Clin Exp Ophthalmol 249:1627-1633
    • (2011) Graefes Arch Clin Exp Ophthalmol , vol.249 , pp. 1627-1633
    • Krishnadev, N.1    Forooghian, F.2    Cukras, C.3
  • 182
    • 84855305671 scopus 로고    scopus 로고
    • A randomized, dose-escalation study of subconjunctival and intravitreal injections of sirolimus in patients with diabetic macular edema
    • 22115710
    • Dugel PU, Blumenkranz MS, Haller JA et al (2012) A randomized, dose-escalation study of subconjunctival and intravitreal injections of sirolimus in patients with diabetic macular edema. Ophthalmology 119:124-131
    • (2012) Ophthalmology , vol.119 , pp. 124-131
    • Dugel, P.U.1    Blumenkranz, M.S.2    Haller, J.A.3
  • 183
    • 33745646315 scopus 로고    scopus 로고
    • Ocular oxygenation and the treatment of diabetic retinopathy
    • 16818083
    • Stefansson E (2006) Ocular oxygenation and the treatment of diabetic retinopathy. Surv Ophthalmol 51:364-380
    • (2006) Surv Ophthalmol , vol.51 , pp. 364-380
    • Stefansson, E.1
  • 184
    • 0022475113 scopus 로고
    • Panretinal photocoagulation and retinal oxygenation in normal and diabetic cats
    • 3717248 1:STN:280:DyaL283jvFCltA%3D%3D
    • Stefansson E, Hatchell DL, Fisher BL et al (1986) Panretinal photocoagulation and retinal oxygenation in normal and diabetic cats. Am J Ophthalmol 101:657-664
    • (1986) Am J Ophthalmol , vol.101 , pp. 657-664
    • Stefansson, E.1    Hatchell, D.L.2    Fisher, B.L.3
  • 185
    • 0019756337 scopus 로고
    • Increased retinal oxygen supply following panretinal photocoagulation and vitrectomy and lensectomy
    • 1:STN:280:DyaL383gtVyjtg%3D%3D
    • Stefansson E, Landers MBI, Wolbarsht ML (1981) Increased retinal oxygen supply following panretinal photocoagulation and vitrectomy and lensectomy. Trans Am Acad Ophthalmol Soc 79:307-334
    • (1981) Trans Am Acad Ophthalmol Soc , vol.79 , pp. 307-334
    • Stefansson, E.1    Landers, M.B.I.2    Wolbarsht, M.L.3
  • 186
    • 84871904129 scopus 로고    scopus 로고
    • Intraocular VEGF level as a risk factor for postoperative complications after vitrectomy for proliferative diabetic retinopathy
    • Wakabayashi Y, Usui Y, Okunuki Y et al (2012) Intraocular VEGF level as a risk factor for postoperative complications after vitrectomy for proliferative diabetic retinopathy. Invest Ophthalmol Vis Sci 53:6403-6410
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 6403-6410
    • Wakabayashi, Y.1    Usui, Y.2    Okunuki, Y.3
  • 187
    • 0034890105 scopus 로고    scopus 로고
    • Vitrectomy for diabetic macular edema: The role of posterior vitreous detachment and epimacular membrane
    • 11530050 1:STN:280:DC%2BD3MvoslOlsA%3D%3D
    • Yamamoto T, Akabane N, Takeuchi S (2001) Vitrectomy for diabetic macular edema: the role of posterior vitreous detachment and epimacular membrane. Am J Ophthalmol 132:369-377
    • (2001) Am J Ophthalmol , vol.132 , pp. 369-377
    • Yamamoto, T.1    Akabane, N.2    Takeuchi, S.3
  • 188
    • 0034080197 scopus 로고    scopus 로고
    • Improved visual acuity following pars plana vitrectomy for diabetic cystoid macular edema and detached posterior hyaloid
    • 10783963 1:STN:280:DC%2BD3c3ksVGnuw%3D%3D
    • Ikeda T, Sato K, Katano T, Hayashi Y (2000) Improved visual acuity following pars plana vitrectomy for diabetic cystoid macular edema and detached posterior hyaloid. Retina 20:220-222
    • (2000) Retina , vol.20 , pp. 220-222
    • Ikeda, T.1    Sato, K.2    Katano, T.3    Hayashi, Y.4
  • 189
    • 0026659346 scopus 로고
    • Vitrectomy for diabetic macular traction and edema associated with posterior hyaloidal traction
    • 1594222 1:STN:280:DyaK383nvVOhuw%3D%3D
    • Lewis H, Abrams GW, Blumenkranz MS, Campo RV (1992) Vitrectomy for diabetic macular traction and edema associated with posterior hyaloidal traction. Ophthalmology 99:753-759
    • (1992) Ophthalmology , vol.99 , pp. 753-759
    • Lewis, H.1    Abrams, G.W.2    Blumenkranz, M.S.3    Campo, R.V.4
  • 190
    • 0033951575 scopus 로고    scopus 로고
    • Optical cross-sectional observation of resolved diabetic macular edema associated with vitreomacular separation
    • 10682989 1:STN:280:DC%2BD3c7ksFWqtg%3D%3D
    • Watanabe M, Oshima Y, Emi K (2000) Optical cross-sectional observation of resolved diabetic macular edema associated with vitreomacular separation. Am J Ophthalmol 129:264-267
    • (2000) Am J Ophthalmol , vol.129 , pp. 264-267
    • Watanabe, M.1    Oshima, Y.2    Emi, K.3
  • 191
    • 33947494271 scopus 로고    scopus 로고
    • Surgery for diabetic retinopathy
    • 17380064
    • Helbig H (2007) Surgery for diabetic retinopathy. Ophthalmologica 221:103-111
    • (2007) Ophthalmologica , vol.221 , pp. 103-111
    • Helbig, H.1
  • 192
    • 54249088395 scopus 로고    scopus 로고
    • Vitrectomy for diabetic macular oedema
    • 18437175 1:STN:280:DC%2BD1cnmtVyjsg%3D%3D
    • Laidlaw DA (2008) Vitrectomy for diabetic macular oedema. Eye 22:1337-1341
    • (2008) Eye , vol.22 , pp. 1337-1341
    • Laidlaw, D.A.1
  • 193
    • 77952891868 scopus 로고    scopus 로고
    • Vitrectomy outcomes in eyes with diabetic macular edema and vitreomacular traction
    • Diabetic Retinopathy Clinical Research Network Writing Committee, on behalf of the DRCR.net
    • Diabetic Retinopathy Clinical Research Network Writing Committee, on behalf of the DRCR.net (2010) Vitrectomy outcomes in eyes with diabetic macular edema and vitreomacular traction. Ophthalmology 117:1087-1093.e3
    • (2010) Ophthalmology , vol.117
  • 194
    • 66149104784 scopus 로고    scopus 로고
    • Long-term follow-up of vitrectomy for diffuse non tractional diabetic macular edema
    • 19289987
    • Kumagai K, Furukawa M, Ogino N et al (2009) Long-term follow-up of vitrectomy for diffuse non tractional diabetic macular edema. Retina 29:464-472
    • (2009) Retina , vol.29 , pp. 464-472
    • Kumagai, K.1    Furukawa, M.2    Ogino, N.3
  • 195
    • 0034122047 scopus 로고    scopus 로고
    • Resolution of diabetic macular edema after surgical removal of the posterior hyaloid and the inner limiting membrane
    • 10783944 1:STN:280:DC%2BD3c3ksVGgsg%3D%3D
    • Gandorfer A, Messmer EM, Ulbig MW, Kampik A (2000) Resolution of diabetic macular edema after surgical removal of the posterior hyaloid and the inner limiting membrane. Retina 20:126-133
    • (2000) Retina , vol.20 , pp. 126-133
    • Gandorfer, A.1    Messmer, E.M.2    Ulbig, M.W.3    Kampik, A.4
  • 196
    • 15044349368 scopus 로고    scopus 로고
    • Inhibitors of ocular neovascularization: Promises and potential problems
    • 15784876 1:CAS:528:DC%2BD2MXis1Crtr8%3D
    • van Wijngaarden P, Coster DJ, Williams KA (2005) Inhibitors of ocular neovascularization: promises and potential problems. JAMA 293:1509-1513
    • (2005) JAMA , vol.293 , pp. 1509-1513
    • Van Wijngaarden, P.1    Coster, D.J.2    Williams, K.A.3
  • 198
    • 0025289369 scopus 로고
    • Early vitrectomy for severe vitreous hemorrhage in diabetic retinopathy. Four-year results of a randomized trial: Diabetic Retinopathy Vitrectomy Study Report 5
    • Diabetic Retinopathy Vitrectomy Study Group
    • Diabetic Retinopathy Vitrectomy Study Group (1990) Early vitrectomy for severe vitreous hemorrhage in diabetic retinopathy. Four-year results of a randomized trial: Diabetic Retinopathy Vitrectomy Study Report 5. Arch Ophthalmol 108:958-964
    • (1990) Arch Ophthalmol , vol.108 , pp. 958-964
  • 199
    • 0023140305 scopus 로고
    • Results and prognostic factors in vitrectomy for diabetic traction retinal detachment of the macula
    • 2436603 1:STN:280:DyaL2s7osVWhsQ%3D%3D
    • Thompson JT, de Bustros S, Michels RG, Rice TA (1987) Results and prognostic factors in vitrectomy for diabetic traction retinal detachment of the macula. Arch Ophthalmol 105:497-502
    • (1987) Arch Ophthalmol , vol.105 , pp. 497-502
    • Thompson, J.T.1    De Bustros, S.2    Michels, R.G.3    Rice, T.A.4
  • 200
    • 0024318229 scopus 로고
    • Results of vitrectomy for diabetic traction retinal detachments using the en bloc excision technique
    • 2740077 1:STN:280:DyaL1M3ps1ahsQ%3D%3D
    • Williams DF, Williams GA, Hartz A et al (1989) Results of vitrectomy for diabetic traction retinal detachments using the en bloc excision technique. Ophthalmology 96:752-758
    • (1989) Ophthalmology , vol.96 , pp. 752-758
    • Williams, D.F.1    Williams, G.A.2    Hartz, A.3
  • 201
    • 42049101181 scopus 로고    scopus 로고
    • Combined rhegmatogenous and traction retinal detachment in proliferative diabetic retinopathy: Clinical manifestations and surgical outcome
    • 18347622
    • Yang CM, Su PY, Yeh PT, Chen MS (2008) Combined rhegmatogenous and traction retinal detachment in proliferative diabetic retinopathy: clinical manifestations and surgical outcome. Can J Ophthalmol 43:192-198
    • (2008) Can J Ophthalmol , vol.43 , pp. 192-198
    • Yang, C.M.1    Su, P.Y.2    Yeh, P.T.3    Chen, M.S.4
  • 202
    • 39349092418 scopus 로고    scopus 로고
    • Extended silicone oil tamponade in primary vitrectomy for complex retinal detachment in proliferative diabetic retinopathy: A long-term follow-up study
    • 18050123
    • Shen YD, Yang CM (2007) Extended silicone oil tamponade in primary vitrectomy for complex retinal detachment in proliferative diabetic retinopathy: a long-term follow-up study. Eur J Ophthalmol 17:954-960
    • (2007) Eur J Ophthalmol , vol.17 , pp. 954-960
    • Shen, Y.D.1    Yang, C.M.2
  • 203
    • 0033499624 scopus 로고    scopus 로고
    • Corneal epithelial defects following vitrectomy surgery using hand-held, sew-on, and noncontact viewing lenses
    • 10458292 1:STN:280:DyaK1MzosFCktg%3D%3D
    • Virata SR, Kylstra JA, Singh HT (1999) Corneal epithelial defects following vitrectomy surgery using hand-held, sew-on, and noncontact viewing lenses. Retina 19:287-290
    • (1999) Retina , vol.19 , pp. 287-290
    • Virata, S.R.1    Kylstra, J.A.2    Singh, H.T.3
  • 204
    • 40549095316 scopus 로고    scopus 로고
    • Predictive clinical features and outcomes of vitrectomy for proliferative diabetic retinopathy
    • 18303158 1:STN:280:DC%2BD1c7ktlOgtQ%3D%3D
    • Yorston D, Wickham L, Benson S et al (2008) Predictive clinical features and outcomes of vitrectomy for proliferative diabetic retinopathy. Br J Ophthalmol 92:365-368
    • (2008) Br J Ophthalmol , vol.92 , pp. 365-368
    • Yorston, D.1    Wickham, L.2    Benson, S.3
  • 205
    • 77949484223 scopus 로고    scopus 로고
    • Surgical management of the late complications of proliferative diabetic retinopathy
    • 20139916 1:STN:280:DC%2BC3c7ntlWnuw%3D%3D
    • Newman DK (2010) Surgical management of the late complications of proliferative diabetic retinopathy. Eye 24:441-449
    • (2010) Eye , vol.24 , pp. 441-449
    • Newman, D.K.1
  • 206
    • 84859761446 scopus 로고    scopus 로고
    • Surgical and visual outcome following 20-gauge vitrectomy in proliferative diabetic retinopathy over a 10-year period, evidence for change in practice
    • 22241020 1:STN:280:DC%2BC38vgtlSltw%3D%3D
    • Gupta B, Wong R, Sivaprasad S, Williamson TH (2012) Surgical and visual outcome following 20-gauge vitrectomy in proliferative diabetic retinopathy over a 10-year period, evidence for change in practice. Eye 26:576-582
    • (2012) Eye , vol.26 , pp. 576-582
    • Gupta, B.1    Wong, R.2    Sivaprasad, S.3    Williamson, T.H.4
  • 207
    • 0038826991 scopus 로고    scopus 로고
    • Intravitreal triamcinolone acetonide as an additional tool in pars plana vitrectomy for proliferative diabetic retinopathy
    • 12841570 1:STN:280:DC%2BD3szht1GrtQ%3D%3D
    • Jonas JB, Söfker A, Degenring R (2003) Intravitreal triamcinolone acetonide as an additional tool in pars plana vitrectomy for proliferative diabetic retinopathy. Eur J Ophthalmol 13:468-473
    • (2003) Eur J Ophthalmol , vol.13 , pp. 468-473
    • Jonas, J.B.1    Söfker, A.2    Degenring, R.3
  • 208
    • 44149128412 scopus 로고    scopus 로고
    • Intravitreal triamcinolone reduces the morphologic changes of ciliary body after pars plana vitrectomy for retinal vascular diseases
    • 18378211 1:CAS:528:DC%2BD1cXmt1Ontrs%3D
    • Lee GH, Ahn JK, Park YG (2008) Intravitreal triamcinolone reduces the morphologic changes of ciliary body after pars plana vitrectomy for retinal vascular diseases. Am J Ophthalmol 145:1037-1044
    • (2008) Am J Ophthalmol , vol.145 , pp. 1037-1044
    • Lee, G.H.1    Ahn, J.K.2    Park, Y.G.3
  • 209
    • 84862907417 scopus 로고    scopus 로고
    • Combination of vitrectomy, IVTA, and laser photocoagulation for diabetic macular edema unresponsive to prior treatments; 3-year results
    • 22160508
    • Kim YT, Kang SW, Kim SJ et al (2012) Combination of vitrectomy, IVTA, and laser photocoagulation for diabetic macular edema unresponsive to prior treatments; 3-year results. Graefes Arch Clin Exp Ophthalmol 250:679-984
    • (2012) Graefes Arch Clin Exp Ophthalmol , vol.250 , pp. 679-984
    • Kim, Y.T.1    Kang, S.W.2    Kim, S.J.3
  • 210
    • 44649202664 scopus 로고    scopus 로고
    • One-year results of a multicenter controlled clinical trial of triamcinolone in pars plana vitrectomy
    • 18431588 1:CAS:528:DC%2BD1cXmtlygsrk%3D
    • Yamakiri K, Sakamoto T, Noda Y et al (2008) One-year results of a multicenter controlled clinical trial of triamcinolone in pars plana vitrectomy. Graefes Arch Clin Exp Ophthalmol 246:959-966
    • (2008) Graefes Arch Clin Exp Ophthalmol , vol.246 , pp. 959-966
    • Yamakiri, K.1    Sakamoto, T.2    Noda, Y.3
  • 211
    • 43549104713 scopus 로고    scopus 로고
    • Injection of intravitreal bevacizumab (Avastin) as a preoperative adjunct before vitrectomy surgery in the treatment of severe proliferative diabetic retinopathy (PDR)
    • 18286296 1:CAS:528:DC%2BD1cXlsVGitLw%3D
    • Rizzo S, Genovesi-Ebert F, Di Bartolo E et al (2008) Injection of intravitreal bevacizumab (Avastin) as a preoperative adjunct before vitrectomy surgery in the treatment of severe proliferative diabetic retinopathy (PDR). Graefes Arch Clin Exp Ophthalmol 246:837-842
    • (2008) Graefes Arch Clin Exp Ophthalmol , vol.246 , pp. 837-842
    • Rizzo, S.1    Genovesi-Ebert, F.2    Di Bartolo, E.3
  • 212
    • 0033885481 scopus 로고    scopus 로고
    • Fibrovascular ingrowth and recurrent haemorrhage following diabetic vitrectomy
    • 10906084 1:STN:280:DC%2BD3cvhslClsw%3D%3D
    • West JF, Gregor ZJ (2000) Fibrovascular ingrowth and recurrent haemorrhage following diabetic vitrectomy. Br J Ophthalmol 84:822-825
    • (2000) Br J Ophthalmol , vol.84 , pp. 822-825
    • West, J.F.1    Gregor, Z.J.2
  • 213
    • 67349285875 scopus 로고    scopus 로고
    • Microincision vitrectomy surgery and intravitreal bevacizumab as a surgical adjunct to treat diabetic traction retinal detachment
    • 19269033
    • Oshima Y, Shima C, Wakabayashi T et al (2009) Microincision vitrectomy surgery and intravitreal bevacizumab as a surgical adjunct to treat diabetic traction retinal detachment. Ophthalmology 116:927-938
    • (2009) Ophthalmology , vol.116 , pp. 927-938
    • Oshima, Y.1    Shima, C.2    Wakabayashi, T.3
  • 214
    • 38949099070 scopus 로고    scopus 로고
    • Tractional retinal detachment following intravitreal bevacizumab (Avastin) in patients with severe proliferative diabetic retinopathy
    • 17965108 1:STN:280:DC%2BD1c%2FmvFWhsA%3D%3D
    • Arevalo JF, Maia M, Flynn HW Jr et al (2008) Tractional retinal detachment following intravitreal bevacizumab (Avastin) in patients with severe proliferative diabetic retinopathy. Br J Ophthalmol 92:213-216
    • (2008) Br J Ophthalmol , vol.92 , pp. 213-216
    • Arevalo, J.F.1    Maia, M.2    Flynn, Jr.H.W.3
  • 216
    • 26844520874 scopus 로고    scopus 로고
    • Pooled efficacy results from two multinational randomized controlled clinical trials of a single intravitreous injection of highly purified ovine hyaluronidase (Vitrase) for the management of vitreous hemorrhage
    • 16125661 1:CAS:528:DC%2BD2MXhtFSmt7%2FJ
    • Kuppermann BD, Thomas EL, de Smet MD et al (2005) Pooled efficacy results from two multinational randomized controlled clinical trials of a single intravitreous injection of highly purified ovine hyaluronidase (Vitrase) for the management of vitreous hemorrhage. Am J Ophthalmol 140:573-584
    • (2005) Am J Ophthalmol , vol.140 , pp. 573-584
    • Kuppermann, B.D.1    Thomas, E.L.2    De Smet, M.D.3
  • 217
    • 77949656341 scopus 로고    scopus 로고
    • A placebo-controlled trial of microplasmin intravitreous injection to facilitate posterior vitreous detachment before vitrectomy
    • 20138368
    • Benz MS, Packo KH, Gonzalez V et al (2010) A placebo-controlled trial of microplasmin intravitreous injection to facilitate posterior vitreous detachment before vitrectomy. Ophthalmology 117:791-797
    • (2010) Ophthalmology , vol.117 , pp. 791-797
    • Benz, M.S.1    Packo, K.H.2    Gonzalez, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.