메뉴 건너뛰기




Volumn 116, Issue 6, 2009, Pages 1142-1150

Randomized Trial of Intravitreal Bevacizumab Alone or Combined with Triamcinolone versus Macular Photocoagulation in Diabetic Macular Edema

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; TRIAMCINOLONE;

EID: 67349168190     PISSN: 01616420     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ophtha.2009.01.011     Document Type: Article
Times cited : (183)

References (45)
  • 2
    • 33748968004 scopus 로고    scopus 로고
    • Retina
    • Vaughn D., Asbury T., and Riordan-Eva P. (Eds), Appleton & Lange, Stamford, CT
    • Hardy R.A., and Crawford J.B. Retina. In: Vaughn D., Asbury T., and Riordan-Eva P. (Eds). General Ophthalmology. 15th ed. (1999), Appleton & Lange, Stamford, CT 178-199
    • (1999) General Ophthalmology. 15th ed. , pp. 178-199
    • Hardy, R.A.1    Crawford, J.B.2
  • 5
    • 0022347471 scopus 로고
    • Photocoagulation for diabetic macular edema. Early Treatment Diabetic Retinopathy Study report number 1
    • Early Treatment Diabetic Retinopathy Study Research Group
    • Early Treatment Diabetic Retinopathy Study Research Group. Photocoagulation for diabetic macular edema. Early Treatment Diabetic Retinopathy Study report number 1. Arch Ophthalmol 103 (1985) 1796-1806
    • (1985) Arch Ophthalmol , vol.103 , pp. 1796-1806
  • 6
    • 0026324005 scopus 로고
    • Modified grid laser photocoagulation for diffuse diabetic macular edema: long-term visual results
    • Lee C.M., and Olk R.J. Modified grid laser photocoagulation for diffuse diabetic macular edema: long-term visual results. Ophthalmology 98 (1991) 1594-1602
    • (1991) Ophthalmology , vol.98 , pp. 1594-1602
    • Lee, C.M.1    Olk, R.J.2
  • 7
    • 7444245438 scopus 로고    scopus 로고
    • Intravitreal triamcinolone for diabetic macular edema that persists after laser treatment: three-month efficacy and safety results of a prospective, randomized, double-masked, placebo-controlled clinical trial
    • Sutter F.K., Simpson J.M., and Gillies M.C. Intravitreal triamcinolone for diabetic macular edema that persists after laser treatment: three-month efficacy and safety results of a prospective, randomized, double-masked, placebo-controlled clinical trial. Ophthalmology 111 (2004) 2044-2049
    • (2004) Ophthalmology , vol.111 , pp. 2044-2049
    • Sutter, F.K.1    Simpson, J.M.2    Gillies, M.C.3
  • 8
    • 0842267262 scopus 로고    scopus 로고
    • Intravitreal triamcinolone acetonide for diabetic diffuse macular edema: preliminary results of a prospective controlled trial
    • Massin P., Audren F., Haouchine B., et al. Intravitreal triamcinolone acetonide for diabetic diffuse macular edema: preliminary results of a prospective controlled trial. Ophthalmology 111 (2004) 218-225
    • (2004) Ophthalmology , vol.111 , pp. 218-225
    • Massin, P.1    Audren, F.2    Haouchine, B.3
  • 9
    • 33747623255 scopus 로고    scopus 로고
    • Intravitreal triamcinolone for refractory diabetic macular edema: two-year results of a double-masked, placebo-controlled, randomized clinical trial
    • Gillies M.C., Sutter F.K., Simpson J.M., et al. Intravitreal triamcinolone for refractory diabetic macular edema: two-year results of a double-masked, placebo-controlled, randomized clinical trial. Ophthalmology 113 (2006) 1533-1538
    • (2006) Ophthalmology , vol.113 , pp. 1533-1538
    • Gillies, M.C.1    Sutter, F.K.2    Simpson, J.M.3
  • 10
    • 33745884399 scopus 로고    scopus 로고
    • Intravitreal triamcinolone acetonide for diabetic macular edema: a prospective, randomized study
    • Jonas J.B., Kamppeter B.A., Harder B., et al. Intravitreal triamcinolone acetonide for diabetic macular edema: a prospective, randomized study. J Ocul Pharmacol Ther 22 (2006) 200-207
    • (2006) J Ocul Pharmacol Ther , vol.22 , pp. 200-207
    • Jonas, J.B.1    Kamppeter, B.A.2    Harder, B.3
  • 11
    • 33748260374 scopus 로고    scopus 로고
    • Intravitreal triamcinolone acetonide for diffuse diabetic macular oedema: 6-month results of a prospective controlled trial
    • Audren F., Erginay A., Haouchine B., et al. Intravitreal triamcinolone acetonide for diffuse diabetic macular oedema: 6-month results of a prospective controlled trial. Acta Ophthalmol Scand 84 (2006) 624-630
    • (2006) Acta Ophthalmol Scand , vol.84 , pp. 624-630
    • Audren, F.1    Erginay, A.2    Haouchine, B.3
  • 12
    • 25844513658 scopus 로고    scopus 로고
    • A phase II randomized double-masked trial of pegaptanib, an anti-vascular endothelial growth factor aptamer, for diabetic macular edema
    • Macugen Diabetic Retinopathy Study Group
    • Macugen Diabetic Retinopathy Study Group. A phase II randomized double-masked trial of pegaptanib, an anti-vascular endothelial growth factor aptamer, for diabetic macular edema. Ophthalmology 112 (2005) 1747-1757
    • (2005) Ophthalmology , vol.112 , pp. 1747-1757
  • 13
    • 33748957021 scopus 로고    scopus 로고
    • A pilot study of multiple intravitreal injections of ranibizumab in patients with center-involving clinically significant diabetic macular edema
    • Chun D.W., Heier J.S., Topping T.M., et al. A pilot study of multiple intravitreal injections of ranibizumab in patients with center-involving clinically significant diabetic macular edema. Ophthalmology 113 (2006) 1706-1712
    • (2006) Ophthalmology , vol.113 , pp. 1706-1712
    • Chun, D.W.1    Heier, J.S.2    Topping, T.M.3
  • 14
    • 33845745774 scopus 로고    scopus 로고
    • Intravitreal bevacizumab (Avastin) therapy for persistent diffuse diabetic macular edema
    • Haritoglou C., Kook D., Neubauer A., et al. Intravitreal bevacizumab (Avastin) therapy for persistent diffuse diabetic macular edema. Retina 26 (2006) 999-1005
    • (2006) Retina , vol.26 , pp. 999-1005
    • Haritoglou, C.1    Kook, D.2    Neubauer, A.3
  • 15
    • 33947542681 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and the potential therapeutic use of pegaptanib (Macugen) in diabetic retinopathy
    • Starita C., Patel M., Katz B., and Adamis A.P. Vascular endothelial growth factor and the potential therapeutic use of pegaptanib (Macugen) in diabetic retinopathy. Dev Ophthalmol 39 (2007) 122-148
    • (2007) Dev Ophthalmol , vol.39 , pp. 122-148
    • Starita, C.1    Patel, M.2    Katz, B.3    Adamis, A.P.4
  • 16
    • 33644680195 scopus 로고    scopus 로고
    • Triamcinolone acetonide destabilizes VEGF mRNA in Muller cells under continuous cobalt stimulation
    • Sears J.E., and Hoppe G. Triamcinolone acetonide destabilizes VEGF mRNA in Muller cells under continuous cobalt stimulation. Invest Ophthalmol Vis Sci 46 (2005) 4336-4341
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 4336-4341
    • Sears, J.E.1    Hoppe, G.2
  • 17
    • 0036943831 scopus 로고    scopus 로고
    • Diabetic retinopathy: more than meets the eye
    • Penn State Retina Research Group
    • Gardner T.W., Antonetti D.A., Barber A.J., et al., Penn State Retina Research Group. Diabetic retinopathy: more than meets the eye. Surv Ophthalmol 47 suppl (2002) S253-S262
    • (2002) Surv Ophthalmol , vol.47 , Issue.SUPPL
    • Gardner, T.W.1    Antonetti, D.A.2    Barber, A.J.3
  • 18
    • 0033400347 scopus 로고    scopus 로고
    • The pathogenesis of edema in diabetic maculopathy
    • Antcliff R.J., and Marshall J. The pathogenesis of edema in diabetic maculopathy. Semin Ophthalmol 14 (1999) 223-232
    • (1999) Semin Ophthalmol , vol.14 , pp. 223-232
    • Antcliff, R.J.1    Marshall, J.2
  • 19
    • 0042932650 scopus 로고    scopus 로고
    • Vitreous levels of interleukin-6 and vascular endothelial growth factor are related to diabetic macular edema
    • Funatsu H., Yamashita H., Ikeda T., et al. Vitreous levels of interleukin-6 and vascular endothelial growth factor are related to diabetic macular edema. Ophthalmology 110 (2003) 1690-1696
    • (2003) Ophthalmology , vol.110 , pp. 1690-1696
    • Funatsu, H.1    Yamashita, H.2    Ikeda, T.3
  • 20
    • 18244372934 scopus 로고    scopus 로고
    • Vitreous levels of vascular endothelial growth factor and intercellular adhesion molecule 1 are related to diabetic macular edema
    • Funatsu H., Yamashita H., Sakata K., et al. Vitreous levels of vascular endothelial growth factor and intercellular adhesion molecule 1 are related to diabetic macular edema. Ophthalmology 112 (2005) 806-816
    • (2005) Ophthalmology , vol.112 , pp. 806-816
    • Funatsu, H.1    Yamashita, H.2    Sakata, K.3
  • 21
    • 33748982649 scopus 로고    scopus 로고
    • Intravitreal bevacizumab (Avastin) in the treatment of proliferative diabetic retinopathy
    • Avery R.L., Pearlman J., Pieramici D.J., et al. Intravitreal bevacizumab (Avastin) in the treatment of proliferative diabetic retinopathy. Ophthalmology 113 (2006) 1695-1705
    • (2006) Ophthalmology , vol.113 , pp. 1695-1705
    • Avery, R.L.1    Pearlman, J.2    Pieramici, D.J.3
  • 22
    • 36749103212 scopus 로고    scopus 로고
    • Intravitreal bevacizumab (Avastin) injection alone or combined with triamcinolone versus macular photocoagulation as primary treatment of diabetic macular edema
    • Soheilian M., Ramezani A., Bijanzadeh B., et al. Intravitreal bevacizumab (Avastin) injection alone or combined with triamcinolone versus macular photocoagulation as primary treatment of diabetic macular edema. Retina 27 (2007) 1187-1195
    • (2007) Retina , vol.27 , pp. 1187-1195
    • Soheilian, M.1    Ramezani, A.2    Bijanzadeh, B.3
  • 23
    • 0017744944 scopus 로고    scopus 로고
    • Group sequential methods in the design and analysis of clinical trials
    • Pocock S.J. Group sequential methods in the design and analysis of clinical trials. Biometrika 64 (1997) 191-199
    • (1997) Biometrika , vol.64 , pp. 191-199
    • Pocock, S.J.1
  • 24
    • 33845251640 scopus 로고    scopus 로고
    • Vascular endothelial growth factor biology: clinical implications for ocular treatments
    • Bhisitkul R.B. Vascular endothelial growth factor biology: clinical implications for ocular treatments. Br J Ophthalmol 90 (2006) 1542-1547
    • (2006) Br J Ophthalmol , vol.90 , pp. 1542-1547
    • Bhisitkul, R.B.1
  • 25
    • 33749557195 scopus 로고    scopus 로고
    • What we don't know about Avastin might hurt us
    • Gillies M.C. What we don't know about Avastin might hurt us. Arch Ophthalmol 124 (2006) 1478-1479
    • (2006) Arch Ophthalmol , vol.124 , pp. 1478-1479
    • Gillies, M.C.1
  • 26
    • 34748876124 scopus 로고    scopus 로고
    • A phase II randomized clinical trial of intravitreal bevacizumab for diabetic macular edema
    • Diabetic Retinopathy Clinical Research Network
    • Diabetic Retinopathy Clinical Research Network. A phase II randomized clinical trial of intravitreal bevacizumab for diabetic macular edema. Ophthalmology 114 (2007) 1860-1867
    • (2007) Ophthalmology , vol.114 , pp. 1860-1867
  • 27
    • 33750989330 scopus 로고    scopus 로고
    • Effect of grid laser photocoagulation in diffuse diabetic macular edema in correlation to glycosylated haemoglobin (HbA1c)
    • Schmid K.E., Neumaier-Ammerer B., Stolba U., and Binder S. Effect of grid laser photocoagulation in diffuse diabetic macular edema in correlation to glycosylated haemoglobin (HbA1c). Graefes Arch Clin Exp Ophthalmol 244 (2006) 1446-1452
    • (2006) Graefes Arch Clin Exp Ophthalmol , vol.244 , pp. 1446-1452
    • Schmid, K.E.1    Neumaier-Ammerer, B.2    Stolba, U.3    Binder, S.4
  • 28
    • 33947581702 scopus 로고    scopus 로고
    • Primary intravitreal bevacizumab (Avastin) for diabetic macular edema: results from the at 6-month follow-up
    • Pan-American Collaborative Retina Study Group
    • Arevalo J.F., Fromow-Guerra J., Quiroz-Mercado H., et al., Pan-American Collaborative Retina Study Group. Primary intravitreal bevacizumab (Avastin) for diabetic macular edema: results from the at 6-month follow-up. Ophthalmology 114 (2007) 743-750
    • (2007) Ophthalmology , vol.114 , pp. 743-750
    • Arevalo, J.F.1    Fromow-Guerra, J.2    Quiroz-Mercado, H.3
  • 29
    • 0037015059 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo
    • Jin K., Zhu Y., Sun Y., et al. Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo. Proc Natl Acad Sci U S A 99 (2002) 11946-11950
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 11946-11950
    • Jin, K.1    Zhu, Y.2    Sun, Y.3
  • 30
    • 0034978562 scopus 로고    scopus 로고
    • Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
    • Oosthuyse B., Moons L., Storkebaum E., et al. Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration. Nat Genet 28 (2001) 131-138
    • (2001) Nat Genet , vol.28 , pp. 131-138
    • Oosthuyse, B.1    Moons, L.2    Storkebaum, E.3
  • 31
    • 41349107607 scopus 로고    scopus 로고
    • Intravitreal bevacizumab with or without triamcinolone for refractory diabetic macular edema
    • Ahmadieh H., Ramezani A., Shoeibi N., et al. Intravitreal bevacizumab with or without triamcinolone for refractory diabetic macular edema. Graefes Arch Clin Exp Ophthalmol 246 (2008) 483-489
    • (2008) Graefes Arch Clin Exp Ophthalmol , vol.246 , pp. 483-489
    • Ahmadieh, H.1    Ramezani, A.2    Shoeibi, N.3
  • 32
    • 43049104479 scopus 로고    scopus 로고
    • Comparative therapy evaluation of intravitreal bevacizumab and triamcinolone acetonide on persistent diffuse diabetic macular edema
    • Shimura M., Nakazawa T., Yasuda K., et al. Comparative therapy evaluation of intravitreal bevacizumab and triamcinolone acetonide on persistent diffuse diabetic macular edema. Am J Ophthalmol 145 (2008) 854-861
    • (2008) Am J Ophthalmol , vol.145 , pp. 854-861
    • Shimura, M.1    Nakazawa, T.2    Yasuda, K.3
  • 33
    • 0036240895 scopus 로고    scopus 로고
    • Intravitreal triamcinolone for refractory diabetic macular edema
    • Martidis A., Duker J.S., Greenberg P.B., et al. Intravitreal triamcinolone for refractory diabetic macular edema. Ophthalmology 109 (2002) 920-927
    • (2002) Ophthalmology , vol.109 , pp. 920-927
    • Martidis, A.1    Duker, J.S.2    Greenberg, P.B.3
  • 34
    • 0037398304 scopus 로고    scopus 로고
    • Intraocular concentration and pharmacokinetics of triamcinolone acetonide after a single intravitreal injection
    • Beer P.M., Bakri S.J., Singh R.J., et al. Intraocular concentration and pharmacokinetics of triamcinolone acetonide after a single intravitreal injection. Ophthalmology 110 (2003) 681-686
    • (2003) Ophthalmology , vol.110 , pp. 681-686
    • Beer, P.M.1    Bakri, S.J.2    Singh, R.J.3
  • 35
    • 0142244629 scopus 로고    scopus 로고
    • Infectious and presumed noninfectious endophthalmitis after intravitreal triamcinolone acetonide injection
    • Nelson M.L., Tennant M.T., Sivalingam A., et al. Infectious and presumed noninfectious endophthalmitis after intravitreal triamcinolone acetonide injection. Retina 23 (2003) 686-691
    • (2003) Retina , vol.23 , pp. 686-691
    • Nelson, M.L.1    Tennant, M.T.2    Sivalingam, A.3
  • 36
    • 33750051350 scopus 로고    scopus 로고
    • Intravitreal triamcinolone acetonide for diffuse diabetic macular edema: phase 2 trial comparing 4 mg vs 2 mg
    • Audren F., Lecleire-Collet A., Erginay A., et al. Intravitreal triamcinolone acetonide for diffuse diabetic macular edema: phase 2 trial comparing 4 mg vs 2 mg. Am J Ophthalmol 142 (2006) 794-799
    • (2006) Am J Ophthalmol , vol.142 , pp. 794-799
    • Audren, F.1    Lecleire-Collet, A.2    Erginay, A.3
  • 38
    • 4344693990 scopus 로고    scopus 로고
    • Subthreshold micropulse diode laser treatment in diabetic macular oedema
    • Laursen M.L., Moeller F., Sander B., and Sjoelie A.K. Subthreshold micropulse diode laser treatment in diabetic macular oedema. Br J Ophthalmol 88 (2004) 1173-1179
    • (2004) Br J Ophthalmol , vol.88 , pp. 1173-1179
    • Laursen, M.L.1    Moeller, F.2    Sander, B.3    Sjoelie, A.K.4
  • 39
    • 6344272096 scopus 로고    scopus 로고
    • Diabetic macular edema: a review of past, present, and future therapies
    • Thompson M.J., and Ip M.S. Diabetic macular edema: a review of past, present, and future therapies. Int Ophthalmol Clin 44 (2004) 51-67
    • (2004) Int Ophthalmol Clin , vol.44 , pp. 51-67
    • Thompson, M.J.1    Ip, M.S.2
  • 40
    • 0842332559 scopus 로고    scopus 로고
    • Surgical and other treatments of diabetic macular edema: an update
    • Christoforidis J.B., and D'Amico D.J. Surgical and other treatments of diabetic macular edema: an update. Int Ophthalmol Clin 44 (2004) 139-160
    • (2004) Int Ophthalmol Clin , vol.44 , pp. 139-160
    • Christoforidis, J.B.1    D'Amico, D.J.2
  • 41
    • 50249149459 scopus 로고    scopus 로고
    • A randomized trial comparing intravitreal triamcinolone acetonide and focal/grid photocoagulation for diabetic macular edema
    • Diabetic Retinopathy Clinical Research Network
    • Diabetic Retinopathy Clinical Research Network. A randomized trial comparing intravitreal triamcinolone acetonide and focal/grid photocoagulation for diabetic macular edema. Ophthalmology 115 (2008) 1447-1459
    • (2008) Ophthalmology , vol.115 , pp. 1447-1459
  • 42
    • 50249101748 scopus 로고    scopus 로고
    • A new look at an old treatment for diabetic macular edema
    • Schachat A.P. A new look at an old treatment for diabetic macular edema. Ophthalmology 115 (2008) 1445-1446
    • (2008) Ophthalmology , vol.115 , pp. 1445-1446
    • Schachat, A.P.1
  • 43
    • 38349042071 scopus 로고    scopus 로고
    • Can optical coherence tomography predict the outcome of laser photocoagulation for diabetic macular edema?
    • Estabrook E.J., Madhusudhana K.C., Hannan S.R., and Newsom R.S. Can optical coherence tomography predict the outcome of laser photocoagulation for diabetic macular edema?. Ophthalmic Surg Lasers Imaging 38 (2007) 478-483
    • (2007) Ophthalmic Surg Lasers Imaging , vol.38 , pp. 478-483
    • Estabrook, E.J.1    Madhusudhana, K.C.2    Hannan, S.R.3    Newsom, R.S.4
  • 44
    • 23044440795 scopus 로고    scopus 로고
    • Optical coherence tomography findings after an intravitreal injection of bevacizumab (Avastin) for macular edema from central retinal vein occlusion
    • Rosenfeld P.J., Fung A.E., and Puliafito C.A. Optical coherence tomography findings after an intravitreal injection of bevacizumab (Avastin) for macular edema from central retinal vein occlusion. Ophthalmic Surg Lasers Imaging 36 (2005) 336-339
    • (2005) Ophthalmic Surg Lasers Imaging , vol.36 , pp. 336-339
    • Rosenfeld, P.J.1    Fung, A.E.2    Puliafito, C.A.3
  • 45
    • 33748985366 scopus 로고    scopus 로고
    • Intravitreal injection of bevacizumab (Avastin) as adjunctive treatment of proliferative diabetic retinopathy
    • Mason III J.O., Nixon P.A., and White M.F. Intravitreal injection of bevacizumab (Avastin) as adjunctive treatment of proliferative diabetic retinopathy. Am J Ophthalmol 142 (2006) 685-688
    • (2006) Am J Ophthalmol , vol.142 , pp. 685-688
    • Mason III, J.O.1    Nixon, P.A.2    White, M.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.