메뉴 건너뛰기




Volumn 15, Issue 1, 2013, Pages 68-78

Positron emission tomography imaging of endometrial cancer using engineered Anti-EMP2 antibody fragments

Author keywords

Copper 64; Endometrial cancer; Epithelial membrane protein 2; Minibody; PET imaging

Indexed keywords

COPPER 64; EPITHELIAL MEMBRANE PROTEIN 2; EPITHELIAL MEMBRANE PROTEIN 2 ANTIBODY; EPITHELIAL MEMBRANE PROTEIN 2 ANTIBODY TETRAXETAN CU 64; RADIOPHARMACEUTICAL AGENT; RECOMBINANT ANTIBODY; TETRASPANIN; TETRAXETAN; UNCLASSIFIED DRUG;

EID: 84873084894     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-012-0558-y     Document Type: Article
Times cited : (17)

References (44)
  • 1
    • 33745312697 scopus 로고    scopus 로고
    • Expression of epithelial membrane protein-2 is associated with endometrial adenocarcinoma of unfavorable outcome
    • 16736513 10.1002/cncr.21957 1:CAS:528:DC%2BD28XntVymu7k%3D
    • Wadehra M, Natarajan S, Seligson DB et al (2006) Expression of epithelial membrane protein-2 is associated with endometrial adenocarcinoma of unfavorable outcome. Cancer 107:90-98
    • (2006) Cancer , vol.107 , pp. 90-98
    • Wadehra, M.1    Natarajan, S.2    Seligson, D.B.3
  • 2
    • 78349281133 scopus 로고    scopus 로고
    • Epithelial membrane protein-2 expression is an early predictor of endometrial cancer development
    • 20578181 10.1002/cncr.25259
    • Habeeb O, Goodglick L, Soslow RA et al (2010) Epithelial membrane protein-2 expression is an early predictor of endometrial cancer development. Cancer 116:4718-4726
    • (2010) Cancer , vol.116 , pp. 4718-4726
    • Habeeb, O.1    Goodglick, L.2    Soslow, R.A.3
  • 3
    • 77955104682 scopus 로고    scopus 로고
    • Epithelial membrane protein-2 is a novel therapeutic target in ovarian cancer
    • 20670949 10.1158/1078-0432.CCR-10-0368 1:CAS:528:DC%2BC3cXpsVCisbg%3D
    • Fu M, Maresh EL, Soslow RA et al (2010) Epithelial membrane protein-2 is a novel therapeutic target in ovarian cancer. Clin Cancer Res 16:3954-3963
    • (2010) Clin Cancer Res , vol.16 , pp. 3954-3963
    • Fu, M.1    Maresh, E.L.2    Soslow, R.A.3
  • 4
    • 2342514826 scopus 로고    scopus 로고
    • The tetraspan protein EMP2 modulates the surface expression of caveolins and glycosylphosphatidyl inositol-linked proteins
    • 14978215 10.1091/mbc.E03-07-0488 1:CAS:528:DC%2BD2cXjvFKjtrs%3D
    • Wadehra M, Goodglick L, Braun J (2004) The tetraspan protein EMP2 modulates the surface expression of caveolins and glycosylphosphatidyl inositol-linked proteins. Mol Biol Cell 15:2073-2083
    • (2004) Mol Biol Cell , vol.15 , pp. 2073-2083
    • Wadehra, M.1    Goodglick, L.2    Braun, J.3
  • 5
    • 34548824822 scopus 로고    scopus 로고
    • The tetraspan protein EMP2 regulates expression of caveolin-1
    • 17609206 10.1074/jbc.M702117200 1:CAS:528:DC%2BD2sXpslGjtb8%3D
    • Forbes A, Wadehra M, Mareninov S et al (2007) The tetraspan protein EMP2 regulates expression of caveolin-1. J Biol Chem 282:26542-26551
    • (2007) J Biol Chem , vol.282 , pp. 26542-26551
    • Forbes, A.1    Wadehra, M.2    Mareninov, S.3
  • 6
    • 58249085922 scopus 로고    scopus 로고
    • FAK activation and the role of epithelial membrane protein 2 (EMP2) in collagen gel contraction
    • 18469192 10.1167/iovs.07-1598
    • Morales SA, Mareninov S, Wadehra M et al (2009) FAK activation and the role of epithelial membrane protein 2 (EMP2) in collagen gel contraction. Invest Ophthalmol Vis Sci 50:462-469
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 462-469
    • Morales, S.A.1    Mareninov, S.2    Wadehra, M.3
  • 7
    • 27744606934 scopus 로고    scopus 로고
    • Epithelial membrane protein-2 regulates surface expression of alphavbeta3 integrin in the endometrium
    • 16216233 10.1016/j.ydbio.2005.09.003 1:CAS:528:DC%2BD2MXht1GhtL%2FM
    • Wadehra M, Forbes A, Pushkarna N et al (2005) Epithelial membrane protein-2 regulates surface expression of alphavbeta3 integrin in the endometrium. Dev Biol 287:336-345
    • (2005) Dev Biol , vol.287 , pp. 336-345
    • Wadehra, M.1    Forbes, A.2    Pushkarna, N.3
  • 8
    • 79957625159 scopus 로고    scopus 로고
    • Epithelial membrane protein-2 promotes endometrial tumor formation through activation of FAK and Src
    • 21637765 10.1371/journal.pone.0019945 1:CAS:528:DC%2BC3MXntVWqsLY%3D
    • Fu M, Rao R, Sudhakar D et al (2011) Epithelial membrane protein-2 promotes endometrial tumor formation through activation of FAK and Src. PLoS One 6:e19945
    • (2011) PLoS One , vol.6 , pp. 19945
    • Fu, M.1    Rao, R.2    Sudhakar, D.3
  • 9
    • 0035207920 scopus 로고    scopus 로고
    • Complexes of tetraspanins with integrins: More than meets the eye
    • 11739647 1:CAS:528:DC%2BD3MXptlKrt7k%3D
    • Berditchevski F (2001) Complexes of tetraspanins with integrins: more than meets the eye. J Cell Sci 114:4143-4151
    • (2001) J Cell Sci , vol.114 , pp. 4143-4151
    • Berditchevski, F.1
  • 10
    • 13444259476 scopus 로고    scopus 로고
    • The tetraspanin web modulates immune-signalling complexes
    • 15688041 10.1038/nri1548 1:CAS:528:DC%2BD2MXovFKguw%3D%3D
    • Levy S, Shoham T (2005) The tetraspanin web modulates immune-signalling complexes. Nat Rev Immunol 5:136-148
    • (2005) Nat Rev Immunol , vol.5 , pp. 136-148
    • Levy, S.1    Shoham, T.2
  • 11
    • 0030947554 scopus 로고    scopus 로고
    • The tetraspanin superfamily: Molecular facilitators
    • 9194523 1:CAS:528:DyaK2sXjvFahsLY%3D
    • Maecker HT, Todd SC, Levy S (1997) The tetraspanin superfamily: molecular facilitators. FASEB J 11:428-442
    • (1997) FASEB J , vol.11 , pp. 428-442
    • Maecker, H.T.1    Todd, S.C.2    Levy, S.3
  • 12
    • 79953203957 scopus 로고    scopus 로고
    • Structure-function analysis of tetraspanin CD151 reveals distinct requirements for tumor cell behaviors mediated by alpha3beta1 versus alpha6beta4 integrin
    • 21193415 10.1074/jbc.M110.173583 1:CAS:528:DC%2BC3MXisVyqtr8%3D
    • Zevian S, Winterwood NE, Stipp CS (2011) Structure-function analysis of tetraspanin CD151 reveals distinct requirements for tumor cell behaviors mediated by alpha3beta1 versus alpha6beta4 integrin. J Biol Chem 286:7496-7506
    • (2011) J Biol Chem , vol.286 , pp. 7496-7506
    • Zevian, S.1    Winterwood, N.E.2    Stipp, C.S.3
  • 13
    • 58149346081 scopus 로고    scopus 로고
    • Diabodies targeting epithelial membrane protein 2 reduce tumorigenicity of human endometrial cancer cell lines
    • 19010852 10.1158/1078-0432.CCR-08-1016 1:CAS:528:DC%2BD1cXhtlylur%2FP
    • Shimazaki K, Lepin EJ, Wei B et al (2008) Diabodies targeting epithelial membrane protein 2 reduce tumorigenicity of human endometrial cancer cell lines. Clin Cancer Res 14:7367-7377
    • (2008) Clin Cancer Res , vol.14 , pp. 7367-7377
    • Shimazaki, K.1    Lepin, E.J.2    Wei, B.3
  • 14
    • 0036176751 scopus 로고    scopus 로고
    • Positron emission tomography scanning: Current and future applications
    • 11818465 10.1146/annurev.med.53.082901.104028 1:CAS:528: DC%2BD38Xitl2msbk%3D
    • Czernin J, Phelps ME (2002) Positron emission tomography scanning: current and future applications. Annu Rev Med 53:89-112
    • (2002) Annu Rev Med , vol.53 , pp. 89-112
    • Czernin, J.1    Phelps, M.E.2
  • 15
    • 0036717382 scopus 로고    scopus 로고
    • Molecular imaging of cancer with positron emission tomography
    • 12209157 10.1038/nrc882 1:CAS:528:DC%2BD38Xmslanu7c%3D
    • Gambhir SS (2002) Molecular imaging of cancer with positron emission tomography. Nat Rev Cancer 2:683-693
    • (2002) Nat Rev Cancer , vol.2 , pp. 683-693
    • Gambhir, S.S.1
  • 17
    • 66149085319 scopus 로고    scopus 로고
    • Noninvasive imaging of alphaVbeta3 function as a predictor of the antimigratory and antiproliferative effects of dasatinib
    • 19318569 10.1158/0008-5472.CAN-08-3390 1:CAS:528:DC%2BD1MXjvVWit7s%3D
    • Dumont RA, Hildebrandt I, Su H et al (2009) Noninvasive imaging of alphaVbeta3 function as a predictor of the antimigratory and antiproliferative effects of dasatinib. Cancer Res 69:3173-3179
    • (2009) Cancer Res , vol.69 , pp. 3173-3179
    • Dumont, R.A.1    Hildebrandt, I.2    Su, H.3
  • 18
    • 33846207786 scopus 로고    scopus 로고
    • Positron emission tomography imaging for gynecologic malignancy
    • 17218850 10.1097/GCO.0b013e32801195c9
    • Lai CH, Yen TC, Chang TC (2007) Positron emission tomography imaging for gynecologic malignancy. Curr Opin Obstet Gynecol 19:37-41
    • (2007) Curr Opin Obstet Gynecol , vol.19 , pp. 37-41
    • Lai, C.H.1    Yen, T.C.2    Chang, T.C.3
  • 19
    • 5544270813 scopus 로고    scopus 로고
    • Positron emission tomography for prostate, bladder, and renal cancer
    • 15493005 10.1053/j.semnuclmed.2004.06.004
    • Schoder H, Larson SM (2004) Positron emission tomography for prostate, bladder, and renal cancer. Semin Nucl Med 34:274-292
    • (2004) Semin Nucl Med , vol.34 , pp. 274-292
    • Schoder, H.1    Larson, S.M.2
  • 20
    • 84873098896 scopus 로고    scopus 로고
    • Generation of single-chain Fv fragments and multivalent derivatives scFv-Fc and scFv-CH3 (minibodies)
    • R. Kontermann S. Dübel (eds) 2 Springer Berlin 10.1007/978-3-642- 01147-4-6
    • Olafsen T, Kenanova VE, Wu AM (2010) Generation of single-chain Fv fragments and multivalent derivatives scFv-Fc and scFv-CH3 (minibodies). In: Kontermann R, Dübel S (eds) Antibody engineering, vol 2. Springer, Berlin, pp 69-84
    • (2010) Antibody Engineering , pp. 69-84
    • Olafsen, T.1    Kenanova, V.E.2    Wu, A.M.3
  • 21
    • 34248655131 scopus 로고    scopus 로고
    • Tunable pharmacokinetics: Modifying the in vivo half-life of antibodies by directed mutagenesis of the Fc fragment
    • 17487194 10.1038/nprot.2006.322 1:CAS:528:DC%2BD2sXhtFagtrvO
    • Olafsen T, Kenanova VE, Wu AM (2006) Tunable pharmacokinetics: modifying the in vivo half-life of antibodies by directed mutagenesis of the Fc fragment. Nat Protoc 1:2048-2060
    • (2006) Nat Protoc , vol.1 , pp. 2048-2060
    • Olafsen, T.1    Kenanova, V.E.2    Wu, A.M.3
  • 22
    • 0037390921 scopus 로고    scopus 로고
    • Epithelial membrane protein-2 is expressed in discrete anatomical regions of the eye
    • 12710941 10.1016/S0014-4800(03)00009-1 1:CAS:528:DC%2BD3sXjtFWms7Y%3D
    • Wadehra M, Sulur GG, Braun J, Gordon LK, Goodglick L (2003) Epithelial membrane protein-2 is expressed in discrete anatomical regions of the eye. Exp Mol Pathol 74:106-112
    • (2003) Exp Mol Pathol , vol.74 , pp. 106-112
    • Wadehra, M.1    Sulur, G.G.2    Braun, J.3    Gordon, L.K.4    Goodglick, L.5
  • 23
    • 33645938293 scopus 로고    scopus 로고
    • Knockdown of the tetraspan protein epithelial membrane protein-2 inhibits implantation in the mouse
    • 16487956 10.1016/j.ydbio.2006.01.015 1:CAS:528:DC%2BD28Xjs1Wqtb4%3D
    • Wadehra M, Dayal M, Mainigi M et al (2006) Knockdown of the tetraspan protein epithelial membrane protein-2 inhibits implantation in the mouse. Dev Biol 292:430-441
    • (2006) Dev Biol , vol.292 , pp. 430-441
    • Wadehra, M.1    Dayal, M.2    Mainigi, M.3
  • 24
    • 0035083298 scopus 로고    scopus 로고
    • An improved method for conjugating monoclonal antibodies with N-hydroxysulfosuccinimidyl DOTA
    • 11312695 10.1021/bc0000886 1:CAS:528:DC%2BD3MXhsFKgsrk%3D
    • Lewis MR, Kao JY, Anderson AL, Shively JE, Raubitschek A (2001) An improved method for conjugating monoclonal antibodies with N- hydroxysulfosuccinimidyl DOTA. Bioconjug Chem 12:320-324
    • (2001) Bioconjug Chem , vol.12 , pp. 320-324
    • Lewis, M.R.1    Kao, J.Y.2    Anderson, A.L.3    Shively, J.E.4    Raubitschek, A.5
  • 25
    • 69449105856 scopus 로고    scopus 로고
    • Recombinant anti-CD20 antibody fragments for small-animal PET imaging of B-cell lymphomas
    • 19690034 10.2967/jnumed.108.060426 1:CAS:528:DC%2BD1MXhtFOrtbvL
    • Olafsen T, Betting D, Kenanova VE et al (2009) Recombinant anti-CD20 antibody fragments for small-animal PET imaging of B-cell lymphomas. J Nucl Med 50:1500-1508
    • (2009) J Nucl Med , vol.50 , pp. 1500-1508
    • Olafsen, T.1    Betting, D.2    Kenanova, V.E.3
  • 27
    • 0242409499 scopus 로고    scopus 로고
    • AMIDE: A free software tool for multimodality medical image analysis
    • 14649056 10.1162/153535003322556877
    • Loening AM, Gambhir SS (2003) AMIDE: a free software tool for multimodality medical image analysis. Mol Imaging 2:131-137
    • (2003) Mol Imaging , vol.2 , pp. 131-137
    • Loening, A.M.1    Gambhir, S.S.2
  • 28
    • 0031808317 scopus 로고    scopus 로고
    • Chromosomal mapping of Tmp (Emp1), Xmp (Emp2), and Ymp (Emp3), genes encoding membrane proteins related to Pmp22
    • 9615230 10.1006/geno.1998.5238 1:CAS:528:DyaK1cXjtlyltrY%3D
    • Ben-Porath I, Kozak CA, Benvenisty N (1998) Chromosomal mapping of Tmp (Emp1), Xmp (Emp2), and Ymp (Emp3), genes encoding membrane proteins related to Pmp22. Genomics 49:443-447
    • (1998) Genomics , vol.49 , pp. 443-447
    • Ben-Porath, I.1    Kozak, C.A.2    Benvenisty, N.3
  • 29
    • 0035877973 scopus 로고    scopus 로고
    • Epithelial membrane protein 2, a 4-transmembrane protein that suppresses B-cell lymphoma tumorigenicity
    • 11389031 10.1182/blood.V97.12.3890 1:CAS:528:DC%2BD3MXksVOqsbo%3D
    • Wang CX, Wadehra M, Fisk BC, Goodglick L, Braun J (2001) Epithelial membrane protein 2, a 4-transmembrane protein that suppresses B-cell lymphoma tumorigenicity. Blood 97:3890-3895
    • (2001) Blood , vol.97 , pp. 3890-3895
    • Wang, C.X.1    Wadehra, M.2    Fisk, B.C.3    Goodglick, L.4    Braun, J.5
  • 30
    • 42549114244 scopus 로고    scopus 로고
    • Steroid hormone regulation of EMP2 expression and localization in the endometrium
    • 18400107 10.1186/1477-7827-6-15
    • Wadehra M, Mainigi M, Morales SA et al (2008) Steroid hormone regulation of EMP2 expression and localization in the endometrium. Reprod Biol Endocrinol 6:15
    • (2008) Reprod Biol Endocrinol , vol.6 , pp. 15
    • Wadehra, M.1    Mainigi, M.2    Morales, S.A.3
  • 31
    • 77954890046 scopus 로고    scopus 로고
    • Positive progress in immunoPET - Not just a coincidence
    • 20578830 10.1089/cbr.2010.0776 1:CAS:528:DC%2BC3cXotFejtL0%3D
    • McCabe KE, Wu AM (2010) Positive progress in immunoPET - not just a coincidence. Cancer Biother Radiopharm 25:253-261
    • (2010) Cancer Biother Radiopharm , vol.25 , pp. 253-261
    • McCabe, K.E.1    Wu, A.M.2
  • 32
    • 4143080306 scopus 로고    scopus 로고
    • Pilot trial evaluating an 123I-labeled 80-kilodalton engineered anticarcinoembryonic antigen antibody fragment (cT84.66 minibody) in patients with colorectal cancer
    • 15297402 10.1158/1078-0432.CCR-03-0576 1:CAS:528:DC%2BD2cXmtlSitrY%3D
    • Wong JY, Chu DZ, Williams LE et al (2004) Pilot trial evaluating an 123I-labeled 80-kilodalton engineered anticarcinoembryonic antigen antibody fragment (cT84.66 minibody) in patients with colorectal cancer. Clin Cancer Res 10:5014-5021
    • (2004) Clin Cancer Res , vol.10 , pp. 5014-5021
    • Wong, J.Y.1    Chu, D.Z.2    Williams, L.E.3
  • 33
    • 0008486660 scopus 로고
    • Monoclonal antibody against epidermal growth factor receptor is internalized without stimulating receptor phosphorylation
    • 2424012 10.1073/pnas.83.11.3825 1:CAS:528:DyaL28XktlKgsr4%3D
    • Sunada H, Magun BE, Mendelsohn J, MacLeod CL (1986) Monoclonal antibody against epidermal growth factor receptor is internalized without stimulating receptor phosphorylation. Proc Natl Acad Sci USA 83:3825-3829
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 3825-3829
    • Sunada, H.1    Magun, B.E.2    Mendelsohn, J.3    MacLeod, C.L.4
  • 34
    • 79956209435 scopus 로고    scopus 로고
    • Evaluation of two internalizing carcinoembryonic antigen reporter genes for molecular imaging
    • 20628903 10.1007/s11307-010-0375-0
    • Barat B, Kenanova VE, Olafsen T, Wu AM (2011) Evaluation of two internalizing carcinoembryonic antigen reporter genes for molecular imaging. Mol Imaging Biol 13:526-535
    • (2011) Mol Imaging Biol , vol.13 , pp. 526-535
    • Barat, B.1    Kenanova, V.E.2    Olafsen, T.3    Wu, A.M.4
  • 35
    • 67651124762 scopus 로고    scopus 로고
    • Molecular imaging of cancer with copper-64 radiopharmaceuticals and positron emission tomography (PET)
    • 19530674 10.1021/ar800255q 1:CAS:528:DC%2BD1MXnt1Cmu7w%3D
    • Shokeen M, Anderson CJ (2009) Molecular imaging of cancer with copper-64 radiopharmaceuticals and positron emission tomography (PET). Acc Chem Res 42:832-841
    • (2009) Acc Chem Res , vol.42 , pp. 832-841
    • Shokeen, M.1    Anderson, C.J.2
  • 36
    • 66149192414 scopus 로고    scopus 로고
    • Radioimmunoimaging with longer-lived positron-emitting radionuclides: Potentials and challenges
    • 19125647 10.1021/bc800299f 1:CAS:528:DC%2BD1MXisVWktA%3D%3D
    • Nayak TK, Brechbiel MW (2009) Radioimmunoimaging with longer-lived positron-emitting radionuclides: potentials and challenges. Bioconjug Chem 20:825-841
    • (2009) Bioconjug Chem , vol.20 , pp. 825-841
    • Nayak, T.K.1    Brechbiel, M.W.2
  • 37
    • 0242353714 scopus 로고    scopus 로고
    • High-resolution microPET imaging of carcinoembryonic antigen-positive xenografts by using a copper-64-labeled engineered antibody fragment
    • 10880576 10.1073/pnas.150228297 1:CAS:528:DC%2BD3cXlt1Ggu7Y%3D
    • Wu AM, Yazaki PJ, Tsai S et al (2000) High-resolution microPET imaging of carcinoembryonic antigen-positive xenografts by using a copper-64-labeled engineered antibody fragment. Proc Natl Acad Sci USA 97:8495-8500
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 8495-8500
    • Wu, A.M.1    Yazaki, P.J.2    Tsai, S.3
  • 38
    • 68949197399 scopus 로고    scopus 로고
    • Monitoring therapeutic response of human ovarian cancer to 17-DMAG by noninvasive PET imaging with (64)Cu-DOTA-trastuzumab
    • 19440708 10.1007/s00259-009-1158-1 1:CAS:528:DC%2BD1MXps1CktrY%3D
    • Niu G, Li Z, Cao Q, Chen X (2009) Monitoring therapeutic response of human ovarian cancer to 17-DMAG by noninvasive PET imaging with (64)Cu-DOTA-trastuzumab. Eur J Nucl Med Mol Imaging 36:1510-1519
    • (2009) Eur J Nucl Med Mol Imaging , vol.36 , pp. 1510-1519
    • Niu, G.1    Li, Z.2    Cao, Q.3    Chen, X.4
  • 39
    • 63849194953 scopus 로고    scopus 로고
    • PET imaging of prostate cancer xenografts with a highly specific antibody against the prostate-specific membrane antigen
    • 19289418 10.2967/jnumed.108.058487
    • Elsasser-Beile U, Reischl G, Wiehr S et al (2009) PET imaging of prostate cancer xenografts with a highly specific antibody against the prostate-specific membrane antigen. J Nucl Med 50:606-611
    • (2009) J Nucl Med , vol.50 , pp. 606-611
    • Elsasser-Beile, U.1    Reischl, G.2    Wiehr, S.3
  • 40
    • 1542328068 scopus 로고    scopus 로고
    • Comparative in vivo stability of copper-64-labeled cross-bridged and conventional tetraazamacrocyclic complexes
    • 14998334 10.1021/jm030383m 1:CAS:528:DC%2BD2cXhtFagtLw%3D
    • Boswell CA, Sun X, Niu W et al (2004) Comparative in vivo stability of copper-64-labeled cross-bridged and conventional tetraazamacrocyclic complexes. J Med Chem 47:1465-1474
    • (2004) J Med Chem , vol.47 , pp. 1465-1474
    • Boswell, C.A.1    Sun, X.2    Niu, W.3
  • 41
    • 34249028629 scopus 로고    scopus 로고
    • Synthesis, characterization and in vivo studies of Cu(II)-64-labeled cross-bridged tetraazamacrocycle-amide complexes as models of peptide conjugate imaging agents
    • 17458949 10.1021/jm070204r 1:CAS:528:DC%2BD2sXksFChsLo%3D
    • Sprague JE, Peng Y, Fiamengo AL et al (2007) Synthesis, characterization and in vivo studies of Cu(II)-64-labeled cross-bridged tetraazamacrocycle-amide complexes as models of peptide conjugate imaging agents. J Med Chem 50:2527-2535
    • (2007) J Med Chem , vol.50 , pp. 2527-2535
    • Sprague, J.E.1    Peng, Y.2    Fiamengo, A.L.3
  • 42
    • 34547630542 scopus 로고    scopus 로고
    • [64Cu-NOTA-8-Aoc-BBN(7-14)NH2] targeting vector for positron-emission tomography imaging of gastrin-releasing peptide receptor-expressing tissues
    • 17626788 10.1073/pnas.0705347104 1:CAS:528:DC%2BD2sXos1ehtLw%3D
    • Prasanphanich AF, Nanda PK, Rold TL et al (2007) [64Cu-NOTA-8-Aoc-BBN(7- 14)NH2] targeting vector for positron-emission tomography imaging of gastrin-releasing peptide receptor-expressing tissues. Proc Natl Acad Sci USA 104:12462-12467
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 12462-12467
    • Prasanphanich, A.F.1    Nanda, P.K.2    Rold, T.L.3
  • 43
    • 59649105956 scopus 로고    scopus 로고
    • In vitro and in vivo analysis of [(64)Cu-NO2A-8-Aoc-BBN(7-14)NH(2)]: A site-directed radiopharmaceutical for positron-emission tomography imaging of T-47D human breast cancer tumors
    • 19217529 10.1016/j.nucmedbio.2008.11.005 1:CAS:528:DC%2BD1MXitVyhtbk%3D
    • Prasanphanich AF, Retzloff L, Lane SR et al (2009) In vitro and in vivo analysis of [(64)Cu-NO2A-8-Aoc-BBN(7-14)NH(2)]: a site-directed radiopharmaceutical for positron-emission tomography imaging of T-47D human breast cancer tumors. Nucl Med Biol 36:171-181
    • (2009) Nucl Med Biol , vol.36 , pp. 171-181
    • Prasanphanich, A.F.1    Retzloff, L.2    Lane, S.R.3
  • 44
    • 4444357241 scopus 로고    scopus 로고
    • Identification of genes differentially expressed in rat alveolar type i cells
    • 15205179 10.1165/rcmb.2003-0423OC 1:CAS:528:DC%2BD2cXnsVamsLo%3D
    • Dahlin K, Mager EM, Allen L et al (2004) Identification of genes differentially expressed in rat alveolar type I cells. Am J Respir Cell Mol Biol 31:309-316
    • (2004) Am J Respir Cell Mol Biol , vol.31 , pp. 309-316
    • Dahlin, K.1    Mager, E.M.2    Allen, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.